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Search results 1 to 100 out of 646 for Adam10

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:7582006
Assay Type: RT-PCR
Annotation Date: 2024-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:7587738
Age: postnatal newborn
Image: 2
Specimen Label: Adam10 CKO
Detected: true
Specimen Num: 2
Publication
First Author: Farber G
Year: 2019
Journal: Angiogenesis
Title: ADAM10 controls the differentiation of the coronary arterial endothelium.
Volume: 22
Issue: 2
Pages: 237-250
Publication
First Author: Faber TW
Year: 2014
Journal: Cell Immunol
Title: ADAM10 is required for SCF-induced mast cell migration.
Volume: 290
Issue: 1
Pages: 80-8
Publication  
First Author: Mizuno S
Year: 2020
Journal: Bone
Title: ADAM10 is indispensable for longitudinal bone growth in mice.
Volume: 134
Pages: 115273
Publication
First Author: Zhang C
Year: 2010
Journal: Dev Dyn
Title: Adam10 is essential for early embryonic cardiovascular development.
Volume: 239
Issue: 10
Pages: 2594-602
Publication
First Author: Caolo V
Year: 2015
Journal: Angiogenesis
Title: ADAM10 and ADAM17 have opposite roles during sprouting angiogenesis.
Volume: 18
Issue: 1
Pages: 13-22
Publication
First Author: Lundgren JL
Year: 2015
Journal: J Neurochem
Title: ADAM10 and BACE1 are localized to synaptic vesicles.
Volume: 135
Issue: 3
Pages: 606-15
Publication
First Author: Chaimowitz NS
Year: 2012
Journal: PLoS One
Title: ADAM10 regulates transcription factor expression required for plasma cell function.
Volume: 7
Issue: 8
Pages: e42694
Publication
First Author: Yoda M
Year: 2011
Journal: Blood
Title: Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis.
Volume: 118
Issue: 26
Pages: 6939-42
Publication
First Author: Marcello E
Year: 2007
Journal: J Neurosci
Title: Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity.
Volume: 27
Issue: 7
Pages: 1682-91
Publication
First Author: Zhu X
Year: 2018
Journal: J Neuroinflammation
Title: Metalloprotease Adam10 suppresses epilepsy through repression of hippocampal neuroinflammation.
Volume: 15
Issue: 1
Pages: 221
Publication
First Author: Tharmarajah G
Year: 2012
Journal: Pigment Cell Melanoma Res
Title: Adam10 haploinsufficiency causes freckle-like macules in Hairless mice.
Volume: 25
Issue: 5
Pages: 555-65
Publication    
First Author: Altmeppen HC
Year: 2015
Journal: Elife
Title: The sheddase ADAM10 is a potent modulator of prion disease.
Volume: 4
Publication
First Author: Moss ML
Year: 2007
Journal: J Biol Chem
Title: The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.
Volume: 282
Issue: 49
Pages: 35712-21
Publication
First Author: Tan Y
Year: 2016
Journal: Biochem Biophys Res Commun
Title: ADAM10 is essential for cranial neural crest-derived maxillofacial bone development.
Volume: 475
Issue: 4
Pages: 308-14
Publication
First Author: Marcello E
Year: 2013
Journal: J Clin Invest
Title: Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease.
Volume: 123
Issue: 6
Pages: 2523-38
Publication
First Author: Malinverno M
Year: 2010
Journal: J Neurosci
Title: Synaptic localization and activity of ADAM10 regulate excitatory synapses through N-cadherin cleavage.
Volume: 30
Issue: 48
Pages: 16343-55
Publication
First Author: Klapproth E
Year: 2022
Journal: Nat Commun
Title: Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Volume: 13
Issue: 1
Pages: 7648
Publication
First Author: Inoshima N
Year: 2012
Journal: J Invest Dermatol
Title: Genetic requirement for ADAM10 in severe Staphylococcus aureus skin infection.
Volume: 132
Issue: 5
Pages: 1513-6
Publication
First Author: Jorissen E
Year: 2010
Journal: J Neurosci
Title: The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex.
Volume: 30
Issue: 14
Pages: 4833-44
Publication
First Author: Glomski K
Year: 2011
Journal: Blood
Title: Deletion of Adam10 in endothelial cells leads to defects in organ-specific vascular structures.
