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Search results 1 to 100 out of 516 for Adar

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
103 | ADAR
Type: gene
Organism: human
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Gene
100493195 | adar
Type: gene
Organism: frog, western clawed
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Gene
81635 | Adar
Type: gene
Organism: rat
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Gene
457349 | ADAR
Type: gene
Organism: chimpanzee
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Gene
505134 | ADAR
Type: gene
Organism: cattle
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Gene
100855668 | ADAR
Type: gene
Organism: dog, domestic
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Gene
769675 | ADAR
Type: gene
Organism: chicken
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Gene
58119 | adar
Type: gene
Organism: zebrafish
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Gene
718759 | ADAR
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1889575 | Adar
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
37502436 | J:354079
First Author: Adar T
Year: 2023
Journal: Clin Exp Hepatol
Title: Increased hepatic Akt phosphorylation alleviated glucose intolerance and improved liver function in leptin-deficient mice.
Volume: 9
Issue: 2
Pages: 164-171
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Publication
31941663 | J:288804
First Author: Costa Cruz PH
Year: 2020
Journal: RNA
Title: A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing.
Volume: 26
Issue: 4
Pages: 454-469
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Publication
31956894 | J:292357
First Author: Bajad P
Year: 2020
Journal: Nucleic Acids Res
Title: An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype.
Volume: 48
Issue: 6
Pages: 3286-3303
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Publication
24025532 | J:303009
First Author: Stulić M
Year: 2013
Journal: RNA Biol
Title: Spatio-temporal profiling of Filamin A RNA-editing reveals ADAR preferences and high editing levels outside neuronal tissues.
Volume: 10
Issue: 10
Pages: 1611-7
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Publication
36457126 | J:332992
First Author: Guo X
Year: 2022
Journal: J Neuroinflammation
Title: An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain.
Volume: 19
Issue: 1
Pages: 285
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Protein
Q4FJS9
Organism: Mus musculus/domesticus
Length: 1152  
Fragment?: false
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Allele
Adar<em1Qwan> | MGI:7432329
Name: adenosine deaminase, RNA-specific; endonuclease-mediated mutation 1, Qingde Wang
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
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Publication
11099415 | J:65981
First Author: Wang Q
Year: 2000
Journal: Science
Title: Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis.
Volume: 290
Issue: 5497
Pages: 1765-8
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Publication
14613934 | J:87714
First Author: Wang Q
Year: 2004
Journal: J Biol Chem
Title: Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene.
Volume: 279
Issue: 6
Pages: 4952-61
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Publication
38935501 | J:353061
First Author: Gan WL
Year: 2024
Journal: Cell Rep
Title: Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver.
Volume: 43
Issue: 7
Pages: 114400
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Publication
36975179 | J:338600
First Author: Liang Z
Year: 2023
Journal: EMBO Rep
Title: The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant.
Volume: 24
Issue: 5
Pages: e55835
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Publication
37421629 | J:354327
First Author: Guo X
Year: 2023
Journal: Cell Rep
Title: ADAR1 Zα domain P195A mutation activates the MDA5-dependent RNA-sensing signaling pathway in brain without decreasing overall RNA editing.
Volume: 42
Issue: 7
Pages: 112733
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Publication
26275108 | J:226177
First Author: Liddicoat BJ
Year: 2015
Journal: Science
Title: RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself.
Volume: 349
Issue: 6252
Pages: 1115-20
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Publication
17369310 | J:189989
First Author: Ohlson J
Year: 2007
Journal: RNA
Title: Editing modifies the GABA(A) receptor subunit alpha3.
Volume: 13
Issue: 5
Pages: 698-703
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Publication
37290963 | J:342175
First Author: Liang Z
Year: 2023
Journal: RNA
Title: Generation of a new Adar1p150 (-/-) mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis.
Volume: 29
Issue: 9
Pages: 1325-1338
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Publication
26588779 | J:234577
First Author: Pestal K
Year: 2015
Journal: Immunity
Title: Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development.
Volume: 43
Issue: 5
Pages: 933-44
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Publication
34343497 | J:308678
     
