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Search results 501 to 600 out of 642 for Hdac3

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Type Details Score
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
HT Experiment
Series Id: GSE79696
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Koerner MV
Year: 2018
Journal: Genes Dev
Title: Toxicity of overexpressed MeCP2 is independent of HDAC3 activity.
Volume: 32
Issue: 23-24
Pages: 1514-1524
Publication
First Author: Choi HK
Year: 2015
Journal: Hum Mol Genet
Title: PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death.
Volume: 24
Issue: 4
Pages: 1127-41
HT Experiment
Series Id: GSE76410
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment
Series Id: GSE31251
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Dash B
Year: 2019
Journal: Immunohorizons
Title: The Interaction between NKAP and HDAC3 Is Critical for T Cell Maturation.
Volume: 3
Issue: 8
Pages: 352-367
Interaction Experiment
Description: HDAC3 and HDAC7 have opposite effects on osteoclast differentiation.
Publication
First Author: Mondello P
Year: 2020
Journal: Cancer Discov
Title: Selective Inhibition of HDAC3 Targets Synthetic Vulnerabilities and Activates Immune Surveillance in Lymphoma.
Volume: 10
Issue: 3
Pages: 440-459
Publication
First Author: Zhang MJ
Year: 2020
Journal: FASEB J
Title: The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome.
Volume: 34
Issue: 1
Pages: 648-662
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Mochizuki K
Year: 2018
Journal: Cell Rep
Title: Repression of Somatic Genes by Selective Recruitment of HDAC3 by BLIMP1 Is Essential for Mouse Primordial Germ Cell Fate Determination.
Volume: 24
Issue: 10
Pages: 2682-2693.e6
Publication  
First Author: Fan L
Year: 2019
Journal: Metabolism
Title: Adaptor protein APPL1 coordinates HDAC3 to modulate brown adipose tissue thermogenesis in mice.
Volume: 100
Pages: 153955
Publication
First Author: El-Hage P
Year: 2015
Journal: Mol Cancer Res
Title: The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells.
Volume: 13
Issue: 5
Pages: 902-12
Publication
First Author: Archer A
Year: 2012
Journal: Mol Endocrinol
Title: Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice.
Volume: 26
Issue: 12
Pages: 1980-90
Publication
First Author: Höpken UE
Year: 2017
Journal: Cancer Discov
Title: Targeting HDAC3 in CREBBP-Mutant Lymphomas Counterstrikes Unopposed Enhancer Deacetylation of B-cell Signaling and Immune Response Genes.
Volume: 7
Issue: 1
Pages: 14-16
Interaction Experiment
Description: The Nuclear Envelope Protein Emerin Binds Directly to Histone Deacetylase 3 (HDAC3) and Activates HDAC3 Activity.
Allele
Name: histone deacetylase 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Protein
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: false
Publication
First Author: Zeng L
Year: 2013
Journal: J Biol Chem
Title: Histone deacetylase 3 unconventional splicing mediates endothelial-to-mesenchymal transition through transforming growth factor β2.
Volume: 288
Issue: 44
Pages: 31853-66
HT Experiment
Series Id: GSE42537
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Pham L
Year: 2011
Journal: J Biol Chem
Title: HDAC3 and HDAC7 have opposite effects on osteoclast differentiation.
Volume: 286
Issue: 14
Pages: 12056-65
Allele
Name: histone deacetylase 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Publication
First Author: Demmerle J
Year: 2012
Journal: J Biol Chem
Title: The nuclear envelope protein emerin binds directly to histone deacetylase 3 (HDAC3) and activates HDAC3 activity.
Volume: 287
Issue: 26
Pages: 22080-8
HT Experiment
Series Id: GSE72196
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
HT Experiment
Series Id: E-GEOD-72917
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Fischle W
Year: 2002
Journal: Mol Cell
Title: Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.
Volume: 9
Issue: 1
Pages: 45-57
Publication
First Author: Macfarlan T
Year: 2005
Journal: J Biol Chem
Title: Human THAP7 is a chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressor.
Volume: 280
Issue: 8
Pages: 7346-58
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Protein Domain
Type: Domain
Description: This is the C-terminal domain found in NF-kappa-B-activating protein (Nkap) and a hypothetical open reading frame on chromosome 6, c6orf194. It is the HDAC3 binding domain required for transcriptional repression []. Nkap functions as a transcriptional repressor on Notch target genes, and is required for T cell development and acquisition of functional competency [, , ].
