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Search results 1 to 100 out of 334 for Abca4

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication  
First Author: Quazi F
Year: 2012
Journal: Nat Commun
Title: ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer.
Volume: 3
Pages: 925
Publication
First Author: Wu L
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Light damage in Abca4 and Rpe65rd12 mice.
Volume: 55
Issue: 3
Pages: 1910-8
Publication
First Author: Han Z
Year: 2012
Journal: J Clin Invest
Title: DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.
Volume: 122
Issue: 9
Pages: 3221-6
Publication
First Author: Müller PL
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Monoallelic ABCA4 Mutations Appear Insufficient to Cause Retinopathy: A Quantitative Autofluorescence Study.
Volume: 56
Issue: 13
Pages: 8179-86
Publication
First Author: Maeda A
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Limited roles of Rdh8, Rdh12, and Abca4 in all-trans-retinal clearance in mouse retina.
Volume: 50
Issue: 11
Pages: 5435-43
Publication
First Author: Conley SM
Year: 2012
Journal: Biochim Biophys Acta
Title: Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt's dystrophy.
Volume: 1822
Issue: 7
Pages: 1169-79
Publication
First Author: Lenis TL
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration.
Volume: 115
Issue: 47
Pages: E11120-E11127
Publication
First Author: Molday LL
Year: 2018
Journal: Hum Mol Genet
Title: Localization and functional characterization of the p.Asn965Ser (N965S) ABCA4 variant in mice reveal pathogenic mechanisms underlying Stargardt macular degeneration.
Volume: 27
Issue: 2
Pages: 295-306
Publication
First Author: Quazi F
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: ATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal.
Volume: 111
Issue: 13
Pages: 5024-9
Publication
First Author: Charbel Issa P
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization.
Volume: 112
Issue: 27
Pages: 8415-20
Protein
Organism: Mus musculus
Length: 305  
Fragment?: true
Publication
First Author: Ma L
Year: 2011
Journal: J Biol Chem
Title: C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of Stargardt disease.
Volume: 286
Issue: 10
Pages: 7966-74
Publication
First Author: Anderson DMG
Year: 2017
Journal: Sci Rep
Title: Bis(monoacylglycero)phosphate lipids in the retinal pigment epithelium implicate lysosomal/endosomal dysfunction in a model of Stargardt disease and human retinas.
Volume: 7
Issue: 1
Pages: 17352
Publication
First Author: Trapani I
Year: 2015
Journal: Hum Mol Genet
Title: Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease.
Volume: 24
Issue: 23
Pages: 6811-25
Publication
First Author: Radu RA
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation.
Volume: 49
Issue: 9
Pages: 3821-9
Publication
First Author: Radu RA
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration.
Volume: 101
Issue: 16
Pages: 5928-33
Publication
First Author: Liu J
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.
Volume: 49
Issue: 2
Pages: 772-80
Publication
First Author: Bui TV
Year: 2006
Journal: J Biol Chem
Title: Characterization of native retinal fluorophores involved in biosynthesis of A2E and lipofuscin-associated retinopathies.
Volume: 281
Issue: 26
Pages: 18112-9
Publication
First Author: Tsybovsky Y
Year: 2011
Journal: Biochemistry
Title: Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4.
Volume: 50
Issue: 32
Pages: 6855-66
Publication
First Author: Anderson OA
Year: 2013
Journal: PLoS One
Title: A2E induces IL-1ß production in retinal pigment epithelial cells via the NLRP3 inflammasome.
Volume: 8
Issue: 6
Pages: e67263
Publication
First Author: Chen Y
Year: 2018
Journal: Nat Commun
Title: A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.
Volume: 9
Issue: 1
Pages: 1976
Publication
First Author: Zhang N
Year: 2015
Journal: Hum Mol Genet
Title: Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.
Volume: 24
Issue: 11
Pages: 3220-37
Publication
First Author: Secondi R
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: Fundus autofluorescence findings in a mouse model of retinal detachment.
Volume: 53
Issue: 9
Pages: 5190-7
Publication
First Author: Wu Y
Year: 2009
Journal: J Biol Chem
Title: Novel lipofuscin bisretinoids prominent in human retina and in a model of recessive Stargardt disease.
Volume: 284
Issue: 30
Pages: 20155-66
Publication
First Author: Radu RA
Year: 2011
Journal: J Biol Chem
Title: Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.
Volume: 286
Issue: 21
Pages: 18593-601
Publication
First Author: Perusek L
Year: 2015
Journal: J Biol Chem
Title: Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epithelium.
Volume: 290
Issue: 48
Pages: 29035-44
Publication
First Author: Yamamoto K
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: A novel bisretinoid of retina is an adduct on glycerophosphoethanolamine.
Volume: 52
Issue: 12
Pages: 9084-90
Publication
First Author: Maeda A
Year: 2009
Journal: J Biol Chem
Title: Involvement of all-trans-retinal in acute light-induced retinopathy of mice.
