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Search results 1 to 100 out of 734 for Ada

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
100 | ADA
Type: gene
Organism: human
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Gene
419194 | ADA
Type: gene
Organism: chicken
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Gene
436919 | ada
Type: gene
Organism: zebrafish
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Gene
717897 | ADA
Type: gene
Organism: macaque, rhesus
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Gene
496434 | ada
Type: gene
Organism: frog, western clawed
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Gene
280712 | ADA
Type: gene
Organism: cattle
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Gene
key_20003 | ADA
Type: gene
Organism: hamster, Chinese
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Gene
key_20573 | ADA
Type: gene
Organism: cat, domestic
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Gene
24165 | Ada
Type: gene
Organism: rat
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Gene
477236 | ADA
Type: gene
Organism: dog, domestic
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Gene
741760 | ADA
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:87916 | Ada
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
108167311 | LOC108167311
Type: gene
Organism: human
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Gene
108167312 | LOC108167312
Type: gene
Organism: human
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Publication
2464855 | J:9609
First Author: Stallings RL
Year: 1989
Journal: Somat Cell Mol Genet
Title: Hypomethylation and ADA gene expression in mouse CAK cells.
Volume: 15
Issue: 1
Pages: 1-11
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GO Term
GO:0140671 | ADA complex
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Publication
6145740 | J:7486
First Author: Siciliano MJ
Year: 1984
Journal: J Hered
Title: Regional assignment of ADA and ITPA to mouse chromosome 2 (C1----ter). A demonstration of the conserved linkage of enzyme and proto-oncogene loci.
Volume: 75
Issue: 3
Pages: 175-80
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Publication
3007037 | J:8227
First Author: Berman EJ
Year: 1986
Journal: Cytogenet Cell Genet
Title: Chromosomal mapping of enzyme loci in the domestic cat: GSR to C2, ADA and ITPA to A3, and LDHA-ACP2 to D1.
Volume: 41
Issue: 2
Pages: 114-20
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Transgene
MGI:3699714 | Tg(Pbsn-TP53*R273H)1Elga
Type: transgene
Organism: mouse, laboratory
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Publication
15287091 | J:92122
First Author: Elgavish A
Year: 2004
Journal: Prostate
Title: Transgenic mouse with human mutant p53 expression in the prostate epithelium.
Volume: 61
Issue: 1
Pages: 26-34
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Allele
Tg(Tcrb31.2.10)#Gifr | MGI:6723899
Name: transgene insertion, Giulia Freer
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
1581309 | -
First Author: Myers LC
Year: 1992
Journal: Biochemistry
Title: Zinc binding by the methylation signaling domain of the Escherichia coli Ada protein.
Volume: 31
Issue: 19
Pages: 4541-7
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Publication
8500619 | -
First Author: Sakashita H
Year: 1993
Journal: FEBS Lett
Title: Folding topology and DNA binding of the N-terminal fragment of Ada protein.
Volume: 323
Issue: 3
Pages: 252-6
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Publication
7670465 | J:26731
First Author: Migchielsen AA
Year: 1995
Journal: Nat Genet
Title: Adenosine-deaminase-deficient mice die perinatally and exhibit liver-cell degeneration, atelectasis and small intestinal cell death.
Volume: 10
Issue: 3
Pages: 279-87
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Publication
7731963 | J:25085
First Author: Wakamiya M
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice.
Volume: 92
Issue: 9
Pages: 3673-7
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Protein Domain
IPR004026 | Ada_DNA_repair_Zn-bd
Type: Domain
Description: The Escherichia coli Ada protein repairs O6-methylguanine residues and methyl phosphotriesters in DNA by direct transfer of the methyl group to a cysteine residue. This domain contains four conserved cysteines that form a zinc binding site [, ]. One of these cysteines is a methyl group acceptor. The methylated domain can then specifically bind to the ada box on a DNA duplex. The zinc binding site is located in the N-terminal region and consists of four beta strands [].
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Publication
10899903 | J:63493
First Author: Blackburn MR
Year: 2000
Journal: J Exp Med
Title: Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction.
Volume: 192
Issue: 2
Pages: 159-70
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Publication
9478961 | J:73418
First Author: Blackburn MR
Year: 1998
Journal: J Biol Chem
Title: Adenosine deaminase-deficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency.
Volume: 273
Issue: 9
Pages: 5093-100
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Publication
7592575 | J:29350
First Author: Blackburn MR
Year: 1995
Journal: J Biol Chem
Title: Tissue-specific rescue suggests that placental adenosine deaminase is important for fetal development in mice.
