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Search results 1 to 100 out of 323 for Abcg5

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
64240 | ABCG5
Type: gene
Organism: human
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Gene
100145776 | abcg5
Type: gene
Organism: frog, western clawed
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Gene
114628 | Abcg5
Type: gene
Organism: rat
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Gene
481354 | ABCG5
Type: gene
Organism: dog, domestic
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Gene
459190 | ABCG5
Type: gene
Organism: chimpanzee
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Gene
515536 | ABCG5
Type: gene
Organism: cattle
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Gene
421401 | ABCG5
Type: gene
Organism: chicken
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Gene
557317 | abcg5
Type: gene
Organism: zebrafish
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Gene
713610 | ABCG5
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1351659 | Abcg5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15930515 | J:100478
First Author: Yu L
Year: 2005
Journal: J Lipid Res
Title: Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8.
Volume: 46
Issue: 8
Pages: 1739-44
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Publication
18402465 | J:134560
First Author: Wang J
Year: 2008
Journal: Biochemistry
Title: Purification and reconstitution of sterol transfer by native mouse ABCG5 and ABCG8.
Volume: 47
Issue: 18
Pages: 5194-204
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Publication
12444248 | J:80679
First Author: Yu L
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion.
Volume: 99
Issue: 25
Pages: 16237-42
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Publication
12208868 | J:78963
First Author: Yu L
Year: 2002
Journal: J Clin Invest
Title: Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol.
Volume: 110
Issue: 5
Pages: 671-80
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Publication
14504269 | J:86723
First Author: Graf GA
Year: 2003
Journal: J Biol Chem
Title: ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion.
Volume: 278
Issue: 48
Pages: 48275-82
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Publication
15611112 | J:128570
First Author: Yu L
Year: 2005
Journal: J Biol Chem
Title: Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion.
Volume: 280
Issue: 10
Pages: 8742-7
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Publication
11907139 | J:75695
First Author: Lu K
Year: 2002
Journal: J Lipid Res
Title: Molecular cloning, genomic organization, genetic variations, and characterization of murine sterolin genes Abcg5 and Abcg8.
Volume: 43
Issue: 4
Pages: 565-78
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Publication
12208867 | J:248556
First Author: Graf GA
Year: 2002
Journal: J Clin Invest
Title: Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface.
Volume: 110
Issue: 5
Pages: 659-69
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Publication
22715101 | J:188929
First Author: Su K
Year: 2012
Journal: J Biol Chem
Title: The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation.
Volume: 287
Issue: 34
Pages: 28564-75
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Publication
16867993 | J:116923
First Author: Wang J
Year: 2006
Journal: J Biol Chem
Title: Sterol transfer by ABCG5 and ABCG8: in vitro assay and reconstitution.
Volume: 281
Issue: 38
Pages: 27894-904
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Publication
11901146 | J:76837
First Author: Repa JJ
Year: 2002
Journal: J Biol Chem
Title: Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.
Volume: 277
Issue: 21
Pages: 18793-800
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Publication
15102882 | J:90651
First Author: Duan LP
Year: 2004
Journal: J Lipid Res
Title: Cholesterol absorption is mainly regulated by the jejunal and ileal ATP-binding cassette sterol efflux transporters Abcg5 and Abcg8 in mice.
Volume: 45
Issue: 7
Pages: 1312-23
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Publication
11452359 | J:72524
First Author: Lu K
Year: 2001
Journal: Am J Hum Genet
Title: Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively.
Volume: 69
Issue: 2
Pages: 278-90
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Publication
40967386 | J:373839
First Author: Anspach GB
Year: 2025
Journal: J Lipid Res
Title: ABCG5/ABCG8-independent mechanisms fail to maintain sterol balance in mice fed a high-cholesterol diet.
Volume: 66
Issue: 10
Pages: 100902
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Publication
18509196 | J:139767
First Author: Calpe-Berdiel L
Year: 2008
Journal: J Lipid Res
Title: Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.
Volume: 49
Issue: 9
Pages: 1904-11
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Publication
14657202 | J:121052
First Author: Yu L
Year: 2004
Journal: J Lipid Res
Title: Selective sterol accumulation in ABCG5/ABCG8-deficient mice.
Volume: 45
Issue: 2
Pages: 301-7
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Publication
15372105 | J:92860
First Author: Yang C
Year: 2004
Journal: J Clin Invest
Title: Disruption of cholesterol homeostasis by plant sterols.
Volume: 114
Issue: 6
Pages: 813-22
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Publication
27014967 | J:285508
First Author: Wang HH
Year: 2016
Journal: Hepatology
Title: Evidence that the adenosine triphosphate-binding cassette G5/G8-independent pathway plays a determinant role in cholesterol gallstone formation in mice.
Volume: 64
Issue: 3
Pages: 853-64
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Publication
19846887 | J:157223
First Author: Chase TH
Year: 2010
Journal: Blood
Title: The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.
