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Search results 1 to 93 out of 93 for Akap3

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Hits by Category

Hits by Strain

Type Details Score
Gene
10566 | AKAP3
Type: gene
Organism: human
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Gene
281610 | AKAP3
Type: gene
Organism: cattle
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Gene
312720 | Akap3
Type: gene
Organism: rat
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Gene
466927 | AKAP3
Type: gene
Organism: chimpanzee
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Gene
477719 | AKAP3
Type: gene
Organism: dog, domestic
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Gene
711162 | AKAP3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1341149 | Akap3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24648398 | J:212774
First Author: Xu K
Year: 2014
Journal: Biol Reprod
Title: AKAP3 synthesis is mediated by RNA binding proteins and PKA signaling during mouse spermiogenesis.
Volume: 90
Issue: 6
Pages: 119
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Publication
31969357 | J:284173
 
First Author: Xu K
Year: 2020
Journal: Development
Title: Lack of AKAP3 disrupts integrity of the subcellular structure and proteome of mouse sperm and causes male sterility.
Volume: 147
Issue: 2
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Publication
24687590 | J:213649
First Author: Xu K
Year: 2014
Journal: Mol Reprod Dev
Title: Sperm-specific AKAP3 is a dual-specificity anchoring protein that interacts with both protein kinase a regulatory subunits via conserved N-terminal amphipathic peptides.
Volume: 81
Issue: 7
Pages: 595-607
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Publication
12606363 | J:83525
First Author: Brown PR
Year: 2003
Journal: Biol Reprod
Title: A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.
Volume: 68
Issue: 6
Pages: 2241-8
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Publication
15257753 | J:218814
 
First Author: Lea IA
Year: 2004
Journal: Reprod Biol Endocrinol
Title: Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella.
Volume: 2
Pages: 57
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Publication
25820252 | J:227444
 
First Author: Fatima S
Year: 2015
Journal: Sci Rep
Title: Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.
Volume: 5
Pages: 9459
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Protein Coding Gene
MGP_CAROLIEiJ_G0028889 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031277 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031205 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031284 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0031008 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1341149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031741 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030389 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030969 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0031125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0031074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031205 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0031113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031776 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0030104 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022650 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029933 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5919938
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:5925262
Age: embryonic day 0.5
Image: 5
Specimen Label: Zy
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5919938
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:5925262
Age: embryonic day 1.0
Image: 5
Specimen Label: 2c
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5919938
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360633
Stage: TS03
Assay Id: MGI:5925262
Age: embryonic day 2.5
Image: 5
Specimen Label: 4/8c
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5919938
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:5925262
Age: embryonic day 3.0
Image: 5
Specimen Label: Mo
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5919938
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5925262
Age: embryonic day 3.5
Image: 5
Specimen Label: Bl
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5919938
Assay Type: RT-PCR
Annotation Date: 2017-11-16
Strength: Present
Sex: Female
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:5925262
Age: postnatal
Image: 5
Specimen Label: MII
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: 8Ba
Specimen Label: 8Ba
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: 8Bb
Note: Expression is in the fibrous sheath.
Specimen Label: 8Bb
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: 8Bc
Note: Expression is in the fibrous sheath.
Specimen Label: 8Bc
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: 8Bd
Note: Expression is in the fibrous sheath.
Specimen Label: 8Bd
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: 8Be
Note: Expression is in the fibrous sheath.
Specimen Label: 8Be
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: 8Bf
Note: Expression is in the fibrous sheath.
Specimen Label: 8Bf
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Ba
Note: Expression is in the fibrous sheath.
Specimen Label: S6Ba
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bb
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bb
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bc
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bc
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bd
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bd
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Be
Note: Expression is in the fibrous sheath.
Specimen Label: S6Be
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bf
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bf
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bg
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bg
Detected: true
Specimen Num: 15
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bh
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bh
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bi
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bi
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bj
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bj
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal
Image: S6Bk
Note: Expression is in the fibrous sheath.
Specimen Label: S6Bk
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal month 6
Image: 7Cb
Note: Expression is in the fibrous sheath.
Specimen Label: 7Cb
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5823961
Assay Type: Immunohistochemistry
Annotation Date: 2017-02-11
Strength: Present
Sex: Male
Emaps: EMAPS:3148828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5823968
Age: postnatal month 6
Image: 7Ch
Note: Expression is in the fibrous sheath. 111/139 spermatozoa have ectopic fibrous sheath in the midpiece region close to the sperm head.
Specimen Label: 7Ch
Detected: true
Specimen Num: 2
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Publication
10319321 | J:54430
First Author: Vijayaraghavan S
Year: 1999
Journal: Mol Endocrinol
Title: Isolation and molecular characterization of AKAP110, a novel, sperm-specific protein kinase A-anchoring protein.
Volume: 13
Issue: 5
Pages: 705-17
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Publication
11278869 | J:69494
First Author: Carr DW
Year: 2001
Journal: J Biol Chem
Title: Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA.
Volume: 276
Issue: 20
Pages: 17332-8
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Publication
20731842 | J:170225
 
