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Search results 1 to 100 out of 452 for Adam17

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0.022s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Kommaddi RP
Year: 2011
Journal: FASEB J
Title: Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling.
Volume: 25
Issue: 6
Pages: 2061-70
Publication
First Author: Wang Y
Year: 2013
Journal: Biochim Biophys Acta
Title: ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils.
Volume: 1833
Issue: 3
Pages: 680-5
Publication
First Author: Arndt PG
Year: 2011
Journal: PLoS One
Title: Leukocyte ADAM17 regulates acute pulmonary inflammation.
Volume: 6
Issue: 5
Pages: e19938
Publication
First Author: Sel S
Year: 2012
Journal: Ann Anat
Title: Expression analysis of ADAM17 during mouse eye development.
Volume: 194
Issue: 4
Pages: 334-8
Publication
First Author: Saad MI
Year: 2020
Journal: Carcinogenesis
Title: The ADAM17 protease promotes tobacco smoke carcinogen-induced lung tumorigenesis.
Volume: 41
Issue: 4
Pages: 527-538
Publication  
First Author: Sommer A
Year: 2016
Journal: Nat Commun
Title: Phosphatidylserine exposure is required for ADAM17 sheddase function.
Volume: 7
Pages: 11523
Publication
First Author: Groot AJ
Year: 2013
Journal: J Invest Dermatol
Title: Epidermal ADAM17 is dispensable for notch activation.
Volume: 133
Issue: 9
Pages: 2286-8
Publication
First Author: Wang Y
Year: 2009
Journal: J Immunol
Title: Regulation of mature ADAM17 by redox agents for L-selectin shedding.
Volume: 182
Issue: 4
Pages: 2449-57
Publication
First Author: West MA
Year: 2008
Journal: J Cell Biol
Title: TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent.
Volume: 182
Issue: 5
Pages: 993-1005
Publication
First Author: Mukerjee S
Year: 2019
Journal: Hypertension
Title: ACE2 and ADAM17 Interaction Regulates the Activity of Presympathetic Neurons.
Volume: 74
Issue: 5
Pages: 1181-1191
Publication
First Author: Schmidt S
Year: 2018
Journal: J Exp Med
Title: ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.
Volume: 215
Issue: 4
Pages: 1205-1225
Publication
First Author: Becker AM
Year: 2015
Journal: Exp Hematol
Title: ADAM17 limits the expression of CSF1R on murine hematopoietic progenitors.
Volume: 43
Issue: 1
Pages: 44-52.e1-3
Publication  
First Author: Kefaloyianni E
Year: 2016
Journal: JCI Insight
Title: ADAM17 substrate release in proximal tubule drives kidney fibrosis.
Volume: 1
Issue: 13
Publication
First Author: Hassemer EL
Year: 2013
Journal: Invest Ophthalmol Vis Sci
Title: ADAM17 transactivates EGFR signaling during embryonic eyelid closure.
Volume: 54
Issue: 1
Pages: 132-40
Publication
First Author: Nicolaou A
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in Mice.
Volume: 37
Issue: 2
Pages: 247-257
Publication
First Author: Hall KC
Year: 2013
Journal: Mol Cell Biol
Title: ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes.
Volume: 33
Issue: 16
Pages: 3077-90
Publication
First Author: Li Y
Year: 2006
Journal: Blood
Title: ADAM17 deficiency by mature neutrophils has differential effects on L-selectin shedding.
Volume: 108
Issue: 7
Pages: 2275-9
Publication
First Author: Aktas B
Year: 2005
Journal: J Biol Chem
Title: Aspirin induces platelet receptor shedding via ADAM17 (TACE).
Volume: 280
Issue: 48
Pages: 39716-22
Publication
First Author: Long C
Year: 2012
Journal: J Leukoc Biol
Title: ADAM17 activation in circulating neutrophils following bacterial challenge impairs their recruitment.
Volume: 92
Issue: 3
Pages: 667-72
Publication
First Author: Bozkulak EC
Year: 2009
Journal: Mol Cell Biol
Title: Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.
Volume: 29
Issue: 21
Pages: 5679-95
Publication
First Author: Chalaris A
Year: 2010
Journal: J Exp Med
Title: Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
Volume: 207
Issue: 8
Pages: 1617-24
Publication
First Author: Kawai T
Year: 2017
Journal: Hypertension
Title: Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile-Induced Abdominal Aortic Aneurysm.
Volume: 70
Issue: 5
Pages: 959-963
Publication
First Author: Suzuki S
Year: 2020
Journal: Am J Physiol Lung Cell Mol Physiol
Title: ADAM17 protects against elastase-induced emphysema by suppressing CD62L+ leukocyte infiltration in mice.
