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Search results 1 to 100 out of 250 for Akap13

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0.038s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: A-kinase anchor protein 13 (AKAP13, also known as AKAP-Lbc) belongs to the AKAP family, which contains functionally related proteins involved in the targeting of the PKA holoenzyme towards specific physiological substrates []. AKAP13 anchors cAMP-dependent protein kinase (PKA) and acts as a guanine nucleotide exchange factor (GEF) that activates the GTPase RhoA []. The Rho-GEF activity of AKAP13 can be inhibited by protein 14-3-3 when it adopts an oligomeric conformation []. AKAP13 has been shown to be essential for cardiac development in mice []. It also plays a role in osteogenesis [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Koide H
Year: 2015
Journal: J Bone Miner Res
Title: Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis.
Volume: 30
Issue: 10
Pages: 1887-95
Publication
First Author: Mayers CM
Year: 2010
Journal: J Biol Chem
Title: The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice.
Volume: 285
Issue: 16
Pages: 12344-54
Publication
First Author: Spindler MJ
Year: 2013
Journal: PLoS One
Title: AKAP13 Rho-GEF and PKD-binding domain deficient mice develop normally but have an abnormal response to β-adrenergic-induced cardiac hypertrophy.
Volume: 8
Issue: 4
Pages: e62705
Publication  
First Author: Taglieri DM
Year: 2014
Journal: J Mol Cell Cardiol
Title: The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.
Volume: 66
Pages: 27-40
Protein
Organism: Mus musculus
Length: 228  
Fragment?: false
Protein
Organism: Mus musculus
Length: 423  
Fragment?: true
Protein
Organism: Mus musculus
Length: 186  
Fragment?: true
Protein
Organism: Mus musculus
Length: 870  
Fragment?: true
Protein
Organism: Mus musculus
Length: 238  
Fragment?: false
Protein
Organism: Mus musculus
Length: 934  
Fragment?: true
Protein
Organism: Mus musculus
Length: 121  
Fragment?: true
Protein
Organism: Mus musculus
Length: 569  
Fragment?: true
Publication
First Author: Diviani D
Year: 2001
Journal: J Biol Chem
Title: AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation.
Volume: 276
Issue: 47
Pages: 44247-57
Publication
First Author: Diviani D
Year: 2006
Journal: Eur J Cell Biol
Title: AKAP-Lbc: a molecular scaffold for the integration of cyclic AMP and Rho transduction pathways.
Volume: 85
Issue: 7
Pages: 603-10
Protein
Organism: Mus musculus
Length: 108  
Fragment?: false
Protein
Organism: Mus musculus
Length: 360  
Fragment?: true
Protein
Organism: Mus musculus
Length: 345  
Fragment?: true
Protein
Organism: Mus musculus
Length: 2776  
Fragment?: false
Protein
Organism: Mus musculus
Length: 607  
Fragment?: true
Protein
Organism: Mus musculus
Length: 2794  
Fragment?: false
Protein
Organism: Mus musculus
Length: 607  
Fragment?: true
Publication
First Author: Johnson KR
Year: 2015
Journal: PLoS One
Title: Genome-Wide Gene Expression Analysis Shows AKAP13-Mediated PKD1 Signaling Regulates the Transcriptional Response to Cardiac Hypertrophy.
Volume: 10
Issue: 7
Pages: e0132474
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Tsuchiya T
Year: 1992
Journal: Biochem Biophys Res Commun
Title: In vitro reconstitution of an erythropoietin gene transcription system using its 5'-flanking sequence and a nuclear extract from anemic kidney.
Volume: 182
Issue: 1
Pages: 137-43
GXD Expression    
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672827
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5816371
Assay Type: Northern blot
Annotation Date: 2017-01-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5816372
Age: postnatal
Image: 1
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5775093
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775129
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5775095
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775141
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5775096
Assay Type: RT-PCR
Annotation Date: 2016-06-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:5775143
Age: postnatal newborn
Image: 5
Detected: false
Specimen Num: 6