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Search results 1 to 100 out of 764 for Acvr1

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Type Details Score
Gene
90 | ACVR1
Type: gene
Organism: human
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Gene
470565 | ACVR1
Type: gene
Organism: chimpanzee
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Gene
478757 | ACVR1
Type: gene
Organism: dog, domestic
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Gene
338068 | ACVR1
Type: gene
Organism: cattle
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Gene
697935 | ACVR1
Type: gene
Organism: macaque, rhesus
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Gene
550111 | acvr1
Type: gene
Organism: frog, western clawed
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Gene
79558 | Acvr1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:87911 | Acvr1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: There is weak staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Acvr1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: There is moderate staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Acvr1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: There is weak staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Acvr1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: There is moderate staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Acvr1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Acvr1 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Acvr1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Acvr1 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: There is moderate staining in the mantle zone of the VMH and ARH nuclei and weak staining in the anterior ID. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH nucleus, the AVH and posterior ID.
Specimen Label: Acvr1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: There is moderate staining in the mantle zone of the VMH and ARH nuclei. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH nucleus, the AVH and anterior and posterior IDs.
Specimen Label: Acvr1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: There is moderate staining in the mantle zone of the ARH nucleus and weak in the VMH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH and DMH nuclei, the AVH, the DAH and the PH.
Specimen Label: Acvr1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450846
Age: embryonic day 11.5
Image: Acvr1 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Label: Acvr1 - E11.5
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: There is moderate staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones and the TT.
Specimen Label: Acvr1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: There is moderate staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones and the TT.
Specimen Label: Acvr1 - E14.5
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: There is moderate staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones.
Specimen Label: Acvr1 - E16.5
Detected: true
Specimen Num: 4
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•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450846
Age: embryonic day 11.5
Image: Acvr1 - E11.5
Note: Staining is moderate in the VZ of the VMH nucleus, premam zone & ARH nucleus. Staining is either absent or ubiquitous in the VZ of dorsal thalamus, prethalamus, dorsal & ventral POAs, PVH nucleus, AVH, anterior & posterior IDs, mam & supramam zones & TT.
Specimen Label: Acvr1 - E11.5
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Acvr1 - E12.5
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Label: Acvr1 - E14.5
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Acvr1 - E16.5
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450846
Age: embryonic day 11.5
Image: Acvr1 - E11.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Label: Acvr1 - E11.5
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Acvr1 - E12.5
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Acvr1 - E14.5
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Acvr1 - E16.5
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Acvr1 - E12.5
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Acvr1 - E14.5
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
Specimen Label: Acvr1 - E16.5
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Acvr1 - E12.5
Specimen Num: 2
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•
GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: There is strong staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences.
Specimen Label: Acvr1 - E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450846
Age: embryonic day 11.5
Image: Acvr1 - E11.5
Note: There is weak staining in the MZ of anterior ID. Staining is either absent or ubiquitous in the MZ of the dorsal thalamus, prethalamus, dorsal & ventral POAs, the PVH, VMH & ARH nuclei, the AVH, posterior ID, the premam, mam & supramam zones & the TT.
Specimen Label: Acvr1 - E11.5
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450846
Age: embryonic day 12.5
Image: Acvr1 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Label: Acvr1 - E12.5
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450846
Age: embryonic day 14.5
Image: Acvr1 - E14.5
Note: There is strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Specimen Label: Acvr1 - E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: There is strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Specimen Label: Acvr1 - E16.5
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Acvr1 - E16.5
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Acvr1 - E16.5
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442686
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450846
Age: embryonic day 16.5
Image: Acvr1 - E16.5
Note: There is strong staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences.
Specimen Label: Acvr1 - E16.5
Detected: true
Specimen Num: 4
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Publication
- | J:71753
     
First Author: Shimizu T
Year: 2001
Journal: MGI Direct Data Submission
Title: Mapping of Acvr1 to mouse Chromosome 2
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Publication
22508565 | J:194134
First Author: Chakkalakal SA
Year: 2012
Journal: J Bone Miner Res
Title: An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva.
Volume: 27
Issue: 8
Pages: 1746-56
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Publication
26116174 | J:233662
First Author: Noda K
Year: 2016
Journal: Dev Biol
Title: Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice.
Volume: 415
Issue: 2
Pages: 306-313
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Publication
32142668 | J:285841
First Author: Fortin J
Year: 2020
Journal: Cancer Cell
Title: Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
Volume: 37
Issue: 3
Pages: 308-323.e12
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Publication
30833574 | J:273261
First Author: Hoeman CM
Year: 2019
Journal: Nat Commun
Title: ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
Volume: 10
Issue: 1
Pages: 1023
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Publication
32515349 | J:291093
   