Volume: 318
Issue: 6
Pages: L1172-L1182
Publication
First Author: Cabron AS
Year: 2018
Journal: J Immunol
Title: Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells.
Volume: 201
Issue: 10
Pages: 3106-3118
Publication
First Author: Li Y
Year: 2018
Journal: Exp Cell Res
Title: ADAM17 promotes cell migration and invasion through the integrin β1 pathway in hepatocellular carcinoma.
Volume: 370
Issue: 2
Pages: 373-382
Publication
First Author: Canault M
Year: 2010
Journal: PLoS One
Title: The lack of ADAM17 activity during embryonic development causes hemorrhage and impairs vessel formation.
Volume: 5
Issue: 10
Pages: e13433
Publication
First Author: Schwarz J
Year: 2014
Journal: J Biol Chem
Title: Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding.
Volume: 289
Issue: 5
Pages: 3080-93
Publication  
First Author: Gutsaeva DR
Year: 2020
Journal: Int J Mol Sci
Title: Inactivation of Endothelial ADAM17 Reduces Retinal Ischemia-Reperfusion Induced Neuronal and Vascular Damage.
Volume: 21
Issue: 15
Publication
First Author: Weskamp G
Year: 2010
Journal: Circ Res
Title: Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytes.
Volume: 106
Issue: 5
Pages: 932-40
Publication  
First Author: Zhang X
Year: 2021
Journal: Biochem Biophys Res Commun
Title: ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase.
Volume: 537
Pages: 15-21
Publication
First Author: Tang B
Year: 2020
Journal: FASEB J
Title: Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Volume: 34
Issue: 4
Pages: 4956-4969
Publication
First Author: Long C
Year: 2010
Journal: J Leukoc Biol
Title: In vivo role of leukocyte ADAM17 in the inflammatory and host responses during E. coli-mediated peritonitis.
Volume: 87
Issue: 6
Pages: 1097-101
Publication
First Author: Lownik JC
Year: 2020
Journal: Biochem Biophys Res Commun
Title: B cell ADAM17 controls T cell independent humoral immune responses through regulation of TACI and CD138.
Volume: 522
Issue: 2
Pages: 442-447
Publication
First Author: Bell JH
Year: 2007
Journal: J Leukoc Biol
Title: Role of ADAM17 in the ectodomain shedding of TNF-alpha and its receptors by neutrophils and macrophages.
Volume: 82
Issue: 1
Pages: 173-6
Publication
First Author: Murthy A
Year: 2012
Journal: Immunity
Title: Notch activation by the metalloproteinase ADAM17 regulates myeloproliferation and atopic barrier immunity by suppressing epithelial cytokine synthesis.
Volume: 36
Issue: 1
Pages: 105-19
Publication
First Author: Wang Y
Year: 2010
Journal: J Immunol
Title: ADAM17 activity and other mechanisms of soluble L-selectin production during death receptor-induced leukocyte apoptosis.
Volume: 184
Issue: 8
Pages: 4447-54
Publication
First Author: Ford BM
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice.
Volume: 305
Issue: 3
Pages: F323-32
Publication
First Author: Rabie T
Year: 2005
Journal: J Biol Chem
Title: Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein V.
Volume: 280
Issue: 15
Pages: 14462-8
Publication  
First Author: Saad MI
Year: 2019
Journal: EMBO Mol Med
Title: ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.
Volume: 11
Issue: 4
Publication
First Author: Franzke CW
Year: 2012
Journal: J Exp Med
Title: Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.
Volume: 209
Issue: 6
Pages: 1105-19
Publication
First Author: Holdt LM
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Increased ADAM17 mRNA expression and activity is associated with atherosclerosis resistance in LDL-receptor deficient mice.
Volume: 28
Issue: 6
Pages: 1097-103
Publication
First Author: Hall KC
Year: 2012
Journal: PLoS One
Title: Interleukin-1 stimulates ADAM17 through a mechanism independent of its cytoplasmic domain or phosphorylation at threonine 735.
Volume: 7
Issue: 2
Pages: e31600
Publication
First Author: Pruessmeyer J
Year: 2014
Journal: Blood
Title: Leukocytes require ADAM10 but not ADAM17 for their migration and inflammatory recruitment into the alveolar space.
Volume: 123
Issue: 26
Pages: 4077-88
Publication
First Author: Li X
Year: 2017
Journal: J Cell Sci
Title: Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
Volume: 130
Issue: 5
Pages: 868-878
Publication
First Author: Weskamp G
Year: 2020
Journal: J Biol Chem
Title: ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Volume: 295
Issue: 13
Pages: 4350-4358
Publication
First Author: Gravano DM
Year: 2010
Journal: PLoS One
Title: ADAM17 deletion in thymic epithelial cells alters aire expression without affecting T cell developmental progression.
