| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
ATP-binding cassette subfamily C member 8 (ABCC8, also known as the sulphonylurea receptor SUR1) is a member of the ABC transporter family. ABCC8 is comprised of three transmembrane helical bundles, TMD0, TMD1 and TMD2. It also contains two cytosolic nucleotide binding domains (NBDs) located between TMD1 and TMD2 and in the cytoplasmic C-terminal domain, respectively []. It is a regulator of the potassium ATP channel. Its NBD domains control channel activity through their interaction with cytosolic nucleotides []. |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3820874 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2009-01-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3565022 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:3825727 |
| Age: |
embryonic day 14.5 |
| Image: |
Additional file 4 Abcc8 |
|
| Specimen Label: |
Additional file 4 Abcc8 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haghvirdizadeh P |
| Year: |
2014 |
| Journal: |
Gene |
| Title: |
ABCC8 genetic variants and risk of diabetes mellitus. |
| Volume: |
545 |
| Issue: |
2 |
| Pages: |
198-204 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ikle JM |
| Year: |
2022 |
| Journal: |
Islets |
| Title: |
Genome-edited zebrafish model of ABCC8 loss-of-function disease. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
200-209 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Simard JM |
| Year: |
2010 |
| Journal: |
Sci Transl Med |
| Title: |
Brief suppression of Abcc8 prevents autodestruction of spinal cord after trauma. |
| Volume: |
2 |
| Issue: |
28 |
| Pages: |
28ra29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muzyamba M |
| Year: |
2007 |
| Journal: |
Clin Endocrinol (Oxf) |
| Title: |
Complex ABCC8 DNA variations in congenital hyperinsulinism: lessons from functional studies. |
| Volume: |
67 |
| Issue: |
1 |
| Pages: |
115-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Andrikopoulos S |
| Year: |
2016 |
| Journal: |
J Endocrinol |
| Title: |
Identification of ABCC8 as a contributory gene to impaired early-phase insulin secretion in NZO mice. |
| Volume: |
228 |
| Issue: |
1 |
| Pages: |
61-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tata S |
| Year: |
2021 |
| Journal: |
J Neurotrauma |
| Title: |
Abcc8 (Sulfonylurea Receptor-1) Impact on Brain Atrophy after Traumatic Brain Injury Varies by Sex. |
| Volume: |
38 |
| Issue: |
17 |
| Pages: |
2473-2485 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aguilar-Bryan L |
| Year: |
1999 |
| Journal: |
Endocr Rev |
| Title: |
Molecular biology of adenosine triphosphate-sensitive potassium channels. |
| Volume: |
20 |
| Issue: |
2 |
| Pages: |
101-35 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rolim AL |
| Year: |
2014 |
| Journal: |
J Mol Endocrinol |
| Title: |
The insulin-sensitivity sulphonylurea receptor variant is associated with thyrotoxic paralysis. |
| Volume: |
53 |
| Issue: |
2 |
| Pages: |
295-301 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gloyn AL |
| Year: |
2006 |
| Journal: |
Hum Mutat |
| Title: |
Mutations in the genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) in diabetes mellitus and hyperinsulinism. |
| Volume: |
27 |
| Issue: |
3 |
| Pages: |
220-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Flanagan SE |
| Year: |
2009 |
| Journal: |
Hum Mutat |
| Title: |
Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism. |
| Volume: |
30 |
| Issue: |
2 |
| Pages: |
170-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lodwick D |
| Year: |
2014 |
| Journal: |
Biochem J |
| Title: |
Sulfonylurea receptors regulate the channel pore in ATP-sensitive potassium channels via an intersubunit salt bridge. |
| Volume: |
464 |
| Issue: |
3 |
| Pages: |
343-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cummings J |
| Year: |
2023 |
| Journal: |
J Neuroinflammation |
| Title: |
Abcc8 (sulfonylurea receptor-1) knockout mice exhibit reduced axonal injury, cytotoxic edema and cognitive dysfunction vs. wild-type in a cecal ligation and puncture model of sepsis. |
| Volume: |
20 |
| Issue: |
1 |
| Pages: |
12 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
158
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1588
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1588
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1087
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
