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Search results 1 to 98 out of 98 for Aipl1

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Hits by Category

Hits by Strain

Type Details Score
Gene
23746 | AIPL1
Type: gene
Organism: human
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Gene
100101778 | aipl1
Type: gene
Organism: frog, western clawed
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Gene
281609 | AIPL1
Type: gene
Organism: cattle
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Gene
59110 | Aipl1
Type: gene
Organism: rat
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Gene
489447 | AIPL1
Type: gene
Organism: dog, domestic
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Gene
468171 | AIPL1
Type: gene
Organism: chimpanzee
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Gene
769785 | AIPL1
Type: gene
Organism: chicken
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Gene
100537095 | aipl1
Type: gene
Organism: zebrafish
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Gene
574331 | AIPL1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2148800 | Aipl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR031209 | AIPL1
Type: Family
Description: Aryl-hydrocarbon-interacting protein-like 1 (AIPL1) appears to function as a photoreceptor-specific molecular chaperone. Mutations in the AIPL1 gene cause Leber's congenital amaurosis (LCA), which is characterised by profound visual impairment or loss at birth [].
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Publication
25274777 | J:218096
First Author: Ku CA
Year: 2015
Journal: Hum Mol Genet
Title: Viral-mediated vision rescue of a novel AIPL1 cone-rod dystrophy model.
Volume: 24
Issue: 3
Pages: 670-84
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Publication
25799540 | -
First Author: Hidalgo-de-Quintana J
Year: 2015
Journal: PLoS One
Title: The Leber congenital amaurosis protein AIPL1 and EB proteins co-localize at the photoreceptor cilium.
Volume: 10
Issue: 3
Pages: e0121440
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Publication
16639031 | J:108500
First Author: Makino CL
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: Effects of low AIPL1 expression on phototransduction in rods.
Volume: 47
Issue: 5
Pages: 2185-94
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Publication
12374762 | J:79616
First Author: Akey DT
Year: 2002
Journal: Hum Mol Genet
Title: The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1.
Volume: 11
Issue: 22
Pages: 2723-33
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Publication
19710705 | J:155729
First Author: Sun X
Year: 2010
Journal: Gene Ther
Title: Gene therapy with a promoter targeting both rods and cones rescues retinal degeneration caused by AIPL1 mutations.
Volume: 17
Issue: 1
Pages: 117-31
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Publication
19299492 | J:148547
First Author: Tan MH
Year: 2009
Journal: Hum Mol Genet
Title: Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors.
Volume: 18
Issue: 12
Pages: 2099-114
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Protein
I6L993
Organism: Mus musculus/domesticus
Length: 179  
Fragment?: false
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Protein
Q9CTQ3
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: true
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Protein
Q9JLP4
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
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Protein
Q924K1
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: false
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Publication
11420621 | J:70375
First Author: Sohocki MM
Year: 2001
Journal: Mamm Genome
Title: Comparative analysis of aryl-hydrocarbon receptor interacting protein-like 1 (Aipl1), a gene associated with inherited retinal disease in humans.
Volume: 12
Issue: 7
Pages: 566-8
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Publication
15365173 | J:92601
First Author: Liu X
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: AIPL1, the protein that is defective in Leber congenital amaurosis, is essential for the biosynthesis of retinal rod cGMP phosphodiesterase.
Volume: 101
Issue: 38
Pages: 13903-8
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Publication
15365178 | J:92617
First Author: Ramamurthy V
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Leber congenital amaurosis linked to AIPL1: a mouse model reveals destabilization of cGMP phosphodiesterase.
Volume: 101
Issue: 38
Pages: 13897-902
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Publication
14555765 | J:92982
First Author: Ramamurthy V
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: AIPL1, a protein implicated in Leber's congenital amaurosis, interacts with and aids in processing of farnesylated proteins.
Volume: 100
Issue: 22
Pages: 12630-5
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Publication
15582159 | J:94655
First Author: Dyer MA
Year: 2004
Journal: Brain Res Mol Brain Res
Title: Retinal degeneration in Aipl1-deficient mice: a new genetic model of Leber congenital amaurosis.
Volume: 132
Issue: 2
Pages: 208-20
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Publication
27268253 | J:235796
First Author: Gopalakrishna KN
Year: 2016
Journal: J Biol Chem
Title: Aryl Hydrocarbon Receptor-interacting Protein-like 1 Is an Obligate Chaperone of Phosphodiesterase 6 and Is Assisted by the γ-Subunit of Its Client.
Volume: 291
Issue: 31
Pages: 16282-91
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Publication
20042464 | J:157652
First Author: Kirschman LT
Year: 2010
Journal: Hum Mol Genet
Title: The Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cells.
Volume: 19
Issue: 6
Pages: 1076-87
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Publication
24108108 | J:205988
First Author: Kolandaivelu S
Year: 2014
Journal: Hum Mol Genet
Title: AIPL1, A protein linked to blindness, is essential for the stability of enzymes mediating cGMP metabolism in cone photoreceptor cells.
Volume: 23
Issue: 4
Pages: 1002-12
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Publication
35065964 | J:343953
First Author: Yadav RP
Year: 2022
Journal: J Biol Chem
