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Search results 1 to 100 out of 229 for Aim2

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Fernandes-Alnemri T
Year: 2010
Journal: Nat Immunol
Title: The AIM2 inflammasome is critical for innate immunity to Francisella tularensis.
Volume: 11
Issue: 5
Pages: 385-93
Publication
First Author: Fernandes-Alnemri T
Year: 2009
Journal: Nature
Title: AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.
Volume: 458
Issue: 7237
Pages: 509-13
Publication
First Author: Belhocine K
Year: 2012
Journal: Cell Microbiol
Title: Francisella infection triggers activation of the AIM2 inflammasome in murine dendritic cells.
Volume: 14
Issue: 1
Pages: 71-80
Publication
First Author: Hornung V
Year: 2009
Journal: Nature
Title: AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Volume: 458
Issue: 7237
Pages: 514-8
Publication
First Author: Rathinam VA
Year: 2010
Journal: Nat Immunol
Title: The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses.
Volume: 11
Issue: 5
Pages: 395-402
Publication
First Author: Saiga H
Year: 2012
Journal: Int Immunol
Title: Critical role of AIM2 in Mycobacterium tuberculosis infection.
Volume: 24
Issue: 10
Pages: 637-44
Publication
First Author: Chou WC
Year: 2021
Journal: Nature
Title: AIM2 in regulatory T cells restrains autoimmune diseases.
Volume: 591
Issue: 7849
Pages: 300-305
Publication
First Author: Lammert CR
Year: 2020
Journal: Nature
Title: AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment.
Volume: 580
Issue: 7805
Pages: 647-652
Publication  
First Author: Chen J
Year: 2019
Journal: Brain Res Bull
Title: AIM2 deletion promotes neuroplasticity and spatial memory of mice.
Volume: 152
Pages: 85-94
Publication
First Author: Pan J
Year: 2018
Journal: Biochem Biophys Res Commun
Title: AIM2 regulates vascular smooth muscle cell migration in atherosclerosis.
Volume: 497
Issue: 1
Pages: 401-409
Publication
First Author: Sauer JD
Year: 2010
Journal: Cell Host Microbe
Title: Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol.
Volume: 7
Issue: 5
Pages: 412-9
Publication
First Author: Liu T
Year: 2016
Journal: Cell Rep
Title: TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective Autophagy.
Volume: 16
Issue: 7
Pages: 1988-2002
Publication
First Author: Jones JW
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.
Volume: 107
Issue: 21
Pages: 9771-6
Publication  
First Author: Xie M
Year: 2016
Journal: Nat Commun
Title: PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.
Volume: 7
Pages: 13280
Publication
First Author: Dang EV
Year: 2017
Journal: Cell
Title: Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation.
Volume: 171
Issue: 5
Pages: 1057-1071.e11
Publication
First Author: Pan J
Year: 2018
Journal: Biochem Biophys Res Commun
Title: AIM2 accelerates the atherosclerotic plaque progressions in ApoE-/- mice.
Volume: 498
Issue: 3
Pages: 487-494
Publication
First Author: Hupa KJ
Year: 2019
Journal: Sci Rep
Title: AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice.
Volume: 9
Issue: 1
Pages: 10602
Publication
First Author: Martínez-Cardona C
Year: 2018
Journal: Int J Cancer
Title: AIM2 deficiency reduces the development of hepatocellular carcinoma in mice.
Volume: 143
Issue: 11
Pages: 2997-3007
Publication
First Author: Kim S
Year: 2010
Journal: Eur J Immunol
Title: Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome.
Volume: 40
Issue: 6
Pages: 1545-51
Publication
First Author: Zhang H
Year: 2017
Journal: J Immunol
Title: AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality.
Volume: 198
Issue: 11
Pages: 4383-4393
UniProt Feature
Begin: 151
Description: AIM2
Type: short sequence motif
End: 154
Publication  
First Author: Kim H
Year: 2020
Journal: Brain Behav Immun
Title: AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice.
Volume: 87
Pages: 765-776
Publication
First Author: Jakobs C
Year: 2015
Journal: PLoS One
Title: AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis.
Volume: 10
Issue: 6
Pages: e0131702
Publication
First Author: Roberts TL
Year: 2009
Journal: Science
Title: HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA.
Volume: 323
Issue: 5917
Pages: 1057-60
Publication
First Author: Man SM
Year: 2016
Journal: Cell
Title: IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.
Volume: 167
Issue: 2
Pages: 382-396.e17
Publication
First Author: Man SM
Year: 2015
Journal: Cell
Title: Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer.
Volume: 162
Issue: 1
Pages: 45-58
Publication
First Author: Hu B
Year: 2016
Journal: Science
Title: The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury.
