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Search results 1 to 91 out of 91 for Abhd12

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Hits by Category

Type Details Score
Gene
26090 | ABHD12
Type: gene
Organism: human
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Gene
744997 | ABHD12
Type: gene
Organism: chimpanzee
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Gene
768242 | ABHD12
Type: gene
Organism: cattle
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Gene
421249 | ABHD12
Type: gene
Organism: chicken
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Gene
767657 | abhd12
Type: gene
Organism: zebrafish
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Gene
705915 | ABHD12
Type: gene
Organism: macaque, rhesus
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Gene
100216158 | abhd12
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR026605 | ABHD12
Type: Family
Description: ABHD12 (also known as the abhydrolase domain-containing protein 12) is a lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes [, ]. In humans, defects in ABHD12 are the cause of polyneuropathy hearing loss ataxia retinitis pigmentosa and cataract (PHARC). PHARC is a slowly progressive neurologic disorder [].
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Gene
499913 | Abhd12
Type: gene
Organism: rat
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Gene
477004 | ABHD12
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1923442 | Abhd12
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30237167 | J:272811
First Author: Joshi A
Year: 2018
Journal: J Biol Chem
Title: Biochemical characterization of the PHARC-associated serine hydrolase ABHD12 reveals its preference for very-long-chain lipids.
Volume: 293
Issue: 44
Pages: 16953-16963
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Publication
23297193 | J:193716
First Author: Blankman JL
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC.
Volume: 110
Issue: 4
Pages: 1500-5
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Protein
D6RFU2
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Protein
Q99LR1
Organism: Mus musculus/domesticus
Length: 398  
Fragment?: false
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Publication
20797687 | -
First Author: Fiskerstrand T
Year: 2010
Journal: Am J Hum Genet
Title: Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism.
Volume: 87
Issue: 3
Pages: 410-7
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Publication
30643283 | J:273578
First Author: Kelkar DS
Year: 2019
Journal: Nat Chem Biol
Title: A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase.
Volume: 15
Issue: 2
Pages: 169-178
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Publication
25580854 | J:232688
First Author: Kamat SS
Year: 2015
Journal: Nat Chem Biol
Title: Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay.
Volume: 11
Issue: 2
Pages: 164-71
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Publication
31213981 | J:313112
 
First Author: Leishman E
Year: 2019
Journal: Front Mol Neurosci
Title: Elevated Levels of Arachidonic Acid-Derived Lipids Including Prostaglandins and Endocannabinoids Are Present Throughout ABHD12 Knockout Brains: Novel Insights Into the Neurodegenerative Phenotype.
Volume: 12
Pages: 142
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Publication
18096503 | J:217994
First Author: Blankman JL
Year: 2007
Journal: Chem Biol
Title: A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol.
Volume: 14
Issue: 12
Pages: 1347-56
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Gene
108698773 | LOC108698773
Type: gene
Organism: frog, African clawed
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Publication
32462874 | J:304879
First Author: Singh S
Year: 2020
Journal: Biochemistry
Title: Mapping the Neuroanatomy of ABHD16A, ABHD12, and Lysophosphatidylserines Provides New Insights into the Pathophysiology of the Human Neurological Disorder PHARC.
Volume: 59
Issue: 24
Pages: 2299-2311
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Protein Coding Gene
MGP_CAROLIEiJ_G0024429 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026632 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026599 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026570 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1923442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027057 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026465 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026430 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026569 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027112 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025885 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025872 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025349 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
26779719 | J:229982
 
First Author: Viader A
Year: 2016
Journal: Elife
Title: A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation.
Volume: 5
Pages: e12345
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Publication
27307232 | J:248443
First Author: Yokoi N
Year: 2016
Journal: J Neurosci
Title: Identification of PSD-95 Depalmitoylating Enzymes.
Volume: 36
Issue: 24
Pages: 6431-44
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Publication
23806692 | J:205325
First Author: Siegmund SV
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Fatty acid amide hydrolase but not monoacyl glycerol lipase controls cell death induced by the endocannabinoid 2-arachidonoyl glycerol in hepatic cell populations.
Volume: 437
Issue: 1
Pages: 48-54
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Publication
25871848 | J:229253
 
First Author: Spies N
Year: 2015
Journal: Elife
Title: Constraint and divergence of global gene expression in the mammalian embryo.
Volume: 4
Pages: e05538
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Publication
22632720 | J:188364
First Author: Schwenk J
Year: 2012
Journal: Neuron
Title: High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.
Volume: 74
Issue: 4
Pages: 621-33
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Publication
15010206 | J:88423
First Author: García-Frigola C
Year: 2004
Journal: Brain Res Mol Brain Res
Title: A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.
Volume: 122
Issue: 2
Pages: 133-50
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q99LR1-2
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 1
Description: Lysophosphatidylserine lipase ABHD12
Type: chain
End: 398
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Publication
30420694 | -
First Author: Ogasawara D
Year: 2018
Journal: Nat Chem Biol
Title: Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo.
Volume: 14
Issue: 12
Pages: 1099-1108
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Protein
D6RI21
Organism: Mus musculus/domesticus
Length: 70  
Fragment?: false
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Protein
F7BHM8
Organism: Mus musculus/domesticus
Length: 56  
Fragment?: true
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Allele
Abhd12<em1Smoc> | MGI:7288048
Name: abhydrolase domain containing 12; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
20657592 | J:163762
First Author: Marrs WR
Year: 2010
Journal: Nat Neurosci
Title: The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.
Volume: 13
Issue: 8
Pages: 951-7
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Publication
36891866 | J:335550
 
First Author: Bennett TM
Year: 2023
Journal: G3 (Bethesda)
Title: Whole-exome sequencing prioritizes candidate genes for hereditary cataract in the Emory mouse mutant.
Volume: 13
Issue: 5
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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