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Search results 1 to 100 out of 358 for Aldh2

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0.057s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zhang Q
Year: 2017
Journal: Biochem Biophys Res Commun
Title: ALDH2 restores exhaustive exercise-induced mitochondrial dysfunction in skeletal muscle.
Volume: 485
Issue: 4
Pages: 753-760
Publication
First Author: Zhao Y
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: ALDH2 (Aldehyde Dehydrogenase 2) Protects Against Hypoxia-Induced Pulmonary Hypertension.
Volume: 39
Issue: 11
Pages: 2303-2319
Publication
First Author: Chang YC
Year: 2023
Journal: Nat Commun
Title: A common East-Asian ALDH2 mutation causes metabolic disorders and the therapeutic effect of ALDH2 activators.
Volume: 14
Issue: 1
Pages: 5971
Publication  
First Author: Amanuma Y
Year: 2015
Journal: Sci Rep
Title: Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.
Volume: 5
Pages: 14142
Publication
First Author: Li K
Year: 2019
Journal: Neoplasia
Title: ALDH2 Repression Promotes Lung Tumor Progression via Accumulated Acetaldehyde and DNA Damage.
Volume: 21
Issue: 6
Pages: 602-614
Publication  
First Author: Kobayashi H
Year: 2021
Journal: Bone
Title: ALDH2 mutation promotes skeletal muscle atrophy in mice via accumulation of oxidative stress.
Volume: 142
Pages: 115739
Publication
First Author: Jin S
Year: 2021
Journal: Nat Metab
Title: Brain ethanol metabolism by astrocytic ALDH2 drives the behavioural effects of ethanol intoxication.
Volume: 3
Issue: 3
Pages: 337-351
Publication
First Author: Guo H
Year: 2023
Journal: Sci Transl Med
Title: SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant.
Volume: 15
Issue: 680
Pages: eabp9952
Publication
First Author: Pang J
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Mitochondrial ALDH2 protects against lipopolysaccharide-induced myocardial contractile dysfunction by suppression of ER stress and autophagy.
Volume: 1865
Issue: 6
Pages: 1627-1641
Publication  
First Author: Kim DK
Year: 2019
Journal: Int J Mol Sci
Title: Aldh2 Attenuates Stem Cell Factor/Kit-Dependent Signaling and Activation in Mast Cells.
Volume: 20
Issue: 24
Publication
First Author: Hoshi H
Year: 2012
Journal: J Bone Miner Res
Title: Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis.
Volume: 27
Issue: 9
Pages: 2015-23
Publication
First Author: Zhai X
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Protective effect of ALDH2 against cyclophosphamide-induced acute hepatotoxicity via attenuating oxidative stress and reactive aldehydes.
Volume: 499
Issue: 1
Pages: 93-98
Publication
First Author: Chaudhry KK
Year: 2015
Journal: Alcohol Clin Exp Res
Title: ALDH2 Deficiency Promotes Ethanol-Induced Gut Barrier Dysfunction and Fatty Liver in Mice.
Volume: 39
Issue: 8
Pages: 1465-75
Publication  
First Author: D'Souza Y
Year: 2015
Journal: Mol Brain
Title: Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease.
Volume: 8
Pages: 27
Publication  
First Author: Xia G
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Loss of ALDH2 aggravates mitochondrial biogenesis disorder in cardiac myocytes induced by TAC.
Volume: 639
Pages: 189-196
Publication
First Author: Seo W
Year: 2019
Journal: J Hepatol
Title: ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles.
Volume: 71
Issue: 5
Pages: 1000-1011
Publication  
First Author: Ji E
Year: 2020
Journal: Biomed Res Int
Title: Molecular Mechanism of HSF1-Upregulated ALDH2 by PKC in Ameliorating Pressure Overload-Induced Heart Failure in Mice.
Volume: 2020
Pages: 3481623
Publication
First Author: Wei S
Year: 2019
Journal: Biochem Biophys Res Commun
Title: ALDH2 deficiency inhibits Ox-LDL induced foam cell formation via suppressing CD36 expression.