Volume: 270
Issue: 41
Pages: 23891-4
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Publication
9000171 | J:38437
First Author: Winston JH
Year: 1996
Journal: Somat Cell Mol Genet
Title: An intron 1 regulatory region from the murine adenosine deaminase gene can activate heterologous promoters for ubiquitous expression in transgenic mice.
Volume: 22
Issue: 4
Pages: 261-78
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Publication
8999942 | J:38454
First Author: Shi D
Year: 1997
Journal: J Biol Chem
Title: Diverse genetic regulatory motifs required for murine adenosine deaminase gene expression in the placenta.
Volume: 272
Issue: 4
Pages: 2334-41
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Publication
1820019 | J:740
First Author: Abbott CM
Year: 1991
Journal: Biochem Genet
Title: Adenosine deaminase, Ada, is in mouse chromosome 2H3, and is not allelic with wasted, wst.
Volume: 29
Issue: 11-12
Pages: 537-44
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Publication
8663040 | J:96688
First Author: Blackburn MR
Year: 1996
Journal: J Biol Chem
Title: Metabolic and immunologic consequences of limited adenosine deaminase expression in mice.
Volume: 271
Issue: 25
Pages: 15203-10
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Publication
25538227 | J:234143
First Author: Iriyama T
Year: 2015
Journal: Circulation
Title: Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia.
Volume: 131
Issue: 8
Pages: 730-41
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Author
Ada SR
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Author
Ada S
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Author
Cassado ADA
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Publication
9272950 | J:42444
First Author: Blackburn MR
Year: 1997
Journal: Development
Title: Genetically engineered mice demonstrate that adenosine deaminase is essential for early postimplantation development.
Volume: 124
Issue: 16
Pages: 3089-97
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Publication
10720488 | J:110603
First Author: Xu PA
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Function of murine adenosine deaminase in the gastrointestinal tract.
Volume: 269
Issue: 3
Pages: 749-57
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Publication
21593382 | J:175471
First Author: Ghaemi Oskouie F
Year: 2011
Journal: J Immunol
Title: High levels of adenosine deaminase on dendritic cells promote autoreactive T cell activation and diabetes in nonobese diabetic mice.
Volume: 186
Issue: 12
Pages: 6798-806
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Publication
23392349 | J:313446
First Author: Weng T
Year: 2013
Journal: FASEB J
Title: Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease.
Volume: 27
Issue: 5
Pages: 2013-26
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Publication
16258000 | J:107355
First Author: Chunn JL
Year: 2006
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations.
Volume: 290
Issue: 3
Pages: L579-87
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Publication
30918508 | J:281374
 
First Author: Xu X
Year: 2019
Journal: Front Immunol
Title: Early Enzyme Replacement Therapy Improves Hearing and Immune Defects in Adenosine Deaminase Deficient-Mice.
Volume: 10
Pages: 416
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Publication
11591798 | J:72057
First Author: Chunn JL
Year: 2001
Journal: J Immunol
Title: Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice.
Volume: 167
Issue: 8
Pages: 4676-85
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Publication
34853379 | J:324800
First Author: Moretti FA
Year: 2021
Journal: Sci Rep
Title: Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy.
Volume: 11
Issue: 1
Pages: 23221
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Publication
22833548 | J:191331
First Author: Carbonaro DA
Year: 2012
Journal: Blood
Title: Gene therapy/bone marrow transplantation in ADA-deficient mice: roles of enzyme-replacement therapy and cytoreduction.
Volume: 120
Issue: 18
Pages: 3677-87
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Publication
12855405 | J:95133
First Author: Banerjee SK
Year: 2004
Journal: Am J Respir Cell Mol Biol
Title: Abnormal alveolar development associated with elevated adenine nucleosides.
Volume: 30
Issue: 1
Pages: 38-50
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Publication
16034138 | J:107266
First Author: Chunn JL
Year: 2005
Journal: J Immunol
Title: Adenosine-dependent pulmonary fibrosis in adenosine deaminase-deficient mice.
Volume: 175
Issue: 3
Pages: 1937-46
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Publication
7691243 | J:15401
First Author: Bodine DM
Year: 1993
Journal: Blood
Title: Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells.
Volume: 82
Issue: 7
Pages: 1975-80
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Publication
1618849 | J:1463
First Author: Winston JH
Year: 1992
Journal: J Biol Chem
Title: 5' flanking sequences of the murine adenosine deaminase gene direct expression of a reporter gene to specific prenatal and postnatal tissues in transgenic mice.
