|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 2731 for Akt1

<< First    < Previous  |  Next >    Last >>
0.054s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
key_1584413 | Akt1
Type: gene
Organism: Not Specified
•
•
•
•
•
Gene
207 | AKT1
Type: gene
Organism: human
•
•
•
•
•
Gene
100490038 | akt1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
24185 | Akt1
Type: gene
Organism: rat
•
•
•
•
•
Gene
490878 | AKT1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
740898 | AKT1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
280991 | AKT1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
395928 | AKT1
Type: gene
Organism: chicken
•
•
•
•
•
Gene
697747 | AKT1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
101910198 | akt1
Type: gene
Organism: zebrafish
•
•
•
•
•
Protein Domain
IPR034676 | Akt1
Type: Domain
Description: Protein kinase B alpha (PKB-alpha), also known as AKT1, is one of three closely related serine/threonine-protein kinases: AKT1/alpha, AKT2/beta and AKT3/gamma. PKBs contain an N-terminal pleckstrin homology (PH) domain and a C-terminal catalytic domain []. PKB-alpha is predominantly expressed in endothelial cells. It is critical for the regulation of angiogenesis and the maintenance of vascular integrity []. It also plays a role in adipocyte differentiation []. Mice deficient in PKB-alpha exhibit perinatal morbidity, growth retardation, reduction in body weight accompanied by reduced sizes of multiple organs, and enhanced apoptosis in some cell types. PKB-alpha activity has been reported to be frequently elevated in breast and prostate cancers [, ]. In some cancer cells, PKB-alpha may act as a suppressor of metastasis [].
•
•
•
•
•
Protein Coding Gene
MGI:87986 | Akt1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
17460049 | J:121297
First Author: Ju X
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Akt1 governs breast cancer progression in vivo.
Volume: 104
Issue: 18
Pages: 7438-43
•
•
•
•
•
Gene
84335 | AKT1S1
Type: gene
Organism: human
•
•
•
•
•
Publication
14973226 | J:116239
First Author: Saito A
Year: 2004
Journal: J Neurosci
Title: Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor.
Volume: 24
Issue: 7
Pages: 1584-93
•
•
•
•
•
Publication
16552185 | -
First Author: Somanath PR
Year: 2006
Journal: Cell Cycle
Title: Akt1 in endothelial cell and angiogenesis.
Volume: 5
Issue: 5
Pages: 512-8
•
•
•
•
•
Protein
P31750
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
•
•
•
•
•
Publication
16397181 | J:116422
First Author: Saito A
Year: 2006
Journal: Stroke
Title: Modulation of proline-rich akt substrate survival signaling pathways by oxidative stress in mouse brains after transient focal cerebral ischemia.
Volume: 37
Issue: 2
Pages: 513-7
•
•
•
•
•
Publication
16338656 | -
First Author: Wyszomierski SL
Year: 2005
Journal: Cancer Cell
Title: A knotty turnabout?: Akt1 as a metastasis suppressor.
Volume: 8
Issue: 6
Pages: 437-9
•
•
•
•
•
Publication
9742206 | -
 
First Author: Coffer PJ
Year: 1998
Journal: Biochem J
Title: Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.
Volume: 335 ( Pt 1)
Pages: 1-13
•
•
•
•
•
Publication
10827191 | -
First Author: Graff JR
Year: 2000
Journal: J Biol Chem
Title: Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression.
Volume: 275
Issue: 32
Pages: 24500-5
•
•
•
•
•
Publication
15192111 | -
First Author: Xu J
Year: 2004
Journal: J Biol Chem
Title: Protein kinase B/AKT 1 plays a pivotal role in insulin-like growth factor-1 receptor signaling induced 3T3-L1 adipocyte differentiation.
Volume: 279
Issue: 34
Pages: 35914-22
•
•
•
•
•
Protein
Q9D1F4
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
•
•
•
•
•
Protein
E9QKI4
Organism: Mus musculus/domesticus
Length: 328  
Fragment?: false
•
•
•
•
•
Protein
E9QKI5
Organism: Mus musculus/domesticus
Length: 283  
Fragment?: false
•
•
•
•
•
Protein
D3YWZ1
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
•
•
•
•
•
Protein
F6R8S6
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: true
•
•
•
•
•
Protein
A0A140LHA0
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
•
•
•
•
•
Publication
16636172 | J:122451
First Author: DeBosch B
Year: 2006
Journal: Circulation
Title: Akt1 is required for physiological cardiac growth.