899
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shimomura K |
| Year: |
2013 |
| Journal: |
Diabetes |
| Title: |
A mouse model of human hyperinsulinism produced by the E1506K mutation in the sulphonylurea receptor SUR1. |
| Volume: |
62 |
| Issue: |
11 |
| Pages: |
3797-806 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fisher C |
| Year: |
2024 |
| Journal: |
Diabetes |
| Title: |
Loss of ATP-Sensitive Potassium Channel Expression and Function in the Nervous System Decreases Opioid Sensitivity in a High-Fat Diet-Fed Mouse Model of Diet-Induced Obesity. |
| Volume: |
73 |
| Issue: |
8 |
| Pages: |
1244-1254 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Peterson SM |
| Year: |
2023 |
| Journal: |
Diabetes |
| Title: |
Optimization of a Glucagon-Like Peptide 1 Receptor Antagonist Antibody for Treatment of Hyperinsulinism. |
| Volume: |
72 |
| Issue: |
9 |
| Pages: |
1320-1329 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Osipovich AB |
| Year: |
2020 |
| Journal: |
Diabetes |
| Title: |
Excitotoxicity and Overnutrition Additively Impair Metabolic Function and Identity of Pancreatic ?-Cells. |
| Volume: |
69 |
| Issue: |
7 |
| Pages: |
1476-1491 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stancill JS |
| Year: |
2017 |
| Journal: |
Diabetes |
| Title: |
Chronic ?-Cell Depolarization Impairs ?-Cell Identity by Disrupting a Network of Ca(2+)-Regulated Genes. |
| Volume: |
66 |
| Issue: |
8 |
| Pages: |
2175-2187 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kurland DB |
| Year: |
2016 |
| Journal: |
J Neuroinflammation |
| Title: |
The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
130 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tsymbalyuk O |
| Year: |
2021 |
| Journal: |
Mol Pain |
| Title: |
SUR1, newly expressed in astrocytes, mediates neuropathic pain in a mouse model of peripheral nerve injury. |
| Volume: |
17 |
|
| Pages: |
17448069211006603 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aguilar-Bryan L |
| Year: |
1995 |
| Journal: |
Science |
| Title: |
Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. |
| Volume: |
268 |
| Issue: |
5209 |
| Pages: |
423-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Seghers V |
| Year: |
2000 |
| Journal: |
J Biol Chem |
| Title: |
Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion. |
| Volume: |
275 |
| Issue: |
13 |
| Pages: |
9270-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haspel D |
| Year: |
2005 |
| Journal: |
Diabetologia |
| Title: |
Crosstalk between membrane potential and cytosolic Ca2+ concentration in beta cells from Sur1-/- mice. |
| Volume: |
48 |
| Issue: |
5 |
| Pages: |
913-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Luu W |
| Year: |
2019 |
| Journal: |
Int J Mol Sci |
| Title: |
Modulation of SUR1 K(ATP) Channel Subunit Activity in the Peripheral Nervous System Reduces Mechanical Hyperalgesia after Nerve Injury in Mice. |
| Volume: |
20 |
| Issue: |
9 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Glendinning JI |
| Year: |
2020 |
| Journal: |
Am J Physiol Regul Integr Comp Physiol |
| Title: |
Olfaction contributes to the learned avidity for glucose relative to fructose in mice. |
| Volume: |
318 |
| Issue: |
5 |
| Pages: |
R901-R916 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mu?oz A |
| Year: |
2005 |
| Journal: |
Endocrinology |
| Title: |
Regulation of glucagon secretion at low glucose concentrations: evidence for adenosine triphosphate-sensitive potassium channel involvement. |
| Volume: |
146 |
| Issue: |
12 |
| Pages: |
5514-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kikuta T |
| Year: |
2005 |
| Journal: |
FEBS Lett |
| Title: |
Docking and fusion of insulin secretory granules in SUR1 knock out mouse beta-cells observed by total internal reflection fluorescence microscopy. |
| Volume: |
579 |
| Issue: |
7 |
| Pages: |
1602-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fisher C |
| Year: |
2019 |
| Journal: |
Front Neurosci |
| Title: |
Morphine Efficacy, Tolerance, and Hypersensitivity Are Altered After Modulation of SUR1 Subtype K(ATP) Channel Activity in Mice. |
| Volume: |
13 |
|
| Pages: |
1122 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Slucca M |
| Year: |
2010 |
| Journal: |
Diabetes |
| Title: |
ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation. |
| Volume: |
59 |
| Issue: |
1 |
| Pages: |