First Author: Maurano M
Year: 2021
Journal: Immunity
Title: Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1.
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Publication
28395340 | J:243912
First Author: Snyder EM
Year: 2017
Journal: Biol Reprod
Title: Testicular adenosine to inosine RNA editing in the mouse is mediated by ADARB1.
Volume: 96
Issue: 1
Pages: 244-253
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Publication
22310477 | J:186578
First Author: Vesely C
Year: 2012
Journal: Genome Res
Title: Adenosine deaminases that act on RNA induce reproducible changes in abundance and sequence of embryonic miRNAs.
Volume: 22
Issue: 8
Pages: 1468-76
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Publication
25456137 | J:265968
First Author: Mannion NM
Year: 2014
Journal: Cell Rep
Title: The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Volume: 9
Issue: 4
Pages: 1482-94
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Publication
28355180 | J:243505
First Author: AktaÅŸ T
Year: 2017
Journal: Nature
Title: DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.
Volume: 544
Issue: 7648
Pages: 115-119
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Publication
19420382 | J:306172
First Author: Wahlstedt H
Year: 2009
Journal: Genome Res
Title: Large-scale mRNA sequencing determines global regulation of RNA editing during brain development.
Volume: 19
Issue: 6
Pages: 978-86
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Publication
35859175 | J:330287
First Author: de Reuver R
Year: 2022
Journal: Nature
Title: ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation.
Volume: 607
Issue: 7920
Pages: 784-789
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Publication
28874170 | J:317546
First Author: Heraud-Farlow JE
Year: 2017
Journal: Genome Biol
Title: Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.
Volume: 18
Issue: 1
Pages: 166
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Author
Adar S
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Author
Adar R
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Author
Adar T
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Protein Coding Gene
MGP_CAROLIEiJ_G0025215 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027444 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027372 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027417 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027159 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1889575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027863 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026605 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027133 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027380 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027259 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026339 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026659 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026158 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12954622 | J:201723
First Author: Yang JH
Year: 2003
Journal: J Biol Chem
Title: Intracellular localization of differentially regulated RNA-specific adenosine deaminase isoforms in inflammation.
Volume: 278
Issue: 46
Pages: 45833-42
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Publication
15556947 | J:96920
First Author: Yang W
Year: 2005
Journal: J Biol Chem
Title: ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells.
Volume: 280
Issue: 5
Pages: 3946-53
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Publication
19060901 | J:142338
First Author: Hartner JC
Year: 2009
Journal: Nat Immunol
Title: ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling.
Volume: 10
Issue: 1
Pages: 109-15
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Publication
26453800 | J:227773
First Author: Wang G
Year: 2015
Journal: Am J Pathol
Title: ADAR1 Prevents Liver Injury from Inflammation and Suppresses Interferon Production in Hepatocytes.
Volume: 185
Issue: 12
Pages: 3224-37
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Publication
23123729 | J:192270
First Author: Yu S
Year: 2013
Journal: Gene
Title: ADAR1 ablation decreases bone mass by impairing osteoblast function in mice.
Volume: 513
Issue: 1
Pages: 101-10
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Publication
37831098 | J:343314
First Author: Zhang B
Year: 2023
Journal: Nucleic Acids Res
Title: ADAR1 links R-loop homeostasis to ATR activation in replication stress response.
Volume: 51
Issue: 21
Pages: 11668-11687
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Publication
39120288 | J:353376
 
First Author: Cai D
Year: 2024
Journal: Cells
Title: ADAR1 Is Essential for Smooth Muscle Homeostasis and Vascular Integrity.
Volume: 13
Issue: 15
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Publication
36732946 | J:333092
First Author: Adamska JZ
Year: 2023
Journal: Cell Rep
Title: Ablation of Adar1 in myeloid cells imprints a global antiviral state in the lung and heightens early immunity against SARS-CoV-2.
Volume: 42
Issue: 1
Pages: 112038
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Publication
37801857 | J:344079
 