First Author: Aykul S
Year: 2020
Journal: Elife
Title: Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop.
Volume: 9
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Publication
33217406 | J:302550
 
First Author: Towler OW
Year: 2021
Journal: Dev Biol
Title: Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP).
Volume: 470
Pages: 136-146
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Publication
18566469 | J:141762
First Author: Rajagopal R
Year: 2008
Journal: Invest Ophthalmol Vis Sci
Title: Functions of the type 1 BMP receptor Acvr1 (Alk2) in lens development: cell proliferation, terminal differentiation, and survival.
Volume: 49
Issue: 11
Pages: 4953-60
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Publication
30519900 | J:325430
First Author: Zhang X
Year: 2019
Journal: J Mol Histol
Title: Distinctive role of ACVR1 in dentin formation: requirement for dentin thickness in molars and prevention of osteodentin formation in incisors of mice.
Volume: 50
Issue: 1
Pages: 43-61
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Publication
21945937 | J:178480
First Author: Kamiya N
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1.
Volume: 414
Issue: 2
Pages: 326-30
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Publication
21504908 | J:174241
First Author: Wiley LA
Year: 2011
Journal: Dis Model Mech
Title: The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.
Volume: 4
Issue: 4
Pages: 484-95
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GXD Expression
GXD Expression
     
Probe: MGI:6166908
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6189726
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Acvr1
Detected: false
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:6166908
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189726
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Acvr1
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6166908
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189726
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Acvr1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6166908
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189726
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Acvr1
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6166908
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189726
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Acvr1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6166908
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189726
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Acvr1
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6166908
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189726
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Acvr1
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
23115204 | J:193724
First Author: Kaplan FS
Year: 2012
Journal: Dis Model Mech
Title: Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis.
Volume: 5
Issue: 6
Pages: 756-62
•
•
•
•
•
Publication
25722188 | J:221139
First Author: Agarwal S
Year: 2015
Journal: Dev Biol
Title: BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints.
Volume: 400
Issue: 2
Pages: 202-9
•
•
•
•
•
Publication
28851540 | J:262510
 
First Author: Brennan TA
Year: 2018
Journal: Bone
Title: Mast cell inhibition as a therapeutic approach in fibrodysplasia ossificans progressiva (FOP).
Volume: 109
Pages: 259-266
•
•
•
•
•
Publication
27881824 | J:239135
First Author: Dey D
Year: 2016
Journal: Sci Transl Med
Title: Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification.
Volume: 8
Issue: 366
Pages: 366ra163
•
•
•
•
•
Publication
33705358 | J:322265
 
First Author: Williams E
Year: 2021
Journal: JCI Insight
Title: Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva.
Volume: 6
Issue: 8
•
•
•
•
•
Publication
35503416 | J:340538
 
First Author: Lees-Shepard JB
Year: 2022
Journal: J Clin Invest
Title: An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice.
Volume: 132
Issue: 12
•
•
•
•
•
Publication
26333933 | J:234069
First Author: Hatsell SJ
Year: 2015
Journal: Sci Transl Med
Title: ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A.
Volume: 7
Issue: 303
Pages: 303ra137
•
•
•
•
•
Publication
30379592 | J:318526
First Author: Haupt J
Year: 2019
Journal: Mol Biol Cell
Title: ACVR1R206H FOP mutation alters mechanosensing and tissue stiffness during heterotopic ossification.
Volume: 30
Issue: 1
Pages: 17-29
•
•
•
•
•
Publication
23572558 | J:204497
First Author: Bagarova J
Year: 2013
Journal: Mol Cell Biol
Title: Constitutively active ALK2 receptor mutants require type II receptor cooperation.
Volume: 33
Issue: 12
Pages: 2413-24
•
•
•
•
•
Publication
25232183 | J:232455
First Author: Peterson JR
Year: 2014
Journal: Stem Cells Transl Med
Title: Targeting of ALK2, a Receptor for Bone Morphogenetic Proteins, Using the Cre/lox System to Enhance Osseous Regeneration by Adipose-Derived Stem Cells.
Volume: 3
Issue: 11
Pages: 1375-80
•
•
•
•
•
Publication
29396429 | J:257905
First Author: Lees-Shepard JB
Year: 2018
Journal: Nat Commun
Title: Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva.
Volume: 9
Issue: 1
Pages: 471
•
•
•
•
•
Publication
36116371 | J:330323
 
