Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents aldo-keto reductase family 1 member D1 (AKR1D1). It catalyses the stereospecific NADPH-dependent reduction of the C4-C5 double bond of bile acid intermediates and steroid hormones carrying a delta-4-3-one structure to yield an A/B cis-ring junction. This cis-configuration is crucial for bile acid biosynthesis and plays important roles in steroid metabolism []. It is capable of reducing a broad range of delta-4-3-ketosteroids from C18 (such as, 17beta-hydroxyestr-4-en-3-one) to C27 (such as, 7alpha-hydroxycholest-4-en-3-one) [].In general, the aldo-keto reductase (AKR) protein superfamily members reduce carbonyl substrates such as: sugar aldehydes, keto-steroids, keto-prostaglandins, retinals, quinones, and lipid peroxidation by-products [, ]. However, there are some exceptions, such as the reduction of steroid double bonds catalysed by AKR1D enzymes (5beta-reductases); and the oxidation of proximate carcinogen trans-dihydrodiol polycyclic aromatic hydrocarbons; while the beta-subunits of potassium gated ion channels (AKR6 family) control Kv channel opening [].Structurally, they contain an (alpha/beta)8-barrel motif, display large loops at the back of the barrel which govern substrate specificity, and have a conserved cofactor binding domain. The binding site is located in a large, deep, elliptical pocket in the C-terminal end of the beta sheet, the substrate being bound in an extended conformation. The hydrophobic nature of the pocket favours aromatic and apolar substrates over highly polar ones []. They catalyse an ordered bi bi kinetic mechanism in which NAD(P)H cofactor binds first and leaves last []. Binding of the NADPH coenzyme causes a massive conformational change, reorienting a loop, effectively locking the coenzyme in place. This binding is more similar to FAD- than to NAD(P)-binding oxidoreductases []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Gathercole LL |
Year: |
2022 |
Journal: |
J Endocrinol |
Title: |
AKR1D1 knockout mice develop a sex-dependent metabolic phenotype. |
Volume: |
253 |
Issue: |
3 |
Pages: |
97-113 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
325
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Bohren KM |
Year: |
1989 |
Journal: |
J Biol Chem |
Title: |
The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases. |
Volume: |
264 |
Issue: |
16 |
Pages: |
9547-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borhani DW |
Year: |
1992 |
Journal: |
J Biol Chem |
Title: |
The crystal structure of the aldose reductase.NADPH binary complex. |
Volume: |
267 |
Issue: |
34 |
Pages: |
24841-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson DK |
Year: |
1992 |
Journal: |
Science |
Title: |
An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications. |
Volume: |
257 |
Issue: |
5066 |
Pages: |
81-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Penning TM |
Year: |
2015 |
Journal: |
Chem Biol Interact |
Title: |
The aldo-keto reductases (AKRs): Overview. |
Volume: |
234 |
|
Pages: |
236-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Di Costanzo L |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Crystal structure of human liver Delta4-3-ketosteroid 5beta-reductase (AKR1D1) and implications for substrate binding and catalysis. |
Volume: |
283 |
Issue: |
24 |
Pages: |
16830-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen M |
Year: |
2011 |
Journal: |
Steroids |
Title: |
Substrate specificity and inhibitor analyses of human steroid 5β-reductase (AKR1D1). |
Volume: |
76 |
Issue: |
5 |
Pages: |
484-90 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3516422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1760622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1876728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370828 |
|
Specimen Label: |
JAX_1370828 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737322 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1737328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370843 |
Note: |
kidney |
Specimen Label: |
JAX_1370843 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666522 |
Pattern: |
Ubiquitous |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3267828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370827 |
|
Specimen Label: |
JAX_1370827 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754922 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the corpus striatum (lateral ganglionic eminence). |
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1697422 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the face/soft tissues. |
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1783822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1665922 |
Pattern: |
Ubiquitous |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1706822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1706828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370830 |
|
Specimen Label: |
JAX_1370830 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1674822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1670622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1654222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1777922 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684922 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1716822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1755022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1733122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1736622 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
Note: |
Expression was strong in the genito-urinary system. |
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610422 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876922 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1925228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370836 |
|
Specimen Label: |
JAX_1370836 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1619422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3290622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1795022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1745822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3278022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the pallidum (medial ganglionic eminence). |
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3286922 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778722 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3267222 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1672828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370835 |
|
Specimen Label: |
JAX_1370835 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1853522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1666822 |
Pattern: |
Ubiquitous |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689622 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610522 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1647022 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1842622 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1842628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370844 |
|
Specimen Label: |
JAX_1370844 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3277822 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3090122 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1685322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1685328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370831 |
|
Specimen Label: |
JAX_1370831 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5310505 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
Pattern: |
Ubiquitous |
Stage: |
TS22 |
Assay Id: |
MGI:5423828 |
Age: |
embryonic day 14.5 |
Image: |
EH1341; Specimen C2631 |
|
Specimen Label: |
EH1341; Specimen C2631 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1684628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692528 |
Age: |
postnatal adult |
Image: |
JAX_1370842 |
|
Specimen Label: |
JAX_1370842 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|