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Search results 801 to 876 out of 876 for Syp

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Type Details Score
Publication
29180744 | J:255932
First Author: Mario Gonzalez-Meljem J
Year: 2017
Journal: Nat Commun
Title: Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.
Volume: 8
Issue: 1
Pages: 1819
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Publication
22627288 | J:185531
First Author: Wu H
Year: 2012
Journal: Development
Title: β-Catenin gain of function in muscles impairs neuromuscular junction formation.
Volume: 139
Issue: 13
Pages: 2392-404
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Publication
28069946 | J:239523
First Author: Chen CM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice.
Volume: 114
Issue: 4
Pages: E619-E628
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Publication
26743624 | J:229471
First Author: Branchfield K
Year: 2016
Journal: Science
Title: Pulmonary neuroendocrine cells function as airway sensors to control lung immune response.
Volume: 351
Issue: 6274
Pages: 707-10
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Publication
27292642 | J:238301
First Author: Henley KD
Year: 2016
Journal: Cell Rep
Title: Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Volume: 15
Issue: 12
Pages: 2637-2650
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Publication
29922981 | J:274446
First Author: Wei W
Year: 2019
Journal: Mol Neurobiol
Title: Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.
Volume: 56
Issue: 3
Pages: 1719-1736
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Publication
25063451 | J:214089
First Author: Hale MA
Year: 2014
Journal: Development
Title: The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.
Volume: 141
Issue: 16
Pages: 3123-33
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Publication
37758766 | J:341383
First Author: Salamon I
Year: 2023
Journal: Nat Commun
Title: Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.
Volume: 14
Issue: 1
Pages: 6025
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Publication
28576773 | J:242899
First Author: Sinagoga KL
Year: 2017
Journal: Development
Title: Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.
Volume: 144
Issue: 13
Pages: 2402-2414
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Publication
34599305 | J:325971
First Author: Shibata M
Year: 2021
Journal: Nature
Title: Regulation of prefrontal patterning and connectivity by retinoic acid.
Volume: 598
Issue: 7881
Pages: 483-488
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Publication
14614146 | J:86704
First Author: Maynard TM
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A comprehensive analysis of 22q11 gene expression in the developing and adult brain.
Volume: 100
Issue: 24
Pages: 14433-8
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Publication
21884692 | J:178379
First Author: Richard AF
Year: 2011
Journal: Dev Biol
Title: Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression.
Volume: 359
Issue: 2
Pages: 303-20
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Publication
28827394 | J:245768
First Author: Landry-Truchon K
Year: 2017
Journal: Development
Title: HOXA5 plays tissue-specific roles in the developing respiratory system.
Volume: 144
Issue: 19
Pages: 3547-3561
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Publication
31323030 | J:279716
First Author: Braitsch CM
Year: 2019
Journal: PLoS Biol
Title: LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation.
Volume: 17
Issue: 7
Pages: e3000382
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Publication
24613359 | J:211830
First Author: Um JW
Year: 2014
Journal: Cell Rep
Title: Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.
Volume: 6
Issue: 6
Pages: 1096-1109
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Publication
26745185 | J:229930
 
First Author: Nechiporuk T
Year: 2016
Journal: Elife
Title: The REST remodeling complex protects genomic integrity during embryonic neurogenesis.
Volume: 5
Pages: e09584
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Syp<tm1Sud> | MGI:2179741
Name: synaptophysin; targeted mutation 1, Thomas C Sudhof
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Syp<em1Smoc> | MGI:7292657
Name: synaptophysin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein
P35235
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein
P35235-1
Organism: Mus musculus/domesticus
Length: 597  
Fragment?: false
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Strain
MGI:6429626 | C57BL/6JSmoc-Syp<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
7521735 | -
First Author: Lee CH
Year: 1994
Journal: Structure
Title: Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Volume: 2
Issue: 5
Pages: 423-38
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Interaction Experiment
Tanaka S (1996)
Description: Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
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GXD Expression
GXD Expression
 