Volume: 5
Issue: 10
Pages: e13528
Publication
First Author: Driscoll WS
Year: 2013
Journal: Circ Res
Title: Macrophage ADAM17 deficiency augments CD36-dependent apoptotic cell uptake and the linked anti-inflammatory phenotype.
Volume: 113
Issue: 1
Pages: 52-61
Publication
First Author: Le Gall SM
Year: 2010
Journal: J Cell Sci
Title: ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.
Volume: 123
Issue: Pt 22
Pages: 3913-22
Publication
First Author: Sahin U
Year: 2004
Journal: J Cell Biol
Title: Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands.
Volume: 164
Issue: 5
Pages: 769-79
Publication
First Author: Takayanagi T
Year: 2016
Journal: Hypertension
Title: Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II.
Volume: 68
Issue: 4
Pages: 949-955
Publication
First Author: Li Q
Year: 2013
Journal: PLoS One
Title: ADAM17 is critical for multipolar exit and radial migration of neuronal intermediate progenitor cells in mice cerebral cortex.
Volume: 8
Issue: 6
Pages: e65703
Publication    
First Author: Lora J
Year: 2021
Journal: J Biol Chem
Title: Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
Pages: 100733
Publication
First Author: Li N
Year: 2007
Journal: J Immunol
Title: Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development.
Volume: 178
Issue: 7
Pages: 4214-21
Publication
First Author: Kawasaki K
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.
Volume: 111
Issue: 21
Pages: 7723-8
Publication      
First Author: Tang J
Year: 2018
Journal: Mol Cell Biol
Title: Neutrophil and macrophage cell surface CSF-1 shed by ADAM17 drives mouse macrophage proliferation in acute and chronic inflammation.
Publication
First Author: Mishra HK
Year: 2016
Journal: J Leukoc Biol
Title: Targeting ADAM17 in leukocytes increases neutrophil recruitment and reduces bacterial spread during polymicrobial sepsis.
Volume: 100
Issue: 5
Pages: 999-1004
Publication
First Author: Wilson CL
Year: 2013
Journal: Mech Dev
Title: Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.
Volume: 130
Issue: 4-5
Pages: 272-89
Publication
First Author: Beck Gooz M
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease.
Volume: 307
Issue: 5
Pages: F551-9
Publication
First Author: Kawaguchi N
Year: 2007
Journal: J Cell Sci
Title: Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.
Volume: 120
Issue: Pt 6
Pages: 943-52
Publication
First Author: Yan I
Year: 2016
Journal: J Leukoc Biol
Title: ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses.
Volume: 99
Issue: 5
Pages: 749-60
Publication
First Author: DeBerge MP
Year: 2015
Journal: J Leukoc Biol
Title: Shedding of TNF receptor 2 by effector CD8⁺ T cells by ADAM17 is important for regulating TNF-α availability during influenza infection.
Volume: 98
Issue: 3
Pages: 423-34
Publication
First Author: Folgosa L
Year: 2013
Journal: J Immunol
Title: Disturbed follicular architecture in B cell A disintegrin and metalloproteinase (ADAM)10 knockouts is mediated by compensatory increases in ADAM17 and TNF-α shedding.
Volume: 191
Issue: 12
Pages: 5951-8
Protein
Organism: Mus musculus
Length: 827  
Fragment?: false
Protein
Organism: Mus musculus
Length: 827  
Fragment?: false
Publication
First Author: Lorenzen I
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain.
Volume: 415
Issue: 2
Pages: 330-6
Publication  
First Author: Maretzky T
Year: 2011
Journal: Nat Commun
Title: Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17.
Volume: 2
Pages: 229
Publication  
First Author: Veit M
Year: 2019
Journal: Life Sci Alliance
Title: Mutagenesis of the ADAM17-phosphatidylserine-binding motif leads to embryonic lethality in mice.
Volume: 2
Issue: 5
Publication
First Author: Lorenzen I
Year: 2012
Journal: FEBS Lett
Title: The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II.
Volume: 586
Issue: 8
Pages: 1093-100
Publication
First Author: Sahin U
Year: 2007
Journal: FEBS Lett
Title: Ectodomain shedding of the EGF-receptor ligand epigen is mediated by ADAM17.
Volume: 581
Issue: 1
Pages: 41-4
Publication
First Author: Fan D
Year: 2015
Journal: Circ Heart Fail
Title: Cardiomyocyte A Disintegrin And Metalloproteinase 17 (ADAM17) Is Essential in Post-Myocardial Infarction Repair by Regulating Angiogenesis.
Volume: 8
Issue: 5
Pages: 970-9
Publication
First Author: Feng Y
Year: 2015
Journal: Mol Cell Biol
Title: Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.
