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Search results 1 to 100 out of 143 for Acod1

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Hits by Category

Hits by Strain

Type Details Score
Gene
730249 | ACOD1
Type: gene
Organism: human
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Gene
100490699 | acod1
Type: gene
Organism: frog, western clawed
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Gene
107131195 | ACOD1
Type: gene
Organism: cattle
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Gene
306127 | Acod1
Type: gene
Organism: rat
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Gene
485496 | ACOD1
Type: gene
Organism: dog, domestic
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Gene
452753 | ACOD1
Type: gene
Organism: chimpanzee
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Gene
418812 | ACOD1
Type: gene
Organism: chicken
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Gene
795305 | acod1
Type: gene
Organism: zebrafish
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Gene
695991 | ACOD1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:103206 | Acod1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
35838338 | J:333766
First Author: Pires-Afonso Y
Year: 2022
Journal: Mol Oncol
Title: Elucidating tumour-associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency.
Volume: 16
Issue: 17
Pages: 3167-3191
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Publication
38302438 | J:346669
First Author: Eberhart T
Year: 2024
Journal: Cell Death Dis
Title: ACOD1 deficiency offers protection in a mouse model of diet-induced obesity by maintaining a healthy gut microbiota.
Volume: 15
Issue: 2
Pages: 105
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Publication
38324982 | J:360351
 
First Author: Luo Z
Year: 2024
Journal: EBioMedicine
Title: Targeted macrophage phagocytosis by Irg1/itaconate axis improves the prognosis of intracerebral hemorrhagic stroke and peritonitis.
Volume: 101
Pages: 104993
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Publication
37737207 | J:341054
First Author: Zhang L
Year: 2023
Journal: Cell Death Dis
Title: Mitochondrial IRG1 traps MCL-1 to induce hepatocyte apoptosis and promote carcinogenesis.
Volume: 14
Issue: 9
Pages: 625
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Publication
31548418 | J:325954
First Author: Chen F
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Crystal structure of cis-aconitate decarboxylase reveals the impact of naturally occurring human mutations on itaconate synthesis.
Volume: 116
Issue: 41
Pages: 20644-20654
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Publication
38964754 | J:355013
     
First Author: Kachler K
Year: 2024
Journal: Ann Rheum Dis
Title: Acod1-mediated inhibition of aerobic glycolysis suppresses osteoclast differentiation and attenuates bone erosion in arthritis.
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Publication
38305778 | J:357731
   
First Author: Mainali R
Year: 2024
Journal: Elife
Title: Itaconate stabilizes CPT1a to enhance lipid utilization during inflammation.
Volume: 12
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Publication
38713770 | J:354441
First Author: Ji J
Year: 2024
Journal: J Leukoc Biol
Title: IRG1/ACOD1 promotes neutrophil reverse migration and alleviates local inflammation.
Volume: 116
Issue: 4
Pages: 854-863
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Publication
35025971 | J:322524
First Author: Sohail A
Year: 2022
Journal: PLoS Pathog
Title: Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection.
Volume: 18
Issue: 1
Pages: e1010219
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Publication
35457208 | J:324303
 
First Author: Kim HW
Year: 2022
Journal: Int J Mol Sci
Title: Aconitate Decarboxylase 1 Deficiency Exacerbates Mouse Colitis Induced by Dextran Sodium Sulfate.
Volume: 23
Issue: 8
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Publication
39351225 | J:355004
 
First Author: Schwab AD
Year: 2024
Journal: Front Immunol
Title: Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.
Volume: 15
Pages: 1432334
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Publication
39515327 | J:359310
First Author: Lin H
Year: 2024
Journal: Cancer Cell
Title: Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance.
Volume: 42
Issue: 12
Pages: 2032-2044.e6
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Publication
32255424 | J:291697
   
First Author: Sun KA
Year: 2020
Journal: Elife
Title: Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response.
Volume: 9
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Publication
38325373 | J:346161
First Author: Ramalho T
Year: 2024
Journal: Cell Metab
Title: Itaconate impairs immune control of Plasmodium by enhancing mtDNA-mediated PD-L1 expression in monocyte-derived dendritic cells.
Volume: 36
Issue: 3
Pages: 484-497.e6
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Publication
37793345 | J:341512
First Author: Zhao Y
Year: 2023
Journal: Cell Metab
Title: Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1.
Volume: 35
Issue: 10
Pages: 1688-1703.e10
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Publication
35927796 | J:333764
First Author: Frieler RA
Year: 2022
Journal: Obesity (Silver Spring)
Title: Aconitate decarboxylase 1 regulates glucose homeostasis and obesity in mice.
Volume: 30
Issue: 9
Pages: 1818-1830
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Publication
34699789 | J:321408
 
