Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
rabbit, European |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
hamster, golden |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates the biological and toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), dioxin-like compounds (DLC), as well as some drugs and endogenous tryptophan metabolites []. Without ligands, AHR is part of the Hsp90/XAP2 (heat shock protein 90/hepatitis B virus X-associated protein) multi-chaperone protein complex. Upon ligand binding, the receptor dissociates from the chaperone complex and translocates into the nucleus where it heterodimerises with ARNT (AHR nuclear translocator). The respective heterodimeric complex then modulates the cell's transcriptional activity by binding to specific xenobiotic response elements (XREs) in the promoters of AHR target genes [, ]. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Seok SH |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. |
Volume: |
114 |
Issue: |
21 |
Pages: |
5431-5436 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
48
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
848
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
883
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
848
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
429
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
429
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
429
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
429
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
429
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Oshida K |
Year: |
2015 |
Journal: |
Toxicology |
Title: |
Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR). |
Volume: |
336 |
|
Pages: |
99-112 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tarnow P |
Year: |
2016 |
Journal: |
Arch Toxicol |
Title: |
G protein-coupled receptor 30 ligand G-1 increases aryl hydrocarbon receptor signalling by inhibition of tubulin assembly and cell cycle arrest in human MCF-7 cells. |
Volume: |
90 |
Issue: |
8 |
Pages: |
1939-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lahvis GP |
Year: |
1998 |
Journal: |
Biochem Pharmacol |
Title: |
Ahr null alleles: distinctive or different? |
Volume: |
56 |
Issue: |
7 |
Pages: |
781-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moura-Alves P |
Year: |
2014 |
Journal: |
Nature |
Title: |
AhR sensing of bacterial pigments regulates antibacterial defence. |
Volume: |
512 |
Issue: |
7515 |
Pages: |
387-92 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
114
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
848
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
420
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
420
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
420
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
420
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
805
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Falahatpisheh MH |
Year: |
2011 |
Journal: |
Mol Med |
Title: |
AHR regulates WT1 genetic programming during murine nephrogenesis. |
Volume: |
17 |
Issue: |
11-12 |
Pages: |
1275-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schiering C |
Year: |
2017 |
Journal: |
Nature |
Title: |
Feedback control of AHR signalling regulates intestinal immunity. |
Volume: |
542 |
Issue: |
7640 |
Pages: |
242-245 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu D |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
AhR deficiency impairs expression of LPS-induced inflammatory genes in mice. |
Volume: |
410 |
Issue: |
2 |
Pages: |
358-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thomae TL |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
A maternal Ahr null genotype sensitizes embryos to chemical teratogenesis. |
Volume: |
279 |
Issue: |
29 |
Pages: |
30189-94 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167131 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
|
Stage: |
TS19 |
Assay Id: |
MGI:6189754 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Ahr |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167131 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6189754 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Ahr |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167131 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
|
Stage: |
TS24 |
Assay Id: |
MGI:6189754 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Ahr |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167131 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6189754 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Ahr |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167131 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6189754 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Ahr |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167131 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189754 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Ahr |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167131 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189754 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Ahr |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim YC |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. |