Volume: 118
Issue: 4
Pages: 1163-74
GXD Expression    
Probe: MGI:6166923
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189732
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Adam10
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6166923
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189732
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Adam10
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6166923
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189732
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Adam10
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6166923
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189732
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Adam10
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6166923
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189732
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Adam10
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6166923
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189732
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Adam10
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6166923
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189732
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Adam10
Detected: true
Specimen Num: 7
Publication
First Author: Shah J
Year: 2018
Journal: Cell Rep
Title: A Dock-and-Lock Mechanism Clusters ADAM10 at Cell-Cell Junctions to Promote α-Toxin Cytotoxicity.
Volume: 25
Issue: 8
Pages: 2132-2147.e7
Publication
First Author: Gunner G
Year: 2019
Journal: Nat Neurosci
Title: Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling.
Volume: 22
Issue: 7
Pages: 1075-1088
Publication
First Author: Tian L
Year: 2008
Journal: Int Immunol
Title: ADAM10 is essential for proteolytic activation of Notch during thymocyte development.
Volume: 20
Issue: 9
Pages: 1181-7
Publication
First Author: Mattila SO
Year: 2021
Journal: FASEB J
Title: GPR37 is processed in the N-terminal ectodomain by ADAM10 and furin.
Volume: 35
Issue: 6
Pages: e21654
Publication  
First Author: Alfano DN
Year: 2023
Journal: J Clin Invest
Title: Endothelial ADAM10 utilization defines a molecular pathway of vascular injury in mice with bacterial sepsis.
Volume: 133
Issue: 23
Publication
First Author: Li B
Year: 2020
Journal: J Pathol
Title: ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling.
Volume: 252
Issue: 3
Pages: 274-289
Publication
First Author: Muraguchi T
Year: 2007
Journal: Nat Neurosci
Title: RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity.
Volume: 10
Issue: 7
Pages: 838-45
Publication
First Author: Cooley LF
Year: 2015
Journal: PLoS One
Title: Increased B Cell ADAM10 in Allergic Patients and Th2 Prone Mice.
Volume: 10
Issue: 5
Pages: e0124331
Publication
First Author: Bozkulak EC
Year: 2009
Journal: Mol Cell Biol
Title: Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.
Volume: 29
Issue: 21
Pages: 5679-95
Publication
First Author: Esteve P
Year: 2011
Journal: Nat Neurosci
Title: SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.
Volume: 14
Issue: 5
Pages: 562-9
Publication
First Author: Inoshima I
Year: 2011
Journal: Nat Med
Title: A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice.
Volume: 17
Issue: 10
Pages: 1310-4
Publication
First Author: Vezzoli E
Year: 2019
Journal: J Clin Invest
Title: Inhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's disease.
Volume: 129
Issue: 6
Pages: 2390-2403
Publication
First Author: Kuhn PH
Year: 2010
Journal: EMBO J
Title: ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.
Volume: 29
Issue: 17
Pages: 3020-32
Publication
First Author: Schmitt U
Year: 2006
Journal: Behav Brain Res
Title: Over-expression of two different forms of the alpha-secretase ADAM10 affects learning and memory in mice.
Volume: 175
Issue: 2
Pages: 278-84
Publication
First Author: Herzog C
Year: 2014
Journal: J Biol Chem
Title: ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A.
Volume: 289
Issue: 19
Pages: 13308-22
Publication
First Author: Ikeda A
Year: 2019
Journal: Sci Rep
Title: ADAM10 is Expressed by Ameloblasts, Cleaves the RELT TNF Receptor Extracellular Domain and Facilitates Enamel Development.
Volume: 9
Issue: 1
Pages: 14086
Publication
First Author: Solanas G
Year: 2011
Journal: Nat Cell Biol
Title: Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling.
Volume: 13
Issue: 9
Pages: 1100-7
Publication
First Author: Atapattu L
Year: 2016
Journal: J Exp Med
Title: An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth.
Volume: 213
Issue: 9
Pages: 1741-57
Publication
First Author: Schulte M
Year: 2007
Journal: Cell Death Differ
Title: ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.
Volume: 14
Issue: 5
Pages: 1040-9
Publication
First Author: Fernandez JW
Year: 2010
Journal: FEBS Lett
Title: EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP.
Volume: 584
Issue: 19
Pages: 4259-67
Publication
First Author: Brummer T
Year: 2018
Journal: FASEB J
Title: The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation.
