Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
Homo sapiens |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Rattus norvegicus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Danio rerio |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
ABL tyrosine kinases are nonreceptor tyrosine kinases containing an SH3-SH2-TK (Src homology 3-Src homology 2-tyrosine kinase) domain cassette, which confers autoregulated kinase activity. This cassette is coupled to an actin-binding and -bundling domain, which makes ABL proteins capable of connecting phosphoregulation with actin-filament reorganization. Two vertebrate ABL tyrosine kinases have been identified, ABL1 and ABL2 [].A downstream effector of RAS, RIN1, have been found to bind to the SH3 and SH2 domains of ABL1/ABL2 to relieve autoinhibition and regulate their activity [].This entry includes animal ABL1 and viral oncogene products that are homologous to ABL1 []. ABL1 plays a role in many key processes linked to cell growth and survival such as cytoskeleton remodelling in response to extracellular stimuli, cell motility and adhesion, receptor endocytosis, autophagy, DNA damage response and apoptosis [, , , ]. Normal ABL1 can serve as a tumour suppressor and therapeutic target in leukemias expressing oncogenic forms of the kinase []. |
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•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus |
Length: |
1123
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Dasgupta Y |
Year: |
2016 |
Journal: |
Blood |
Title: |
Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases. |
Volume: |
127 |
Issue: |
17 |
Pages: |
2131-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Colicelli J |
Year: |
2010 |
Journal: |
Sci Signal |
Title: |
ABL tyrosine kinases: evolution of function, regulation, and specificity. |
Volume: |
3 |
Issue: |
139 |
Pages: |
re6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bueno MJ |
Year: |
2008 |
Journal: |
Cancer Cell |
Title: |
Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression. |
Volume: |
13 |
Issue: |
6 |
Pages: |
496-506 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao X |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms. |
Volume: |
283 |
Issue: |
46 |
Pages: |
31401-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yogalingam G |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components. |
Volume: |
283 |
Issue: |
51 |
Pages: |
35941-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Groffen J |
Year: |
1983 |
Journal: |
Nature |
Title: |
Homology between phosphotyrosine acceptor site of human c-abl and viral oncogene products. |
Volume: |
304 |
Issue: |
5922 |
Pages: |
167-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sossey-Alaoui K |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration. |
Volume: |
282 |
Issue: |
36 |
Pages: |
26257-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanos B |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Abl tyrosine kinase regulates endocytosis of the epidermal growth factor receptor. |
Volume: |
281 |
Issue: |
43 |
Pages: |
32714-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Virgili A |
Year: |
2011 |
Journal: |
Cancer Res |
Title: |
Imatinib sensitivity in BCR-ABL1-positive chronic myeloid leukemia cells is regulated by the remaining normal ABL1 allele. |
Volume: |
71 |
Issue: |
16 |
Pages: |
5381-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim DH |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARγ2. |
Volume: |
17 |
Issue: |
6 |
Pages: |
1671-1682 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JY |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Timely Inhibitory Circuit Formation Controlled by Abl1 Regulates Innate Olfactory Behaviors in Mouse. |
Volume: |
30 |
Issue: |
1 |
Pages: |
187-201.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshida K |
Year: |
2002 |
Journal: |
Mol Cell Biol |
Title: |
c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage. |
Volume: |
22 |
Issue: |
10 |
Pages: |
3292-300 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raimondi C |
Year: |
2014 |
Journal: |
J Exp Med |
Title: |
Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells. |
Volume: |
211 |
Issue: |
6 |
Pages: |
1167-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zukerberg LR |
Year: |
2000 |
Journal: |
Neuron |
Title: |
Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. |
Volume: |
26 |
Issue: |
3 |
Pages: |
633-46 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus |
Length: |
1142
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Oppi C |
Year: |
1987 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Nucleotide sequence of testis-derived c-abl cDNAs: implications for testis-specific transcription and abl oncogene activation. |
Volume: |
84 |
Issue: |
23 |
