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Search results 1 to 100 out of 315 for Abcb4

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0.072s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Hochrath K
Year: 2013
Journal: Bone
Title: Modeling hepatic osteodystrophy in Abcb4 deficient mice.
Volume: 55
Issue: 2
Pages: 501-11
Publication
First Author: Hochrath K
Year: 2012
Journal: FASEB J
Title: The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis.
Volume: 26
Issue: 12
Pages: 5081-91
Publication
First Author: Gros P
Year: 1988
Journal: Mol Cell Biol
Title: Cloning and characterization of a second member of the mouse mdr gene family.
Volume: 8
Issue: 7
Pages: 2770-8
Publication
First Author: Buschman E
Year: 1991
Journal: Mol Cell Biol
Title: Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes.
Volume: 11
Issue: 2
Pages: 595-603
Publication
First Author: Buschman E
Year: 1992
Journal: J Biol Chem
Title: mdr2 encodes P-glycoprotein expressed in the bile canalicular membrane as determined by isoform-specific antibodies.
Volume: 267
Issue: 25
Pages: 18093-9
Publication
First Author: Smit JJ
Year: 1993
Journal: Cell
Title: Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease.
Volume: 75
Issue: 3
Pages: 451-62
Publication
First Author: Ruetz S
Year: 1994
Journal: Cell
Title: Phosphatidylcholine translocase: a physiological role for the mdr2 gene.
Volume: 77
Issue: 7
Pages: 1071-81
Publication  
First Author: Chianale J
Year: 1996
Journal: Biochem J
Title: Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.
Volume: 314 ( Pt 3)
Pages: 781-6
Publication
First Author: Oude Elferink RP
Year: 1996
Journal: J Lipid Res
Title: Uncoupling of biliary phospholipid and cholesterol secretion in mice with reduced expression of mdr2 P-glycoprotein.
Volume: 37
Issue: 5
Pages: 1065-75
Publication
First Author: Croop JM
Year: 1989
Journal: Mol Cell Biol
Title: The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues.
Volume: 9
Issue: 3
Pages: 1346-50
Publication
First Author: Raymond M
Year: 1990
Journal: Mol Cell Biol
Title: Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.
Volume: 10
Issue: 4
Pages: 1642-51
Publication
First Author: Oude Elferink RP
Year: 1995
Journal: J Clin Invest
Title: Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse.
Volume: 95
Issue: 1
Pages: 31-8
Publication
First Author: Morita SY
Year: 2013
Journal: J Lipid Res
Title: Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes.
Volume: 54
Issue: 5
Pages: 1221-30
HT Experiment
Series Id: GSE26699
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Langheim S
Year: 2005
Journal: J Lipid Res
Title: ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile.
Volume: 46
Issue: 8
Pages: 1732-8
Publication
First Author: O'Hara SP
Year: 2017
Journal: J Biol Chem
Title: ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A.
Volume: 292
Issue: 12
Pages: 4833-4846
Publication
First Author: Cai SY
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice.
Volume: 306
Issue: 8
Pages: G670-6
Publication
First Author: Lammert F
Year: 2004
Journal: Hepatology
Title: Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis.
Volume: 39
Issue: 1
Pages: 117-28
Publication
First Author: Ikeda Y
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Enhancing effect of taurohyodeoxycholate on ABCB4-mediated phospholipid efflux.
Volume: 1864
Issue: 10
Pages: 1495-1502
Publication
First Author: Potikha T
Year: 2019
Journal: FASEB J
Title: Lack of galectin-1 exacerbates chronic hepatitis, liver fibrosis, and carcinogenesis in murine hepatocellular carcinoma model.
Volume: 33
Issue: 7
Pages: 7995-8007
Publication
First Author: Cariello M
Year: 2017
Journal: Sci Rep
Title: Long-term Administration of Nuclear Bile Acid Receptor FXR Agonist Prevents Spontaneous Hepatocarcinogenesis in Abcb4-/- Mice.
Volume: 7
Issue: 1
Pages: 11203
Publication  
First Author: Petruzzelli M
Year: 2016
Journal: Sci Rep
Title: Biliary Phospholipids Sustain Enterocyte Proliferation and Intestinal Tumor Progression via Nuclear Receptor Lrh1 in mice.
Volume: 6
Pages: 39278
Publication
First Author: Weber SN
Year: 2016
Journal: PLoS One
Title: TLR4 Deficiency Protects against Hepatic Fibrosis and Diethylnitrosamine-Induced Pre-Carcinogenic Liver Injury in Fibrotic Liver.
Volume: 11
Issue: 7
Pages: e0158819
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Mederacke I
Year: 2013
Journal: Nat Commun
Title: Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology.
Volume: 4
Pages: 2823
Publication
First Author: Singer S
Year: 2012
Journal: Mol Cell
Title: Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.
Volume: 48
Issue: 5
Pages: 799-810
Publication
First Author: Werner A
Year: 2002
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Fat malabsorption in essential fatty acid-deficient mice is not due to impaired bile formation.