First Author: Cai D
Year: 2023
Journal: Redox Biol
Title: ADAR1 exacerbates ischemic brain injury via astrocyte-mediated neuron apoptosis.
Volume: 67
Pages: 102903
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Publication
33252250 | J:302380
First Author: Cui XB
Year: 2021
Journal: Am J Physiol Endocrinol Metab
Title: ADAR1 deficiency protects against high-fat diet-induced obesity and insulin resistance in mice.
Volume: 320
Issue: 1
Pages: E131-E138
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Publication
27199464 | J:250945
First Author: Fei J
Year: 2016
Journal: Circ Res
Title: ADAR1-Mediated RNA Editing, A Novel Mechanism Controlling Phenotypic Modulation of Vascular Smooth Muscle Cells.
Volume: 119
Issue: 3
Pages: 463-9
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Publication
21173229 | J:169014
First Author: Ward SV
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis.
Volume: 108
Issue: 1
Pages: 331-6
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Publication
34332594 | J:325221
First Author: Guo X
Year: 2021
Journal: J Neuroinflammation
Title: Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain.
Volume: 18
Issue: 1
Pages: 169
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Publication
10965125 | J:64308
First Author: Weier HU
Year: 2000
Journal: Cytogenet Cell Genet
Title: Assignment of the RNA-specific adenosine deaminase gene (Adar) to mouse chromosome 3F2 by in situ hybridization.
Volume: 89
Issue: 3-4
Pages: 214-5
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Publication
29694248 | J:280647
First Author: Li J
Year: 2018
Journal: FASEB J
Title: ADAR1 attenuates allogeneic graft rejection by suppressing miR-21 biogenesis in macrophages and promoting M2 polarization.
Volume: 32
Issue: 9
Pages: 5162-5173
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Publication
31801951 | J:295884
First Author: Walkley CR
Year: 2019
Journal: Cell Death Dis
Title: Cell death following the loss of ADAR1 mediated A-to-I RNA editing is not effected by the intrinsic apoptosis pathway.
Volume: 10
Issue: 12
Pages: 913
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Publication
22987615 | J:315224
First Author: Steinman RA
Year: 2013
Journal: Int J Cancer
Title: Deletion of the RNA-editing enzyme ADAR1 causes regression of established chronic myelogenous leukemia in mice.
Volume: 132
Issue: 8
Pages: 1741-50
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Publication
23598411 | J:330503
 
First Author: Qiu W
Year: 2013
Journal: Cell Death Dis
Title: ADAR1 is essential for intestinal homeostasis and stem cell maintenance.
Volume: 4
Pages: e599
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GXD Expression
GXD Expression
     
Probe: MGI:3614678
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616532
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3614678
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616532
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:6201293
Age: postnatal adult
Image: 1
Specimen Label: Oocyte
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6201293
Age: embryonic day 0.5
Image: 1
Specimen Label: Zygote
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6201293
Age: embryonic day 1.0
Image: 1
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:6201293
Age: embryonic day 2.0
Image: 1
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6201293
Age: embryonic day 2.5
Image: 1
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:6201293
Age: embryonic day 3.0
Image: 1
Specimen Label: Morula
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:6201293
Age: embryonic day 3.5
Image: 1
Specimen Label: Blastocyst
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6201293
Age: postnatal
Image: 1
Specimen Label: Testis
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:6201280
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6201293
Age: postnatal
Image: 1
Specimen Label: Brain
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:6201294
Age: postnatal adult
Image: 1
Specimen Label: Oocyte
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:6201294
Age: embryonic day 0.5
Image: 1
Specimen Label: Zygote
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6201294
Age: embryonic day 1.0
Image: 1
Specimen Label: 2-cell embryo
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:6201294
Age: embryonic day 2.0
Image: 1
Specimen Label: 4-cell embryo
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:6201294
Age: embryonic day 2.5
Image: 1
Specimen Label: 8-cell embryo
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:6201294
Age: embryonic day 3.0
Image: 1
Specimen Label: Morula
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:6201294
Age: embryonic day 3.5
Image: 1
Specimen Label: Blastocyst
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6201294
Age: postnatal
Image: 1
Specimen Label: Testis
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:6201281
Assay Type: RT-PCR
Annotation Date: 2018-10-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6201294
Age: postnatal
Image: 1
Specimen Label: Brain
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6718380
Assay Type: Western blot
Annotation Date: 2021-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:6718386
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6718380
Assay Type: Western blot
Annotation Date: 2021-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6718386
Age: embryonic day 19.0
Specimen Label: E19
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6718380
Assay Type: Western blot
Annotation Date: 2021-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6718386
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6718380
Assay Type: Western blot
Annotation Date: 2021-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6718386
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6718380
Assay Type: Western blot
Annotation Date: 2021-06-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6718386
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7539010
Assay Type: RT-PCR
Annotation Date: 2023-10-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750326
Stage: TS26
Assay Id: MGI:7539098
Age: embryonic day 18.5
Image: S1
Specimen Label: E18.5
Detected: true
Specimen Num: 1
•
•
•
•
•




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