Volume: 284
Issue: 22
Pages: 15173-83
Publication
First Author: Lenis TL
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Complement modulation in the retinal pigment epithelium rescues photoreceptor degeneration in a mouse model of Stargardt disease.
Volume: 114
Issue: 15
Pages: 3987-3992
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Weng J
Year: 1999
Journal: Cell
Title: Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice.
Volume: 98
Issue: 1
Pages: 13-23
Publication
First Author: Mata NL
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration.
Volume: 97
Issue: 13
Pages: 7154-9
Publication
First Author: Mata NL
Year: 2001
Journal: Invest Ophthalmol Vis Sci
Title: Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration.
Volume: 42
Issue: 8
Pages: 1685-90
Publication
First Author: Fishkin NE
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate.
Volume: 102
Issue: 20
Pages: 7091-6
Publication
First Author: Guha S
Year: 2012
Journal: J Neurochem
Title: Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.
Volume: 122
Issue: 4
Pages: 823-33
Publication
First Author: Grey AC
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Spatial localization of A2E in the retinal pigment epithelium.
Volume: 52
Issue: 7
Pages: 3926-33
Publication
First Author: Lu W
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Oral Delivery of the P2Y12 Receptor Antagonist Ticagrelor Prevents Loss of Photoreceptors in an ABCA4-/- Mouse Model of Retinal Degeneration.
Volume: 60
Issue: 8
Pages: 3046-3053
Publication
First Author: Kim SR
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model.
Volume: 104
Issue: 49
Pages: 19273-8
Publication
First Author: Sparrow JR
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Quantitative fundus autofluorescence in mice: correlation with HPLC quantitation of RPE lipofuscin and measurement of retina outer nuclear layer thickness.
Volume: 54
Issue: 4
Pages: 2812-20
Publication
First Author: Tan LX
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Protective responses to sublytic complement in the retinal pigment epithelium.
Volume: 113
Issue: 31
Pages: 8789-94
Publication
First Author: Maiti P
Year: 2006
Journal: Biochemistry
Title: Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation.
Volume: 45
Issue: 3
Pages: 852-60
Publication
First Author: Qtaishat NM
Year: 2007
Journal: Curr Eye Res
Title: Preservation of retinoid influx into eye tissues of ABCR-deficient mice.
Volume: 32
Issue: 12
Pages: 1073-82
Publication  
First Author: Lu W
Year: 2018
Journal: Front Pharmacol
Title: The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration.
Volume: 9
Pages: 242
Publication
First Author: Kaur G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration.
Volume: 115
Issue: 36
Pages: 9014-9019
Publication
First Author: Charbel Issa P
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology.
Volume: 54
Issue: 8
Pages: 5602-12
Publication
First Author: Dobri N
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: A1120, a nonretinoid RBP4 antagonist, inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis.
Volume: 54
Issue: 1
Pages: 85-95
Publication
First Author: Prokopiou E
Year: 2018
Journal: Invest Ophthalmol Vis Sci
Title: Omega-3 Fatty Acids Supplementation: Therapeutic Potential in a Mouse Model of Stargardt Disease.
Volume: 59
Issue: 7
Pages: 2757-2767
Publication
First Author: Pawar AS
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Recovery of rod photoresponses in ABCR-deficient mice.
Volume: 49
Issue: 6
Pages: 2743-55
Publication
First Author: Guha S
Year: 2013
Journal: FASEB J
Title: Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor.
Volume: 27
Issue: 11
Pages: 4500-9
Publication
First Author: Bavik C
Year: 2015
Journal: PLoS One
Title: Visual Cycle Modulation as an Approach toward Preservation of Retinal Integrity.
Volume: 10
Issue: 5
Pages: e0124940
Publication
First Author: Azarian SM
Year: 1997
Journal: FEBS Lett
Title: The photoreceptor rim protein is an ABC transporter encoded by the gene for recessive Stargardt's disease (ABCR).
Volume: 409
Issue: 2
Pages: 247-52
Publication
First Author: Nasonkin I
Year: 1998
Journal: Hum Genet
Title: Mapping of the rod photoreceptor ABC transporter (ABCR) to 1p21-p22.1 and identification of novel mutations in Stargardt's disease.
Volume: 102
Issue: 1
Pages: 21-6
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876922
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1753622
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274322
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672722
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1647022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Image: MH3338; Specimen C4444
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3272922
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Note: Expression was not detected in the skeleton (limbs, shoulder, hip).
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1781522
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276322
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Note: Expression was not detected in the face/soft tissues.
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619422
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3286922
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3090122
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3283722
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1775122
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738222
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736622
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Note: Expression was not detected in the genito-urinary system.
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1745822
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284522
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666822
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309532
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5422900
Age: embryonic day 14.5
Detected: false
Specimen Num: 1