Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
rabbit, European |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
326
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Province HS |
Year: |
2020 |
Journal: |
PLoS One |
Title: |
Activation of neuronal adenosine A1 receptors causes hypothermia through central and peripheral mechanisms. |
Volume: |
15 |
Issue: |
12 |
Pages: |
e0243986 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yip L |
Year: |
2013 |
Journal: |
Diabetes |
Title: |
Diminished adenosine A1 receptor expression in pancreatic α-cells may contribute to the pathology of type 1 diabetes. |
Volume: |
62 |
Issue: |
12 |
Pages: |
4208-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Granade ME |
Year: |
2022 |
Journal: |
Mol Metab |
Title: |
Feeding desensitizes A1 adenosine receptors in adipose through FOXO1-mediated transcriptional regulation. |
Volume: |
63 |
|
Pages: |
101543 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Rivkees SA |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Characterization of the murine A1 adenosine receptor promoter, potent regulation by GATA-4 and Nkx2.5. |
Volume: |
274 |
Issue: |
20 |
Pages: |
14204-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johansson B |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor. |
Volume: |
98 |
Issue: |
16 |
Pages: |
9407-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brown R |
Year: |
2001 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Abolished tubuloglomerular feedback and increased plasma renin in adenosine A1 receptor-deficient mice. |
Volume: |
281 |
Issue: |
5 |
Pages: |
R1362-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johansson SM |
Year: |
2007 |
Journal: |
Biochem Pharmacol |
Title: |
A1 receptor deficiency causes increased insulin and glucagon secretion in mice. |
Volume: |
74 |
Issue: |
11 |
Pages: |
1628-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang GK |
Year: |
2012 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Improved blood glucose disposal and altered insulin secretion patterns in adenosine A(1) receptor knockout mice. |
Volume: |
303 |
Issue: |
2 |
Pages: |
E180-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kara FM |
Year: |
2010 |
Journal: |
FASEB J |
Title: |
Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function. |
Volume: |
24 |
Issue: |
7 |
Pages: |
2325-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao X |
Year: |
2011 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Adenosine A₁-receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment. |
Volume: |
301 |
Issue: |
6 |
Pages: |
R1669-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johansson SM |
Year: |
2008 |
Journal: |
Eur J Pharmacol |
Title: |
Adenosine A1 receptors regulate lipolysis and lipogenesis in mouse adipose tissue-interactions with insulin. |
Volume: |
597 |
Issue: |
1-3 |
Pages: |
92-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wendler CC |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A1 adenosine receptors play an essential role in protecting the embryo against hypoxia. |
Volume: |
104 |
Issue: |
23 |
Pages: |
9697-702 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu WP |
Year: |
2005 |
Journal: |
Pain |
Title: |
Increased nociceptive response in mice lacking the adenosine A1 receptor. |
Volume: |
113 |
Issue: |
3 |
Pages: |
395-404 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brown RD |
Year: |
2006 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Influence of the adenosine A1 receptor on blood pressure regulation and renin release. |
Volume: |
290 |
Issue: |
5 |
Pages: |
R1324-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Olsson T |
Year: |
2004 |
Journal: |
Eur J Neurosci |
Title: |
Deletion of the adenosine A1 receptor gene does not alter neuronal damage following ischaemia in vivo or in vitro. |
Volume: |
20 |
Issue: |
5 |
Pages: |
1197-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stenberg D |
Year: |
2003 |
Journal: |
J Sleep Res |
Title: |
Sleep and its homeostatic regulation in mice lacking the adenosine A1 receptor. |
Volume: |
12 |
Issue: |
4 |
Pages: |
283-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lankford AR |
Year: |
2006 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Effect of modulating cardiac A1 adenosine receptor expression on protection with ischemic preconditioning. |
Volume: |
290 |
Issue: |
4 |
Pages: |
H1469-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ponnoth DS |
Year: |
2010 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Involvement of A1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma. |
Volume: |
299 |
Issue: |
1 |
Pages: |
H81-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fedele DE |
Year: |
2006 |
Journal: |
Exp Neurol |
Title: |
