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Search results 1 to 100 out of 238 for Abca7

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: ATP-binding cassette subfamily A member 7 (ABCA7) belongs to the ABC transporter family, whose remembers are full-length transporters organised in two tandem halves, each with a hydrophobic TMD followed by a cytoplasmic NBD [].In macrophages, ABCA7 functions in phagocytosis and can be stabilised by HDL (high-density lipoprotein) apolipoproteins []. ABCA7 has been linked to Alzheimer's disease pathogenesis [, ]. It is also linked to Sjogrens syndrome, a chronic autoimmune disease characterised by the sicca symptoms of dry eyes and dry mouth [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Tanaka N
Year: 2010
Journal: J Lipid Res
Title: Helical apolipoproteins of high-density lipoprotein enhance phagocytosis by stabilizing ATP-binding cassette transporter A7.
Volume: 51
Issue: 9
Pages: 2591-9
Protein
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 2167  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2167  
Fragment?: false
Publication
First Author: Zhao QF
Year: 2015
Journal: Mol Neurobiol
Title: ABCA7 in Alzheimer's Disease.
Volume: 51
Issue: 3
Pages: 1008-16
Publication
First Author: Liao YC
Year: 2014
Journal: Neurobiol Aging
Title: ABCA7 gene and the risk of Alzheimer's disease in Han Chinese in Taiwan.
Volume: 35
Issue: 10
Pages: 2423.e7-2423.e13
Publication
First Author: Fu Y
Year: 2016
Journal: J Alzheimers Dis
Title: ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain.
Volume: 54
Issue: 2
Pages: 569-84
Publication
First Author: Logge W
Year: 2012
Journal: PLoS One
Title: Role of Abca7 in mouse behaviours relevant to neurodegenerative diseases.
Volume: 7
Issue: 9
Pages: e45959
Publication  
First Author: Li H
Year: 2016
Journal: Biosci Rep
Title: Abca7 deletion does not affect adult neurogenesis in the mouse.
Volume: 36
Issue: 2
Publication
First Author: Sakae N
Year: 2016
Journal: J Neurosci
Title: ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.
Volume: 36
Issue: 13
Pages: 3848-59
Publication
First Author: Linsel-Nitschke P
Year: 2005
Journal: J Lipid Res
Title: Potential role of ABCA7 in cellular lipid efflux to apoA-I.
Volume: 46
Issue: 1
Pages: 86-92
Publication
First Author: Aikawa T
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain.
Volume: 116
Issue: 47
Pages: 23790-23796
Publication
First Author: Bhatia S
Year: 2017
Journal: J Alzheimers Dis Rep
Title: Deletion of Alzheimer's Disease Risk Gene ABCA7 Alters White Adipose Tissue Development and Leptin Levels.
Volume: 1
Issue: 1
Pages: 237-247
Publication
First Author: Kim WS
Year: 2013
Journal: J Neurosci
Title: Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease.
Volume: 33
Issue: 10
Pages: 4387-94
Publication  
First Author: Nowyhed HN
Year: 2017
Journal: Sci Rep
Title: ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content.
Volume: 7
Pages: 40273
Publication
First Author: Borchers AT
Year: 2003
Journal: Clin Rev Allergy Immunol
Title: Immunopathogenesis of Sjögren's syndrome.
Volume: 25
Issue: 1
Pages: 89-104
Publication
First Author: Tanaka AR
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren's Syndrome.
Volume: 283
Issue: 5
Pages: 1019-25
Publication
First Author: Kim WS
Year: 2005
Journal: J Biol Chem
Title: Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.
Volume: 280
Issue: 5
Pages: 3989-95
Publication
First Author: Broccardo C
Year: 2001
Journal: Cytogenet Cell Genet
Title: Comparative analysis of the promoter structure and genomic organization of the human and mouse ABCA7 gene encoding a novel ABCA transporter.
Volume: 92
Issue: 3-4
Pages: 264-70
Publication
First Author: Meurs I
Year: 2012
Journal: PLoS One
Title: Effects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1.
Volume: 7
Issue: 3
Pages: e30984
Publication
First Author: Coleman JA
Year: 2013
Journal: Biochim Biophys Acta
Title: Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport.
Volume: 1831
Issue: 3
Pages: 555-74
Protein
Organism: Mus musculus/domesticus
Length: 2159  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2167  
Fragment?: false
Publication
First Author: Wang N
Year: 2003
Journal: J Biol Chem
Title: ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux.
