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Search results 1 to 100 out of 141 for Actn4

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Type Details Score
Gene
81 | ACTN4
Type: gene
Organism: human
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Gene
456010 | ACTN4
Type: gene
Organism: chimpanzee
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Gene
484526 | ACTN4
Type: gene
Organism: dog, domestic
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Gene
522269 | ACTN4
Type: gene
Organism: cattle
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Gene
396024 | ACTN4
Type: gene
Organism: chicken
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Gene
322221 | actn4
Type: gene
Organism: zebrafish
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Gene
693666 | ACTN4
Type: gene
Organism: macaque, rhesus
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Gene
448522 | actn4
Type: gene
Organism: frog, western clawed
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Gene
63836 | Actn4
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1890773 | Actn4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33228246 | J:306605
 
First Author: Lin YH
Year: 2020
Journal: Biomedicines
Title: ACTN4 Mediates SEPT14 Mutation-Induced Sperm Head Defects.
Volume: 8
Issue: 11
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Publication
30776251 | J:292064
First Author: Peng W
Year: 2019
Journal: FASEB J
Title: Trophoblastic proliferation and invasion regulated by ACTN4 is impaired in early onset preeclampsia.
Volume: 33
Issue: 5
Pages: 6327-6338
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Publication
12707390 | J:132794
First Author: Michaud JL
Year: 2003
Journal: J Am Soc Nephrol
Title: Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4.
Volume: 14
Issue: 5
Pages: 1200-11
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Publication
29873512 | J:280760
First Author: Yee A
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Proteostasis as a therapeutic target in glomerular injury associated with mutant α-actinin-4.
Volume: 315
Issue: 4
Pages: F954-F966
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Publication
19640905 | J:152805
First Author: Cybulsky AV
Year: 2009
Journal: Am J Physiol Renal Physiol
Title: Glomerular epithelial cell injury associated with mutant alpha-actinin-4.
Volume: 297
Issue: 4
Pages: F987-95
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Publication
24662305 | J:212476
First Author: Read NC
Year: 2014
Journal: Biochim Biophys Acta
Title: Ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis.
Volume: 1842
Issue: 7
Pages: 1028-40
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Publication
22673512 | J:185498
First Author: Yu H
Year: 2012
Journal: FEBS Lett
Title: α-Actinin4 nuclear translocation mediates gonadotropin-releasing hormone stimulation of follicle-stimulating hormone β-subunit gene transcription in LβT2 cells.
Volume: 586
Issue: 10
Pages: 1466-71
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Publication
29378953 | J:259833
First Author: Feng D
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch.
Volume: 115
Issue: 7
Pages: 1517-1522
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Publication
15208719 | J:90755
First Author: Yao J
Year: 2004
Journal: PLoS Biol
Title: Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein.
Volume: 2
Issue: 6
Pages: e167
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Publication
18185509 | J:152879
First Author: Henderson JM
Year: 2008
Journal: Kidney Int
Title: Mice with altered alpha-actinin-4 expression have distinct morphologic patterns of glomerular disease.
Volume: 73
Issue: 6
Pages: 741-50
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Publication
17082197 | J:118122
First Author: Dandapani SV
Year: 2007
Journal: J Biol Chem
Title: Alpha-actinin-4 is required for normal podocyte adhesion.
Volume: 282
Issue: 1
Pages: 467-77
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Publication
16837921 | J:115805
First Author: Michaud JL
Year: 2006
Journal: Kidney Int
Title: FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes.
Volume: 70
Issue: 6
Pages: 1054-61
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Publication
15633123 | J:114115
First Author: Honda K
Year: 2005
Journal: Gastroenterology
Title: Actinin-4 increases cell motility and promotes lymph node metastasis of colorectal cancer.
Volume: 128
Issue: 1
Pages: 51-62
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Publication
21085685 | J:166814
First Author: Shao H
Year: 2010
Journal: PLoS One
Title: α-actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts.
Volume: 5
Issue: 11
Pages: e13921
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Publication
35101665 | J:322641
 
First Author: Li Y
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Angiopoietin-like protein 4 promotes hyperlipidemia-induced renal injury by down-regulating the expression of ACTN4.
Volume: 595
Pages: 69-75
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Publication
10964513 | J:64480
First Author: Dear TN
Year: 2000
Journal: Genomics
Title: Gene structure, chromosomal localization, and expression pattern of Capn12, a new member of the calpain large subunit gene family.
Volume: 68
Issue: 2
Pages: 152-60
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Publication
25411248 | J:221512
First Author: Zhao X
Year: 2015
Journal: J Biol Chem
Title: α-Actinin 4 potentiates nuclear factor κ-light-chain-enhancer of activated B-cell (NF-κB) activity in podocytes independent of its cytoplasmic actin binding function.
Volume: 290
Issue: 1
Pages: 338-49
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Protein Coding Gene
MGP_CAROLIEiJ_G0029468 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031945 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031877 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031952 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031671 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1890773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032416 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031006 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0031637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031746 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031869 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031782 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032446 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030731 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0031115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0012702 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0030564 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
24940801 | J:226883
First Author: Grgic I
Year: 2014
Journal: Kidney Int
Title: Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo.
Volume: 86
Issue: 6
Pages: 1116-29
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Publication
10954430 | J:113905
 
