|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 303 for Abi1

<< First    < Previous  |  Next >    Last >>
0.058s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: Abl-interactor (Abi) proteins are targets of Abl-family nonreceptor tyrosine kinases and are required for cytoskeletal reorganization []. Abi1 and Abi2 play an important role in actin cytoskeleton dynamics through participation in several multiprotein complexes. They participate in the formation of the Abi/WAVE complex, which regulates Arp2/3-mediated actin filament nucleation and actin network assembly [, , ].Abi1 promotes tyrosine phosphorylation of mammalian enabled (Mena) by c-Abl kinase []. It is essential for WAVE2 complex integrity and embryonic survival in mice []. Abi1 and the p85 regulatory subunit of PI-3 kinase may be the link between actin cytoskeleton remodelling and growth receptor signalling [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Dubielecka PM
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Essential role for Abi1 in embryonic survival and WAVE2 complex integrity.
Volume: 108
Issue: 17
Pages: 7022-7
Protein
Organism: Mus musculus/domesticus
Length: 450  
Fragment?: false
Publication
First Author: Tani K
Year: 2003
Journal: J Biol Chem
Title: Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase.
Volume: 278
Issue: 24
Pages: 21685-92
Publication
First Author: Hirao N
Year: 2006
Journal: FEBS Lett
Title: NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation.
Volume: 580
Issue: 27
Pages: 6464-70
Publication  
First Author: Qi Y
Year: 2020
Journal: J Cell Biol
Title: PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.
Volume: 219
Issue: 9
Publication
First Author: Wang R
Year: 2022
Journal: iScience
Title: Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling.
Volume: 25
Issue: 2
Pages: 103833
Publication
First Author: Kotula L
Year: 2012
Journal: FEBS Lett
Title: Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling.
Volume: 586
Issue: 17
Pages: 2790-4
Publication
First Author: Chorzalska A
Year: 2018
Journal: Blood
Title: Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis.
Volume: 132
Issue: 19
Pages: 2053-2066
Publication
First Author: Stradal T
Year: 2001
Journal: Curr Biol
Title: The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia.
Volume: 11
Issue: 11
Pages: 891-5
Protein
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 475  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 393  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 451  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 422  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
Publication
First Author: Ring C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.
Volume: 108
Issue: 1
Pages: 149-54
Publication  
First Author: Xiong X
Year: 2012
Journal: Oncogenesis
Title: Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice.
Volume: 1
Pages: e26
Publication
First Author: Menna E
Year: 2009
Journal: PLoS Biol
Title: Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF).
Volume: 7
Issue: 6
Pages: e1000138
Publication
First Author: Cohen J
Year: 2019
Journal: J Cell Biol
Title: The Wave complex controls epidermal morphogenesis and proliferation by suppressing Wnt-Sox9 signaling.
Volume: 218
Issue: 4
Pages: 1390-1406
Publication
First Author: Yang C
Year: 2007
Journal: PLoS Biol
Title: Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells.
Volume: 5
Issue: 11
Pages: e317
Publication
First Author: Eto K
Year: 2007
Journal: Blood
Title: The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery.
Volume: 110
Issue: 10
Pages: 3637-47
Publication
First Author: Disanza A
Year: 2004
Journal: Nat Cell Biol
Title: Eps8 controls actin-based motility by capping the barbed ends of actin filaments.
Volume: 6
Issue: 12
Pages: 1180-8
Publication
First Author: Abou-Kheir W
Year: 2008
Journal: J Cell Sci
Title: Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.
Volume: 121
Issue: Pt 3
Pages: 379-90
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Chen S
Year: 2008
Journal: J Mol Biol
Title: Tyrosine phosphorylation in the SH3 domain disrupts negative regulatory interactions within the c-Abl kinase core.
Volume: 383
Issue: 2
Pages: 414-23
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1742828
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 26
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 27
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 28
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1788628
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 29
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1789128
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 30
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1885228
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 31
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1866628
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 32
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 33
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 34
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3515128
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 35
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3528528
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 36
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 37
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 38
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 39
GXD Expression    
Probe: MGI:1204993
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1204995
Age: postnatal week 6-8
Image: st96_354
Specimen Label: None
Detected: true
Specimen Num: 40