First Author: Vigil TM
Year: 2022
Journal: Exp Neurol
Title: Aconitate decarboxylase 1 suppresses cerebral ischemia-reperfusion injury in mice.
Volume: 347
Pages: 113902
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Publication
38085578 | J:353421
 
First Author: Song J
Year: 2023
Journal: J Clin Invest
Title: Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice.
Volume: 134
Issue: 3
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Publication
36001682 | J:330058
First Author: Wu R
Year: 2022
Journal: Sci Transl Med
Title: Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis.
Volume: 14
Issue: 659
Pages: eabo2028
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Protein Coding Gene
MGP_CAROLIEiJ_G0019571 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021627 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021585 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021561 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_103206 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020886 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021337 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021529 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021465 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020629 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030588 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020467 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
14500577 | J:196639
First Author: Cheon YP
Year: 2003
Journal: Endocrinology
Title: Immune-responsive gene 1 is a novel target of progesterone receptor and plays a critical role during implantation in the mouse.
Volume: 144
Issue: 12
Pages: 5623-30
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Publication
19014335 | J:196718
First Author: Degrandi D
Year: 2009
Journal: J Interferon Cytokine Res
Title: The proinflammatory cytokine-induced IRG1 protein associates with mitochondria.
Volume: 29
Issue: 1
Pages: 55-67
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Publication
23610393 | J:196954
First Author: Michelucci A
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
Volume: 110
Issue: 19
Pages: 7820-5
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Publication
38986577 | J:355012
First Author: Kieler M
Year: 2024
Journal: Ann Rheum Dis
Title: Itaconate is a metabolic regulator of bone formation in homeostasis and arthritis.
Volume: 83
Issue: 11
Pages: 1465-1479
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Publication
27189937 | J:235002
First Author: Cordes T
Year: 2016
Journal: J Biol Chem
Title: Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels.
Volume: 291
Issue: 27
Pages: 14274-84
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Publication
27374498 | J:240363
First Author: Lampropoulou V
Year: 2016
Journal: Cell Metab
Title: Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Volume: 24
Issue: 1
Pages: 158-66
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Publication
36753565 | J:355007
First Author: Lei I
Year: 2023
Journal: Sci Transl Med
Title: Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function.
Volume: 15
Issue: 682
Pages: eade3782
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Publication
38157387 | J:355009
First Author: Petnicki-Ocwieja T
Year: 2023
Journal: PLoS Pathog
Title: Borrelia burgdorferi initiates early transcriptional re-programming in macrophages that supports long-term suppression of inflammation.
Volume: 19
Issue: 12
Pages: e1011886
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Publication
39156902 | J:358529
 
First Author: Siddique MNAA
Year: 2024
Journal: Front Immunol
Title: Divergent effects of itaconate isomers on Coxiella burnetii growth in macrophages and in axenic culture.
Volume: 15
Pages: 1427457
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Publication
32428444 | J:296546
First Author: Riquelme SA
Year: 2020
Journal: Cell Metab
Title: Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation.
Volume: 31
Issue: 6
Pages: 1091-1106.e6
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Publication
31704924 | J:281743
First Author: Liao ST
Year: 2019
Journal: Nat Commun
Title: 4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects.
Volume: 10
Issue: 1
Pages: 5091
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Publication
33097591 | J:355208
 
First Author: Ogger PP
Year: 2020
Journal: Sci Immunol
Title: Itaconate controls the severity of pulmonary fibrosis.
Volume: 5
Issue: 52
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Publication
36376563 | J:339480
First Author: Zhao H
Year: 2022
Journal: Nat Metab
Title: Myeloid-derived itaconate suppresses cytotoxic CD8(+) T cells and promotes tumour growth.
Volume: 4
Issue: 12
Pages: 1660-1673
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Publication
38763433 | J:351323
 
First Author: Tada M
Year: 2024
Journal: Clin Immunol
Title: Itaconate reduces proliferation and migration of fibroblast-like synoviocytes and ameliorates arthritis models.
Volume: 264
Pages: 110255
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Publication
35149415 | J:323324
 