First Author: Yamaguchi H
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Enhanced BMP signaling through ALK2 attenuates keratinocyte differentiation.
Volume: 629
Pages: 101-105
•
•
•
•
•
Publication
15531373 | J:95020
First Author: Kishigami S
Year: 2004
Journal: Dev Biol
Title: BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo.
Volume: 276
Issue: 1
Pages: 185-93
•
•
•
•
•
Publication
31571391 | J:302777
First Author: Ishan M
Year: 2020
Journal: Genesis
Title: Increased activity of mesenchymal ALK2-BMP signaling causes posteriorly truncated microglossia and disorganization of lingual tissues.
Volume: 58
Issue: 1
Pages: e23337
•
•
•
•
•
Publication
27029473 | J:294378
First Author: Zhou X
Year: 2016
Journal: J Endocrinol
Title: Normal gonadotropin production and fertility in gonadotrope-specific Bmpr1a knockout mice.
Volume: 229
Issue: 3
Pages: 331-41
•
•
•
•
•
Publication
25413979 | J:233359
First Author: Rigueur D
Year: 2015
Journal: J Bone Miner Res
Title: The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.
Volume: 30
Issue: 4
Pages: 733-41
•
•
•
•
•
Publication
31619522 | J:282968
First Author: Omi M
Year: 2019
Journal: J Biol Chem
Title: Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway.
Volume: 294
Issue: 47
Pages: 17818-17836
•
•
•
•
•
Publication
27048979 | J:251344
 
First Author: Shi C
Year: 2016
Journal: Sci Rep
Title: Deletion of BMP receptor type IB decreased bone mass in association with compromised osteoblastic differentiation of bone marrow mesenchymal progenitors.
Volume: 6
Pages: 24256
•
•
•
•
•
Publication
19733164 | J:154465
First Author: Rajagopal R
Year: 2009
Journal: Dev Biol
Title: The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation.
Volume: 335
Issue: 2
Pages: 305-16
•
•
•
•
•
Publication
23595735 | J:196652
First Author: Choe Y
Year: 2013
Journal: J Neurosci
Title: Bone morphogenic protein signaling is a major determinant of dentate development.
Volume: 33
Issue: 16
Pages: 6766-75
•
•
•
•
•
Publication
30854720 | J:276702
First Author: Hildebrand L
Year: 2019
Journal: Dev Dyn
Title: Limb specific Acvr1-knockout during embryogenesis in mice exhibits great toe malformation as seen in Fibrodysplasia Ossificans Progressiva (FOP).
Volume: 248
Issue: 5
Pages: 396-403
•
•
•
•
•
Publication
34206078 | J:336074
 
First Author: Lyu H
Year: 2021
Journal: Biomedicines
Title: MyD88 Is Not Required for Muscle Injury-Induced Endochondral Heterotopic Ossification in a Mouse Model of Fibrodysplasia Ossificans Progressiva.
Volume: 9
Issue: 6
•
•
•
•
•
Publication
28641928 | J:248982
First Author: Pan H
Year: 2017
Journal: Dev Biol
Title: BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development.
Volume: 429
Issue: 1
Pages: 260-270
•
•
•
•
•
Publication
24680892 | J:212416
First Author: Thomas PS
Year: 2014
Journal: Dev Biol
Title: AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.
Volume: 390
Issue: 2
Pages: 191-207
•
•
•
•
•
Publication
21831921 | J:175828
First Author: Komatsu Y
Year: 2011
Journal: Development
Title: Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry.
Volume: 138
Issue: 18
Pages: 3915-20
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0023572 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0025749 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0025725 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0025695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0025720 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0025481 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_87911 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0026167 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0024946 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0025461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0025592 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0025554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0025680 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0025585 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0026224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
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