128-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakazaki M |
| Year: |
2002 |
| Journal: |
Diabetes |
| Title: |
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets. |
| Volume: |
51 |
| Issue: |
12 |
| Pages: |
3440-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Szollosi A |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels. |
| Volume: |
282 |
| Issue: |
3 |
| Pages: |
1747-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gier B |
| Year: |
2009 |
| Journal: |
J Clin Invest |
| Title: |
Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress. |
| Volume: |
119 |
| Issue: |
11 |
| Pages: |
3246-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pocai A |
| Year: |
2005 |
| Journal: |
Nature |
| Title: |
Hypothalamic K(ATP) channels control hepatic glucose production. |
| Volume: |
434 |
| Issue: |
7036 |
| Pages: |
1026-31 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sieg A |
| Year: |
2004 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
Epinephrine-induced hyperpolarization of islet cells without KATP channels. |
| Volume: |
286 |
| Issue: |
3 |
| Pages: |
E463-71 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Szollosi A |
| Year: |
2007 |
| Journal: |
J Biol Chem |
| Title: |
Overnight culture unmasks glucose-induced insulin secretion in mouse islets lacking ATP-sensitive K+ channels by improving the triggering Ca2+ signal. |
| Volume: |
282 |
| Issue: |
20 |
| Pages: |
14768-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Su Y |
| Year: |
2012 |
| Journal: |
Diabetes |
| Title: |
Hypothalamic leucine metabolism regulates liver glucose production. |
| Volume: |
61 |
| Issue: |
1 |
| Pages: |
85-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nenquin M |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells. |
| Volume: |
279 |
| Issue: |
31 |
| Pages: |
32316-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guiot Y |
| Year: |
2007 |
| Journal: |
Diabetologia |
| Title: |
Morphological localisation of sulfonylurea receptor 1 in endocrine cells of human, mouse and rat pancreas. |
| Volume: |
50 |
| Issue: |
9 |
| Pages: |
1889-1899 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakamura Y |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Targeting SUR1/Abcc8-type neuroendocrine KATP channels in pancreatic islet cells. |
| Volume: |
9 |
| Issue: |
3 |
| Pages: |
e91525 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gromada J |
| Year: |
2004 |
| Journal: |
Diabetes |
| Title: |
ATP-sensitive K+ channel-dependent regulation of glucagon release and electrical activity by glucose in wild-type and SUR1-/- mouse alpha-cells. |
| Volume: |
53 Suppl 3 |
|
| Pages: |
S181-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Doliba NM |
| Year: |
2004 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine. |
| Volume: |
286 |
| Issue: |
5 |
| Pages: |
E834-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eliasson L |
| Year: |
2003 |
| Journal: |
J Gen Physiol |
| Title: |
SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells. |
| Volume: |
121 |
| Issue: |
3 |
| Pages: |
181-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Huang W |
| Year: |
2008 |
| Journal: |
Am J Physiol Endocrinol Metab |
| Title: |
Fasting-induced suppression of LH secretion does not require activation of ATP-sensitive potassium channels. |
| Volume: |
295 |
| Issue: |
6 |
| Pages: |
E1439-46 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li C |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
A signaling role of glutamine in insulin secretion. |
| Volume: |
279 |
| Issue: |
14 |
| Pages: |
13393-401 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu M |
| Year: |
2022 |
| Journal: |
Aging Cell |
| Title: |
Role of upregulation of the K(ATP) channel subunit SUR1 in dopaminergic neuron degeneration in Parkinson's disease. |
| Volume: |
21 |
| Issue: |
5 |
| Pages: |
e13618 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cai M |
| Year: |
2016 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Epigenetic regulation of glucose-stimulated osteopontin (OPN) expression in diabetic kidney. |
| Volume: |
469 |
| Issue: |
1 |
| Pages: |
108-113 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cai M |
| Year: |
2018 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Role of osteopontin and its regulation in pancreatic islet. |
| Volume: |
495 |
| Issue: |
1 |
| Pages: |
1426-1431 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bancila V |