First Author: Roberts LM
Year: 2022
Journal: Cell Immunol
Title: Itaconate indirectly influences expansion of effector T cells following vaccination with Francisella tularensis live vaccine strain.
Volume: 373
Pages: 104485
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Publication
37449973 | J:349173
   
First Author: Mateska I
Year: 2023
Journal: Elife
Title: Succinate mediates inflammation-induced adrenocortical dysfunction.
Volume: 12
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Publication
12893884 | J:86286
First Author: Chen B
Year: 2003
Journal: Mol Endocrinol
Title: Progesterone regulation of the mammalian ortholog of methylcitrate dehydratase (immune response gene 1) in the uterine epithelium during implantation through the protein kinase C pathway.
Volume: 17
Issue: 11
Pages: 2340-54
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Publication
23609450 | J:196955
First Author: Li Y
Year: 2013
Journal: J Biol Chem
Title: Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species.
Volume: 288
Issue: 23
Pages: 16225-34
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Publication
8207206 | J:18633
First Author: Lee CG
Year: 1994
Journal: J Immunol
Title: Molecular cloning and characterization of a murine LPS-inducible cDNA.
Volume: 152
Issue: 12
Pages: 5758-67
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Publication
38564634 | J:355010
First Author: Cyr Y
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: The IRG1-itaconate axis protects from cholesterol-induced inflammation and atherosclerosis.
Volume: 121
Issue: 15
Pages: e2400675121
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Publication
36735777 | J:355413
First Author: Reynolds MB
Year: 2023
Journal: Sci Adv
Title: Cardiolipin coordinates inflammatory metabolic reprogramming through regulation of Complex II disassembly and degradation.
Volume: 9
Issue: 5
Pages: eade8701
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Publication
37793346 | J:355008
First Author: Tomlinson KL
Year: 2023
Journal: Cell Metab
Title: Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection.
Volume: 35
Issue: 10
Pages: 1767-1781.e6
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Publication
29511063 | J:261599
First Author: Nair S
Year: 2018
Journal: J Exp Med
Title: Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection.
Volume: 215
Issue: 4
Pages: 1035-1045
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Publication
37707952 | J:342270
 
First Author: Crossley JL
Year: 2023
Journal: JCI Insight
Title: Itaconate-producing neutrophils regulate local and systemic inflammation following trauma.
Volume: 8
Issue: 20
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Publication
38329873 | J:351968
First Author: Shi W
Year: 2024
Journal: Cell Rep
Title: Lactic acid induces transcriptional repression of macrophage inflammatory response via histone acetylation.
Volume: 43
Issue: 2
Pages: 113746
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Publication
31997373 | J:355135
First Author: Yi Z
Year: 2020
Journal: Hepatology
Title: Immune-Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2-Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia-Reperfusion Injury.
Volume: 72
Issue: 4
Pages: 1394-1411
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Publication
38600378 | J:355011
First Author: Auger JP
Year: 2024
Journal: Nature
Title: Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.
Volume: 629
Issue: 8010
Pages: 184-192
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Publication
34095879 | J:308353
First Author: Singh S
Year: 2021
Journal: Cell Rep Med
Title: Integrative metabolomics and transcriptomics identifies itaconate as an adjunct therapy to treat ocular bacterial infection.
Volume: 2
Issue: 5
Pages: 100277
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Publication
39406969 | J:357725
     
First Author: O'Carroll SM
Year: 2024
Journal: Nat Metab
Title: Itaconate drives mtRNA-mediated type I interferon production through inhibition of succinate dehydrogenase.
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Publication
38071226 | J:350372
First Author: Gu X
Year: 2023
Journal: Nat Commun
Title: Itaconate promotes hepatocellular carcinoma progression by epigenetic induction of CD8(+) T-cell exhaustion.
Volume: 14
Issue: 1
Pages: 8154
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Publication
36919698 | J:355006
 
First Author: Zeng YR
Year: 2023
Journal: J Clin Invest
Title: The immunometabolite itaconate stimulates OXGR1 to promote mucociliary clearance during the pulmonary innate immune response.
Volume: 133
Issue: 6
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Publication
38555305 | J:350000
First Author: Daneshmandi S
Year: 2024
Journal: Nat Commun
Title: Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies.
Volume: 15
Issue: 1
Pages: 2803
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Publication
37640963 | J:339869
     
