Type |
Details |
Score |
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
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|
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•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE79696 |
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Koerner MV |
Year: |
2018 |
Journal: |
Genes Dev |
Title: |
Toxicity of overexpressed MeCP2 is independent of HDAC3 activity. |
Volume: |
32 |
Issue: |
23-24 |
Pages: |
1514-1524 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi HK |
Year: |
2015 |
Journal: |
Hum Mol Genet |
Title: |
PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death. |
Volume: |
24 |
Issue: |
4 |
Pages: |
1127-41 |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE76410 |
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE31251 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Dash B |
Year: |
2019 |
Journal: |
Immunohorizons |
Title: |
The Interaction between NKAP and HDAC3 Is Critical for T Cell Maturation. |
Volume: |
3 |
Issue: |
8 |
Pages: |
352-367 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
HDAC3 and HDAC7 have opposite effects on osteoclast differentiation. |
|
•
•
•
•
•
|
Publication |
First Author: |
Mondello P |
Year: |
2020 |
Journal: |
Cancer Discov |
Title: |
Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma. |
Volume: |
10 |
Issue: |
3 |
Pages: |
440-459 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang MJ |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome. |
Volume: |
34 |
Issue: |
1 |
Pages: |
648-662 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Mochizuki K |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Repression of Somatic Genes by Selective Recruitment of HDAC3 by BLIMP1 Is Essential for Mouse Primordial Germ Cell Fate Determination. |
Volume: |
24 |
Issue: |
10 |
Pages: |
2682-2693.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fan L |
Year: |
2019 |
Journal: |
Metabolism |
Title: |
Adaptor protein APPL1 coordinates HDAC3 to modulate brown adipose tissue thermogenesis in mice. |
Volume: |
100 |
|
Pages: |
153955 |
|
•
•
•
•
•
|
Publication |
First Author: |
El-Hage P |
Year: |
2015 |
Journal: |
Mol Cancer Res |
Title: |
The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells. |
Volume: |
13 |
Issue: |
5 |
Pages: |
902-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Archer A |
Year: |
2012 |
Journal: |
Mol Endocrinol |
Title: |
Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice. |
Volume: |
26 |
Issue: |
12 |
Pages: |
1980-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Höpken UE |
Year: |
2017 |
Journal: |
Cancer Discov |
Title: |
Targeting HDAC3 in CREBBP-Mutant Lymphomas Counterstrikes Unopposed Enhancer Deacetylation of B-cell Signaling and Immune Response Genes. |
Volume: |
7 |
Issue: |
1 |
Pages: |
14-16 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
The Nuclear Envelope Protein Emerin Binds Directly to Histone Deacetylase 3 (HDAC3) and Activates HDAC3 Activity. |
|
•
•
•
•
•
|
Allele |
Name: |
histone deacetylase 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
428
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
233
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Zeng L |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Histone deacetylase 3 unconventional splicing mediates endothelial-to-mesenchymal transition through transforming growth factor β2. |
Volume: |
288 |
Issue: |
44 |
Pages: |
31853-66 |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE42537 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Pham L |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
HDAC3 and HDAC7 have opposite effects on osteoclast differentiation. |
Volume: |
286 |
Issue: |
14 |
Pages: |
12056-65 |
|
•
•
•
•
•
|
Allele |
Name: |
histone deacetylase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Publication |
First Author: |
Demmerle J |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
The nuclear envelope protein emerin binds directly to histone deacetylase 3 (HDAC3) and activates HDAC3 activity. |
Volume: |
287 |
Issue: |
26 |
Pages: |
22080-8 |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE72196 |
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
E-GEOD-72917 |
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Fischle W |
Year: |
2002 |
Journal: |
Mol Cell |
Title: |
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR. |
Volume: |
9 |
Issue: |
1 |
Pages: |
45-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Macfarlan T |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor. |
Volume: |
280 |
Issue: |
8 |
Pages: |
7346-58 |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This is the C-terminal domain found in NF-kappa-B-activating protein (Nkap) and a hypothetical open reading frame on chromosome 6, c6orf194. It is the HDAC3 binding domain required for transcriptional repression []. Nkap functions as a transcriptional repressor on Notch target genes, and is required for T cell development and acquisition of functional competency [, , ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Pajerowski AG |
Year: |
2009 |
Journal: |
Immunity |
Title: |
NKAP is a transcriptional repressor of notch signaling and is required for T cell development. |
Volume: |
30 |
Issue: |
5 |
Pages: |
696-707 |
|
•
•
•
•
•
|
Allele |
Name: |
nuclear receptor co-repressor 1; targeted mutation 1, Mitchell A Lazar |
Allele Type: |
Targeted |
Attribute String: |
Hypomorph, Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
nuclear receptor co-repressor 2; targeted mutation 1.1, Mitchell A Lazar |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang Y |
Year: |
2017 |
Journal: |
Cancer Discov |
Title: |
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas. |
Volume: |
7 |
Issue: |
1 |
Pages: |
38-53 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ncor1/Ncor1 |
Background: |
C57BL/6-Ncor1 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE57809 |
Experiment Type: |
RNA-Seq |
Study Type: |
Baseline |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
395
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
415
|
Fragment?: |
false |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsu FC |
Year: |
2011 |
Journal: |
J Exp Med |
Title: |
NKAP is required for T cell maturation and acquisition of functional competency. |
Volume: |
208 |
Issue: |
6 |
Pages: |
1291-304 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Sinha RA |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy. |
Volume: |
122 |
Issue: |
7 |
Pages: |
2428-38 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ncor1/Ncor1 Ncor2/Ncor2 |
Background: |
B6(FVB)-Ncor2 Ncor1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE49383 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao N |
Year: |
2015 |
Journal: |
Blood |
Title: |
Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl. |
Volume: |
125 |
Issue: |
6 |
Pages: |
941-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deliu E |
Year: |
2018 |
Journal: |
Nat Neurosci |
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