Volume: |
9 |
Issue: |
1 |
Pages: |
540 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsieh TH |
Year: |
2022 |
Journal: |
Biomed Pharmacother |
Title: |
DEHP mediates drug resistance by directly targeting AhR in human breast cancer. |
Volume: |
145 |
|
Pages: |
112400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Granados JC |
Year: |
2022 |
Journal: |
Sci Rep |
Title: |
AHR is a master regulator of diverse pathways in endogenous metabolism. |
Volume: |
12 |
Issue: |
1 |
Pages: |
16625 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gutierrez MA |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
A novel AhR ligand, 2AI, protects the retina from environmental stress. |
Volume: |
6 |
|
Pages: |
29025 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bennett JA |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
Conditional deletion of Ahr alters gene expression profiles in hematopoietic stem cells. |
Volume: |
13 |
Issue: |
11 |
Pages: |
e0206407 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cochez PM |
Year: |
2016 |
Journal: |
Eur J Immunol |
Title: |
AhR modulates the IL-22-producing cell proliferation/recruitment in imiquimod-induced psoriasis mouse model. |
Volume: |
46 |
Issue: |
6 |
Pages: |
1449-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
de la Parra J |
Year: |
2018 |
Journal: |
eNeuro |
Title: |
AhR Deletion Promotes Aberrant Morphogenesis and Synaptic Activity of Adult-Generated Granule Neurons and Impairs Hippocampus-Dependent Memory. |
Volume: |
5 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Takenaka MC |
Year: |
2019 |
Journal: |
Nat Neurosci |
Title: |
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39. |
Volume: |
22 |
Issue: |
5 |
Pages: |
729-740 |
|
•
•
•
•
•
|
Publication |
First Author: |
Noda S |
Year: |
2003 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse. |
Volume: |
303 |
Issue: |
1 |
Pages: |
105-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang R |
Year: |
2023 |
Journal: |
Immunity |
Title: |
Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis. |
Volume: |
56 |
Issue: |
12 |
Pages: |
2736-2754.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Falahatpisheh MH |
Year: |
2003 |
Journal: |
Oncogene |
Title: |
Ligand-activated Ahr signaling leads to disruption of nephrogenesis and altered Wilms' tumor suppressor mRNA splicing. |
Volume: |
22 |
Issue: |
14 |
Pages: |
2160-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson RH |
Year: |
2021 |
Journal: |
Toxicol Sci |
Title: |
Generation of an Allelic Series at the Ahr Locus Using an Edited Recombinant Approach. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bhattacharya S |
Year: |
2014 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
The genome-wide transcriptional response to neonatal hyperoxia identifies Ahr as a key regulator. |
Volume: |
307 |
Issue: |
7 |
Pages: |
L516-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schmidt JV |
Year: |
1993 |
Journal: |
J Biol Chem |
Title: |
Molecular characterization of the murine Ahr gene. Organization, promoter analysis, and chromosomal assignment. |
Volume: |
268 |
Issue: |
29 |
Pages: |
22203-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith SH |
Year: |
2017 |
Journal: |
J Invest Dermatol |
Title: |
Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans. |
Volume: |
137 |
Issue: |
10 |
Pages: |
2110-2119 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Araújo EF |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Pulmonary paracoccidioidomycosis in AhR deficient hosts is severe and associated with defective Treg and Th22 responses. |
Volume: |
10 |
Issue: |
1 |
Pages: |
11312 |
|
•
•
•
•
•
|
Publication |
First Author: |
Izawa T |
Year: |
2016 |
Journal: |
J Immunol |
Title: |
The Nuclear Receptor AhR Controls Bone Homeostasis by Regulating Osteoclast Differentiation via the RANK/c-Fos Signaling Axis. |
Volume: |
197 |
Issue: |
12 |
Pages: |
4639-4650 |
|
•
•
•
•
•
|
Publication |
First Author: |
van den Bogaard EH |
Year: |
2015 |
Journal: |
J Invest Dermatol |
Title: |
Genetic and pharmacological analysis identifies a physiological role for the AHR in epidermal differentiation. |
Volume: |
135 |
Issue: |
5 |
Pages: |
1320-1328 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang F |
Year: |
2020 |
Journal: |
Microb Cell Fact |
Title: |
Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles. |
Volume: |
19 |
Issue: |
1 |
Pages: |