Pages: |
8200-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang JY |
Year: |
1984 |
Journal: |
Cell |
Title: |
The mouse c-abl locus: molecular cloning and characterization. |
Volume: |
36 |
Issue: |
2 |
Pages: |
349-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernards A |
Year: |
1988 |
Journal: |
Oncogene |
Title: |
Four murine c-abl mRNAs arise by usage of two transcriptional promoters and alternative splicing. |
Volume: |
2 |
Issue: |
4 |
Pages: |
297-304 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tybulewicz VL |
Year: |
1991 |
Journal: |
Cell |
Title: |
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. |
Volume: |
65 |
Issue: |
7 |
Pages: |
1153-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schwartzberg PL |
Year: |
1991 |
Journal: |
Cell |
Title: |
Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations. |
Volume: |
65 |
Issue: |
7 |
Pages: |
1165-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanis KQ |
Year: |
2003 |
Journal: |
Mol Cell Biol |
Title: |
Two distinct phosphorylation pathways have additive effects on Abl family kinase activation. |
Volume: |
23 |
Issue: |
11 |
Pages: |
3884-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kain KH |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes. |
Volume: |
276 |
Issue: |
19 |
Pages: |
16185-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taagepera S |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase. |
Volume: |
95 |
Issue: |
13 |
Pages: |
7457-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cong F |
Year: |
2000 |
Journal: |
Mol Cell |
Title: |
Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation. |
Volume: |
6 |
Issue: |
6 |
Pages: |
1413-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato H |
Year: |
2002 |
Journal: |
Biochim Biophys Acta |
Title: |
ik3-2, a relative to ik3-1/cables, is associated with cdk3, cdk5, and c-abl. |
Volume: |
1574 |
Issue: |
2 |
Pages: |
157-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrano N |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene. |
Volume: |
276 |
Issue: |
23 |
Pages: |
19787-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kharbanda S |
Year: |
1997 |
Journal: |
Nature |
Title: |
Functional interaction between DNA-PK and c-Abl in response to DNA damage. |
Volume: |
386 |
Issue: |
6626 |
Pages: |
732-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen A |
Year: |
2011 |
Journal: |
Mol Cell Biol |
Title: |
c-Abl-mediated tyrosine phosphorylation of the T-bet DNA-binding domain regulates CD4+ T-cell differentiation and allergic lung inflammation. |
Volume: |
31 |
Issue: |
16 |
Pages: |
3445-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Plattner R |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor. |
Volume: |
24 |
Issue: |
6 |
Pages: |
2573-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hardin JD |
Year: |
1996 |
Journal: |
Oncogene |
Title: |
Transgenes encoding both type I and type IV c-abl proteins rescue the lethality of c-abl mutant mice. |
Volume: |
12 |
Issue: |
12 |
Pages: |
2669-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Preyer M |
Year: |
2007 |
Journal: |
Cell Death Differ |
Title: |
Delayed activation of Bax by DNA damage in embryonic stem cells with knock-in mutations of the Abl nuclear localization signals. |
Volume: |
14 |
Issue: |
6 |
Pages: |
1139-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Finn AJ |
Year: |
2003 |
Journal: |
Nat Neurosci |
Title: |
Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. |
Volume: |
6 |
Issue: |
7 |
Pages: |
717-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khatri A |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia. |
Volume: |
116 |
Issue: |
5 |
Pages: |
1603-1612 |
|
•
•
•
•
•
|
Publication |
First Author: |
Singh J |
Year: |
2010 |
Journal: |
Genes Dev |
Title: |
Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation. |
Volume: |
24 |
Issue: |
19 |
Pages: |
2157-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsuji K |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Differential effect of ik3-1/cables on p53- and p73-induced cell death. |
Volume: |
277 |
Issue: |
4 |
Pages: |
2951-7 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus musculus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Raina D |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. |
Volume: |
280 |
Issue: |
12 |
Pages: |
11147-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brahmachari S |
Year: |
2016 |
Journal: |
J Clin Invest |
Title: |
Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration. |
Volume: |
126 |
Issue: |
8 |
Pages: |
2970-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Symons RC |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Multiple genetic loci modify susceptibility to plasmacytoma-related morbidity in E(mu)-v-abl transgenic mice. |