Volume: 35
Issue: 21
Pages: 3604-21
Publication
First Author: Quarta S
Year: 2019
Journal: FASEB J
Title: Impaired mechanical, heat, and cold nociception in a murine model of genetic TACE/ADAM17 knockdown.
Volume: 33
Issue: 3
Pages: 4418-4431
Publication
First Author: Hassemer EL
Year: 2010
Journal: Genetics
Title: The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17.
Volume: 185
Issue: 1
Pages: 245-55
Publication
First Author: Dreymueller D
Year: 2014
Journal: J Immunol
Title: Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Volume: 192
Issue: 2
Pages: 722-31
Publication  
First Author: Shen M
Year: 2017
Journal: J Mol Cell Cardiol
Title: Loss of smooth muscle cell disintegrin and metalloproteinase 17 transiently suppresses angiotensin II-induced hypertension and end-organ damage.
Volume: 103
Pages: 11-21
Publication
First Author: Otulakowski G
Year: 2014
Journal: J Physiol
Title: Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17.
Volume: 592
Issue: 20
Pages: 4507-21
Publication    
First Author: Künzel U
Year: 2018
Journal: Elife
Title: FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.
Volume: 7
Publication  
First Author: Sommer D
Year: 2019
Journal: Brain Behav Immun
Title: ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury.
Volume: 80
Pages: 129-145
Publication  
First Author: Romi E
Year: 2014
Journal: Nat Commun
Title: ADAM metalloproteases promote a developmental switch in responsiveness to the axonal repellant Sema3A.
Volume: 5
Pages: 4058
Publication
First Author: Fan D
Year: 2016
Journal: Hypertension
Title: A Disintegrin and Metalloprotease-17 Regulates Pressure Overload-Induced Myocardial Hypertrophy and Dysfunction Through Proteolytic Processing of Integrin β1.
Volume: 68
Issue: 4
Pages: 937-48
Publication
First Author: Ardito CM
Year: 2012
Journal: Cancer Cell
Title: EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
Volume: 22
Issue: 3
Pages: 304-17
Publication  
First Author: Shimoda M
Year: 2016
Journal: EBioMedicine
Title: Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.
Volume: 5
Pages: 114-24
Publication
First Author: Sternlicht MD
Year: 2005
Journal: Development
Title: Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin.
Volume: 132
Issue: 17
Pages: 3923-33
Publication
First Author: Adrain C
Year: 2012
Journal: Science
Title: Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Volume: 335
Issue: 6065
Pages: 225-8
Publication
First Author: Lownik JC
Year: 2019
Journal: Biochem Biophys Res Commun
Title: A Disintegrin and Metalloproteinase 17 is required for ILC2 responses to IL-33.
Volume: 512
Issue: 4
Pages: 723-728
Publication
First Author: Dierker T
Year: 2009
Journal: J Biol Chem
Title: Heparan sulfate-modulated, metalloprotease-mediated sonic hedgehog release from producing cells.
Volume: 284
Issue: 12
Pages: 8013-22
Publication
First Author: Cerretti DP
Year: 1999
Journal: Cytokine
Title: Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25.
Volume: 11
Issue: 8
Pages: 541-51
Publication    
First Author: Capone C
Year: 2016
Journal: Elife
Title: Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics.
Volume: 5
Publication  
First Author: Shipman WD
Year: 2018
Journal: Sci Transl Med
Title: A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity.
Volume: 10
Issue: 454
Publication
First Author: Zhu L
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury.
Volume: 104
Issue: 5
Pages: 1621-6
Publication
First Author: Horiuchi K
Year: 2007
Journal: Mol Biol Cell
Title: Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.
Volume: 18
Issue: 1
Pages: 176-88
Publication
First Author: Gupte M
Year: 2008
Journal: Am J Physiol Regul Integr Comp Physiol
Title: ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet.
Volume: 295
Issue: 3
Pages: R781-8
Publication
First Author: Flynn CM
Year: 2020
Journal: Sci Rep
Title: Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro.
Volume: 10
Issue: 1
Pages: 21612
Publication
First Author: Mohammed RN
Year: 2019
Journal: Sci Rep
Title: ADAM17-dependent proteolysis of L-selectin promotes early clonal expansion of cytotoxic T cells.
Volume: 9
Issue: 1
Pages: 5487
Publication
First Author: Fuchslocher Chico J
Year: 2018
Journal: Oncotarget
Title: The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis.
Volume: 9
Issue: 16
Pages: 12941-12958
Publication
First Author: Gorovoy M
Year: 2010
Journal: J Leukoc Biol
Title: Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages.
Volume: 88
Issue: 4
Pages: 769-78
Publication
First Author: van Erp S
Year: 2015
Journal: Dev Cell
Title: Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases.
Volume: 35
Issue: 5
Pages: 537-52