First Author: Lian H
Year: 2023
Journal: Nat Microbiol
Title: Parkinson's disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella.
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Publication
7721348 | J:25077
First Author: Lee CG
Year: 1995
Journal: Immunogenetics
Title: Cloning and analysis of gene regulation of a novel LPS-inducible cDNA.
Volume: 41
Issue: 5
Pages: 263-70
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Publication
32703879 | J:297588
First Author: Chen M
Year: 2020
Journal: Science
Title: Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against Salmonella.
Volume: 369
Issue: 6502
Pages: 450-455
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Publication
34686860 | J:320341
First Author: Fujiwara H
Year: 2021
Journal: Nat Immunol
Title: Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
Volume: 22
Issue: 11
Pages: 1440-1451
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Publication
39351765 | J:358081
     
First Author: McBride MA
Year: 2024
Journal: J Leukoc Biol
Title: Immunoresponsive Gene 1 Facilitates TLR4-agonist-Induced Augmentation of Innate Antimicrobial Immunity.
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Publication
37257722 | J:341028
 
First Author: Huang J
Year: 2023
Journal: Biochem Pharmacol
Title: Macrophage scavenger receptor A1 antagonizes abdominal aortic aneurysm via upregulating IRG1.
Volume: 213
Pages: 115631
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Publication
21731484 | J:182190
First Author: Coers J
Year: 2011
Journal: PLoS Pathog
Title: Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections.
Volume: 7
Issue: 6
Pages: e1001346
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Publication
35655024 | J:334086
First Author: He W
Year: 2022
Journal: Nat Metab
Title: Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
Volume: 4
Issue: 5
Pages: 524-533
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Publication
32791101 | J:295186
First Author: Hooftman A
Year: 2020
Journal: Cell Metab
Title: The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.
Volume: 32
Issue: 3
Pages: 468-478.e7
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Publication
36724077 | J:355005
First Author: Tomlinson KL
Year: 2023
Journal: Cell Rep
Title: Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst.
Volume: 42
Issue: 2
Pages: 112064
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Publication
12160731 | J:78120
First Author: Peterson KA
Year: 2002
Journal: Genomics
Title: Functional and comparative genomic analysis of the piebald deletion region of mouse chromosome 14.
Volume: 80
Issue: 2
Pages: 172-84
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Publication
35864246 | J:339479
First Author: Schuster EM
Year: 2022
Journal: Nat Metab
Title: TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages.
Volume: 4
Issue: 7
Pages: 856-866
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Publication
37566679 | J:339864
First Author: Forde AJ
Year: 2023
Journal: Sci Immunol
Title: Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection.
Volume: 8
Issue: 86
Pages: eadg3517
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Publication
33691097 | J:334258
First Author: Bambouskova M
Year: 2021
Journal: Cell Rep
Title: Itaconate confers tolerance to late NLRP3 inflammasome activation.
Volume: 34
Issue: 10
Pages: 108756
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Publication
37865673 | J:342082
First Author: Harvest CK
Year: 2023
Journal: Nat Commun
Title: An innate granuloma eradicates an environmental pathogen using Gsdmd and Nos2.
Volume: 14
Issue: 1
Pages: 6686
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Publication
29670287 | J:261637
First Author: Bambouskova M
Year: 2018
Journal: Nature
Title: Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis.
Volume: 556
Issue: 7702
Pages: 501-504
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Publication
34644537 | J:319416
First Author: Faas M
Year: 2021
Journal: Immunity
Title: IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation.
Volume: 54
Issue: 11
Pages: 2531-2546.e5
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Publication
32516576 | J:296582
First Author: Hsieh WY
Year: 2020
Journal: Cell Metab
Title: Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome.
Volume: 32
Issue: 1
Pages: 128-143.e5
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Publication
14566968 | J:86296
First Author: McCusker RH
Year: 2003
Journal: J Cell Physiol
Title: Zinc partitions insulin-like growth factors (IGFs) from soluble IGF binding protein (IGFBP)-5 to the cell surface receptors of BC3H-1 muscle cells.
Volume: 197
Issue: 3
Pages: 388-99
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Publication
8790420 | J:41070
First Author: Smallwood PM
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development.
Volume: 93
Issue: 18
Pages: 9850-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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