Volume: 113
Issue: 17
Pages: 2097-104
•
•
•
•
•
Publication
26565903 | J:228953
First Author: Cho JH
Year: 2015
Journal: Cell Rep
Title: AKT1 Activation Promotes Development of Melanoma Metastases.
Volume: 13
Issue: 5
Pages: 898-905
•
•
•
•
•
Publication
36269831 | J:345088
First Author: Demir S
Year: 2022
Journal: Sci Adv
Title: TSC22D4 interacts with Akt1 to regulate glucose metabolism.
Volume: 8
Issue: 42
Pages: eabo5555
•
•
•
•
•
Publication
20042722 | J:160279
First Author: Calamito M
Year: 2010
Journal: Blood
Title: Akt1 and Akt2 promote peripheral B-cell maturation and survival.
Volume: 115
Issue: 20
Pages: 4043-50
•
•
•
•
•
Publication
16763066 | J:129523
First Author: Rasoulpour T
Year: 2006
Journal: Endocrinology
Title: Akt1 suppresses radiation-induced germ cell apoptosis in vivo.
Volume: 147
Issue: 9
Pages: 4213-21
•
•
•
•
•
Publication
23935948 | J:204947
First Author: Nojima A
Year: 2013
Journal: PLoS One
Title: Haploinsufficiency of akt1 prolongs the lifespan of mice.
Volume: 8
Issue: 7
Pages: e69178
•
•
•
•
•
Publication
17957242 | J:130281
First Author: Kawamura N
Year: 2007
Journal: PLoS One
Title: Akt1 in osteoblasts and osteoclasts controls bone remodeling.
Volume: 2
Issue: 10
Pages: e1058
•
•
•
•
•
Publication
21242979 | J:170765
First Author: Hollander MC
Year: 2011
Journal: Oncogene
Title: Akt1 deletion prevents lung tumorigenesis by mutant K-ras.
Volume: 30
Issue: 15
Pages: 1812-21
•
•
•
•
•
Publication
20530873 | J:163718
First Author: Eke I
Year: 2010
Journal: J Clin Invest
Title: PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alpha.
Volume: 120
Issue: 7
Pages: 2516-27
•
•
•
•
•
Publication
22885182 | J:188140
First Author: Choi YH
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Akt1 regulates phosphorylation and osteogenic activity of Dlx3.
Volume: 425
Issue: 4
Pages: 800-5
•
•
•
•
•
Publication
31299858 | J:293589
First Author: Nie Y
Year: 2019
Journal: Innate Immun
Title: Akt1 regulates pulmonary fibrosis via modulating IL-13 expression in macrophages.
Volume: 25
Issue: 7
Pages: 451-461
•
•
•
•
•
Publication
26921108 | J:254662
First Author: Larson-Casey JL
Year: 2016
Journal: Immunity
Title: Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis.
Volume: 44
Issue: 3
Pages: 582-596
•
•
•
•
•
Publication
20816796 | J:166615
First Author: Chang Z
Year: 2010
Journal: Dev Biol
Title: Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation.
Volume: 347
Issue: 2
Pages: 384-91
•
•
•
•
•
Publication
25201081 | J:218454
First Author: Yun SJ
Year: 2014
Journal: Biochim Biophys Acta
Title: Akt1 isoform modulates phenotypic conversion of vascular smooth muscle cells.
Volume: 1842
Issue: 11
Pages: 2184-92
•
•
•
•
•
Publication
16227992 | J:102877
First Author: Chen J
Year: 2005
Journal: Nat Med
Title: Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.
Volume: 11
Issue: 11
Pages: 1188-96
•
•
•
•
•
Publication
24663486 | J:214152
First Author: Mukherjee A
Year: 2014
Journal: PLoS One
Title: Distinct actions of akt1 on skeletal architecture and function.
Volume: 9
Issue: 3
Pages: e93040
•
•
•
•
•
Publication
17562714 | J:124800
First Author: Somanath PR
Year: 2007
Journal: J Biol Chem
Title: Akt1 signaling regulates integrin activation, matrix recognition, and fibronectin assembly.