Publication
First Author: Pajerowski AG
Year: 2009
Journal: Immunity
Title: NKAP is a transcriptional repressor of notch signaling and is required for T cell development.
Volume: 30
Issue: 5
Pages: 696-707
Allele
Name: nuclear receptor co-repressor 1; targeted mutation 1, Mitchell A Lazar
Allele Type: Targeted
Attribute String: Hypomorph, Inserted expressed sequence
Allele  
Name: nuclear receptor co-repressor 2; targeted mutation 1.1, Mitchell A Lazar
Allele Type: Targeted
Publication
First Author: Jiang Y
Year: 2017
Journal: Cancer Discov
Title: CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.
Volume: 7
Issue: 1
Pages: 38-53
Strain
Attribute String: coisogenic, targeted mutation
Genotype
Symbol: Ncor1/Ncor1
Background: C57BL/6-Ncor1
Zygosity: hm
Has Mutant Allele: true
HT Experiment
Series Id: GSE57809
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
Protein
Organism: Mus musculus/domesticus
Length: 395  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 415  
Fragment?: false
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Hsu FC
Year: 2011
Journal: J Exp Med
Title: NKAP is required for T cell maturation and acquisition of functional competency.
Volume: 208
Issue: 6
Pages: 1291-304
Strain
Attribute String: targeted mutation, mutant strain
Publication
First Author: Sinha RA
Year: 2012
Journal: J Clin Invest
Title: Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy.
Volume: 122
Issue: 7
Pages: 2428-38
Genotype
Symbol: Ncor1/Ncor1 Ncor2/Ncor2
Background: B6(FVB)-Ncor2 Ncor1
Zygosity: cx
Has Mutant Allele: true
HT Experiment
Series Id: GSE49383
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Xiao N
Year: 2015
Journal: Blood
Title: Ott1 (Rbm15) regulates thrombopoietin response in hematopoietic stem cells through alternative splicing of c-Mpl.
Volume: 125
Issue: 6
Pages: 941-8
Publication
First Author: Deliu E
Year: 2018
Journal: Nat Neurosci
Title: Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental gene expression and cognition.
Volume: 21
Issue: 12
Pages: 1717-1727
Publication
First Author: Wei LN
Year: 2000
Journal: J Biol Chem
Title: Receptor-interacting protein 140 directly recruits histone deacetylases for gene silencing.
Volume: 275
Issue: 52
Pages: 40782-7
Publication
First Author: Nakagawa T
Year: 2020
Journal: iScience
Title: The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression.
Volume: 23
Issue: 4
Pages: 101030
Publication  
First Author: Sadler AJ
Year: 2015
Journal: Nat Commun
Title: The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF.
Volume: 6
Pages: 6795
Publication
First Author: Czimmerer Z
Year: 2018
Journal: Immunity
Title: The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages.
Volume: 48
Issue: 1
Pages: 75-90.e6
Publication
First Author: Gomis-Coloma C
Year: 2018
Journal: J Cell Biol
Title: Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells.
Volume: 217
Issue: 4
Pages: 1249-1268
Publication
First Author: Liao J
Year: 2018
Journal: Endocrinology
Title: HDAC3-Selective Inhibition Activates Brown and Beige Fat Through PRDM16.
Volume: 159
Issue: 7
Pages: 2520-2527
Publication
First Author: Thiagarajan D
Year: 2016
Journal: Cell Rep
Title: Aldose Reductase Acts as a Selective Derepressor of PPARγ and the Retinoic Acid Receptor.
Volume: 15
Issue: 1
Pages: 181-96
Publication
First Author: Pardo M
Year: 2017
Journal: JCI Insight
Title: Intranasal siRNA administration reveals IGF2 deficiency contributes to impaired cognition in Fragile X syndrome mice.
Volume: 2
Issue: 6
Pages: e91782
Publication
First Author: Iershov A
Year: 2019
Journal: Nat Commun
Title: The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα.
Volume: 10
Issue: 1
Pages: 1566
Publication
First Author: Escande C
Year: 2014
Journal: Aging Cell
Title: Deleted in Breast Cancer 1 regulates cellular senescence during obesity.
Volume: 13
Issue: 5
Pages: 951-3
Publication
First Author: Zullo JM
Year: 2012
Journal: Cell
Title: DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina.
Volume: 149
Issue: 7
Pages: 1474-87