219 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gérard D |
Year: |
2018 |
Journal: |
Nucleic Acids Res |
Title: |
Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pollet M |
Year: |
2018 |
Journal: |
Cell Death Differ |
Title: |
The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis. |
Volume: |
25 |
Issue: |
10 |
Pages: |
1823-1836 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bui LC |
Year: |
2016 |
Journal: |
Toxicol Sci |
Title: |
Regulation of Aquaporin 3 Expression by the AhR Pathway Is Critical to Cell Migration. |
Volume: |
149 |
Issue: |
1 |
Pages: |
158-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kahalehili HM |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice. |
Volume: |
11 |
|
Pages: |
606441 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mascanfroni ID |
Year: |
2015 |
Journal: |
Nat Med |
Title: |
Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α. |
Volume: |
21 |
Issue: |
6 |
Pages: |
638-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walisser JA |
Year: |
2004 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Gestational exposure of Ahr and Arnt hypomorphs to dioxin rescues vascular development. |
Volume: |
101 |
Issue: |
47 |
Pages: |
16677-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang W |
Year: |
2004 |
Journal: |
Toxicol Sci |
Title: |
A Cyp1a2-luciferase transgenic CD-1 mouse model: responses to aryl hydrocarbons similar to the humanized AhR mice. |
Volume: |
82 |
Issue: |
1 |
Pages: |
297-307 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sarić N |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
The AHR pathway represses TGFβ-SMAD3 signalling and has a potent tumour suppressive role in SHH medulloblastoma. |
Volume: |
10 |
Issue: |
1 |
Pages: |
148 |
|
•
•
•
•
•
|
Publication |
First Author: |
Merches K |
Year: |
2020 |
Journal: |
Int J Mol Sci |
Title: |
AHR Signaling Dampens Inflammatory Signature in Neonatal Skin γδ T Cells. |
Volume: |
21 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kubli SP |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer. |
Volume: |
116 |
Issue: |
9 |
Pages: |
3604-3613 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hidaka T |
Year: |
2017 |
Journal: |
Nat Immunol |
Title: |
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin. |
Volume: |
18 |
Issue: |
1 |
Pages: |
64-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dant TA |
Year: |
2017 |
Journal: |
Blood |
Title: |
T-cell expression of AhR inhibits the maintenance of pTreg cells in the gastrointestinal tract in acute GVHD. |
Volume: |
130 |
Issue: |
3 |
Pages: |
348-359 |
|
•
•
•
•
•
|
Publication |
First Author: |
Metidji A |
Year: |
2018 |
Journal: |
Immunity |
Title: |
The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity. |
Volume: |
49 |
Issue: |
2 |
Pages: |
353-362.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Franchini AM |
Year: |
2019 |
Journal: |
Immunohorizons |
Title: |
Genome-Wide Transcriptional Analysis Reveals Novel AhR Targets That Regulate Dendritic Cell Function during Influenza A Virus Infection. |
Volume: |
3 |
Issue: |
6 |
Pages: |
219-235 |
|
•
•
•
•
•
|
Publication |
First Author: |
Makhloufi C |
Year: |
2020 |
Journal: |
Int J Mol Sci |
Title: |
Female AhR Knockout Mice Develop a Minor Renal Insufficiency in an Adenine-Diet Model of Chronic Kidney Disease. |
Volume: |
21 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wheeler JL |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Novel cellular targets of AhR underlie alterations in neutrophilic inflammation and inducible nitric oxide synthase expression during influenza virus infection. |
Volume: |
190 |
Issue: |
2 |
Pages: |
659-68 |
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Publication |
First Author: |
Shinde R |
Year: |
2018 |
Journal: |
Nat Immunol |
Title: |
Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans. |
Volume: |
19 |
Issue: |
6 |
Pages: |
571-582 |
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Publication |
First Author: |
Lee JS |
Year: |
2011 |
Journal: |
Nat Immunol |
Title: |
AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. |
Volume: |
13 |
Issue: |
2 |
Pages: |
144-51 |
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Publication |
First Author: |
Boule LA |
Year: |
2015 |
Journal: |
Toxicol Sci |
Title: |
Developmental Activation of the AHR Increases Effector CD4+ T Cells and Exacerbates Symptoms in Autoimmune Disease-Prone Gnaq+/- Mice. |
Volume: |
148 |
Issue: |
2 |
Pages: |
555-66 |
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Publication |
First Author: |
Kim SY |
Year: |
2014 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Deletion of aryl hydrocarbon receptor AHR in mice leads to subretinal accumulation of microglia and RPE atrophy. |
Volume: |
55 |
Issue: |
9 |
Pages: |
6031-40 |
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Publication |
First Author: |