Volume: |
99 |
Issue: |
17 |
Pages: |
11299-304 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cleary RA |
Year: |
2013 |
Journal: |
Respir Res |
Title: |
Role of Abl in airway hyperresponsiveness and airway remodeling. |
Volume: |
14 |
|
Pages: |
105 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu R |
Year: |
2017 |
Journal: |
Diabetologia |
Title: |
c-Abl inhibition mitigates diet-induced obesity through improving insulin sensitivity of subcutaneous fat in mice. |
Volume: |
60 |
Issue: |
5 |
Pages: |
900-910 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu H |
Year: |
2018 |
Journal: |
Biochim Biophys Acta Mol Cell Res |
Title: |
The nonreceptor tyrosine kinase c-Abl phosphorylates Runx1 and regulates Runx1-mediated megakaryocyte maturation. |
Volume: |
1865 |
Issue: |
8 |
Pages: |
1060-1072 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schwartzberg PL |
Year: |
1989 |
Journal: |
Science |
Title: |
Germ-line transmission of a c-abl mutation produced by targeted gene disruption in ES cells. |
Volume: |
246 |
Issue: |
4931 |
Pages: |
799-803 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosenbaum H |
Year: |
1990 |
Journal: |
EMBO J |
Title: |
An E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene. |
Volume: |
9 |
Issue: |
3 |
Pages: |
897-905 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hardin JD |
Year: |
1996 |
Journal: |
Cell Immunol |
Title: |
Abnormal peripheral lymphocyte function in c-abl mutant mice. |
Volume: |
172 |
Issue: |
1 |
Pages: |
100-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schwartzberg PL |
Year: |
1990 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Targeted gene disruption of the endogenous c-abl locus by homologous recombination with DNA encoding a selectable fusion protein. |
Volume: |
87 |
Issue: |
8 |
Pages: |
3210-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lam QL |
Year: |
2007 |
Journal: |
Int Immunol |
Title: |
Impaired V(D)J recombination and increased apoptosis among B cell precursors in the bone marrow of c-Abl-deficient mice. |
Volume: |
19 |
Issue: |
3 |
Pages: |
267-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li B |
Year: |
2000 |
Journal: |
Nat Genet |
Title: |
Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation. |
Volume: |
24 |
Issue: |
3 |
Pages: |
304-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zipfel PA |
Year: |
2000 |
Journal: |
J Immunol |
Title: |
The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19. |
Volume: |
165 |
Issue: |
12 |
Pages: |
6872-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nunes I |
Year: |
2001 |
Journal: |
J Exp Med |
Title: |
c-abl is required for the development of hyperoxia-induced retinopathy. |
Volume: |
193 |
Issue: |
12 |
Pages: |
1383-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kharbanda S |
Year: |
1998 |
Journal: |
Oncogene |
Title: |
Functional role for the c-Abl tyrosine kinase in meiosis I. |
Volume: |
16 |
Issue: |
14 |
Pages: |
1773-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang X |
Year: |
2011 |
Journal: |
Cell Death Differ |
Title: |
A positive role for c-Abl in Atm and Atr activation in DNA damage response. |
Volume: |
18 |
Issue: |
1 |
Pages: |
5-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Imam SZ |
Year: |
2007 |
Journal: |
Nucleic Acids Res |
Title: |
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase. |
Volume: |
35 |
Issue: |
15 |
Pages: |
4941-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu HH |
Year: |
2001 |
Journal: |
Oncogene |
Title: |
Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor. |
Volume: |
20 |
Issue: |
30 |
Pages: |
3995-4006 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun J |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1. |
Volume: |
276 |
Issue: |
31 |
Pages: |
28984-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato M |
Year: |
2011 |
Journal: |
FEBS Lett |
Title: |
Identification and functional analysis of a new phosphorylation site (Y398) in the SH3 domain of Abi-1. |
Volume: |
585 |
Issue: |
6 |
Pages: |
834-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Escalante M |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Phosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesis. |
Volume: |
275 |
Issue: |
32 |
Pages: |
24787-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Risser R |
Year: |
1978 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Abelson antigen: a viral tumor antigen that is also a differentiation antigen of BALB/c mice. |
Volume: |
75 |
Issue: |
8 |
Pages: |
3918-22 |
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Publication |
First Author: |
Van de Ven WJ |
Year: |
1980 |
Journal: |
Virology |
Title: |
The nonstructural components of polyproteins encoded by replication-defective mammalian transforming retroviruses are phosphorylated and have associated protein kinase activity. |