Adenosine A1 receptors are crucial in keeping an epileptic focus localized. |
Volume: |
200 |
Issue: |
1 |
Pages: |
184-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang T |
Year: |
2015 |
Journal: |
Diabetologia |
Title: |
Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses. |
Volume: |
58 |
Issue: |
7 |
Pages: |
1610-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Halldner L |
Year: |
2004 |
Journal: |
Neuropharmacology |
Title: |
The adenosine A1 receptor contributes to the stimulatory, but not the inhibitory effect of caffeine on locomotion: a study in mice lacking adenosine A1 and/or A2A receptors. |
Volume: |
46 |
Issue: |
7 |
Pages: |
1008-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kukley M |
Year: |
2005 |
Journal: |
J Neurosci |
Title: |
The role of extracellular adenosine in regulating mossy fiber synaptic plasticity. |
Volume: |
25 |
Issue: |
11 |
Pages: |
2832-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Buscariollo DL |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Embryonic caffeine exposure acts via A1 adenosine receptors to alter adult cardiac function and DNA methylation in mice. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e87547 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chasse R |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Altered Heterosynaptic Plasticity Impairs Visual Discrimination Learning in Adenosine A1 Receptor Knock-Out Mice. |
Volume: |
41 |
Issue: |
21 |
Pages: |
4631-4640 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sawynok J |
Year: |
2010 |
Journal: |
Neurosci Lett |
Title: |
Caffeine reverses antinociception by oxcarbazepine by inhibition of adenosine A1 receptors: insights using knockout mice. |
Volume: |
473 |
Issue: |
3 |
Pages: |
178-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sawynok J |
Year: |
2008 |
Journal: |
Neurosci Lett |
Title: |
Caffeine reverses antinociception by amitriptyline in wild type mice but not in those lacking adenosine A1 receptors. |
Volume: |
440 |
Issue: |
2 |
Pages: |
181-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giménez-Llort L |
Year: |
2002 |
Journal: |
Eur J Neurosci |
Title: |
Mice lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate. |
Volume: |
16 |
Issue: |
3 |
Pages: |
547-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Minelli A |
Year: |
2004 |
Journal: |
J Androl |
Title: |
Involvement of A1 adenosine receptors in the acquisition of fertilizing capacity. |
Volume: |
25 |
Issue: |
2 |
Pages: |
286-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang S |
Year: |
2015 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Adenosine A1 Receptors Selectively Modulate Oxygen-Induced Retinopathy at the Hyperoxic and Hypoxic Phases by Distinct Cellular Mechanisms. |
Volume: |
56 |
Issue: |
13 |
Pages: |
8108-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun D |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mediation of tubuloglomerular feedback by adenosine: evidence from mice lacking adenosine 1 receptors. |
Volume: |
98 |
Issue: |
17 |
Pages: |
9983-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bekar L |
Year: |
2008 |
Journal: |
Nat Med |
Title: |
Adenosine is crucial for deep brain stimulation-mediated attenuation of tremor. |
Volume: |
14 |
Issue: |
1 |
Pages: |
75-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lang UE |
Year: |
2003 |
Journal: |
Behav Brain Res |
Title: |
Emotional instability but intact spatial cognition in adenosine receptor 1 knock out mice. |
Volume: |
145 |
Issue: |
1-2 |
Pages: |
179-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rieg T |
Year: |
2007 |
Journal: |
Eur J Pharmacol |
Title: |
Adenosine A1 receptors determine effects of caffeine on total fluid intake but not caffeine appetite. |
Volume: |
555 |
Issue: |
2-3 |
Pages: |
174-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ansari HR |
Year: |
2009 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells. |
Volume: |
297 |
Issue: |
3 |
Pages: |
H1032-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bell TD |
Year: |
2010 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Glomerular tubular balance is suppressed in adenosine type 1 receptor-deficient mice. |
Volume: |
299 |
Issue: |
5 |
Pages: |
F1158-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Street JM |
Year: |
2018 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
The role of adenosine 1a receptor signaling on GFR early after the induction of sepsis. |
Volume: |
314 |
Issue: |
5 |
Pages: |
F788-F797 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aeffner F |
Year: |
2014 |
Journal: |
J Virol |
Title: |
Activation of A1-adenosine receptors promotes leukocyte recruitment to the lung and attenuates acute lung injury in mice infected with influenza A/WSN/33 (H1N1) virus. |
Volume: |
88 |
Issue: |
17 |
Pages: |