Volume: 267
Issue: 19
Pages: 13472-9
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Publication
2432402 | J:8541
First Author: Ingolia DE
Year: 1986
Journal: Mol Cell Biol
Title: Molecular cloning of the murine adenosine deaminase gene from a genetically enriched source: identification and characterization of the promoter region.
Volume: 6
Issue: 12
Pages: 4458-66
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Publication
8474455 | J:4589
First Author: Carroll SM
Year: 1993
Journal: Mol Cell Biol
Title: Localization of a bidirectional DNA replication origin in the native locus and in episomally amplified murine adenosine deaminase loci.
Volume: 13
Issue: 5
Pages: 2971-81
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Publication
7919352 | J:21050
First Author: Chen EH
Year: 1994
Journal: Blood
Title: Hereditary overexpression of adenosine deaminase in erythrocytes: studies in erythroid cell lines and transgenic mice.
Volume: 84
Issue: 7
Pages: 2346-53
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Publication
8566789 | J:30651
First Author: Brickner AG
Year: 1995
Journal: Gene
Title: Identification of a murine homolog of the human adenosine deaminase thymic enhancer.
Volume: 167
Issue: 1-2
Pages: 261-6
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Publication
9089072 | J:39265
First Author: Meng JP
Year: 1997
Journal: J Androl
Title: Characterization and developmental expression of a testis-specific adenosine deaminase mRNA in the mouse.
Volume: 18
Issue: 1
Pages: 88-95
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Publication
9922386 | J:52866
First Author: Brickner AG
Year: 1999
Journal: Mamm Genome
Title: Genomic sequence comparison of the human and mouse adenosine deaminase gene regions.
Volume: 10
Issue: 2
Pages: 95-101
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Publication
10187819 | J:54364
First Author: Xu PA
Year: 1999
Journal: J Biol Chem
Title: Regulation of forestomach-specific expression of the murine adenosine deaminase gene.
Volume: 274
Issue: 15
Pages: 10316-23
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Publication
16835374 | J:140457
First Author: Mortellaro A
Year: 2006
Journal: Blood
Title: Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects.
Volume: 108
Issue: 9
Pages: 2979-88
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Publication
8634299 | J:328859
First Author: Mohamedali KA
Year: 1996
Journal: Biochemistry
Title: Site-directed mutagenesis of active site glutamate-217 in mouse adenosine deaminase.
Volume: 35
Issue: 5
Pages: 1672-80
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Publication
8894685 | J:35811
First Author: Migchielsen AA
Year: 1996
Journal: Hum Mol Genet
Title: Full genetic rescue of adenosine deaminase-deficient mice through introduction of the human gene.
Volume: 5
Issue: 10
Pages: 1523-32
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Publication
2015347 | J:139631
First Author: Knudsen TB
Year: 1991
Journal: Biol Reprod
Title: Ontogeny of adenosine deaminase in the mouse decidua and placenta: immunolocalization and embryo transfer studies.
Volume: 44
Issue: 1
Pages: 171-84
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Publication
16670300 | J:131709
First Author: Van De Wiele CJ
Year: 2006
Journal: J Immunol
Title: Further differentiation of murine double-positive thymocytes is inhibited in adenosine deaminase-deficient murine fetal thymic organ culture.
Volume: 176
Issue: 10
Pages: 5925-33
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Publication
11454903 | J:132588
First Author: Zhong H
Year: 2001
Journal: J Pharmacol Exp Ther
Title: Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice.
Volume: 298
Issue: 2
Pages: 433-40
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Publication
17227950 | J:134751
First Author: Mohsenin A
Year: 2007
Journal: FASEB J
Title: Enhanced CXCL1 production and angiogenesis in adenosine-mediated lung disease.
Volume: 21
Issue: 4
Pages: 1026-36
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Publication
16626672 | J:111146
First Author: Willems L
Year: 2006
Journal: Cardiovasc Res
Title: Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts.
Volume: 71
Issue: 1
Pages: 79-87
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Publication
11067867 | J:115112
First Author: Thompson LF
Year: 2000
Journal: J Clin Invest
Title: Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures.
Volume: 106
Issue: 9
Pages: 1149-57
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Publication
9276742 | J:42700
First Author: Lembertas AV
Year: 1997
Journal: J Clin Invest
Title: Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.
Volume: 100
Issue: 5
Pages: 1240-7
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Publication
12163459 | J:107216
First Author: Van De Wiele CJ
Year: 2002
Journal: J Clin Invest
Title: Adenosine kinase inhibition promotes survival of fetal adenosine deaminase-deficient thymocytes by blocking dATP accumulation.