Volume: 115
Issue: 6
Pages: 1267-76
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Publication
25378657 | J:215443
First Author: Wang J
Year: 2015
Journal: J Lipid Res
Title: Relative roles of ABCG5/ABCG8 in liver and intestine.
Volume: 56
Issue: 2
Pages: 319-30
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Publication
23380580 | J:194476
First Author: McDaniel AL
Year: 2013
Journal: Am J Pathol
Title: Phytosterol feeding causes toxicity in ABCG5/G8 knockout mice.
Volume: 182
Issue: 4
Pages: 1131-8
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Publication
30675518 | J:278281
 
First Author: Tao C
Year: 2019
Journal: Commun Biol
Title: Stigmasterol accumulation causes cardiac injury and promotes mortality.
Volume: 2
Pages: 20
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Publication
21885848 | J:191459
First Author: Escol?-Gil JC
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: The cholesterol content of Western diets plays a major role in the paradoxical increase in high-density lipoprotein cholesterol and upregulates the macrophage reverse cholesterol transport pathway.
Volume: 31
Issue: 11
Pages: 2493-9
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Publication
17825296 | J:126835
First Author: Vrins C
Year: 2007
Journal: FEBS Lett
Title: The sterol transporting heterodimer ABCG5/ABCG8 requires bile salts to mediate cholesterol efflux.
Volume: 581
Issue: 24
Pages: 4616-20
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Publication
23129576 | J:260059
First Author: Wilson DW
Year: 2013
Journal: Toxicol Pathol
Title: Inflammatory dilated cardiomyopathy in Abcg5-deficient mice.
Volume: 41
Issue: 6
Pages: 880-92
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Publication
19416968 | J:152280
First Author: van der Veen JN
Year: 2009
Journal: J Biol Chem
Title: Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol.
Volume: 284
Issue: 29
Pages: 19211-9
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Publication
21315718 | J:192648
First Author: Yamanashi Y
Year: 2011
Journal: Gastroenterology
Title: NPC2 regulates biliary cholesterol secretion via stimulation of ABCG5/G8-mediated cholesterol transport.
Volume: 140
Issue: 5
Pages: 1664-74
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Publication
12150943 | J:77913
First Author: Remaley AT
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster.
Volume: 295
Issue: 2
Pages: 276-82
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Publication
18796403 | J:149007
First Author: Tang W
Year: 2009
Journal: J Lipid Res
Title: Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8.
Volume: 50
Issue: 2
Pages: 293-300
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Publication
34465831 | J:312902
First Author: Ge H
Year: 2021
Journal: Sci Rep
Title: Phytosterol accumulation results in ventricular arrhythmia, impaired cardiac function and death in mice.
Volume: 11
Issue: 1
Pages: 17449
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Publication
22669916 | J:186555
First Author: Nguyen TM
Year: 2012
Journal: J Lipid Res
Title: ACAT2 and ABCG5/G8 are both required for efficient cholesterol absorption in mice: evidence from thoracic lymph duct cannulation.
Volume: 53
Issue: 8
Pages: 1598-609
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Publication
16151694 | J:97424
First Author: Wittenburg H
Year: 2005
Journal: Mamm Genome
Title: Association of a lithogenic Abcg5/Abcg8 allele on Chromosome 17 (Lith9) with cholesterol gallstone formation in PERA/EiJ mice.
Volume: 16
Issue: 7
Pages: 495-504
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Publication
18156627 | J:133685
First Author: Kruit JK
Year: 2008
Journal: J Biol Chem
Title: Plant sterols cause macrothrombocytopenia in a mouse model of sitosterolemia.
Volume: 283
Issue: 10
Pages: 6281-7
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Publication
16857831 | J:114929
First Author: Pl?sch T
Year: 2006
Journal: J Nutr
Title: Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter.
Volume: 136
Issue: 8
Pages: 2135-40
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Publication
25552583 | J:224033
First Author: Gooijert KE
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: The mechanism of increased biliary lipid secretion in mice with genetic inactivation of bile salt export pump.
Volume: 308
Issue: 5
Pages: G450-7
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Publication
23180829 | J:192806
First Author: Solca C
Year: 2013
Journal: J Lipid Res
Title: Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolin-deficient mice.
Volume: 54
Issue: 2
Pages: 397-409
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Publication
31251986 | J:382655
First Author: Chen Y
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: FMO3 and its metabolite TMAO contribute to the formation of gallstones.
Volume: 1865
Issue: 10
Pages: 2576-2585
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Publication
18587407 | J:137829
First Author: Biddinger SB
Year: 2008
Journal: Nat Med
Title: Hepatic insulin resistance directly promotes formation of cholesterol gallstones.
Volume: 14
Issue: 7
Pages: 778-82
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Publication
31097214 | J:379920
First Author: M?ndez-Lara KA
Year: 2019
Journal: Clin Investig Arterioscler
Title: Vitamin B3 impairs reverse cholesterol transport in Apolipoprotein E-deficient mice.