Volume: 512
Issue: 1
Pages: 41-48
Publication
First Author: Long P
Year: 2020
Journal: Aging (Albany NY)
Title: ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum.
Volume: 13
Issue: 2
Pages: 2750-2767
Publication  
First Author: Oyama T
Year: 2005
Journal: Front Biosci
Title: Tissue-distribution of aldehyde dehydrogenase 2 and effects of the ALDH2 gene-disruption on the expression of enzymes involved in alcohol metabolism.
Volume: 10
Pages: 951-60
Publication
First Author: Hirohashi K
Year: 2020
Journal: Carcinogenesis
Title: Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2 (Glu504Lys) knock-in mice.
Volume: 41
Issue: 2
Pages: 194-202
GXD Expression    
Probe: MGI:6167260
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189765
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Aldh2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6167260
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189765
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Aldh2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6167260
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189765
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Aldh2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6167260
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189765
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Aldh2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6167260
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189765
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Aldh2
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6167260
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189765
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Aldh2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6167260
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189765
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Aldh2
Detected: true
Specimen Num: 5
Publication
First Author: Hu YF
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: ALDH2 deficiency induces atrial fibrillation through dysregulated cardiac sodium channel and mitochondrial bioenergetics: A multi-omics analysis.
Volume: 1867
Issue: 5
Pages: 166088
Publication
First Author: Zhang J
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: Macrophage ALDH2 (Aldehyde Dehydrogenase 2) Stabilizing Rac2 Is Required for Efferocytosis Internalization and Reduction of Atherosclerosis Development.
Volume: 42
Issue: 6
Pages: 700-716
Publication
First Author: Kitagawa K
Year: 2000
Journal: FEBS Lett
Title: Aldehyde dehydrogenase (ALDH) 2 associates with oxidation of methoxyacetaldehyde; in vitro analysis with liver subcellular fraction derived from human and Aldh2 gene targeting mouse.
Volume: 476
Issue: 3
Pages: 306-11
Publication  
First Author: Zhang Y
Year: 2023
Journal: Front Pharmacol
Title: ALDH2 attenuates myocardial pyroptosis through breaking down Mitochondrion-NLRP3 inflammasome pathway in septic shock.
Volume: 14
Pages: 1125866
Publication
First Author: Wang S
Year: 2018
Journal: Int J Obes (Lond)
Title: ALDH2 protects against high fat diet-induced obesity cardiomyopathy and defective autophagy: role of CaM kinase II, histone H3K9 methyltransferase SUV39H, Sirt1, and PGC-1α deacetylation.
Volume: 42
Issue: 5
Pages: 1073-1087
Publication
First Author: Chen CH
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Pharmacological recruitment of aldehyde dehydrogenase 3A1 (ALDH3A1) to assist ALDH2 in acetaldehyde and ethanol metabolism in vivo.
Volume: 112
Issue: 10
Pages: 3074-9
Publication  
First Author: Matsumoto A
Year: 2016
Journal: Alcohol
Title: Heme oxygenase 1 protects ethanol-administered liver tissue in Aldh2 knockout mice.
Volume: 52
Pages: 49-54
Publication
First Author: Sun JK
Year: 2023
Journal: Aging Cell
Title: Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons.
Volume: 22
Issue: 2
Pages: e13772
Publication  
First Author: Zhong S
Year: 2021
Journal: Redox Biol
Title: Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver.
Volume: 41
Pages: 101919
Allele
Name: transgene insertion 1, Bradford Hill
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Jin S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis.
Volume: 112
Issue: 29
Pages: 9088-93
Publication
First Author: Kasai A
Year: 2022
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Aldehyde dehydrogenase 2 deficiency promotes skeletal muscle atrophy in aged mice.
Volume: 322
Issue: 6
Pages: R511-R525
Publication
First Author: Nagayoshi H
Year: 2009
Journal: Mutat Res
Title: Increased formation of gastric N(2)-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase-2 knockout mice treated with ethanol.
Volume: 673
Issue: 1
Pages: 74-7
Publication
First Author: Langevin F
Year: 2011
Journal: Nature
Title: Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice.