10214-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hashimoto S |
Year: |
2006 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Reduced autoregulatory effectiveness in adenosine 1 receptor-deficient mice. |
Volume: |
290 |
Issue: |
4 |
Pages: |
F888-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gallos G |
Year: |
2005 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
A1 adenosine receptor knockout mice exhibit increased mortality, renal dysfunction, and hepatic injury in murine septic peritonitis. |
Volume: |
289 |
Issue: |
2 |
Pages: |
F369-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SM |
Year: |
2006 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Adenosine as a mediator of macula densa-dependent inhibition of renin secretion. |
Volume: |
290 |
Issue: |
5 |
Pages: |
F1016-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee HT |
Year: |
2004 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
A1 adenosine receptor knockout mice exhibit increased renal injury following ischemia and reperfusion. |
Volume: |
286 |
Issue: |
2 |
Pages: |
F298-306 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ngamsri KC |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Adenosine receptor A1 regulates polymorphonuclear cell trafficking and microvascular permeability in lipopolysaccharide-induced lung injury. |
Volume: |
185 |
Issue: |
7 |
Pages: |
4374-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Faulhaber-Walter R |
Year: |
2011 |
Journal: |
Diabetes |
Title: |
Impaired glucose tolerance in the absence of adenosine A1 receptor signaling. |
Volume: |
60 |
Issue: |
10 |
Pages: |
2578-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vallon V |
Year: |
2004 |
Journal: |
Pflugers Arch |
Title: |
Functional consequences at the single-nephron level of the lack of adenosine A1 receptors and tubuloglomerular feedback in mice. |
Volume: |
448 |
Issue: |
2 |
Pages: |
214-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tawfik HE |
Year: |
2006 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Role of A1 adenosine receptor in the regulation of coronary flow. |
Volume: |
291 |
Issue: |
1 |
Pages: |
H467-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee HT |
Year: |
2006 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
A1 adenosine receptor knockout mice are protected against acute radiocontrast nephropathy in vivo. |
Volume: |
290 |
Issue: |
6 |
Pages: |
F1367-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim M |
Year: |
2009 |
Journal: |
Kidney Int |
Title: |
Kidney-specific reconstitution of the A1 adenosine receptor in A1 adenosine receptor knockout mice reduces renal ischemia-reperfusion injury. |
Volume: |
75 |
Issue: |
8 |
Pages: |
809-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen PB |
Year: |
2003 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Attenuated renovascular constrictor responses to angiotensin II in adenosine 1 receptor knockout mice. |
Volume: |
285 |
Issue: |
1 |
Pages: |
R44-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reichelt ME |
Year: |
2005 |
Journal: |
Circ Res |
Title: |
Genetic deletion of the A1 adenosine receptor limits myocardial ischemic tolerance. |
Volume: |
96 |
Issue: |
3 |
Pages: |
363-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schweda F |
Year: |
2003 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Preserved macula densa-dependent renin secretion in A1 adenosine receptor knockout mice. |
Volume: |
284 |
Issue: |
4 |
Pages: |
F770-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang P |
Year: |
2013 |
Journal: |
Toxicol Sci |
Title: |
Loss of A(1) adenosine receptor attenuates alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice. |
Volume: |
131 |
Issue: |
1 |
Pages: |
128-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
McIntosh VJ |
Year: |
2011 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Sex differences and the effects of ovariectomy on the β-adrenergic contractile response. |
Volume: |
301 |
Issue: |
3 |
Pages: |
H1127-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rieg T |
Year: |
2008 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Vasopressin regulation of inner medullary collecting ducts and compensatory changes in mice lacking adenosine A1 receptors. |
Volume: |
294 |
Issue: |
3 |
Pages: |
F638-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teng B |
Year: |
2006 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Isolation and characterization of coronary endothelial and smooth muscle cells from A1 adenosine receptor-knockout mice. |
Volume: |
290 |
Issue: |
4 |
Pages: |
H1713-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsutsui S |
Year: |
2004 |
Journal: |
J Neurosci |
Title: |
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. |
Volume: |
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