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Search results 1 to 71 out of 71 for Akap4

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Miki K
Year: 2002
Journal: Dev Biol
Title: Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility.
Volume: 248
Issue: 2
Pages: 331-42
Publication
First Author: Fang X
Year: 2019
Journal: Dev Biol
Title: Proteomics and single-cell RNA analysis of Akap4-knockout mice model confirm indispensable role of Akap4 in spermatogenesis.
Volume: 454
Issue: 2
Pages: 118-127
Publication
First Author: Brown PR
Year: 2003
Journal: Biol Reprod
Title: A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.
Volume: 68
Issue: 6
Pages: 2241-8
Publication
First Author: Nipper RW
Year: 2006
Journal: Biol Reprod
Title: Protein domains govern the intracellular distribution of mouse sperm AKAP4.
Volume: 75
Issue: 2
Pages: 189-96
Publication  
First Author: Xu K
Year: 2020
Journal: Development
Title: Lack of AKAP3 disrupts integrity of the subcellular structure and proteome of mouse sperm and causes male sterility.
Volume: 147
Issue: 2
Publication
First Author: Huang Z
Year: 2005
Journal: Biol Reprod
Title: Changes in intracellular distribution and activity of protein phosphatase PP1gamma2 and its regulating proteins in spermatozoa lacking AKAP4.
Volume: 72
Issue: 2
Pages: 384-92
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Carrera A
Year: 1994
Journal: Dev Biol
Title: The major fibrous sheath polypeptide of mouse sperm: structural and functional similarities to the A-kinase anchoring proteins.
Volume: 165
Issue: 1
Pages: 272-84
Publication
First Author: Fulcher KD
Year: 1995
Journal: Biol Reprod
Title: Characterization of Fsc1 cDNA for a mouse sperm fibrous sheath component.
Volume: 52
Issue: 1
Pages: 41-9
Publication
First Author: Turner RM
Year: 1998
Journal: J Biol Chem
Title: An X-linked gene encodes a major human sperm fibrous sheath protein, hAKAP82. Genomic organization, protein kinase A-RII binding, and distribution of the precursor in the sperm tail.
Volume: 273
Issue: 48
Pages: 32135-41
Publication
First Author: Jha KN
Year: 2002
Journal: Mol Reprod Dev
Title: Identification of the major tyrosine phosphorylated protein of capacitated hamster spermatozoa as a homologue of mammalian sperm a kinase anchoring protein.
Volume: 61
Issue: 2
Pages: 258-70
Publication
First Author: Vijayaraghavan S
Year: 1999
Journal: Mol Endocrinol
Title: Isolation and molecular characterization of AKAP110, a novel, sperm-specific protein kinase A-anchoring protein.
Volume: 13
Issue: 5
Pages: 705-17
Publication
First Author: Sironen A
Year: 2011
Journal: Biol Reprod
Title: Loss of SPEF2 function in mice results in spermatogenesis defects and primary ciliary dyskinesia.
Volume: 85
Issue: 4
Pages: 690-701
Publication
First Author: Moss SB
Year: 1997
Journal: Mamm Genome
Title: Mapping of a haploid transcribed and translated sperm-specific gene to the mouse X chromosome.
Volume: 8
Issue: 1
Pages: 37-8
Publication
First Author: Nakamura Y
Year: 2002
Journal: Biol Reprod
Title: Molecular cloning and characterization of oppo 1: a haploid germ cell-specific complementary DNA encoding sperm tail protein.
Volume: 67
Issue: 1
Pages: 1-7
Publication  
First Author: Li YF
Year: 2010
Journal: Reprod Biol Endocrinol
Title: CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath.
Volume: 8
Pages: 101
Publication
First Author: Miki K
Year: 1998
Journal: J Biol Chem
Title: Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1.
Volume: 273
Issue: 51
Pages: 34384-90
Publication
First Author: Faul C
Year: 2007
Journal: Mol Cell Biol
Title: Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.
Volume: 27
Issue: 23
Pages: 8215-27
Publication
First Author: Riddle RC
Year: 2013
Journal: PLoS One
Title: Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition.
Volume: 8
Issue: 5
Pages: e63323
Publication
First Author: Sutton KA
Year: 1997
Journal: Genomics
Title: The rapidly evolving Pem homeobox gene and Agtr2, Ant2, and Lamp2 are closely linked in the proximal region of the mouse X chromosome.
Volume: 45
Issue: 2
Pages: 447-50
Publication
First Author: Krisfalusi M
Year: 2006
Journal: Biol Reprod
Title: Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa.
Volume: 75
Issue: 2
Pages: 270-8
Publication  
First Author: Scovell JM
Year: 2021
Journal: Development
Title: PRSS50 is a testis protease responsible for proper sperm tail formation and function.
Volume: 148
Issue: 8
Publication
First Author: Means GD
Year: 2000
Journal: Genomics
Title: A transcript map of a 2-Mb BAC contig in the proximal portion of the mouse X chromosome and regional mapping of the scurfy mutation.
Volume: 65
Issue: 3
Pages: 213-23
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein
Organism: Mus musculus/domesticus
Length: 435  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
Protein Domain
Type: Family
Description: Found in the main part of the sperm flagellum, the fibrous sheath is a cytoskeletal structure comprising two longitudinal columns connected by closely spaced circumferential ribs []. A-kinase anchoring proteins (AKAPs) secure cyclic AMP-dependent protein kinases within specific cytoplasmic domains; most abundant in the fibrous sheath is AKAP4 []. AKAP4 has been shown to bind AKAP3 and two spermatogenic cell-specific proteins, Fibrous Sheath Interacting Proteins 1 and 2 (FSIP1, FSIP2) [].How the fibrous sheath assembles is not yet fully understood. AKAP4 is synthesised and incorporated into the nascent fibrous sheath late in spermatid development; its precursor is processed in the flagellum, and only the mature form of AKAP4 appears to bind AKAP3 []. It is likely, therefore, that AKAP3 is involved in organising the basic structure of the fibrous sheath, while AKAP4 helps to complete fibrous sheath assembly.The FSIP1 protein is 435 amino acids in length, and is rich in glutamine and asparagine []. Minimum domains for its binding to AKAP4 have been localised to amino acids 351-359 and 692-721 of AKAP4 constructs [].
Publication
First Author: Silva JV
Year: 2017
Journal: Biochim Biophys Acta
Title: Construction and analysis of a human testis/sperm-enriched interaction network: Unraveling the PPP1CC2 interactome.
Volume: 1861
Issue: 2
Pages: 375-385
Publication  
First Author: Lea IA
Year: 2004
Journal: Reprod Biol Endocrinol
Title: Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella.
Volume: 2
Pages: 57