Volume: 278
Issue: 44
Pages: 42906-12
Publication
First Author: Jehle AW
Year: 2006
Journal: J Cell Biol
Title: ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages.
Volume: 174
Issue: 4
Pages: 547-56
Publication
First Author: Satoh K
Year: 2015
Journal: J Biol Chem
Title: ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing.
Volume: 290
Issue: 40
Pages: 24152-65
Publication
First Author: Chan SL
Year: 2008
Journal: J Neurochem
Title: ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro.
Volume: 106
Issue: 2
Pages: 793-804
Publication
First Author: Morales CR
Year: 2008
Journal: Biochem Biophys Res Commun
Title: ATP-binding cassette transporters ABCA1, ABCA7, and ABCG1 in mouse spermatozoa.
Volume: 376
Issue: 3
Pages: 472-7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: B
Specimen Num: 1
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: H
Specimen Num: 2
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: L
Specimen Num: 3
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: Ln
Specimen Num: 4
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: Lg
Specimen Num: 5
GXD Expression      
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: S
Detected: true
Specimen Num: 6
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: K
Specimen Num: 7
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: A
Specimen Num: 8
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: T
Specimen Num: 9
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:2677983
Age: postnatal adult
Specimen Label: U
Specimen Num: 10
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2677985
Age: embryonic day 7.0
Specimen Label: 7
Specimen Num: 1
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:2677985
Age: embryonic day 8.0
Specimen Label: 8
Specimen Num: 2
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603914
Stage: TS14
Assay Id: MGI:2677985
Age: embryonic day 9.0
Specimen Label: 9
Specimen Num: 3
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2677985
Age: embryonic day 11.0
Specimen Label: 11
Specimen Num: 4
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603916
Stage: TS16
Assay Id: MGI:2677985
Age: embryonic day 10.0
Specimen Label: 10
Specimen Num: 5
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2677985
Age: embryonic day 12.0
Specimen Label: 12
Specimen Num: 6
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:2677985
Age: embryonic day 13.0
Specimen Label: 13
Specimen Num: 7
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:2677985
Age: embryonic day 14.0
Specimen Label: 14
Specimen Num: 8
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2677985
Age: embryonic day 15.0
Specimen Label: 15
Specimen Num: 9
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603924
Stage: TS24
Assay Id: MGI:2677985
Age: embryonic day 16.0
Specimen Label: 16
Specimen Num: 10
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2677985
Age: embryonic day 17.0
Specimen Label: 17
Specimen Num: 11
GXD Expression        
Probe: MGI:2677982
Assay Type: Northern blot
Annotation Date: 2003-10-31
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:2576527
Stage: TS27
Assay Id: MGI:2677985
Age: postnatal newborn
Specimen Label: P0
Specimen Num: 12
GXD Expression    
Probe: MGI:7281765
Assay Type: Western blot
Annotation Date: 2022-06-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752827
Stage: TS27
Assay Id: MGI:7281778
Age: postnatal newborn
Image: 2
Specimen Label: Abca12+/+ Epidermis
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:7281765
Assay Type: Western blot
Annotation Date: 2022-06-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752827
Stage: TS27
Assay Id: MGI:7281778
Age: postnatal newborn
Image: 2
Specimen Label: Abca12-/- Epidermis
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:7281765
Assay Type: Western blot
Annotation Date: 2022-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:7281877
Age: embryonic day 18.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7281765
Assay Type: Western blot
Annotation Date: 2022-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:7281877
Age: embryonic day 18.5
Image: 1
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7281765
Assay Type: Western blot
Annotation Date: 2022-06-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:7281877
Age: embryonic day 18.5
Image: 1
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1646922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Image: MH3339; Specimen C4444
Specimen Label: MH3339; Specimen C4444
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1647022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Image: MH3339; Specimen C4444
Specimen Label: MH3339; Specimen C4444
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754422
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777922
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3276722
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284522
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267322
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754922
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Note: Expression was not detected in the corpus striatum (lateral ganglionic eminence).
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267222
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3283722
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278022
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Note: Expression was not detected in the pallidum (medial ganglionic eminence).
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5309533
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689622
Stage: TS22
Assay Id: MGI:5422901
Age: embryonic day 14.5
Specimen Label: MH3339; Specimen C4444
Detected: false
Specimen Num: 1