Volume: 31
Issue: 6
Pages: 251-260
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Publication
14699507 | J:87209
First Author: Pl?sch T
Year: 2004
Journal: Gastroenterology
Title: Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.
Volume: 126
Issue: 1
Pages: 290-300
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Publication
23926302 | J:203271
First Author: Kanaji T
Year: 2013
Journal: Blood
Title: Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia.
Volume: 122
Issue: 15
Pages: 2732-42
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Publication
16685081 | J:112668
First Author: Wittenburg H
Year: 2006
Journal: J Lipid Res
Title: QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains.
Volume: 47
Issue: 8
Pages: 1780-90
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Publication
15040800 | J:94759
 
First Author: Klett EL
Year: 2004
Journal: BMC Med
Title: A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol.
Volume: 2
Pages: 5
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Publication
12949731 | J:84582
First Author: Wittenburg H
Year: 2003
Journal: Gastroenterology
Title: FXR and ABCG5/ABCG8 as determinants of cholesterol gallstone formation from quantitative trait locus mapping in mice.
Volume: 125
Issue: 3
Pages: 868-81
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Publication
19416652 | J:148766
First Author: Li Z
Year: 2009
Journal: Biochim Biophys Acta
Title: Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol.
Volume: 1791
Issue: 4
Pages: 297-306
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Publication
15075252 | J:96078
First Author: Wang HH
Year: 2004
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1-/- mice.
Volume: 287
Issue: 3
Pages: G547-54
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Publication
14872007 | J:89282
First Author: Lyons MA
Year: 2004
Journal: Physiol Genomics
Title: Genetic contributors to lipoprotein cholesterol levels in an intercross of 129S1/SvImJ and RIIIS/J inbred mice.
Volume: 17
Issue: 2
Pages: 114-21
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Publication
16614371 | J:112995
First Author: Pl?sch T
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice.
Volume: 291
Issue: 3
Pages: G414-23
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Publication
30611276 | J:295676
First Author: Ibold B
Year: 2019
Journal: Lipids Health Dis
Title: Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues.
Volume: 18
Issue: 1
Pages: 2
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Publication
29599133 | J:285128
First Author: Bowden KL
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In Vivo.
Volume: 38
Issue: 5
Pages: 1191-1201
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Publication
29853564 | J:373751
First Author: Molusky MM
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Metformin and AMP Kinase Activation Increase Expression of the Sterol Transporters ABCG5/8 (ATP-Binding Cassette Transporter G5/G8) With Potential Antiatherogenic Consequences.
Volume: 38
Issue: 7
Pages: 1493-1503
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Protein Coding Gene
MGP_CAROLIEiJ_G0021925 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
ENSMUSG00200023496 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195028586 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220013567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180024113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175006540 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1351659 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215009481 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005011613 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210019671 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185019702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205006034 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230008669 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000010759 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190009551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225030275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010005367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005020744 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020915 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
ENSMSPG00010008581 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
21738715 | J:174764
First Author: Brufau G
Year: 2011
Journal: PLoS One
Title: A reappraisal of the mechanism by which plant sterols promote neutral sterol loss in mice.
Volume: 6
Issue: 6
Pages: e21576
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:7560652
Age: embryonic day 17.5
Specimen Label: -2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7560652
Age: postnatal day 0
Specimen Label: 0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7560652
Age: postnatal day 1
Specimen Label: 1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7560652
Age: postnatal day 3
Specimen Label: 3
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560652
Age: postnatal day 5
Specimen Label: 5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560652
Age: postnatal day 10
Specimen Label: 10
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560652
Age: postnatal day 15
Specimen Label: 15
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560652
Age: postnatal day 20
Specimen Label: 20
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560652
Age: postnatal day 25
Specimen Label: 25
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560652
Age: postnatal day 30
Specimen Label: 30
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560652
Age: postnatal day 30
Specimen Label: 45
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:7550676
Assay Type: RT-PCR
Annotation Date: 2023-11-27
Strength: Present
Sex: Male
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7560652
Age: postnatal day 60
Specimen Label: 60
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:4422996
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5422089
Age: embryonic day 14.5
Specimen Label: EB1734; Specimen B610
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4422996
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5422089
Age: embryonic day 14.5
Specimen Label: EB1734; Specimen B610
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4422996
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5422089
Age: embryonic day 14.5
Specimen Label: EB1734; Specimen B610
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4422996
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5422089
Age: embryonic day 14.5
Specimen Label: EB1734; Specimen B610
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4422996
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5422089
Age: embryonic day 14.5
Specimen Label: EB1734; Specimen B610
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4422996
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5422089
Age: embryonic day 14.5
Specimen Label: EB1734; Specimen B610
Detected: false
Specimen Num: 1
•
•
•
•
•




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