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Search results 1 to 100 out of 122 for Add1

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Type Details Score
Gene
118 | ADD1
Type: gene
Organism: human
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Gene
740376 | ADD1
Type: gene
Organism: chimpanzee
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Gene
488796 | ADD1
Type: gene
Organism: dog, domestic
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Gene
507193 | ADD1
Type: gene
Organism: cattle
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Gene
422882 | ADD1
Type: gene
Organism: chicken
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Gene
555511 | add1
Type: gene
Organism: zebrafish
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Gene
700805 | ADD1
Type: gene
Organism: macaque, rhesus
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Gene
448173 | add1
Type: gene
Organism: frog, western clawed
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Gene
24170 | Add1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:87918 | Add1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR027766 | ADD1
Type: Family
Description: Adducin is a cytoskeletal protein that regulates the assembly of the spectrin-actin subcortical membrane network []. Adducin is present as a heterotetramer formed by two alpha subunits non covalently linked to two beta or, alternatively, to two gamma subunits depending on the cell type. Each subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region. Adducin is a substrate for protein kinase A and C (PKA, PKC) and tyrosine kinase phosphorylation and is involved in calcium cycling control, cell-to-cell contact, signal transduction, and cell motility []. This entry represents the alpha-adducin. The alpha-adducin gene has been linked to blood pressure variations in Milan hypertensive rats and humans []. Mutated alpha-adducin can cause the reduction of the Na/K pump endocytic rate. Moreover, alpha-adducin interacts with clathrin and might play a role in clathrin-dependent endocytosis [, ].
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Publication
22926980 | J:191889
First Author: Robledo RF
Year: 2012
Journal: Genesis
Title: Strain-specific hyperkyphosis and megaesophagus in Add1 null mice.
Volume: 50
Issue: 12
Pages: 882-91
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Protein
Q9QYC0
Organism: Mus musculus/domesticus
Length: 735  
Fragment?: false
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Protein
F6V4G5
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: true
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Protein
D3Z0T1
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
A0A0J9YVI4
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: true
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Protein
F8WGR0
Organism: Mus musculus/domesticus
Length: 663  
Fragment?: false
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Protein
Q8K232
Organism: Mus musculus/domesticus
Length: 735  
Fragment?: false
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Protein
F8WHZ9
Organism: Mus musculus/domesticus
Length: 662  
Fragment?: false
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Protein
Q8BJT2
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: true
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Protein
E9Q1K3
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
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Protein
F6RDR0
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
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Publication
18524856 | -
First Author: Torielli L
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: alpha-Adducin mutations increase Na/K pump activity in renal cells by affecting constitutive endocytosis: implications for tubular Na reabsorption.
Volume: 295
Issue: 2
Pages: F478-87
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Publication
7642559 | -
First Author: Hughes CA
Year: 1995
Journal: J Biol Chem
Title: Adducin: a physical model with implications for function in assembly of spectrin-actin complexes.
Volume: 270
Issue: 32
Pages: 18990-6
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Publication
11895774 | -
First Author: Gilligan DM
Year: 2002
Journal: Blood
Title: Adducin in platelets: activation-induced phosphorylation by PKC and proteolysis by calpain.
Volume: 99
Issue: 7
Pages: 2418-26
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Publication
8171025 | -
First Author: Bianchi G
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Two point mutations within the adducin genes are involved in blood pressure variation.
Volume: 91
Issue: 9
Pages: 3999-4003
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Publication
8675693 | -
First Author: Tripodi G
Year: 1996
Journal: J Clin Invest
Title: Hypertension-associated point mutations in the adducin alpha and beta subunits affect actin cytoskeleton and ion transport.
Volume: 97
Issue: 12
Pages: 2815-22
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Publication
33771994 | J:303843
First Author: Zheng K
Year: 2021
Journal: Nat Commun
Title: miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer's disease.
Volume: 12
Issue: 1
Pages: 1903
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Publication
28982183 | J:246823
First Author: Brieño-Enríquez MA
Year: 2017
Journal: PLoS One
Title: NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X.