First Author: Li YF
Year: 2010
Journal: Reprod Biol Endocrinol
Title: CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath.
Volume: 8
Pages: 101
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Publication
37709195 | J:345053
     
First Author: Wang Y
Year: 2023
Journal: J Genet Genomics
Title: Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice.
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Publication
27965440 | J:237484
First Author: Weidemann M
Year: 2016
Journal: Development
Title: CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.
Volume: 143
Issue: 24
Pages: 4736-4748
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Publication
31884020 | J:286555
First Author: Rachev E
Year: 2020
Journal: Dev Biol
Title: CFAP43 modulates ciliary beating in mouse and Xenopus.
Volume: 459
Issue: 2
Pages: 109-125
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Publication
33666296 | J:306880
First Author: Xia Q
Year: 2021
Journal: Cell Prolif
Title: RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes.
Volume: 54
Issue: 5
Pages: e13000
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Publication
16687649 | J:111771
First Author: Krisfalusi M
Year: 2006
Journal: Biol Reprod
Title: Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa.
Volume: 75
Issue: 2
Pages: 270-8
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Publication
27869233 | J:244597
 
First Author: Cui W
Year: 2016
Journal: Sci Rep
Title: Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos.
Volume: 6
Pages: 37396
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0070581 | spermatogenic failure 82
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Protein
Q9D3V5
Organism: Mus musculus/domesticus
Length: 435  
Fragment?: false
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Protein
A0A2R8W6Q5
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein Domain
IPR026246 | Fsip1
Type: Family
Description: Found in the main part of the sperm flagellum, the fibrous sheath is a cytoskeletal structure comprising two longitudinal columns connected by closely spaced circumferential ribs []. A-kinase anchoring proteins (AKAPs) secure cyclic AMP-dependent protein kinases within specific cytoplasmic domains; most abundant in the fibrous sheath is AKAP4 []. AKAP4 has been shown to bind AKAP3 and two spermatogenic cell-specific proteins, Fibrous Sheath Interacting Proteins 1 and 2 (FSIP1, FSIP2) [].How the fibrous sheath assembles is not yet fully understood. AKAP4 is synthesised and incorporated into the nascent fibrous sheath late in spermatid development; its precursor is processed in the flagellum, and only the mature form of AKAP4 appears to bind AKAP3 []. It is likely, therefore, that AKAP3 is involved in organising the basic structure of the fibrous sheath, while AKAP4 helps to complete fibrous sheath assembly.The FSIP1 protein is 435 amino acids in length, and is rich in glutamine and asparagine []. Minimum domains for its binding to AKAP4 have been localised to amino acids 351-359 and 692-721 of AKAP4 constructs [].
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Publication
23303679 | J:206637
First Author: Fiedler SE
Year: 2013
Journal: Biol Reprod
Title: Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity.
Volume: 88
Issue: 2
Pages: 41
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Publication
36792588 | J:340653
First Author: Wu H
Year: 2023
Journal: Cell Death Dis
Title: DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath.
Volume: 14
Issue: 2
Pages: 127
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