Volume: 283
Issue: 4
Pages: G900-8
Publication
First Author: Strack I
Year: 2011
Journal: Lab Invest
Title: β-Adrenoceptor blockade in sclerosing cholangitis of Mdr2 knockout mice: antifibrotic effects in a model of nonsinusoidal fibrosis.
Volume: 91
Issue: 2
Pages: 252-61
Publication
First Author: Mann DA
Year: 2005
Journal: J Hepatol
Title: NF-kappaB: a signal for cancer.
Volume: 42
Issue: 4
Pages: 610-1
Publication
First Author: Katzenellenbogen M
Year: 2007
Journal: Mol Cancer Res
Title: Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice.
Volume: 5
Issue: 11
Pages: 1159-70
Publication
First Author: Voshol PJ
Year: 1998
Journal: Gastroenterology
Title: Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice.
Volume: 114
Issue: 5
Pages: 1024-34
Publication
First Author: Hulzebos CV
Year: 2005
Journal: Liver Int
Title: Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice.
Volume: 25
Issue: 3
Pages: 604-12
Publication
First Author: Pikarsky E
Year: 2004
Journal: Nature
Title: NF-kappaB functions as a tumour promoter in inflammation-associated cancer.
Volume: 431
Issue: 7007
Pages: 461-6
Publication
First Author: Chen L
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis.
Volume: 1865
Issue: 6
Pages: 1525-1539
Publication
First Author: Wu N
Year: 2017
Journal: FASEB J
Title: Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR-200b down-regulation.
Volume: 31
Issue: 10
Pages: 4305-4324
Publication
First Author: Groen AK
Year: 1995
Journal: Gastroenterology
Title: Regulation of protein secretion into bile: studies in mice with a disrupted mdr2 p-glycoprotein gene.
Volume: 109
Issue: 6
Pages: 1997-2006
Publication  
First Author: Angioni R
Year: 2020
Journal: Int J Mol Sci
Title: Administration of Human MSC-Derived Extracellular Vesicles for the Treatment of Primary Sclerosing Cholangitis: Preclinical Data in MDR2 Knockout Mice.
Volume: 21
Issue: 22
Publication
First Author: Sokolović A
Year: 2013
Journal: Biochim Biophys Acta
Title: Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathies.
Volume: 1832
Issue: 10
Pages: 1482-91
Publication
First Author: Van Nieuwkerk CM
Year: 1996
Journal: Gastroenterology
Title: Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene.
Volume: 111
Issue: 1
Pages: 165-71
Publication
First Author: Barikbin R
Year: 2018
Journal: Sci Rep
Title: Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2-/- mice.
Volume: 8
Issue: 1
Pages: 16238
Publication
First Author: Klopstock N
Year: 2009
Journal: PLoS One
Title: HCV tumor promoting effect is dependent on host genetic background.
Volume: 4
Issue: 4
Pages: e5025
Publication
First Author: Pacella I
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth.
Volume: 115
Issue: 28
Pages: E6546-E6555
Publication
First Author: Philips GM
Year: 2011
Journal: PLoS One
Title: Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer.
Volume: 6
Issue: 9
Pages: e23943
Publication  
First Author: Petrescu AD
Year: 2017
Journal: Int J Mol Sci
Title: Glucocorticoids Cause Gender-Dependent Reversal of Hepatic Fibrosis in the MDR2-Knockout Mouse Model.
Volume: 18
Issue: 11
Publication
First Author: De Vree JM
Year: 2000
Journal: Gastroenterology
Title: Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis.
Volume: 119
Issue: 6
Pages: 1720-30
Publication
First Author: Kruit JK
Year: 2005
Journal: Gastroenterology
Title: Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.
Volume: 128
Issue: 1
Pages: 147-56
Publication
First Author: Rajapaksha IG
Year: 2019
Journal: Hepatol Commun
Title: Liver-Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug-Resistant Gene 2-Knockout Mice.
Volume: 3
Issue: 12
Pages: 1656-1673
Publication
First Author: Mauad TH
Year: 1994
Journal: Am J Pathol
Title: Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis.
Volume: 145
Issue: 5
Pages: 1237-45
Publication
First Author: Fickert P
Year: 2004
Journal: Gastroenterology
Title: Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Volume: 127
Issue: 1
Pages: 261-74
Publication
First Author: Smith AJ
Year: 1998
Journal: Hepatology
Title: Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice.
Volume: 28
Issue: 2
Pages: 530-6
Publication
First Author: Shukla R
Year: 2013
Journal: Cell
Title: Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma.
Volume: 153
Issue: 1
Pages: 101-11
Publication
First Author: van Nieuwerk CM
Year: 1997
Journal: J Hepatol
Title: The role of bile salt composition in liver pathology of mdr2 (-/-) mice: differences between males and females.
Volume: 26
Issue: 1
Pages: 138-45
Publication
First Author: Voshol PJ
Year: 2000
Journal: Gastroenterology
Title: Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice.
Volume: 118
Issue: 1
Pages: 173-82
Publication
First Author: Horwitz E
Year: 2014
Journal: Cancer Discov
Title: Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.