Volume: 12
Issue: 10
Pages: e0185780
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Protein Coding Gene
MGP_CAROLIEiJ_G0027135 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029467 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029444 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_87918 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029898 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029134 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029241 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029271 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029931 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028300 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028656 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016919 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028131 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
27068466 | J:235181
First Author: Leite SC
Year: 2016
Journal: Cell Rep
Title: The Actin-Binding Protein α-Adducin Is Required for Maintaining Axon Diameter.
Volume: 15
Issue: 3
Pages: 490-498
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GXD Expression
GXD Expression
   
Probe: MGI:2181031
Assay Type: Northern blot
Annotation Date: 2002-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920925
Stage: TS25
Assay Id: MGI:2181958
Age: embryonic day 17.0
Image: 2
Specimen Label: d17 wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:2181031
Assay Type: Northern blot
Annotation Date: 2002-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920925
Stage: TS25
Assay Id: MGI:2181958
Age: embryonic day 17.0
Image: 2
Specimen Label: d17 -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:2181031
Assay Type: Northern blot
Annotation Date: 2002-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:2181958
Age: embryonic day 18.0
Image: 2
Specimen Label: d18 wt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:2181031
Assay Type: Northern blot
Annotation Date: 2002-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920926
Stage: TS26
Assay Id: MGI:2181958
Age: embryonic day 18.0
Image: 2
Specimen Label: d18 -/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2181031
Assay Type: Northern blot
Annotation Date: 2002-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:2181958
Age: postnatal newborn
Image: 2
Specimen Label: NB wt
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:2181031
Assay Type: Northern blot
Annotation Date: 2002-07-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1920927
Stage: TS27
Assay Id: MGI:2181958
Age: postnatal newborn
Image: 2
Specimen Label: NB -/-
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5640686
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647224
Stage: TS24
Assay Id: MGI:5640791
Age: embryonic day 16.5
Image: S5
Specimen Label: bv/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5640686
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3647224
Stage: TS24
Assay Id: MGI:5640791
Age: embryonic day 16.5
Image: S5
Specimen Label: bv/bv
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5640686
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5640842
Age: postnatal day 15
Image: S5
Specimen Label: ce
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5640686
Assay Type: RT-PCR
Annotation Date: 2015-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5640842
Age: postnatal day 15
Image: S5
Specimen Label: sp
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5640686
Assay Type: RT-PCR
Annotation Date: 2015-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5641067
Age: postnatal day 15
Image: S7
Specimen Label: bv/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5640686
Assay Type: RT-PCR
Annotation Date: 2015-06-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5641067
Age: postnatal day 15
Image: S7
Specimen Label: bv/bv
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4416681
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530852
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
10845937 | J:63047
First Author: Muro AF
Year: 2000
Journal: Blood
Title: Mild spherocytic hereditary elliptocytosis and altered levels of alpha- and gamma-adducins in beta-adducin-deficient mice.
Volume: 95
Issue: 12
Pages: 3978-85
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Publication
10485892 | J:71029
First Author: Gilligan DM
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of the beta adducin gene (Add2) causes red blood cell spherocytosis in mice.
Volume: 96
Issue: 19
Pages: 10717-22
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Publication
25978380 | J:235423
First Author: Kugelmann D
Year: 2015
Journal: PLoS One
Title: Adducin is involved in endothelial barrier stabilization.
Volume: 10
Issue: 5
Pages: e0126213
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Publication
1864459 | J:33510
First Author: Pinto-Correia C
Year: 1991
Journal: Dev Biol
Title: Immunofluorescence localization of an adducin-like protein in the chromosomes of mouse oocytes.
Volume: 146
Issue: 2
Pages: 301-11
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Publication
19900187 | J:169203
First Author: Porro F
Year: 2010
Journal: Genes Brain Behav
Title: beta-adducin (Add2) KO mice show synaptic plasticity, motor coordination and behavioral deficits accompanied by changes in the expression and phosphorylation levels of the alpha- and gamma-adducin subunits.