Kumar S |
Year: |
2017 |
Journal: |
J Leukoc Biol |
Title: |
Hepatic stellate cells increase the immunosuppressive function of natural Foxp3+ regulatory T cells via IDO-induced AhR activation. |
Volume: |
101 |
Issue: |
2 |
Pages: |
429-438 |
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Publication |
First Author: |
Zago M |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Low levels of the AhR in chronic obstructive pulmonary disease (COPD)-derived lung cells increases COX-2 protein by altering mRNA stability. |
Volume: |
12 |
Issue: |
7 |
Pages: |
e0180881 |
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Publication |
First Author: |
Smith AG |
Year: |
1998 |
Journal: |
Mol Pharmacol |
Title: |
Interaction between iron metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: a hepatic oxidative mechanism. |
Volume: |
53 |
Issue: |
1 |
Pages: |
52-61 |
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Publication |
First Author: |
Hong CH |
Year: |
2020 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Selective AhR knockout in langerin-expressing cells abates Langerhans cells and polarizes Th2/Tr1 in epicutaneous protein sensitization. |
Volume: |
117 |
Issue: |
23 |
Pages: |
12980-12990 |
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Publication |
First Author: |
Karchner SI |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Regulatory interactions among three members of the vertebrate aryl hydrocarbon receptor family: AHR repressor, AHR1, and AHR2. |
Volume: |
277 |
Issue: |
9 |
Pages: |
6949-59 |
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Publication |
First Author: |
Schmidt JV |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. |
Volume: |
93 |
Issue: |
13 |
Pages: |
6731-6 |
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Publication |
First Author: |
Butler RA |
Year: |
2001 |
Journal: |
Gene |
Title: |
An aryl hydrocarbon receptor (AHR) homologue from the soft-shell clam, Mya arenaria: evidence that invertebrate AHR homologues lack 2,3,7,8-tetrachlorodibenzo-p-dioxin and beta-naphthoflavone binding. |
Volume: |
278 |
Issue: |
1-2 |
Pages: |
223-34 |
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Publication |
First Author: |
Curran CP |
Year: |
2011 |
Journal: |
Toxicol Sci |
Title: |
In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes. |
Volume: |
119 |
Issue: |
1 |
Pages: |
189-208 |
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Publication |
First Author: |
Neamah WH |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes. |
Volume: |
203 |
Issue: |
7 |
Pages: |
1830-1844 |
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Publication |
First Author: |
Sahlberg C |
Year: |
2002 |
Journal: |
Int J Dev Biol |
Title: |
Expression of the mediators of dioxin toxicity, aryl hydrocarbon receptor (AHR) and the AHR nuclear translocator (ARNT), is developmentally regulated in mouse teeth. |
Volume: |
46 |
Issue: |
3 |
Pages: |
295-300 |
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Publication |
First Author: |
Moyer BJ |
Year: |
2016 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. |
Volume: |
300 |
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Pages: |
13-24 |
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Publication |
First Author: |
Curran CP |
Year: |
2011 |
Journal: |
Environ Health Perspect |
Title: |
In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes. |
Volume: |
119 |
Issue: |
9 |
Pages: |
1286-93 |
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Publication |
First Author: |
Larsen MC |
Year: |
2023 |
Journal: |
Int J Mol Sci |
Title: |
AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors. |
Volume: |
24 |
Issue: |
23 |
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Publication |
First Author: |
Biagioli M |
Year: |
2021 |
Journal: |
bioRxiv |
Title: |
Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression in rodent models of inflammation and attenuates ACE2 - SARS-CoV2 interaction in vitro. |
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Publication |
First Author: |
Powell DN |
Year: |
2020 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging. |
Volume: |
117 |
Issue: |
35 |
Pages: |
21519-21526 |
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Publication |
First Author: |
Kerkvliet NI |
Year: |
2002 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is necessary for full suppression of a cytotoxic T lymphocyte response by TCDD. |
Volume: |
185 |
Issue: |
2 |
Pages: |
146-52 |
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Publication |
First Author: |
Weighardt H |
Year: |
2024 |
Journal: |
J Leukoc Biol |
Title: |
The AHR repressor limits expression of antimicrobial genes but not AHR-dependent genes in intestinal eosinophils. |
Volume: |
116 |
Issue: |
2 |
Pages: |
369-378 |
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