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Search results 1 to 100 out of 200 for Abca12

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0.042s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein
Organism: Mus musculus
Length: 148  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: ATP-binding cassette subfamily A member 12 (ABCA12) is linked to three related dyskeratinisation disorders: Harlequin ichthyosis (HI) [], lamellar ichthyosis type 2 [], and non-bullous congenital ichthyosiform erythroderma []. It may play an important role in lipid transport from the Golgi apparatus to lamellar granule in human granular layer keratinocytes [].Members of ABC (ATP-binding cassette) transporter subfamily A are full-length transporters [], which consist of a single long polypeptide chain organised into two tandemly arranged halves. Each half contains a membrane-spanning domain (MSD) followed by a cytoplasmic nucleotide binding domain (NBD) [].
Protein
Organism: Mus musculus
Length: 2595  
Fragment?: false
Protein
Organism: Mus musculus
Length: 2595  
Fragment?: false
Publication
First Author: Ursino GM
Year: 2020
Journal: EMBO Rep
Title: ABCA12 regulates insulin secretion from β-cells.
Volume: 21
Issue: 3
Pages: e48692
Publication    
First Author: Schaap FG
Year: 2002
Journal: GenBank Submission
Title: Mus musculus strain FVB Abca12 mRNA, partial cds
Pages: AF420436
Publication
First Author: Fu Y
Year: 2013
Journal: Cell Metab
Title: ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis.
Volume: 18
Issue: 2
Pages: 225-38
Publication
First Author: Zuo Y
Year: 2008
Journal: J Biol Chem
Title: ABCA12 maintains the epidermal lipid permeability barrier by facilitating formation of ceramide linoleic esters.
Volume: 283
Issue: 52
Pages: 36624-35
Publication
First Author: Akiyama M
Year: 2005
Journal: J Clin Invest
Title: Mutations in lipid transporter ABCA12 in harlequin ichthyosis and functional recovery by corrective gene transfer.
Volume: 115
Issue: 7
Pages: 1777-84
Publication
First Author: Lefévre C
Year: 2003
Journal: Hum Mol Genet
Title: Mutations in the transporter ABCA12 are associated with lamellar ichthyosis type 2.
Volume: 12
Issue: 18
Pages: 2369-78
Publication
First Author: Akiyama M
Year: 2008
Journal: Br J Dermatol
Title: Novel compound heterozygous nonsense and missense ABCA12 mutations lead to nonbullous congenital ichthyosiform erythroderma.
Volume: 158
Issue: 4
Pages: 864-7
Publication
First Author: Sakai K
Year: 2007
Journal: Exp Dermatol
Title: Localization of ABCA12 from Golgi apparatus to lamellar granules in human upper epidermal keratinocytes.
Volume: 16
Issue: 11
Pages: 920-6
Publication
First Author: Smyth I
Year: 2008
Journal: PLoS Genet
Title: A mouse model of harlequin ichthyosis delineates a key role for Abca12 in lipid homeostasis.
Volume: 4
Issue: 9
Pages: e1000192
Publication
First Author: Zhang L
Year: 2016
Journal: PLoS One
Title: Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.
Volume: 11
Issue: 8
Pages: e0161465
Protein
Organism: Mus musculus
Length: 719  
Fragment?: true
Protein
Organism: Mus musculus
Length: 839  
Fragment?: false
Protein
Organism: Mus musculus
Length: 2595  
Fragment?: false
Publication
First Author: Bungert S
Year: 2001
Journal: J Biol Chem
Title: Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: identification of N-linked glycosylation sites.
Volume: 276
Issue: 26
Pages: 23539-46
Publication
First Author: Coleman JA
Year: 2013
Journal: Biochim Biophys Acta
Title: Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport.
Volume: 1831
Issue: 3
Pages: 555-74
Publication
First Author: Yanagi T
Year: 2008
Journal: Hum Mol Genet
Title: Harlequin ichthyosis model mouse reveals alveolar collapse and severe fetal skin barrier defects.
Volume: 17
Issue: 19
Pages: 3075-83
Publication
First Author: Cottle DL
Year: 2020
Journal: Cell Rep Med
Title: Topical Aminosalicylic Acid Improves Keratinocyte Differentiation in an Inducible Mouse Model of Harlequin Ichthyosis.
Volume: 1
Issue: 8
Pages: 100129
Publication
First Author: Haller JF
Year: 2014
Journal: J Lipid Res
Title: Endogenous β-glucocerebrosidase activity in Abca12⁻/⁻epidermis elevates ceramide levels after topical lipid application but does not restore barrier function.
Volume: 55
Issue: 3
Pages: 493-503
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Yanagi T
Year: 2011
Journal: J Invest Dermatol
Title: AKT has an anti-apoptotic role in ABCA12-deficient keratinocytes.
Volume: 131
Issue: 9
Pages: 1942-5
Publication
First Author: Yanagi T
Year: 2010
Journal: Am J Pathol
Title: Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12-deficient harlequin ichthyosis model mice.
Volume: 177
Issue: 1
Pages: 106-18
GXD Expression      
Probe: MGI:6423354
Assay Type: RT-PCR
Annotation Date: 2020-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Stage: TS26
Assay Id: MGI:6423367
Age: embryonic day 18.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6423354
Assay Type: RT-PCR
Annotation Date: 2020-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752826
Stage: TS26
Assay Id: MGI:6423367
Age: embryonic day 18.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666522
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754922
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Note: Expression was not detected in the corpus striatum (lateral ganglionic eminence).
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697422
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276322
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Note: Expression was not detected in the face/soft tissues.
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1783822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665922
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1706822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1674822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1670622
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738222
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1654222
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777922
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684922
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619322
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1755022
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1733122
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736622
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Note: Expression was not detected in the genito-urinary system.
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610422
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876922
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276722
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753622
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619422
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3290622
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1795022
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1745822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278022
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Note: Expression was not detected in the pallidum (medial ganglionic eminence).
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3286922
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1778722
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738122
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752322
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267222
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284522
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1853522
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689622
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647022
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1842622
Pattern: Ubiquitous
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Image: MH3370; Specimen C4453
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274322
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309561
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3277822
Stage: TS22
Assay Id: MGI:5422929
Age: embryonic day 14.5
Detected: false
Specimen Num: 1