| Year: |
2005 |
| Journal: |
J Biol Chem |
| Title: |
Two SUR1-specific histidine residues mandatory for zinc-induced activation of the rat KATP channel. |
| Volume: |
280 |
| Issue: |
10 |
| Pages: |
8793-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Slepchenko KG |
| Year: |
2015 |
| Journal: |
Endocrine |
| Title: |
Autocrine effect of Zn?? on the glucose-stimulated insulin secretion. |
| Volume: |
50 |
| Issue: |
1 |
| Pages: |
110-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hern?ndez-S?nchez C |
| Year: |
1997 |
| Journal: |
Endocrinology |
| Title: |
Developmental and tissue-specific sulfonylurea receptor gene expression. |
| Volume: |
138 |
| Issue: |
2 |
| Pages: |
705-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nicholson JD |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
SUR1-Associated Mechanisms Are Not Involved in Ischemic Optic Neuropathy 1 Day Post-Injury. |
| Volume: |
11 |
| Issue: |
8 |
| Pages: |
e0148855 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gurzeler E |
| Year: |
2021 |
| Journal: |
PLoS One |
| Title: |
SUR1-E1506K mutation impairs glucose tolerance and promotes vulnerable atherosclerotic plaque phenotype in hypercholesterolemic mice. |
| Volume: |
16 |
| Issue: |
11 |
| Pages: |
e0258408 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sakamaki G |
| Year: |
2021 |
| Journal: |
Behav Brain Res |
| Title: |
Loss of SUR1 subtype K(ATP) channels alters antinociception and locomotor activity after opioid administration. |
| Volume: |
414 |
|
| Pages: |
113467 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zerangue N |
| Year: |
1999 |
| Journal: |
Neuron |
| Title: |
A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels. |
| Volume: |
22 |
| Issue: |
3 |
| Pages: |
537-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Reimann F |
| Year: |
1999 |
| Journal: |
J Physiol |
| Title: |
Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor. |
| Volume: |
518 ( Pt 2) |
| Issue: |
Pt 2 |
| Pages: |
325-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sakura H |
| Year: |
1999 |
| Journal: |
J Physiol |
| Title: |
Altered functional properties of KATP channel conferred by a novel splice variant of SUR1. |
| Volume: |
521 Pt 2 |
| Issue: |
Pt 2 |
| Pages: |
337-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tanizawa Y |
| Year: |
2000 |
| Journal: |
Diabetes |
| Title: |
Genetic analysis of Japanese patients with persistent hyperinsulinemic hypoglycemia of infancy: nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1. |
| Volume: |
49 |
| Issue: |
1 |
| Pages: |
114-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McKay NG |
| Year: |
2000 |
| Journal: |
Br J Pharmacol |
| Title: |
Sensitivity of Kir6.2-SUR1 currents, in the absence and presence of sodium azide, to the K(ATP) channel inhibitors, ciclazindol and englitazone. |
| Volume: |
130 |
| Issue: |
4 |
| Pages: |
857-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mikhailov MV |
| Year: |
2000 |
| Journal: |
FEBS Lett |
| Title: |
Investigation of the molecular assembly of beta-cell K(ATP) channels. |
| Volume: |
482 |
| Issue: |
1-2 |
| Pages: |
59-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Haller M |
| Year: |
2001 |
| Journal: |
J Physiol |
| Title: |
Dynamic activation of K(ATP) channels in rhythmically active neurons. |
| Volume: |
537 |
| Issue: |
Pt 1 |
| Pages: |
69-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mu??oz A |
| Year: |
2003 |
| Journal: |
Stroke |
| Title: |
Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels. |
| Volume: |
34 |
| Issue: |
1 |
| Pages: |
164-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Geng X |
| Year: |
2003 |
| Journal: |
Diabetes |
| Title: |
The insulin secretory granule is the major site of K(ATP) channels of the endocrine pancreas. |
| Volume: |
52 |
| Issue: |
3 |
| Pages: |
767-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lacza Z |
| Year: |
2003 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Heart mitochondria contain functional ATP-dependent K+ channels. |
| Volume: |
35 |
| Issue: |
11 |
| Pages: |
1339-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
D??fer M |
| Year: |
2004 |
| Journal: |
Diabetologia |
| Title: |
Oscillations of membrane potential and cytosolic Ca(2+) concentration in SUR1(-/-) beta cells. |
| Volume: |
47 |
| Issue: |
3 |
| Pages: |
488-498 |
|
•
•
•
•
•
|