Volume: 475
Issue: 7354
Pages: 53-8
Publication
First Author: Dingler FA
Year: 2020
Journal: Mol Cell
Title: Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans.
Volume: 80
Issue: 6
Pages: 996-1012.e9
Publication
First Author: Pan G
Year: 2018
Journal: PLoS One
Title: Type-2 diabetic aldehyde dehydrogenase 2 mutant mice (ALDH 2*2) exhibiting heart failure with preserved ejection fraction phenotype can be determined by exercise stress echocardiography.
Volume: 13
Issue: 4
Pages: e0195796
Publication
First Author: Zambelli VO
Year: 2014
Journal: Sci Transl Med
Title: Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain.
Volume: 6
Issue: 251
Pages: 251ra118
Publication
First Author: Beretta M
Year: 2012
Journal: Circ Res
Title: Vascular bioactivation of nitroglycerin is catalyzed by cytosolic aldehyde dehydrogenase-2.
Volume: 110
Issue: 3
Pages: 385-93
Publication
First Author: Fernandez E
Year: 2006
Journal: Alcohol Clin Exp Res
Title: Monoamine metabolism and behavioral responses to ethanol in mitochondrial aldehyde dehydrogenase knockout mice.
Volume: 30
Issue: 10
Pages: 1650-8
Publication
First Author: Kim YD
Year: 2005
Journal: Arch Toxicol
Title: Expression levels of hepatic cytochrome P450 enzymes in Aldh2-deficient mice following ethanol exposure: a pilot study.
Volume: 79
Issue: 4
Pages: 192-5
Publication
First Author: Isse T
Year: 2005
Journal: J Toxicol Sci
Title: Aldehyde dehydrogenase 2 activity affects symptoms produced by an intraperitoneal acetaldehyde injection, but not acetaldehyde lethality.
Volume: 30
Issue: 4
Pages: 315-28
Publication
First Author: Okuma KF
Year: 2017
Journal: Calcif Tissue Int
Title: Disruption of the Aldehyde Dehydrogenase 2 Gene Results in No Increase in Trabecular Bone Mass Due to Skeletal Loading in Association with Impaired Cell Cycle Regulation Through p21 Expression in the Bone Marrow Cells of Mice.
Volume: 101
Issue: 3
Pages: 328-340
Publication  
First Author: Li X
Year: 2019
Journal: J Mol Cell Cardiol
Title: Acetaldehyde dehydrogenase 2 deficiency exacerbates cardiac fibrosis by promoting mobilization and homing of bone marrow fibroblast progenitor cells.
Volume: 137
Pages: 107-118
Publication
First Author: Matsumoto A
Year: 2007
Journal: Alcohol
Title: Lack of aldehyde dehydrogenase ameliorates oxidative stress induced by single-dose ethanol administration in mouse liver.
Volume: 41
Issue: 1
Pages: 57-9
Publication
First Author: Ma H
Year: 2011
Journal: Eur Heart J
Title: Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde.
Volume: 32
Issue: 8
Pages: 1025-38
Publication  
First Author: Sun X
Year: 2017
Journal: Redox Biol
Title: Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia.
Volume: 13
Pages: 196-206
Publication
First Author: Xia G
Year: 2016
Journal: Biochim Biophys Acta
Title: Aldehyde dehydrogenase 2 deficiency blunts compensatory cardiac hypertrophy through modulating Akt phosphorylation early after transverse aorta constriction in mice.
Volume: 1862
Issue: 9
Pages: 1587-93
Publication
First Author: Isse T
Year: 2002
Journal: Pharmacogenetics
Title: Diminished alcohol preference in transgenic mice lacking aldehyde dehydrogenase activity.
Volume: 12
Issue: 8
Pages: 621-6
Publication  
First Author: Xu T
Year: 2021
Journal: JCI Insight
Title: Aldehyde dehydrogenase 2 protects against acute kidney injury by regulating autophagy via the Beclin-1 pathway.