Volume: |
101 |
Issue: |
1 |
Pages: |
185-97 |
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Publication |
First Author: |
Goff SP |
Year: |
1980 |
Journal: |
Cell |
Title: |
Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: studies with cloned viral DNA. |
Volume: |
22 |
Issue: |
3 |
Pages: |
777-85 |
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Publication |
First Author: |
Heisterkamp N |
Year: |
1982 |
Journal: |
Nature |
Title: |
Chromosomal localization of human cellular homologues of two viral oncogenes. |
Volume: |
299 |
Issue: |
5885 |
Pages: |
747-9 |
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Publication |
First Author: |
Goff SP |
Year: |
1982 |
Journal: |
Science |
Title: |
Chromosomal assignment of the endogenous proto-oncogene C-abl. |
Volume: |
218 |
Issue: |
4579 |
Pages: |
1317-9 |
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Publication |
First Author: |
Wang JY |
Year: |
1983 |
Journal: |
Mol Cell Biol |
Title: |
Cellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence. |
Volume: |
3 |
Issue: |
5 |
Pages: |
773-9 |
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Publication |
First Author: |
Ponzetto C |
Year: |
1985 |
Journal: |
Mol Cell Biol |
Title: |
Haploid expression of a unique c-abl transcript in the mouse male germ line. |
Volume: |
5 |
Issue: |
7 |
Pages: |
1791-4 |
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Publication |
First Author: |
Ben-Neriah Y |
Year: |
1986 |
Journal: |
Cell |
Title: |
Alternative 5' exons in c-abl mRNA. |
Volume: |
44 |
Issue: |
4 |
Pages: |
577-86 |
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Publication |
First Author: |
Meijer D |
Year: |
1987 |
Journal: |
EMBO J |
Title: |
Molecular characterization of the testis specific c-abl mRNA in mouse. |
Volume: |
6 |
Issue: |
13 |
Pages: |
4041-8 |
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Publication |
First Author: |
Trakhtenbrot L |
Year: |
1990 |
Journal: |
Leukemia |
Title: |
Chromosomal mapping of the murine c-abl proto-oncogene by in situ hybridization. |
Volume: |
4 |
Issue: |
2 |
Pages: |
136-7 |
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Publication |
First Author: |
Shore SK |
Year: |
1990 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Activation of murine c-abl protooncogene: effect of a point mutation on oncogenic activation. |
Volume: |
87 |
Issue: |
17 |
Pages: |
6502-6 |
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Publication |
First Author: |
Bazzoni G |
Year: |
1996 |
Journal: |
J Clin Invest |
Title: |
Bcr/Abl expression stimulates integrin function in hematopoietic cell lines. |
Volume: |
98 |
Issue: |
2 |
Pages: |
521-8 |
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Publication |
First Author: |
Dale B |
Year: |
1981 |
Journal: |
Mol Cell Biol |
Title: |
Characterization of mouse cellular deoxyribonucleic acid homologous to Abelson murine leukemia virus-specific sequences. |
Volume: |
1 |
Issue: |
8 |
Pages: |
731-42 |
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Publication |
First Author: |
Van Etten RA |
Year: |
1999 |
Journal: |
Trends Cell Biol |
Title: |
Cycling, stressed-out and nervous: cellular functions of c-Abl. |
Volume: |
9 |
Issue: |
5 |
Pages: |
179-86 |
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Publication |
First Author: |
Zou X |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Signaling pathways activated by oncogenic forms of Abl tyrosine kinase. |
Volume: |
274 |
Issue: |
26 |
Pages: |
18141-4 |
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Publication |
First Author: |
Jia DY |
Year: |
2008 |
Journal: |
J Neurochem |
Title: |
c-Abl is involved in high glucose-induced apoptosis in embryonic E12.5 cortical neural progenitor cells from the mouse brain. |
Volume: |
106 |
Issue: |
4 |
Pages: |
1720-30 |
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Publication |
First Author: |
Li X |
Year: |
2010 |
Journal: |
Cell Death Differ |
Title: |
c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3. |
Volume: |
17 |
Issue: |
8 |
Pages: |
1277-87 |
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Publication |
First Author: |
Mahul-Mellier AL |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease. |
Volume: |
23 |
Issue: |
11 |
Pages: |
2858-79 |
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GXD Expression |
Probe: |
MGI:5297826 |
Assay Type: |
Northern blot |
Annotation Date: |
2011-12-09 |
Strength: |
Not Specified |
Sex: |
Male |
Emaps: |
EMAPS:3570728 |
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Stage: |
TS28 |
Assay Id: |
MGI:5297842 |
Age: |
postnatal adult |
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Specimen Num: |
1 |
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