Probe: MGI:6416298
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6416326
Age: embryonic day 18.5
Note: Expressed as postsynaptic aggregates. Significantly fewer synapse number (coexpressed Syp and Chrnb2/b4).
Specimen Label: 2a AGD-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6416298
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1844126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6416327
Age: embryonic day 18.5
Note: Expressed as postsynaptic aggregates. Significantly fewer synapse number (coexpressed Syp and Chrnb2/b4).
Specimen Label: 2a AGD-/-
Detected: true
Specimen Num: 2
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Publication
8639815 | -
First Author: Tauchi T
Year: 1996
Journal: Blood
Title: Tyrosine 425 within the activated erythropoietin receptor binds Syp, reduces the erythropoietin required for Syp tyrosine phosphorylation, and promotes mitogenesis.
Volume: 87
Issue: 11
Pages: 4495-501
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Publication
8662827 | -
First Author: Tanaka S
Year: 1996
Journal: J Biol Chem
Title: Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
Volume: 271
Issue: 24
Pages: 14610-6
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DO Term
DOID:0112035 | non-syndromic X-linked intellectual disability 96
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Protein Coding Gene
MGI:99511 | Ptpn11
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
8096088 | J:19469
First Author: Feng GS
Year: 1993
Journal: Science
Title: SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases.
Volume: 259
Issue: 5101
Pages: 1607-11
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Publication
7969452 | J:21373
First Author: Tamemoto H
Year: 1994
Journal: Nature
Title: Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.
Volume: 372
Issue: 6502
Pages: 182-6
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Publication
9175836 | J:40625
First Author: Shiratori T
Year: 1997
Journal: Immunity
Title: Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2.
Volume: 6
Issue: 5
Pages: 583-9
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Publication
23630575 | J:200568
First Author: Cheng CY
Year: 2013
Journal: PLoS One
Title: Detection and organ-specific ablation of neuroendocrine cells by synaptophysin locus-based BAC cassette in transgenic mice.
Volume: 8
Issue: 4
Pages: e60905
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Publication
8702915 | J:35137
First Author: Arrandale JM
Year: 1996
Journal: J Biol Chem
Title: Insulin signaling in mice expressing reduced levels of Syp.
Volume: 271
Issue: 35
Pages: 21353-8
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Publication
29104117 | J:257538
First Author: Somvanshi RK
Year: 2018
Journal: Biochim Biophys Acta
Title: Characterization of somatostatin receptors and associated signaling pathways in pancreas of R6/2 transgenic mice.
Volume: 1864
Issue: 2
Pages: 359-373
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Publication
38177238 | J:344447
First Author: Tripathi MK
Year: 2024
Journal: Sci Rep
Title: Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain.
Volume: 14
Issue: 1
Pages: 10
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Publication
39519239 | J:358441
 
First Author: Deng Z
Year: 2024
Journal: Int J Mol Sci
Title: Amino Acid Compound 2 (AAC2) Treatment Counteracts Insulin-Induced Synaptic Gene Expression and Seizure-Related Mortality in a Mouse Model of Alzheimer's Disease.
Volume: 25
Issue: 21
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Publication
20864515 | J:170202
First Author: Oriente F
Year: 2011
Journal: Diabetes
Title: Prep1 controls insulin glucoregulatory function in liver by transcriptional targeting of SHP1 tyrosine phosphatase.
Volume: 60
Issue: 1
Pages: 138-47
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Publication
8183548 | J:18769
First Author: Feng GS
Year: 1994
Journal: Oncogene
Title: Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.
Volume: 9
Issue: 6
Pages: 1545-50
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Publication
30030107 | J:329847
 
First Author: Gao J
Year: 2018
Journal: Brain Res Bull
Title: Deletion of asparagine endopeptidase reduces anxiety- and depressive-like behaviors and improves abilities of spatial cognition in mice.
Volume: 142
Pages: 147-155
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Publication
37503358 | J:351356
 
First Author: Garcia MG
Year: 2023
Journal: Brain Behav Immun Health
Title: Maternal separation differentially modulates early pathology by sex in 5xFAD Alzheimer's disease-transgenic mice.
Volume: 32
Pages: 100663
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Publication
28210208 | J:264914
 
First Author: Vanaveski T
Year: 2017
Journal: Front Neurosci
Title: Promoter-Specific Expression and Genomic Structure of IgLON Family Genes in Mouse.
Volume: 11
Pages: 38
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Publication
9890893 | J:317779
First Author: Lehr S
Year: 1999
Journal: Biochemistry
Title: Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.
Volume: 38
Issue: 1
Pages: 151-9
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Publication
30170608 | J:310386
First Author: Han L
Year: 2018
Journal: J Neuroinflammation
Title: ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior.
Volume: 15
Issue: 1
Pages: 246
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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