Volume: 6
Issue: 15
Publication  
First Author: Liu W
Year: 2018
Journal: J Mol Cell Cardiol
Title: Aldehyde dehydrogenase 2 activation ameliorates cyclophosphamide-induced acute cardiotoxicity via detoxification of toxic aldehydes and suppression of cardiac cell death.
Volume: 121
Pages: 134-144
Publication
First Author: Lee AS
Year: 2023
Journal: Commun Biol
Title: A Common East Asian aldehyde dehydrogenase 2*2 variant promotes ventricular arrhythmia with chronic light-to-moderate alcohol use in mice.
Volume: 6
Issue: 1
Pages: 610
Publication
First Author: Li SY
Year: 2009
Journal: J Mol Cell Cardiol
Title: Aldehyde dehydrogenase-2 (ALDH2) ameliorates chronic alcohol ingestion-induced myocardial insulin resistance and endoplasmic reticulum stress.
Volume: 47
Issue: 2
Pages: 247-55
Publication
First Author: Zhang B
Year: 2013
Journal: Biochim Biophys Acta
Title: Mitochondrial aldehyde dehydrogenase obliterates endoplasmic reticulum stress-induced cardiac contractile dysfunction via correction of autophagy.
Volume: 1832
Issue: 4
Pages: 574-84
Publication
First Author: Van Wassenhove LD
Year: 2016
Journal: Mol Genet Metab
Title: Aldehyde dehydrogenase 2 in aplastic anemia, Fanconi anemia and hematopoietic stem cells.
Volume: 119
Issue: 1-2
Pages: 28-36
Publication
First Author: Roy B
Year: 2022
Journal: FASEB J
Title: Aldehyde dehydrogenase 2 augments adiponectin signaling in coronary angiogenesis in HFpEF associated with diabetes.
Volume: 36
Issue: 8
Pages: e22440
Publication
First Author: Li J
Year: 2023
Journal: Cell Death Dis
Title: Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury.
Volume: 14
Issue: 1
Pages: 45
Publication
First Author: Ohsawa I
Year: 2008
Journal: J Neurosci
Title: Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity.
Volume: 28
Issue: 24
Pages: 6239-49
Publication
First Author: Griesberger M
Year: 2011
Journal: Mol Pharmacol
Title: Bioactivation of pentaerythrityl tetranitrate by mitochondrial aldehyde dehydrogenase.
Volume: 79
Issue: 3
Pages: 541-8
Publication
First Author: Weng Z
Year: 2014
Journal: Arch Toxicol
Title: Assessment of the reproductive toxicity of inhalation exposure to ethyl tertiary butyl ether in male mice with normal, low active and inactive ALDH2.
Volume: 88
Issue: 4
Pages: 1007-21
Publication
First Author: Isse T
Year: 2005
Journal: J Toxicol Sci
Title: Paired acute inhalation test reveals that acetaldehyde toxicity is higher in aldehyde dehydrogenase 2 knockout mice than in wild-type mice.
Volume: 30
Issue: 4
Pages: 329-37
Publication  
First Author: Sun A
Year: 2014
Journal: J Mol Cell Cardiol
Title: Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy.
Volume: 71
Pages: 92-104
Publication  
First Author: Liao J
Year: 2012
Journal: Mol Med
Title: Aldehyde dehydrogenase-2 deficiency aggravates cardiac dysfunction elicited by endoplasmic reticulum stress induction.
Volume: 18
Pages: 785-93
Publication  
First Author: Ma LL
Year: 2021
Journal: Redox Biol
Title: Hypertrophic preconditioning cardioprotection after myocardial ischaemia/reperfusion injury involves ALDH2-dependent metabolism modulation.
Volume: 43
Pages: 101960
Publication  
First Author: Tajima T
Year: 2018
Journal: Bone
Title: Cortical bone loss due to skeletal unloading in aldehyde dehydrogenase 2 gene knockout mice is associated with decreased PTH receptor expression in osteocytes.
Volume: 110
Pages: 254-266
Publication
First Author: Fan F
Year: 2014
Journal: Acta Pharmacol Sin
Title: Impact of chronic low to moderate alcohol consumption on blood lipid and heart energy profile in acetaldehyde dehydrogenase 2-deficient mice.