Volume: 4
Issue: 6
Pages: 730-43
Publication
First Author: Werner A
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Lymphatic chylomicron size is inversely related to biliary phospholipid secretion in mice.
Volume: 290
Issue: 6
Pages: G1177-85
Publication
First Author: Minich DM
Year: 1999
Journal: Biochim Biophys Acta
Title: Biliary phospholipid secretion is not required for intestinal absorption and plasma status of linoleic acid in mice.
Volume: 1441
Issue: 1
Pages: 14-22
Publication
First Author: Kyritsi K
Year: 2017
Journal: Am J Pathol
Title: Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b.
Volume: 187
Issue: 7
Pages: 1551-1565
Publication
First Author: Barash H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks.
Volume: 107
Issue: 5
Pages: 2207-12
Publication
First Author: Malakar P
Year: 2019
Journal: Cancer Res
Title: Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2.
Volume: 79
Issue: 10
Pages: 2480-2493
Publication
First Author: Ikenaga N
Year: 2015
Journal: Am J Pathol
Title: A new Mdr2(-/-) mouse model of sclerosing cholangitis with rapid fibrosis progression, early-onset portal hypertension, and liver cancer.
Volume: 185
Issue: 2
Pages: 325-34
Publication
First Author: Katzenellenbogen M
Year: 2007
Journal: Mol Cancer Ther
Title: Molecular mechanisms of the chemopreventive effect on hepatocellular carcinoma development in Mdr2 knockout mice.
Volume: 6
Issue: 4
Pages: 1283-91
Publication
First Author: Katzenellenbogen M
Year: 2006
Journal: Cancer Res
Title: Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice.
Volume: 66
Issue: 8
Pages: 4001-10
Publication
First Author: Collino A
Year: 2018
Journal: PLoS Genet
Title: Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage.
Volume: 14
Issue: 5
Pages: e1007380
Publication  
First Author: Iannelli F
Year: 2014
Journal: Nat Commun
Title: Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency.
Volume: 5
Pages: 3850
Publication
First Author: Zhao JY
Year: 1993
Journal: Endocrinology
Title: Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells.
Volume: 133
Issue: 2
Pages: 521-8
Publication
First Author: Buschman E
Year: 1994
Journal: Cancer Res
Title: The inability of the mouse mdr2 gene to confer multidrug resistance is linked to reduced drug binding to the protein.
Volume: 54
Issue: 18
Pages: 4892-8
Publication
First Author: Higgins CF
Year: 1994
Journal: Curr Biol
Title: P-glycoprotein. To flip or not to flip?
Volume: 4
Issue: 3
Pages: 259-60
Publication
First Author: Wettergren Y
Year: 1995
Journal: Hereditas
Title: Colcemid resistance in murine SEWA cells: non-Pgy gene amplification at low levels of resistance and preferential Pgy2 gene amplification at high levels of resistance.
Volume: 122
Issue: 2
Pages: 125-34
Publication
First Author: Zimonjic DB
Year: 1996
Journal: Mamm Genome
Title: Localization of rat Pgy3 (mdr2) to the same region as Pgy2 (mdr1b) at 4q11-12.
Volume: 7
Issue: 8
Pages: 630-1
Publication
First Author: Elferink RP
Year: 1997
Journal: FASEB J
Title: Hepatic canalicular membrane 1: The role of mdr2 P-glycoprotein in hepatobiliary lipid transport.
Volume: 11
Issue: 1
Pages: 19-28
Publication
First Author: Tabibian JH
Year: 2013
Journal: Lab Invest
Title: Micro-computed tomography and nuclear magnetic resonance imaging for noninvasive, live-mouse cholangiography.
Volume: 93
Issue: 6
Pages: 733-43
Publication
First Author: Gamaev L
Year: 2021
Journal: Oncogene
Title: The pro-oncogenic effect of the lncRNA H19 in the development of chronic inflammation-mediated hepatocellular carcinoma.
Volume: 40
Issue: 1
Pages: 127-139
Publication  
First Author: Li X
Year: 2020
Journal: Cells
Title: Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions.
Volume: 9
Issue: 1
GXD Expression    
Probe: MGI:3655143
Assay Type: RT-PCR
Annotation Date: 2006-09-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3655155
Age: embryonic day 1.0
Image: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3655143
Assay Type: RT-PCR
Annotation Date: 2006-09-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3655155
Age: embryonic day 7.0
Image: 1
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:3655143
Assay Type: RT-PCR
Annotation Date: 2006-09-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603914
Stage: TS14
Assay Id: MGI:3655155
Age: embryonic day 9.0
Image: 1
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:3655143
Assay Type: RT-PCR
Annotation Date: 2006-09-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3655155
Age: embryonic day 3.5
Image: 1
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2678877
Assay Type: Northern blot
Annotation Date: 2003-11-12
Strength: Absent
Sex: Male
Emaps: EMAPS:3544028
Stage: TS28
Assay Id: MGI:2678897
Age: postnatal
Detected: false
Specimen Num: 1