First Author: Araki N
Year: 2000
Journal: J Cell Sci
Title: Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages: analysis by fluorescence ratio imaging.
Volume: 113 ( Pt 18)
Pages: 3329-40
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Publication
17901210 | J:125758
First Author: Weins A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity.
Volume: 104
Issue: 41
Pages: 16080-5
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Publication
20197409 | J:158735
First Author: Kumeta M
Year: 2010
Journal: J Cell Sci
Title: Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4.
Volume: 123
Issue: Pt 7
Pages: 1020-30
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GXD Expression
GXD Expression
   
Probe: MGI:3710842
Assay Type: RT-PCR
Annotation Date: 2007-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3710874
Age: embryonic day 2.0
Image: 2
Specimen Label: 4C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3710842
Assay Type: RT-PCR
Annotation Date: 2007-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3710874
Age: embryonic day 3.0
Image: 2
Specimen Label: MO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3710842
Assay Type: RT-PCR
Annotation Date: 2007-06-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3710874
Age: embryonic day 3.5
Image: 2
Specimen Label: BL
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3832236
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:3832237
Age: embryonic day 14.0
Image: S7
Specimen Label: E14 wt h
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3832236
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:3832237
Age: embryonic day 14.0
Image: S7
Specimen Label: E14 wt i
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3832236
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832237
Age: postnatal adult
Image: S7
Specimen Label: Adult +/+ j
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:3832236
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832237
Age: postnatal adult
Image: S7
Specimen Label: Adult +/+ k
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
   
Probe: MGI:3832236
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832237
Age: postnatal
Image: S7
Specimen Label: MBNL1 +/- l
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
   
Probe: MGI:3832236
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832237
Age: postnatal
Image: S7
Specimen Label: MBNL1 +/- m
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Probe: MGI:3832236
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832237
Age: postnatal
Image: S7
Specimen Label: delta3/delta3 n
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
   
Probe: MGI:3832236
Assay Type: RT-PCR
Annotation Date: 2009-02-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3832237
Age: postnatal
Image: S7
Specimen Label: delta3/delta3 o
Detected: true
Specimen Num: 15
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Publication
18332111 | J:136002
First Author: Nakatsuji H
Year: 2008
Journal: Mol Cell Biol
Title: Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions.
Volume: 28
Issue: 10
Pages: 3324-35
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Publication
23557398 | J:198978
First Author: Foley KS
Year: 2013
Journal: Biochem J
Title: An analysis of splicing, actin-binding properties, heterodimerization and molecular interactions of the non-muscle α-actinins.
Volume: 452
Issue: 3
Pages: 477-88
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Publication
23890175 | J:201396
First Author: Sakane A
Year: 2013
Journal: Genes Cells
Title: Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.
Volume: 18
Issue: 9
Pages: 810-22
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Publication
21784188 | J:176471
First Author: Yang N
Year: 2011
Journal: Bone
Title: α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse.
Volume: 49
Issue: 4
Pages: 790-8
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Publication
37730132 | J:344074
First Author: Hsu MF
Year: 2024
Journal: Biochim Biophys Acta Mol Cell Res
Title: Protein tyrosine phosphatase 1B is a regulator of alpha-actinin4 in the glomerular podocyte.
Volume: 1871
Issue: 1
Pages: 119590
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Publication
12960352 | J:85387
First Author: Daniliuc S
Year: 2003
Journal: J Immunol
Title: Hypoxia inactivates inducible nitric oxide synthase in mouse macrophages by disrupting its interaction with alpha-actinin 4.
Volume: 171
Issue: 6
Pages: 3225-32
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Publication
16944923 | J:117470
First Author: Chen VC
Year: 2006
Journal: J Proteome Res
Title: Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins.
Volume: 5
Issue: 9
Pages: 2123-34
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Publication
16751418 | J:132348
First Author: Zhao Z
Year: 2006
Journal: J Immunol
Title: Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin.
Volume: 176
Issue: 12
Pages: 7704-14
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Publication
21940706 | J:198548
First Author: Sánchez-Ponce D
Year: 2012
Journal: Cereb Cortex
Title: Colocalization of α-actinin and synaptopodin in the pyramidal cell axon initial segment.
Volume: 22
Issue: 7
Pages: 1648-61
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Publication
11724819 | J:148606
First Author: Hüttelmaier S
Year: 2001
Journal: J Cell Biol
Title: Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.
Volume: 155
Issue: 5
Pages: 775-86
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Publication
15841212 | J:98090
First Author: Asanuma K
Year: 2005
Journal: J Clin Invest
Title: Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner.
Volume: 115
Issue: 5
Pages: 1188-98
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Publication
22693585 | J:187422
First Author: Collin GB
Year: 2012
Journal: PLoS One
Title: The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway.
Volume: 7
Issue: 5
Pages: e37925
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Publication
16501493 | J:136508
First Author: Fan Q
Year: 2006
Journal: Kidney Int
Title: The relationship among nephrin, podocin, CD2AP, and alpha-actinin might not be a true 'interaction' in podocyte.
Volume: 69
Issue: 7
Pages: 1207-15
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Publication
20215401 | J:158675
First Author: Beqqali A
Year: 2010
Journal: J Cell Sci
Title: CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.
Volume: 123
Issue: Pt 7
Pages: 1141-50
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Publication
23515331 | J:195528
First Author: Roca-Cusachs P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation.
Volume: 110
Issue: 15
Pages: E1361-70
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Publication
25962121 | J:228459
First Author: Schiffer M
Year: 2015
Journal: Nat Med
Title: Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.
Volume: 21
Issue: 6
Pages: 601-9
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Publication
20368620 | J:158797
First Author: Gokhin DS
Year: 2010
Journal: J Cell Biol
Title: Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.
Volume: 189
Issue: 1
Pages: 95-109
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Publication
12782671 | J:83911
First Author: Kos CH
Year: 2003
Journal: J Clin Invest
Title: Mice deficient in alpha-actinin-4 have severe glomerular disease.
Volume: 111
Issue: 11
Pages: 1683-90
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Publication
35602553 | J:325068
 