Volume: 32
Issue: 7
Pages: 3560-3573
Publication    
First Author: Caolo V
Year: 2020
Journal: Elife
Title: Shear stress activates ADAM10 sheddase to regulate Notch1 via the Piezo1 force sensor in endothelial cells.
Volume: 9
Publication
First Author: Wang X
Year: 2018
Journal: J Mol Cell Biol
Title: α-secretase ADAM10 physically interacts with β-secretase BACE1 in neurons and regulates CHL1 proteolysis.
Volume: 10
Issue: 5
Pages: 411-422
Publication  
First Author: Zhang X
Year: 2021
Journal: Biochem Biophys Res Commun
Title: ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase.
Volume: 537
Pages: 15-21
Publication
First Author: Weber S
Year: 2011
Journal: Development
Title: The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling.
Volume: 138
Issue: 3
Pages: 495-505
Publication
First Author: Reiss K
Year: 2005
Journal: EMBO J
Title: ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling.
Volume: 24
Issue: 4
Pages: 742-52
Publication
First Author: Cozzolino F
Year: 2021
Journal: Hum Mol Genet
Title: ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease.
Volume: 30
Issue: 13
Pages: 1175-1187
Publication
First Author: Meyer zu Horste G
Year: 2015
Journal: J Neuropathol Exp Neurol
Title: Neuronal ADAM10 Promotes Outgrowth of Small-Caliber Myelinated Axons in the Peripheral Nervous System.
Volume: 74
Issue: 11
Pages: 1077-85
Publication
First Author: Zhuang J
Year: 2015
Journal: Gene
Title: Effects of ADAM10 deletion on Notch-1 signaling pathway and neuronal maintenance in adult mouse brain.
Volume: 555
Issue: 2
Pages: 150-8
Publication
First Author: Zbodakova O
Year: 2021
Journal: Sci Rep
Title: ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis.
Volume: 11
Issue: 1
Pages: 11414
Publication
First Author: Pruessmeyer J
Year: 2014
Journal: Blood
Title: Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space.
Volume: 123
Issue: 26
Pages: 4077-88
Publication
First Author: Lownik JC
Year: 2019
Journal: J Immunol
Title: B Cell ADAM10 Controls Murine Lupus Progression through Regulation of the ICOS:ICOS Ligand Axis.
Volume: 202
Issue: 3
Pages: 664-674
Publication
First Author: Padro CJ
Year: 2013
Journal: J Immunol
Title: Adrenergic regulation of IgE involves modulation of CD23 and ADAM10 expression on exosomes.
Volume: 191
Issue: 11
Pages: 5383-97
Publication
First Author: Cissé MA
Year: 2005
Journal: J Biol Chem
Title: The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity.
Volume: 280
Issue: 49
Pages: 40624-31
Publication
First Author: Shackleton B
Year: 2016
Journal: Fluids Barriers CNS
Title: Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
Volume: 13
Issue: 1
Pages: 14
Publication
First Author: Gibb DR
Year: 2010
Journal: J Exp Med
Title: ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.
Volume: 207
Issue: 3
Pages: 623-35
Publication
First Author: Fujita K
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen.
Volume: 116
Issue: 29
Pages: 14714-14723
Publication
First Author: Sahin U
Year: 2004
Journal: J Cell Biol
Title: Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.
Volume: 164
Issue: 5
Pages: 769-79
Publication
First Author: Brennaman LH
Year: 2014
Journal: J Neurochem
Title: EphrinA/EphA-induced ectodomain shedding of neural cell adhesion molecule regulates growth cone repulsion through ADAM10 metalloprotease.
Volume: 128
Issue: 2
Pages: 267-79
Publication
First Author: Prox J
Year: 2013
Journal: J Neurosci
Title: Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions.
Volume: 33
Issue: 32
Pages: 12915-28, 12928a
Publication  
First Author: Jang BG
Year: 2022
Journal: Cells
Title: 2,4-Diacetylphloroglucinol Reduces Beta-Amyloid Production and Secretion by Regulating ADAM10 and Intracellular Trafficking in Cellular and Animal Models of Alzheimer's Disease.
Volume: 11
Issue: 16
Publication  
First Author: Diener N
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone.
Volume: 118
Issue: 38
Publication
First Author: Wang YM
Year: 2019
Journal: Cell Death Differ
Title: MicroRNA-197 controls ADAM10 expression to mediate MeCP2's role in the differentiation of neuronal progenitors.