Volume: 354
Issue: 6313
Pages: 765-768
Publication
First Author: Wilson JE
Year: 2015
Journal: Nat Med
Title: Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt.
Volume: 21
Issue: 8
Pages: 906-13
Publication
First Author: Gong Z
Year: 2019
Journal: Diabetologia
Title: Deficiency in AIM2 induces inflammation and adipogenesis in white adipose tissue leading to obesity and insulin resistance.
Volume: 62
Issue: 12
Pages: 2325-2339
Publication
First Author: Hanamsagar R
Year: 2014
Journal: J Neurochem
Title: Critical role for the AIM2 inflammasome during acute CNS bacterial infection.
Volume: 129
Issue: 4
Pages: 704-11
Publication
First Author: Panchanathan R
Year: 2010
Journal: J Immunol
Title: Aim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.
Volume: 185
Issue: 12
Pages: 7385-93
Publication
First Author: Di Micco A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity.
Volume: 113
Issue: 32
Pages: E4671-80
Publication
First Author: Denes A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.
Volume: 112
Issue: 13
Pages: 4050-5
Publication
First Author: Ru H
Year: 2013
Journal: Cell Res
Title: Structural basis for termination of AIM2-mediated signaling by p202.
Volume: 23
Issue: 6
Pages: 855-8
Publication
First Author: Zhu Q
Year: 2018
Journal: Cell Rep
Title: Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection.
Volume: 22
Issue: 12
Pages: 3168-3174
Publication
First Author: Hu S
Year: 2015
Journal: Cell Rep
Title: The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense.
Volume: 13
Issue: 9
Pages: 1922-36
Publication
First Author: Kalantari P
Year: 2014
Journal: Cell Rep
Title: Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.
Volume: 6
Issue: 1
Pages: 196-210
Publication
First Author: Baum R
Year: 2015
Journal: J Immunol
Title: Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice.
Volume: 194
Issue: 3
Pages: 873-7
Publication
First Author: Zhu Q
Year: 2018
Journal: J Immunol
Title: Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against Francisella novicida.
Volume: 201
Issue: 12
Pages: 3662-3668
Publication
First Author: Man SM
Year: 2015
Journal: Nat Immunol
Title: The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.
Volume: 16
Issue: 5
Pages: 467-75
Publication
First Author: Karki R
Year: 2015
Journal: Cell Host Microbe
Title: Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection.
Volume: 17
Issue: 3
Pages: 357-368
Publication
First Author: Meunier E
Year: 2015
Journal: Nat Immunol
Title: Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.
Volume: 16
Issue: 5
Pages: 476-484
Publication
First Author: Sagulenko V
Year: 2013
Journal: Cell Death Differ
Title: AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.
Volume: 20
Issue: 9
Pages: 1149-60
Publication
First Author: Bürckstümmer T
Year: 2009
Journal: Nat Immunol
Title: An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.
Volume: 10
Issue: 3
Pages: 266-72
Publication
First Author: Komada T
Year: 2018
Journal: J Am Soc Nephrol
Title: Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD.
Volume: 29
Issue: 4
Pages: 1165-1181
Publication
First Author: Shah S
Year: 2013
Journal: J Immunol
Title: Cutting edge: Mycobacterium tuberculosis but not nonvirulent mycobacteria inhibits IFN-β and AIM2 inflammasome-dependent IL-1β production via its ESX-1 secretion system.
Volume: 191
Issue: 7
Pages: 3514-8
Publication
First Author: Liu F
Year: 2017
Journal: J Immunol
Title: Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor.
Volume: 199
Issue: 9
Pages: 3293-3305
Publication
First Author: Panchanathan R
Year: 2011
Journal: Mol Immunol
Title: Cell type and gender-dependent differential regulation of the p202 and Aim2 proteins: implications for the regulation of innate immune responses in SLE.
Volume: 49
Issue: 1-2
Pages: 273-80
Publication
First Author: Pierini R
Year: 2012
Journal: Cell Death Differ
Title: AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages.
Volume: 19
Issue: 10
Pages: 1709-21
Publication
First Author: Panchanathan R
Year: 2011
Journal: J Immunol
Title: Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility protein.
Volume: 186
Issue: 12
Pages: 6762-70
Publication
First Author: Feng S
Year: 2019
Journal: Innate Immun
Title: Absent in melanoma 2 inflammasome is required for host defence against Streptococcus pneumoniae infection.
Volume: 25
Issue: 7
Pages: 412-419
Publication
First Author: Maruzuru Y
Year: 2018
Journal: Cell Host Microbe
Title: Herpes Simplex Virus 1 VP22 Inhibits AIM2-Dependent Inflammasome Activation to Enable Efficient Viral Replication.
Volume: 23
Issue: 2
Pages: 254-265.e7
Publication
First Author: Su S
Year: 2018
Journal: Cell
Title: Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages.