Title: Molecular insights into the maturation of phosphodiesterase 6 by the specialized chaperone complex of HSP90 with AIPL1.
Volume: 298
Issue: 3
Pages: 101620
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Publication
31488544 | J:282860
First Author: Yadav RP
Year: 2019
Journal: J Biol Chem
Title: Interaction of the tetratricopeptide repeat domain of aryl hydrocarbon receptor-interacting protein-like 1 with the regulatory Pγ subunit of phosphodiesterase 6.
Volume: 294
Issue: 43
Pages: 15795-15807
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Publication
19758987 | J:156330
First Author: Kolandaivelu S
Year: 2009
Journal: J Biol Chem
Title: AIPL1, a protein associated with childhood blindness, interacts with alpha-subunit of rod phosphodiesterase (PDE6) and is essential for its proper assembly.
Volume: 284
Issue: 45
Pages: 30853-61
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Protein Coding Gene
MGP_CAROLIEiJ_G0016661 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018627 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0018595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0018564 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0018567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0018380 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2148800 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019018 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017935 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0018461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0018452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0018532 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0018475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017708 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017989 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017794 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0017498 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
24736053 | J:229871
First Author: Singh RK
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Early alteration of retinal neurons in Aipl1-/- animals.
Volume: 55
Issue: 5
Pages: 3081-92
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Publication
27541351 | J:235590
First Author: Murphy D
Year: 2016
Journal: PLoS Genet
Title: The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina.
Volume: 12
Issue: 8
Pages: e1006256
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Publication
32375026 | J:293105
First Author: Bisbach CM
Year: 2020
Journal: Cell Rep
Title: Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O2-Rich Pigment Epithelium.
Volume: 31
Issue: 5
Pages: 107606
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Publication
21421996 | J:171632
First Author: Colella P
Year: 2011
Journal: Hum Mol Genet
Title: Non-erythropoietic erythropoietin derivatives protect from light-induced and genetic photoreceptor degeneration.
Volume: 20
Issue: 11
Pages: 2251-62
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Publication
21555557 | J:171900
First Author: Christiansen JR
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments.
Volume: 108
Issue: 21
Pages: 8862-6
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Publication
28859131 | J:243745
First Author: Krebs MP
Year: 2017
Journal: PLoS One
Title: Mouse models of human ocular disease for translational research.
Volume: 12
Issue: 8
Pages: e0183837
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Publication
25776555 | J:224407
First Author: Murphy D
Year: 2015
Journal: Mol Cell Biol
Title: Alternative Splicing Shapes the Phenotype of a Mutation in BBS8 To Cause Nonsyndromic Retinitis Pigmentosa.
Volume: 35
Issue: 10
Pages: 1860-70
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Publication
33500475 | J:301112
First Author: Maddala R
Year: 2021
Journal: Sci Rep
Title: Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract.
Volume: 11
Issue: 1
Pages: 2203
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Aipl1<em1Smoc> | MGI:7288205
Name: aryl hydrocarbon receptor-interacting protein-like 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6474750 | C57BL/6JSmoc-Aipl1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Aipl1<tm1Tili> | MGI:3054784
Name: aryl hydrocarbon receptor-interacting protein-like 1; targeted mutation 1, Tiansen Li
Allele Type: Targeted
Attribute String: Hypomorph
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Allele
Aipl1<tm1Visu> | MGI:3054793
Name: aryl hydrocarbon receptor-interacting protein-like 1; targeted mutation 1, Visvanathan Ramamurthy
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Aipl1<tm1Mad> | MGI:3524971
Name: aryl hydrocarbon receptor-interacting protein-like 1; targeted mutation 1, Michael A Dyer
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Aipl1<tvrm119> | MGI:5810589
Name: aryl hydrocarbon receptor-interacting protein-like 1; translational vision research model 119
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Aipl1<tvrm127> | MGI:5810590
Name: aryl hydrocarbon receptor-interacting protein-like 1; translational vision research model 127
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Allele
Tg(Crx-AIPL1*P351)#Visu | MGI:5621018
Name: transgene insertion, Visvanathan Ramamurthy
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Aipl1/Aipl1
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aipl1/Aipl1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aipl1/Aipl1
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110332 | Leber congenital amaurosis 4
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Genotype
Genotype
Symbol: Aipl1/Aipl1
Background: C57BL/6J-Aipl1/Pjn
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aipl1/Aipl1
Background: C57BL/6J-Aipl1/Pjn
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aipl1/Aipl1 Tg(Crx-AIPL1*P351)#Visu/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Publication
22784109 | J:190581
First Author: Ochocinska MJ
Year: 2012
Journal: J Neurochem
Title: NeuroD1 is required for survival of photoreceptors but not pinealocytes: results from targeted gene deletion studies.
Volume: 123
Issue: 1
Pages: 44-59
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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