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Search results 1 to 67 out of 67 for Ace3

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
498012 | Ace3
Type: gene
Organism: rat
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Gene
100295485 | ACE3
Type: gene
Organism: cattle
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Protein Coding Gene
MGI:3644400 | Ace3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17597519 | J:123156
 
First Author: Rella M
Year: 2007
Journal: BMC Genomics
Title: Identification and characterisation of the angiotensin converting enzyme-3 (ACE3) gene: a novel mammalian homologue of ACE.
Volume: 8
Pages: 194
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Publication
20421979 | J:160139
First Author: Inoue N
Year: 2010
Journal: PLoS One
Title: Identification and disruption of sperm-specific angiotensin converting enzyme-3 (ACE3) in mouse.
Volume: 5
Issue: 4
Pages: e10301
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Publication
26892527 | J:259638
 
First Author: Yu CJ
Year: 2016
Journal: J Am Heart Assoc
Title: Angiotensin-Converting Enzyme 3 (ACE3) Protects Against Pressure Overload-Induced Cardiac Hypertrophy.
Volume: 5
Issue: 2
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Gene
100856208 | LOC100856208
Type: gene
Organism: dog, domestic
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Gene
107969298 | LOC107969298
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGP_CAROLIEiJ_G0017306 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019257 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019231 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3644400 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019681 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018593 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019009 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019121 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019112 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019142 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019718 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018358 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018644 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018435 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018149 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
19880118 | J:286877
First Author: Weiss D
Year: 2010
Journal: Atherosclerosis
Title: Vascular wall ACE is not required for atherogenesis in ApoE(-/-) mice.
Volume: 209
Issue: 2
Pages: 352-8
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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UniProt Feature
UniProt Feature
Begin: 24
Description: Angiotensin-converting enzyme-like protein Ace3
Type: chain
End: 737
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Protein
D0G895
Organism: Mus musculus/domesticus
Length: 737  
Fragment?: false
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Protein
P09470
Organism: Mus musculus/domesticus
Length: 1312  
Fragment?: false
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Protein
Q8R0I0
Organism: Mus musculus/domesticus
Length: 805  
Fragment?: false
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Protein
Q3U3Q7
Organism: Mus musculus/domesticus
Length: 1312  
Fragment?: false
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Protein
F6QCP8
Organism: Mus musculus/domesticus
Length: 1016  
Fragment?: true
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Protein
Q9D836
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: true
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Protein
F6X479
Organism: Mus musculus/domesticus
Length: 521  
Fragment?: true
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Protein
Q7TSV8
Organism: Mus musculus/domesticus
Length: 275  
Fragment?: true
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Protein
Q8K233
Organism: Mus musculus/domesticus
Length: 1015  
Fragment?: true
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Protein
Q3UXR1
Organism: Mus musculus/domesticus
Length: 557  
Fragment?: true
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Protein
Q5XK22
Organism: Mus musculus/domesticus
Length: 1187  
Fragment?: true
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Protein
C7ECU2
Organism: Mus musculus/domesticus
Length: 787  
Fragment?: true
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Protein
Q61265
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
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Protein
Q3TU20
Organism: Mus musculus/domesticus
Length: 1312  
Fragment?: false
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Protein
Q3URC9
Organism: Mus musculus/domesticus
Length: 805  
Fragment?: false
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Publication
9629165 | -
 
First Author: Isaac RE
Year: 1998
Journal: Ann N Y Acad Sci
Title: Toward a role for angiotensin-converting enzyme in insects.
Volume: 839
Pages: 288-92
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Publication
1851160 | -
First Author: Wei L
Year: 1991
Journal: J Biol Chem
Title: The two homologous domains of human angiotensin I-converting enzyme are both catalytically active.
Volume: 266
Issue: 14
Pages: 9002-8
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Publication
12633854 | -
First Author: Kim HM
Year: 2003
Journal: FEBS Lett
Title: Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril.
Volume: 538
Issue: 1-3
Pages: 65-70
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Publication
14754895 | -
First Author: Towler P
Year: 2004
Journal: J Biol Chem
Title: ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
Volume: 279
Issue: 17
Pages: 17996-8007
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Publication
17439247 | -
First Author: Corradi HR
Year: 2007
Journal: Biochemistry
Title: The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380.
Volume: 46
Issue: 18
Pages: 5473-8
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Publication
18457420 | -
First Author: Watermeyer JM
Year: 2008
Journal: Biochemistry
Title: Probing the basis of domain-dependent inhibition using novel ketone inhibitors of Angiotensin-converting enzyme.
Volume: 47
Issue: 22
Pages: 5942-50
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Publication
17464936 | -
First Author: Hamming I
Year: 2007
Journal: J Pathol
Title: The emerging role of ACE2 in physiology and disease.
Volume: 212
Issue: 1
Pages: 1-11
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Protein Domain
IPR001548 | Peptidase_M2
Type: Family
Description: This group of metallopeptidases belong to the MEROPS peptidase family M2 (clan MA(E)). The protein fold of the peptidase domain for members of this family resembles that of thermolysin, the type example for clan MA. The catalytic residues and zinc ligands have been identified, the zinc ion being ligated to two His residues within the motif HEXXH, showing that the enzyme belongs to the glu-zincin sub-group of metalloproteases [].Peptidyl-dipeptidase A (angiotensin-converting enzyme or ACE, ) is a mammalian enzyme responsible for cleavage of dipeptides from the C-termini of proteins, notably converting decapeptide angiotensin I to the octapeptide angiotensin II []. The enzyme exists in two differentially transcribed forms, the most common of which is from lung endothelium; this contains two homologous domains that have arisen by gene duplication []. The testis-specific form contains only the C-terminal domain, arising from a duplicated promoter region present in intron 12 of the gene []. Both enzymatic forms are membrane proteins that are anchored by means of a C-terminal transmembrane domain. Both domains of the endothelial enzyme are active, but have differing kinetic constants [, ]. ACE is well-known as a key part of the renin-angiotensin system that regulates blood pressure and ACE inhibitors are important for the treatment of hypertension [, ].An ACE homologue, ACE2 (MEROPS identifier M02.006), has been identified in humans that differs from ACE; it preferentially removes carboxy-terminal hydrophobic or basic amino acids and appears to be important in cardiac function [, ]. ACE3 is a non-peptidase homologue included in this entry which lacks Glu378 in the HEXXH motif.A number of insect enzymes have been shown to be similar to peptidyl-dipeptidase A, these containing a single catalytic domain [, ].
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Publication
7674922 | -
 
First Author: Rawlings ND
Year: 1995
Journal: Methods Enzymol
Title: Evolutionary families of metallopeptidases.
Volume: 248
Pages: 183-228
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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