Volume: 110
Issue: 3
Pages: 395-402
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Publication
8064675 | J:297526
First Author: Alexiou M
Year: 1994
Journal: J Reprod Fertil
Title: Enzymes of purine salvage and catabolism in the mouse preimplantation embryo measured by high performance liquid chromatography.
Volume: 101
Issue: 1
Pages: 151-8
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Publication
10845921 | J:63086
First Author: Apasov S
Year: 2000
Journal: Blood
Title: A(2A) receptor dependent and A(2A) receptor independent effects of extracellular adenosine on murine thymocytes in conditions of adenosine deaminase deficiency.
Volume: 95
Issue: 12
Pages: 3859-67
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Publication
19633200 | J:153849
First Author: Sauer AV
Year: 2009
Journal: Blood
Title: ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency.
Volume: 114
Issue: 15
Pages: 3216-26
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Publication
22184407 | J:181725
First Author: Sauer AV
Year: 2012
Journal: Blood
Title: Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID.
Volume: 119
Issue: 6
Pages: 1428-39
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Publication
25587035 | J:221918
First Author: Sun K
Year: 2015
Journal: Blood
Title: Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity.
Volume: 125
Issue: 10
Pages: 1643-52
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Publication
- | J:14249
 
First Author: Le Tissier P
Year: 1989
Journal: Mouse News Lett
Title: Linkage of adenosine deaminase, Ada.
Volume: 84
Pages: 86
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Publication
- | J:12272
 
First Author: Lalley PA
Year: 1984
Journal: Cytogenet Cell Genet
Title: Comparative gene mapping in the mouse involving genes assigned to human chromosomes 7 and 20. (Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983) Seventh International Workshop on Human Gene Mapping)
Volume: 37 (1-4)
Pages: 514-515 (Abstr.) (399-616)
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Publication
8973343 | J:37134
First Author: Luo C
Year: 1996
Journal: Gene
Title: Normal function of the transcription factor NFAT1 in wasted mice. Chromosome localization of NFAT1 gene.
Volume: 180
Issue: 1-2
Pages: 29-36
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Publication
11435465 | J:110739
First Author: Apasov SG
Year: 2001
Journal: J Clin Invest
Title: Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling.
Volume: 108
Issue: 1
Pages: 131-41
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Publication
14607964 | J:106733
First Author: Aldrich MB
Year: 2003
Journal: J Immunol
Title: Impaired germinal center maturation in adenosine deaminase deficiency.
Volume: 171
Issue: 10
Pages: 5562-70
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Publication
9765260 | J:77790
First Author: Shi D
Year: 1998
Journal: J Biol Chem
Title: Transcription factor AP-2gamma regulates murine adenosine deaminase gene expression during placental development.
Volume: 273
Issue: 42
Pages: 27331-8
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Publication
19858092 | J:158034
First Author: Wen J
Year: 2010
Journal: FASEB J
Title: Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling.
Volume: 24
Issue: 3
Pages: 740-9
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Publication
30641086 | J:276087
 
First Author: Kutryb-Zajac B
Year: 2019
Journal: J Mol Cell Cardiol
Title: Inhibition of LPS-stimulated ecto-adenosine deaminase attenuates endothelial cell activation.
Volume: 128
Pages: 62-76
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Publication
14612417 | J:86566
First Author: Hsu LC
Year: 2003
Journal: Mol Cell Biol
Title: The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription.
Volume: 23
Issue: 23
Pages: 8773-85
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Publication
18340377 | J:135978
First Author: Mi T
Year: 2008
Journal: J Clin Invest
Title: Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling.
Volume: 118
Issue: 4
Pages: 1491-501
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Publication
24614760 | J:216540
First Author: Ning C
Year: 2014
Journal: FASEB J
Title: Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expression.
Volume: 28
Issue: 6
Pages: 2725-35
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Publication
8082833 | J:19658
First Author: Peters J
Year: 1994
Journal: Genet Res
Title: Mapping studies of the distal imprinting region of mouse chromosome 2.
Volume: 63
Issue: 3
Pages: 169-74
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Publication
- | J:2497
First Author: Beechey CV
Year: 1992
Journal: Mouse Genome
Title: Mapping studies of distal chromosome 2 including the imprinting region
Volume: 90
Issue: 3
Pages: 423-24
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Protein Coding Gene
MGP_CAROLIEiJ_G0024622 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026829 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026766 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026804 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026546 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_87916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027252 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026523 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026661 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026627 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026649 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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