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Search results 1 to 68 out of 68 for Acmsd

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Hits by Strain

Hits by Category

Type Details Score
Gene
130013 | ACMSD
Type: gene
Organism: human
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Gene
515030 | ACMSD
Type: gene
Organism: cattle
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Gene
424288 | ACMSD
Type: gene
Organism: chicken
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Gene
557166 | acmsd
Type: gene
Organism: zebrafish
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Gene
708917 | ACMSD
Type: gene
Organism: macaque, rhesus
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Gene
100488272 | acmsd
Type: gene
Organism: frog, western clawed
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Gene
171385 | Acmsd
Type: gene
Organism: rat
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Gene
476125 | ACMSD
Type: gene
Organism: dog, domestic
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Gene
459627 | ACMSD
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2386323 | Acmsd
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR032465 | ACMSD
Type: Family
Description: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, also known as picolinate carboxylase or ACMSD, is a member of the amidohydrolase superfamily involved in tryptophan metabolism [, ]. It converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMSD has medical importance as its substrate ACMS is unstable and dehydrates to quinolinic acid (QUIN, QA), not only a key precursor of NAD, but also a potent neurotoxin []. Elevated levels of QUIN have been observed in several neuropsychiatric and neurodegenerative conditions [, , ].The entry also includes decarboxylases OrsB, MacB and YanB, and salicylate decarboxylase.YanB is a decarboxylase and part of the gene cluster that mediates the biosynthesis of yanuthone D, a fungal isoprenoid epoxycyclohexenone that acts as an antibiotic against fungi and bacteria []. Salicylate decarboxylase has been shown to catalyse both the decarboxylation of salicylic acid to produce phenol, and the carboxylation of phenol to form salicylic acid [].
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Publication
- | J:78814
   
First Author: Fukuoka SI
Year: 2002
Journal: GenBank Submission
Title: Mus musculus ACMSD mRNA for 2-amino-3-carboxylmuconate-6-semialdehy de decarboxylase, partial cds
Pages: AB071419
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Publication
12940508 | -
First Author: Stone TW
Year: 2003
Journal: Clin Chem Lab Med
Title: Tryptophan metabolites and brain disorders.
Volume: 41
Issue: 7
Pages: 852-9
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Publication
15206729 | -
 
First Author: Guillemin GJ
Year: 2003
Journal: Adv Exp Med Biol
Title: Quinolinic acid in the pathogenesis of Alzheimer's disease.
Volume: 527
Pages: 167-76
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Publication
15206726 | -
 
First Author: Guidetti P
Year: 2003
Journal: Adv Exp Med Biol
Title: 3-Hydroxykynurenine and quinolinate: pathogenic synergism in early grade Huntington's disease?
Volume: 527
Pages: 137-45
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Publication
16716073 | -
First Author: Li T
Year: 2006
Journal: Biochemistry
Title: Alpha-amino-beta-carboxymuconic-epsilon-semialdehyde decarboxylase (ACMSD) is a new member of the amidohydrolase superfamily.
Volume: 45
Issue: 21
Pages: 6628-34
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Publication
19843166 | -
First Author: Garavaglia S
Year: 2009
Journal: FEBS J
Title: The crystal structure of human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis.
Volume: 276
Issue: 22
Pages: 6615-23
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Publication
17288562 | -
First Author: Pucci L
Year: 2007
Journal: FEBS J
Title: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism.
Volume: 274
Issue: 3
Pages: 827-40
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Publication
24684908 | -
First Author: Holm DK
Year: 2014
Journal: Chem Biol
Title: Molecular and chemical characterization of the biosynthesis of the 6-MSA-derived meroterpenoid yanuthone D in Aspergillus niger.
Volume: 21
Issue: 4
Pages: 519-529
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Publication
20188702 | -
First Author: Kirimura K
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Enzymatic Kolbe-Schmitt reaction to form salicylic acid from phenol: enzymatic characterization and gene identification of a novel enzyme, Trichosporon moniliiforme salicylic acid decarboxylase.
Volume: 394
Issue: 2
Pages: 279-84
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Protein
Q8R519
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: false
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Protein
Q3TNK0
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: false
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Publication
12140278 | J:79121
First Author: Fukuoka S
Year: 2002
Journal: J Biol Chem
Title: Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis".
Volume: 277
Issue: 38
Pages: 35162-7
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Publication
30356218 | J:267688
First Author: Katsyuba E
Year: 2018
Journal: Nature
Title: De novo NAD+ synthesis enhances mitochondrial function and improves health.
Volume: 563
Issue: 7731
Pages: 354-359
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Protein Coding Gene
MGP_CAROLIEiJ_G0014538 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016421 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016404 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2386323 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016825 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015771 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016163 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016269 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016340 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016293 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016861 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015557 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027774 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015345 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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GO Term
GO:0001760 | aminocarboxymuconate-semialdehyde decarboxylase activity
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Publication
30380424 | J:271258
First Author: Palzer L
Year: 2018
Journal: Cell Rep
Title: Alpha-Amino-Beta-Carboxy-Muconate-Semialdehyde Decarboxylase Controls Dietary Niacin Requirements for NAD+ Synthesis.
Volume: 25
Issue: 5
Pages: 1359-1370.e4
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