Volume: 175
Issue: 2
Pages: 442-457.e23
Publication  
First Author: Nakaya Y
Year: 2017
Journal: MBio
Title: AIM2-Like Receptors Positively and Negatively Regulate the Interferon Response Induced by Cytosolic DNA.
Volume: 8
Issue: 4
Publication
First Author: Pierini R
Year: 2013
Journal: J Immunol
Title: ASC controls IFN-γ levels in an IL-18-dependent manner in caspase-1-deficient mice infected with Francisella novicida.
Volume: 191
Issue: 7
Pages: 3847-57
Publication
First Author: Shi CS
Year: 2012
Journal: Nat Immunol
Title: Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction.
Volume: 13
Issue: 3
Pages: 255-63
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Schattgen SA
Year: 2016
Journal: J Immunol
Title: Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2.
Volume: 196
Issue: 1
Pages: 29-33
Publication
First Author: Guo Y
Year: 2020
Journal: J Clin Invest
Title: HUWE1 mediates inflammasome activation and promotes host defense against bacterial infection.
Volume: 130
Issue: 12
Pages: 6301-6316
Publication
First Author: Li C
Year: 2018
Journal: Dev Cell
Title: PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.
Volume: 46
Issue: 4
Pages: 441-455.e8
Publication
First Author: Banerjee I
Year: 2018
Journal: Immunity
Title: Gasdermin D Restrains Type I Interferon Response to Cytosolic DNA by Disrupting Ionic Homeostasis.
Volume: 49
Issue: 3
Pages: 413-426.e5
Publication
First Author: Zhang T
Year: 2019
Journal: Biochem Biophys Res Commun
Title: NLRP3/ASC/Caspase-1 axis and serine protease activity are involved in neutrophil IL-1β processing during Streptococcus pneumoniae infection.
Volume: 513
Issue: 3
Pages: 675-680
Publication
First Author: Panchanathan R
Year: 2012
Journal: J Immunol
Title: Distinct regulation of murine lupus susceptibility genes by the IRF5/Blimp-1 axis.
Volume: 188
Issue: 1
Pages: 270-8
Publication
First Author: Wallet P
Year: 2017
Journal: PLoS Pathog
Title: IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection.
Volume: 13
Issue: 10
Pages: e1006630
Publication
First Author: Xiao J
Year: 2020
Journal: PLoS Biol
Title: Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.
Volume: 18
Issue: 8
Pages: e3000807
Publication
First Author: Periasamy S
Year: 2016
Journal: PLoS Pathog
Title: Inflammasome-Independent NLRP3 Restriction of a Protective Early Neutrophil Response to Pulmonary Tularemia.
Volume: 12
Issue: 12
Pages: e1006059
Publication
First Author: Tsuchiya K
Year: 2010
Journal: J Immunol
Title: Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes.
Volume: 185
Issue: 2
Pages: 1186-95
Publication
First Author: Ulland TK
Year: 2013
Journal: Infect Immun
Title: Francisella tularensis live vaccine strain folate metabolism and pseudouridine synthase gene mutants modulate macrophage caspase-1 activation.
Volume: 81
Issue: 1
Pages: 201-8
Publication  
First Author: Cridland JA
Year: 2012
Journal: BMC Evol Biol
Title: The mammalian PYHIN gene family: phylogeny, evolution and expression.
Volume: 12
Pages: 140
Publication
First Author: Greaney AJ
Year: 2020
Journal: J Leukoc Biol
Title: Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event.
Volume: 108
Issue: 3
Pages: 773-786
Publication
First Author: Ge J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking.
Volume: 109
Issue: 16
Pages: 6193-8
Publication
First Author: Gomes MT
Year: 2013
Journal: J Immunol
Title: Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.
Volume: 190
Issue: 7
Pages: 3629-38
Publication
First Author: Gray EE
Year: 2016
Journal: Immunity
Title: The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.
Volume: 45
Issue: 2
Pages: 255-66
Publication
First Author: Costa Franco MM
Year: 2018
Journal: J Immunol
Title: Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.
Volume: 200
Issue: 2
Pages: 607-622
Publication  
First Author: Robinson KM
Year: 2018
Journal: JCI Insight
Title: The inflammasome potentiates influenza/Staphylococcus aureus superinfection in mice.
Volume: 3
Issue: 7
Publication
First Author: Sivaraman V
Year: 2015
Journal: PLoS Pathog
Title: Yersinia pestis activates both IL-1β and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague.
Volume: 11
Issue: 3
Pages: e1004688
Publication
First Author: Wang Y
Year: 2017
Journal: Immunity
Title: Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection.
Volume: 46
Issue: 3
Pages: 393-404
Publication
First Author: Kailasan Vanaja S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome.
Volume: 111
Issue: 21
Pages: 7765-70