Volume: 9
Issue: 1
Pages: 84-96
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Publication
22147703 | J:185103
First Author: Kodippili GC
Year: 2012
Journal: J Biol Chem
Title: Analysis of the mobilities of band 3 populations associated with ankyrin protein and junctional complexes in intact murine erythrocytes.
Volume: 287
Issue: 6
Pages: 4129-38
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Publication
11152656 | J:67077
First Author: Näf D
Year: 2001
Journal: Hum Mol Genet
Title: Mouse models for the Wolf-Hirschhorn deletion syndrome.
Volume: 10
Issue: 2
Pages: 91-8
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Publication
34269176 | J:317350
   
First Author: O'Neil SD
Year: 2021
Journal: Elife
Title: Action potential-coupled Rho GTPase signaling drives presynaptic plasticity.
Volume: 10
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Publication
17074803 | J:117710
First Author: Lee YS
Year: 2007
Journal: Mol Cell Biol
Title: Chromatin remodeling complex interacts with ADD1/SREBP1c to mediate insulin-dependent regulation of gene expression.
Volume: 27
Issue: 2
Pages: 438-52
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Publication
10602987 | J:59226
First Author: Suriyapperuma SP
Year: 2000
Journal: Mamm Genome
Title: The mouse adducin gene family: alternative splicing and chromosomal localization.
Volume: 11
Issue: 1
Pages: 16-23
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Publication
7959767 | J:19414
First Author: Nasir J
Year: 1994
Journal: Genomics
Title: The murine homologues of the Huntington disease gene (Hdh) and the alpha-adducin gene (Add1) map to mouse chromosome 5 within a region of conserved synteny with human chromosome 4p16.3.
Volume: 22
Issue: 1
Pages: 198-201
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Publication
19501643 | J:155777
First Author: Pawlowski TL
Year: 2009
Journal: Genomics
Title: Candidate Agtr2 influenced genes and pathways identified by expression profiling in the developing brain of Agtr2(-/y) mice.
Volume: 94
Issue: 3
Pages: 188-95
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Publication
17244351 | J:123131
First Author: Yu X
Year: 2007
Journal: Arthritis Res Ther
Title: Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis.
Volume: 9
Issue: 1
Pages: R3
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Publication
18723693 | J:138919
First Author: Robledo RF
Year: 2008
Journal: Blood
Title: Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.
Volume: 112
Issue: 10
Pages: 4298-307
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Publication
7919654 | J:19185
First Author: Grosson CL
Year: 1994
Journal: Mamm Genome
Title: Synteny conservation of the Huntington's disease gene and surrounding loci on mouse Chromosome 5.
Volume: 5
Issue: 7
Pages: 424-8
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Publication
11110696 | J:61187
First Author: Gwynn B
Year: 2000
Journal: Blood
Title: Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.
Volume: 96
Issue: 13
Pages: 4227-35
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Publication
20696915 | J:163685
First Author: Siatecka M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.
Volume: 107
Issue: 34
Pages: 15151-6
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Publication
11940593 | J:76945
First Author: Carmona MC
Year: 2002
Journal: J Biol Chem
Title: Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha.
Volume: 277
Issue: 24
Pages: 21489-98
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Publication
24803591 | J:213512
First Author: Werber M
Year: 2014
Journal: Development
Title: The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo.
Volume: 141
Issue: 11
Pages: 2325-30
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Publication
27565344 | J:236302
First Author: Zhang X
Year: 2016
Journal: Cell
Title: Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.
Volume: 166
Issue: 5
Pages: 1147-1162.e15
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Publication
23055939 | J:193641
First Author: Nakano Y
Year: 2012
Journal: PLoS Genet
Title: A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse.
Volume: 8
Issue: 10
Pages: e1002966
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Publication
30995482 | J:281311
First Author: Nakano Y
Year: 2019
Journal: Cell Rep
Title: Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.
Volume: 27
Issue: 3
Pages: 860-871.e8
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:345476
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2023
Title: TreeGrafter-generated GO annotations
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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