First Author: Rudolf MA
Year: 2022
Journal: Front Cell Neurosci
Title: Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear.
Volume: 16
Pages: 859882
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Publication
18425115 | J:145664
First Author: Nygren JM
Year: 2008
Journal: Nat Cell Biol
Title: Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.
Volume: 10
Issue: 5
Pages: 584-92
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Publication
12217315 | J:78764
First Author: Sadl V
Year: 2002
Journal: Dev Biol
Title: The mouse Kreisler (Krml1/MafB) segmentation gene is required for differentiation of glomerular visceral epithelial cells.
Volume: 249
Issue: 1
Pages: 16-29
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Publication
15465019 | J:93130
First Author: Keicher C
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Phosphorylation of mouse LASP-1 on threonine 156 by cAMP- and cGMP-dependent protein kinase.
Volume: 324
Issue: 1
Pages: 308-16
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Publication
29114040 | J:293086
First Author: Guo B
Year: 2018
Journal: J Am Soc Nephrol
Title: Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.
Volume: 29
Issue: 2
Pages: 416-422
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Publication
11440986 | J:70373
First Author: Mills M
Year: 2001
Journal: Hum Mol Genet
Title: Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.
Volume: 10
Issue: 13
Pages: 1335-46
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Publication
36706168 | J:333147
First Author: Wu T
Year: 2023
Journal: PLoS Genet
Title: Filamin C is Essential for mammalian myocardial integrity.
Volume: 19
Issue: 1
Pages: e1010630
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Publication
16998848 | J:119954
First Author: Cui XS
Year: 2007
Journal: Mol Reprod Dev
Title: Transcription profile in mouse four-cell, morula, and blastocyst: Genes implicated in compaction and blastocoel formation.
Volume: 74
Issue: 2
Pages: 133-43
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Publication
36899856 | J:334092
 
First Author: Broadway-Stringer S
Year: 2023
Journal: Cells
Title: Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2.
Volume: 12
Issue: 5
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Publication
31062503 | J:288722
First Author: Nilsson D
Year: 2019
Journal: Physiol Rep
Title: Foxc2 is essential for podocyte function.
Volume: 7
Issue: 9
Pages: e14083
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Publication
16319116 | J:104891
First Author: Osafune K
Year: 2006
Journal: Development
Title: Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.
Volume: 133
Issue: 1
Pages: 151-61
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Publication
19075228 | J:142671
First Author: Kalsotra A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart.
Volume: 105
Issue: 51
Pages: 20333-8
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Publication
23055941 | J:193640
First Author: Lo JC
Year: 2012
Journal: PLoS Genet
Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
Volume: 8
Issue: 10
Pages: e1002969
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Publication
29539633 | J:261316
First Author: Perez-Garcia V
Year: 2018
Journal: Nature
Title: Placentation defects are highly prevalent in embryonic lethal mouse mutants.
Volume: 555
Issue: 7697
Pages: 463-468
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Publication
- | J:239583
     
First Author: Mouse Genome Informatics and the Consortium: Deciphering the Mechanisms of Developmental Disorders (DMDD)
Year: 2017
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Deciphering the Mechanisms of Developmental Disorders (DMDD)
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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