Volume: 282
Issue: 31
Pages: 22964-76
•
•
•
•
•
Publication
23904165 | J:205816
First Author: Liu G
Year: 2013
Journal: J Immunol
Title: Kinase AKT1 negatively controls neutrophil recruitment and function in mice.
Volume: 191
Issue: 5
Pages: 2680-90
•
•
•
•
•
Publication
22117619 | J:324970
First Author: Kunuthur SP
Year: 2012
Journal: J Cell Mol Med
Title: The Akt1 isoform is an essential mediator of ischaemic preconditioning.
Volume: 16
Issue: 8
Pages: 1739-49
•
•
•
•
•
Publication
30833219 | J:294695
 
First Author: Sanchez-Gurmaches J
Year: 2019
Journal: Mol Metab
Title: Brown fat organogenesis and maintenance requires AKT1 and AKT2.
Volume: 23
Pages: 60-74
•
•
•
•
•
Publication
19491266 | J:149659
First Author: Dillon RL
Year: 2009
Journal: Cancer Res
Title: Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression.
Volume: 69
Issue: 12
Pages: 5057-64
•
•
•
•
•
Publication
20363892 | J:160448
First Author: Beiser DG
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Akt1 genetic deficiency limits hypothermia cardioprotection following murine cardiac arrest.
Volume: 298
Issue: 6
Pages: H1761-8
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167236
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189759
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Akt1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167236
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189759
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Akt1
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167236
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189759
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Akt1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167236
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189759
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Akt1
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167236
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189759
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Akt1
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167236
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189759
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Akt1
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6167236
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189759
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Akt1
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
19622728 | J:152016
First Author: Di Lorenzo A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.
Volume: 106
Issue: 34
Pages: 14552-7
•
•
•
•
•
Publication
25136137 | J:216407
First Author: Lee MY
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.
Volume: 111
Issue: 35
Pages: 12865-70
•
•
•
•
•
Publication
22647600 | J:185519
First Author: Arranz A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization.
Volume: 109
Issue: 24
Pages: 9517-22
•
•
•
•
•
Publication
19699171 | J:151838
First Author: Androulidaki A
Year: 2009
Journal: Immunity
Title: The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs.
Volume: 31
Issue: 2
Pages: 220-31
•
•
•
•
•
Publication
18054314 | J:130443
First Author: Fernández-Hernando C
Year: 2007
Journal: Cell Metab
Title: Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease.
Volume: 6
Issue: 6
Pages: 446-57
•
•
•
•
•
Publication
24400145 | J:227956
First Author: Vandoorne K
Year: 2013
Journal: Physiol Rep
Title: Multimodal imaging reveals a role for Akt1 in fetal cardiac development.
Volume: 1
Issue: 6
Pages: e00143
•
•
•
•
•
Publication
22151747 | J:198105
First Author: Chen YC
Year: 2012
Journal: Genes Brain Behav
Title: Akt1 deficiency modulates reward learning and reward prediction error in mice.
Volume: 11
Issue: 2
Pages: 157-69
•
•
•
•
•
Publication
22064480 | J:183672
First Author: Mukherjee A
Year: 2012
Journal: Mol Cell Biol
Title: Selective signaling by Akt1 controls osteoblast differentiation and osteoblast-mediated osteoclast development.
Volume: 32
Issue: 2
Pages: 490-500
•
•
•
•
•
Publication
20354168 | J:160459
First Author: Juntilla MM
Year: 2010
Journal: Blood
Title: AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.
Volume: 115
Issue: 20
Pages: 4030-8
•
•
•
•
•
Publication
26654940 | J:302263
First Author: Franks SE
Year: 2016
Journal: Oncotarget
Title: Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis.
Volume: 7
Issue: 3
Pages: 3297-316
•
•
•
•
•
Publication
25868464 | J:248769
First Author: Rotllan N
Year: 2015
Journal: Circ Res
Title: Genetic Evidence Supports a Major Role for Akt1 in VSMCs During Atherogenesis.
Volume: 116
Issue: 11
Pages: 1744-52
•
•
•
•
•
Publication
17077150 | J:117100
First Author: Lai WS
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning.
Volume: 103
Issue: 45
Pages: 16906-11
•
•
•
•
•
Publication
23787999 | J:228616
First Author: Green BD
Year: 2013
Journal: Cell Death Differ
Title: Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations.