Volume: 26
Issue: 10
Pages: 1863-1879
Publication
First Author: Maretzky T
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.
Volume: 102
Issue: 26
Pages: 9182-7
Publication
First Author: Franzke CW
Year: 2009
Journal: J Biol Chem
Title: Shedding of collagen XVII/BP180 in skin depends on both ADAM10 and ADAM9.
Volume: 284
Issue: 35
Pages: 23386-96
Publication
First Author: Guo Q
Year: 2015
Journal: J Am Soc Nephrol
Title: Adam10 mediates the choice between principal cells and intercalated cells in the kidney.
Volume: 26
Issue: 1
Pages: 149-59
Publication  
First Author: Yao Y
Year: 2019
Journal: Front Immunol
Title: Platelet-Derived Exosomal MicroRNA-25-3p Inhibits Coronary Vascular Endothelial Cell Inflammation Through Adam10 via the NF-κB Signaling Pathway in ApoE-/- Mice.
Volume: 10
Pages: 2205
Publication    
First Author: Kuhn PH
Year: 2016
Journal: Elife
Title: Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function.
Volume: 5
Publication
First Author: Lizama C
Year: 2011
Journal: Biochim Biophys Acta
Title: Etoposide induces apoptosis and upregulation of TACE/ADAM17 and ADAM10 in an in vitro male germ cell line model.
Volume: 1813
Issue: 1
Pages: 120-8
Publication
First Author: Marcinkiewicz M
Year: 2000
Journal: J Neurochem
Title: Coordinated expression of beta-amyloid precursor protein and the putative beta-secretase BACE and alpha-secretase ADAM10 in mouse and human brain.
Volume: 75
Issue: 5
Pages: 2133-43
Publication
First Author: Damle SR
Year: 2018
Journal: Allergy
Title: ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production.
Volume: 73
Issue: 1
Pages: 125-136
Publication  
First Author: van der Vorst EPC
Year: 2023
Journal: Front Cardiovasc Med
Title: Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice.
Volume: 10
Pages: 974918
Publication
First Author: Pan D
Year: 1997
Journal: Cell
Title: Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis.
Volume: 90
Issue: 2
Pages: 271-80
Publication
First Author: Kim J
Year: 2010
Journal: J Biol Chem
Title: Activity-dependent alpha-cleavage of nectin-1 is mediated by a disintegrin and metalloprotease 10 (ADAM10).
Volume: 285
Issue: 30
Pages: 22919-26
Publication
First Author: Lemieux GA
Year: 2007
Journal: J Biol Chem
Title: The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.
Volume: 282
Issue: 20
Pages: 14836-44
Publication
First Author: Farber G
Year: 2018
Journal: Angiogenesis
Title: Glomerular endothelial cell maturation depends on ADAM10, a key regulator of Notch signaling.
Volume: 21
Issue: 2
Pages: 335-347
Publication
First Author: Bloch L
Year: 2009
Journal: FEBS Lett
Title: Klotho is a substrate for alpha-, beta- and gamma-secretase.
Volume: 583
Issue: 19
Pages: 3221-4
Publication
First Author: Yang Z
Year: 2017
Journal: Cereb Cortex
Title: ADAM10-Initiated Release of Notch Intracellular Domain Regulates Microtubule Stability and Radial Migration of Cortical Neurons.
Volume: 27
Issue: 2
Pages: 919-932
Publication  
First Author: Romi E
Year: 2014
Journal: Nat Commun
Title: ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.
Volume: 5
Pages: 4058
Publication
First Author: Cong R
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: A disintegrin and metalloprotease 10 activity sheds the ectodomain of the amyloid precursor-like protein 2 and regulates protein expression in proximal tubule cells.
Volume: 300
Issue: 6
Pages: C1366-74
GXD Expression    
Probe: MGI:7582007
Assay Type: RT-PCR
Annotation Date: 2024-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Stage: TS27
Assay Id: MGI:7587739
Age: postnatal newborn
Image: 2
Specimen Label: Adam10 CKO
Detected: true
Specimen Num: 2
Publication
First Author: Hammad H
Year: 2017
Journal: Nat Immunol
Title: Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10.
Volume: 18
Issue: 3
Pages: 313-320
Publication
First Author: Tousseyn T
Year: 2009
Journal: J Biol Chem
Title: ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase.
Volume: 284
Issue: 17
Pages: 11738-47