Volume: 35
Issue: 8
Pages: 1015-22
Publication
First Author: Ge W
Year: 2011
Journal: Free Radic Biol Med
Title: AMP-dependent kinase and autophagic flux are involved in aldehyde dehydrogenase-2-induced protection against cardiac toxicity of ethanol.
Volume: 51
Issue: 9
Pages: 1736-48
Publication
First Author: Wang M
Year: 2023
Journal: Mol Cell
Title: Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner.
Volume: 83
Issue: 14
Pages: 2417-2433.e7
Publication
First Author: Shen C
Year: 2015
Journal: Biochim Biophys Acta
Title: Acetaldehyde dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway.
Volume: 1852
Issue: 2
Pages: 310-8
Publication
First Author: Marino A
Year: 2017
Journal: J Pharmacol Exp Ther
Title: S1P receptor 1-Mediated Anti-Renin-Angiotensin System Cardioprotection: Pivotal Role of Mast Cell Aldehyde Dehydrogenase Type 2.
Volume: 362
Issue: 2
Pages: 230-242
Publication  
First Author: Ai L
Year: 2019
Journal: Commun Biol
Title: Endogenous formaldehyde is a memory-related molecule in mice and humans.
Volume: 2
Pages: 446
Publication
First Author: Matsumoto A
Year: 2007
Journal: Alcohol
Title: Single-dose ethanol administration downregulates expression of cytochrome p450 2E1 mRNA in aldehyde dehydrogenase 2 knockout mice.
Volume: 41
Issue: 8
Pages: 587-9
Publication
First Author: Ma H
Year: 2010
Journal: J Mol Cell Cardiol
Title: Aldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression: role of protein phosphatases.
Volume: 49
Issue: 2
Pages: 322-9
Publication  
First Author: Kosugi K
Year: 2020
Journal: Bone
Title: Disruption of the aldehyde dehydrogenase 2 gene increases the bone anabolic response to intermittent PTH treatment in an ovariectomized mouse model.
Volume: 136
Pages: 115370
Publication
First Author: Kim J
Year: 2017
Journal: J Biomed Sci
Title: Aldehyde dehydrogenase 2*2 knock-in mice show increased reactive oxygen species production in response to cisplatin treatment.
Volume: 24
Issue: 1
Pages: 33
Publication
First Author: Kuroda A
Year: 2017
Journal: Respir Res
Title: Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung.
Volume: 18
Issue: 1
Pages: 69
Publication
First Author: Chang C
Year: 1994
Journal: Gene
Title: Cloning and characterization of the gene encoding mouse mitochondrial aldehyde dehydrogenase.
Volume: 148
Issue: 2
Pages: 331-6
Publication
First Author: Budas GR
Year: 2010
Journal: J Mol Cell Cardiol
Title: Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice.
Volume: 48
Issue: 4
Pages: 757-64
Publication  
First Author: Zhang Y
Year: 2014
Journal: Free Radic Biol Med
Title: Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function.
Volume: 71
Pages: 208-20
Publication
First Author: Sun A
Year: 2014
Journal: J Am Heart Assoc
Title: Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice.
Volume: 3
Issue: 5
Pages: e000779
Publication
First Author: Wakabayashi Y
Year: 2020
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle.
Volume: 318
Issue: 4
Pages: R677-R690
Publication
First Author: Endo J
Year: 2009
Journal: Circ Res
Title: Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart.
Volume: 105
Issue: 11
Pages: 1118-27
Publication
First Author: Ge W
Year: 2016
Journal: Biochim Biophys Acta
Title: Mitochondrial aldehyde dehydrogenase protects against doxorubicin cardiotoxicity through a transient receptor potential channel vanilloid 1-mediated mechanism.
Volume: 1862
Issue: 4
Pages: 622-634
Publication
First Author: Wu B
Year: 2016
Journal: Oncotarget
Title: Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1.
Volume: 7
Issue: 3
Pages: 2175-88