Volume: 20
Issue: 10
Pages: 1341-9
•
•
•
•
•
Publication
22037765 | J:182721
First Author: Wan M
Year: 2012
Journal: Mol Cell Biol
Title: Loss of Akt1 in mice increases energy expenditure and protects against diet-induced obesity.
Volume: 32
Issue: 1
Pages: 96-106
•
•
•
•
•
Publication
16778075 | J:109600
First Author: Chen ML
Year: 2006
Journal: Genes Dev
Title: The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice.
Volume: 20
Issue: 12
Pages: 1569-74
•
•
•
•
•
Publication
17141631 | J:129773
First Author: Boxer RB
Year: 2006
Journal: Cell Metab
Title: Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.
Volume: 4
Issue: 6
Pages: 475-90
•
•
•
•
•
Publication
25388284 | J:218209
First Author: Phung TL
Year: 2015
Journal: Cancer Res
Title: Akt1 and akt3 exert opposing roles in the regulation of vascular tumor growth.
Volume: 75
Issue: 1
Pages: 40-50
•
•
•
•
•
Publication
32931746 | J:297182
First Author: Chen X
Year: 2020
Journal: Mol Cell
Title: Cell-Autonomous versus Systemic Akt Isoform Deletions Uncovered New Roles for Akt1 and Akt2 in Breast Cancer.
Volume: 80
Issue: 1
Pages: 87-101.e5
•
•
•
•
•
Publication
30984553 | J:290242
First Author: Ha JM
Year: 2019
Journal: FEBS Open Bio
Title: Vascular leakage caused by loss of Akt1 is associated with impaired mural cell coverage.
Volume: 9
Issue: 4
Pages: 801-813
•
•
•
•
•
Publication
27615800 | J:293081
 
First Author: Chang CY
Year: 2016
Journal: Sci Rep
Title: Akting up in the GABA hypothesis of schizophrenia: Akt1 deficiency modulates GABAergic functions and hippocampus-dependent functions.
Volume: 6
Pages: 33095
•
•
•
•
•
Publication
33038070 | J:313524
First Author: Miyazaki M
Year: 2020
Journal: Physiol Rep
Title: Transient activation of mTORC1 signaling in skeletal muscle is independent of Akt1 regulation.
Volume: 8
Issue: 19
Pages: e14599
•
•
•
•
•
Publication
37984409 | J:358193
First Author: Na D
Year: 2023
Journal: Mol Syst Biol
Title: A multi-layered network model identifies Akt1 as a common modulator of neurodegeneration.
Volume: 19
Issue: 12
Pages: e11801
•
•
•
•
•
Publication
32179553 | J:293069
 
First Author: Peng Z
Year: 2020
Journal: Mol Cell Biol
Title: AKT1 Regulates Endoplasmic Reticulum Stress and Mediates the Adaptive Response of Pancreatic β Cells.
Volume: 40
Issue: 11
•
•
•
•
•
Publication
22930469 | J:190353
First Author: Pierau M
Year: 2012
Journal: Eur J Immunol
Title: Constitutive Akt1 signals attenuate B-cell receptor signaling and proliferation, but enhance B-cell migration and effector function.
Volume: 42
Issue: 12
Pages: 3381-93
•
•
•
•
•
Publication
29443546 | J:262191
First Author: Moriya N
Year: 2018
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Akt1 deficiency diminishes skeletal muscle hypertrophy by reducing satellite cell proliferation.
Volume: 314
Issue: 5
Pages: R741-R751
•
•
•
•
•
Publication
22904301 | J:189917
First Author: Gantner BN
Year: 2012
Journal: J Immunol
Title: The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin.
Volume: 189
Issue: 6
Pages: 3104-11
•
•
•
•
•
Publication
24933620 | J:219438
 
First Author: Ahmad F
Year: 2014
Journal: Free Radic Biol Med
Title: Critical cysteines in Akt1 regulate its activity and proteasomal degradation: implications for neurodegenerative diseases.
Volume: 74
Pages: 118-28
•
•
•
•
•
Publication
23300339 | J:255333
First Author: Yao Y
Year: 2013
Journal: Sci Signal
Title: BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation.
Volume: 6
Issue: 257
Pages: ra2
•
•
•
•
•
Publication
21915327 | J:177888
First Author: LaRocca J
Year: 2011
Journal: PLoS One
Title: Akt1 is essential for postnatal mammary gland development, function, and the expression of Btn1a1.
Volume: 6
Issue: 9
Pages: e24432
•
•
•
•
•
Publication
19270695 | J:158181
First Author: Gao D
Year: 2009
Journal: Nat Cell Biol
Title: Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction.
Volume: 11
Issue: 4
Pages: 397-408
•
•
•
•
•
Publication
31531867 | J:293787
First Author: Chen R
Year: 2020
Journal: J Pathol
Title: Akt1 signalling supports acinar proliferation and limits acinar-to-ductal metaplasia formation upon induction of acute pancreatitis.
Volume: 250
Issue: 1
Pages: 42-54
•
•
•
•
•
Publication
24742286 | J:317511
 
First Author: Wu Y
Year: 2014
Journal: BMC Cancer
Title: Activation of Akt1 accelerates carcinogen-induced tumorigenesis in mammary gland of virgin and post-lactating transgenic mice.
Volume: 14
Pages: 266
•
•
•
•
•
Publication
22562201 | J:184520
First Author: Kent LN
Year: 2012
Journal: Int J Dev Biol
Title: Akt1 and insulin-like growth factor 2 (Igf2) regulate placentation and fetal/postnatal development.
Volume: 56
Issue: 4
Pages: 255-61
•
•
•
•
•
Publication
25046438 | J:214225
First Author: Ma L
Year: 2014
Journal: Lab Invest
Title: Differential effects of Akt1 signaling on short- versus long-term consequences of myocardial infarction and reperfusion injury.
Volume: 94
Issue: 10
Pages: 1083-91
•
•
•
•
•
Publication
24955524 | J:217945
First Author: Kong KA
Year: 2014
Journal: Biochim Biophys Acta
Title: Akt1 mediates the posterior Hoxc gene expression through epigenetic modifications in mouse embryonic fibroblasts.
Volume: 1839
Issue: 9
Pages: 793-9
•
•
•
•
•
Publication
16982699 | J:114644
First Author: Héron-Milhavet L
Year: 2006
Journal: Mol Cell Biol
Title: Only Akt1 is required for proliferation, while Akt2 promotes cell cycle exit through p21 binding.
Volume: 26
Issue: 22
Pages: 8267-80
•
•
•
•
•
Publication
17609365 | J:123155
First Author: Juntilla MM
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.
Volume: 104
Issue: 29
Pages: 12105-10
•
•
•
•
•
Publication
25748236 | J:311968
First Author: Albury TM
Year: 2015
Journal: Neoplasia
Title: Constitutively active Akt1 cooperates with KRas(G12D) to accelerate in vivo pancreatic tumor onset and progression.
Volume: 17
Issue: 2
Pages: 175-82
•
•
•
•
•
Publication
18700973 | J:142118
First Author: Young CD
Year: 2008
Journal: Breast Cancer Res
Title: Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3.
Volume: 10
Issue: 4
Pages: R70
•
•
•
•
•
Publication
24106278 | J:204981
First Author: Abdalla M
Year: 2013
Journal: J Biol Chem
Title: Akt1 mediates α-smooth muscle actin expression and myofibroblast differentiation via myocardin and serum response factor.
Volume: 288
Issue: 46
Pages: 33483-93
•
•
•
•
•
Publication
25843685 | J:230544
First Author: Goc A
Year: 2015
Journal: Biochim Biophys Acta
Title: p70 S6-kinase mediates the cooperation between Akt1 and Mek1 pathways in fibroblast-mediated extracellular matrix remodeling.
Volume: 1853
Issue: 7
Pages: 1626-35
•
•
•
•
•
Publication
33030203 | J:298839
First Author: Lindhurst MJ
Year: 2020
Journal: Hum Mol Genet
Title: Ubiquitous expression of Akt1 p.(E17K) results in vascular defects and embryonic lethality in mice.
Volume: 29
Issue: 20
Pages: 3350-3360
•
•
•
•
•
Publication
17012749 | J:117620
First Author: Zhou GL
Year: 2006
Journal: J Biol Chem
Title: Opposing roles for Akt1 and Akt2 in Rac/Pak signaling and cell migration.
Volume: 281
Issue: 47
Pages: 36443-53
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom