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Search results 1 to 100 out of 782 for Alpl

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0.043s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Foster BL
Year: 2017
Journal: J Dent Res
Title: Conditional Alpl Ablation Phenocopies Dental Defects of Hypophosphatasia.
Volume: 96
Issue: 1
Pages: 81-91
Publication  
First Author: Kramer K
Year: 2021
Journal: Bone
Title: Dental defects in the primary dentition associated with hypophosphatasia from biallelic ALPL mutations.
Volume: 143
Pages: 115732
Publication
First Author: Zhang L
Year: 2021
Journal: Stem Cell Res Ther
Title: GSK3β rephosphorylation rescues ALPL deficiency-induced impairment of odontoblastic differentiation of DPSCs.
Volume: 12
Issue: 1
Pages: 225
Publication
First Author: Nielson CM
Year: 2012
Journal: J Bone Miner Res
Title: Rare coding variants in ALPL are associated with low serum alkaline phosphatase and low bone mineral density.
Volume: 27
Issue: 1
Pages: 93-103
Publication
First Author: Cruz T
Year: 2017
Journal: J Neurochem
Title: Identification of altered brain metabolites associated with TNAP activity in a mouse model of hypophosphatasia using untargeted NMR-based metabolomics analysis.
Volume: 140
Issue: 6
Pages: 919-940
Publication  
First Author: Bessueille L
Year: 2020
Journal: Bone
Title: Tissue-nonspecific alkaline phosphatase is an anti-inflammatory nucleotidase.
Volume: 133
Pages: 115262
Publication  
First Author: Gasque KC
Year: 2015
Journal: Bone
Title: Improvement of the skeletal and dental hypophosphatasia phenotype in Alpl-/- mice by administration of soluble (non-targeted) chimeric alkaline phosphatase.
Volume: 72
Pages: 137-47
Publication
First Author: McKee MD
Year: 2013
Journal: J Dent Res
Title: Compounded PHOSPHO1/ALPL deficiencies reduce dentin mineralization.
Volume: 92
Issue: 8
Pages: 721-7
Publication
First Author: Nakamura T
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Tissue-nonspecific alkaline phosphatase promotes the osteogenic differentiation of osteoprogenitor cells.
Volume: 524
Issue: 3
Pages: 702-709
Publication
First Author: Sebastián-Serrano Á
Year: 2016
Journal: Hum Mol Genet
Title: Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation.
Volume: 25
Issue: 19
Pages: 4143-4156
Publication
First Author: Halling Linder C
Year: 2013
Journal: Bone
Title: Isozyme profile and tissue-origin of alkaline phosphatases in mouse serum.
Volume: 53
Issue: 2
Pages: 399-408
Publication
First Author: Yoshizaki K
Year: 2017
Journal: J Biol Chem
Title: Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene.
Volume: 292
Issue: 33
Pages: 13531-13540
Publication  
First Author: Flowers S
Year: 2014
Journal: Bone
Title: p107-Dependent recruitment of SWI/SNF to the alkaline phosphatase promoter during osteoblast differentiation.
Volume: 69
Pages: 47-54
Publication
First Author: Foster BL
Year: 2015
Journal: J Dent Res
Title: Periodontal Defects in the A116T Knock-in Murine Model of Odontohypophosphatasia.
Volume: 94
Issue: 5
Pages: 706-14
Publication
First Author: Street SE
Year: 2013
Journal: J Neurosci
Title: Tissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord.
Volume: 33
Issue: 27
Pages: 11314-22
Publication  
First Author: Chu EY
Year: 2020
Journal: Bone
Title: Genetic and pharmacologic modulation of cementogenesis via pyrophosphate regulators.
Volume: 136
Pages: 115329
Publication  
First Author: Lewin HA
Year: 1994
Journal: Anim Genet
Title: The bovine B and C blood group systems are not likely to be the orthologues of human RH: an interesting twist in the comparative map.
Volume: 25 Suppl 1
Pages: 13-8
Publication
First Author: Lu X
Year: 2017
Journal: PLoS One
Title: ClC-3 chloride channel mediates the role of parathyroid hormone [1-34] on osteogenic differentiation of osteoblasts.
Volume: 12
Issue: 4
Pages: e0176196
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Terao M
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: Cloning and characterization of a cDNA coding for mouse placental alkaline phosphatase.
Volume: 84
Issue: 20
Pages: 7051-5
Publication
First Author: Brown NA
Year: 1990
Journal: J Biol Chem
Title: Induction of alkaline phosphatase in mouse L cells by overexpression of the catalytic subunit of cAMP-dependent protein kinase.
Volume: 265
Issue: 22
Pages: 13181-9
Publication
First Author: MacGregor GR
Year: 1995
Journal: Development
Title: Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryogenesis but is not required for migration of primordial germ cells.
Volume: 121
Issue: 5
Pages: 1487-96
Publication
First Author: Waymire KG
Year: 1995
Journal: Nat Genet
Title: Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6.
Volume: 11
Issue: 1
Pages: 45-51
Publication
First Author: Fedde KN
Year: 1999
Journal: J Bone Miner Res
Title: Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia.
Volume: 14
Issue: 12
Pages: 2015-26
Publication
First Author: Wennberg C
Year: 2000
Journal: J Bone Miner Res
Title: Functional characterization of osteoblasts and osteoclasts from alkaline phosphatase knockout mice.
Volume: 15
Issue: 10
Pages: 1879-88
Publication
First Author: Narisawa S
Year: 2001
Journal: J Pathol
Title: Abnormal vitamin B6 metabolism in alkaline phosphatase knock-out mice causes multiple abnormalities, but not the impaired bone mineralization.
Volume: 193
Issue: 1
Pages: 125-33
Publication
First Author: Anderson HC
Year: 2004
Journal: Am J Pathol
Title: Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient mice.
Volume: 164
Issue: 3
Pages: 841-7
Publication
First Author: Pinkerton AB
Year: 2018
Journal: Bioorg Med Chem Lett
Title: Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Volume: 28
Issue: 1
Pages: 31-34
Publication
First Author: Sun Y
Year: 2021
Journal: Nature
Title: Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine.
Volume: 593
Issue: 7860
Pages: 580-585
Publication
First Author: Hahnel AC
Year: 1990
Journal: Clin Chim Acta
Title: Cloning and characterization of a cDNA encoding alkaline phosphatase in mouse embryonal carcinoma cells.
Volume: 186
Issue: 2
Pages: 171-4
Publication
First Author: Hough TA
Year: 2007
Journal: J Bone Miner Res
Title: Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2.
Volume: 22
Issue: 9
Pages: 1397-407
Publication
First Author: Lomelí H
Year: 2000
Journal: Genesis
Title: Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells.
Volume: 26
Issue: 2
Pages: 116-7
Publication
First Author: Quah BJ
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Bystander B cells rapidly acquire antigen receptors from activated B cells by membrane transfer.
Volume: 105
Issue: 11
Pages: 4259-64
Publication
First Author: Schnabel D
Year: 2005
Journal: Dev Dyn
Title: Ectopic expression of KitD814Y in spermatids of transgenic mice, interferes with sperm morphogenesis.
Volume: 233
Issue: 1
Pages: 29-40
Publication
First Author: Beertsen W
Year: 1999
Journal: J Dent Res
Title: Root development in mice lacking functional tissue non-specific alkaline phosphatase gene: inhibition of acellular cementum formation.
Volume: 78
Issue: 6
Pages: 1221-9
Publication
First Author: Tesch W
Year: 2003
Journal: J Bone Miner Res
Title: Orientation of mineral crystallites and mineral density during skeletal development in mice deficient in tissue nonspecific alkaline phosphatase.
Volume: 18
Issue: 1
Pages: 117-25
Publication  
First Author: Pendleton EG
Year: 2023
Journal: Int J Mol Sci
Title: Compromised Muscle Properties in a Severe Hypophosphatasia Murine Model.
Volume: 24
Issue: 21
Publication
First Author: Hernández-Chirlaque C
Year: 2017
Journal: J Crohns Colitis
Title: Tissue Non-specific Alkaline Phosphatase Expression is Needed for the Full Stimulation of T Cells and T Cell-Dependent Colitis.
Volume: 11
Issue: 7
Pages: 857-870
Publication
First Author: Gámez-Belmonte R
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Experimental acute pancreatitis is enhanced in mice with tissue nonspecific alkaline phoshatase haplodeficiency due to modulation of neutrophils and acinar cells.
Volume: 1864
Issue: 11
Pages: 3769-3779
Publication  
First Author: Nam HK
Year: 2017
Journal: Front Physiol
Title: Tissue Nonspecific Alkaline Phosphatase (TNAP) Regulates Cranial Base Growth and Synchondrosis Maturation.
Volume: 8
Pages: 161
Publication
First Author: Yamamoto S
Year: 2011
Journal: J Bone Miner Res
Title: Prolonged survival and phenotypic correction of Akp2(-/-) hypophosphatasia mice by lentiviral gene therapy.
Volume: 26
Issue: 1
Pages: 135-42
Publication
First Author: Durussel J
Year: 2016
Journal: Dev Dyn
Title: Bone mineralization-dependent craniosynostosis and craniofacial shape abnormalities in the mouse model of infantile hypophosphatasia.
Volume: 245
Issue: 2
Pages: 175-82
Publication  
First Author: Liu J
Year: 2015
Journal: Bone
Title: Enzyme replacement for craniofacial skeletal defects and craniosynostosis in murine hypophosphatasia.
Volume: 78
Pages: 203-11
Publication  
First Author: Liu J
Year: 2014
Journal: Bone
Title: Tissue-nonspecific alkaline phosphatase deficiency causes abnormal craniofacial bone development in the Alpl(-/-) mouse model of infantile hypophosphatasia.
Volume: 67
Pages: 81-94
Publication
First Author: Kermer V
Year: 2010
Journal: Neurosci Lett
Title: Knockdown of tissue nonspecific alkaline phosphatase impairs neural stem cell proliferation and differentiation.
Volume: 485
Issue: 3
Pages: 208-11
Publication
First Author: Tada N
Year: 1984
Journal: Immunogenetics
Title: A new lymphocyte surface antigen (Ly-m31) controlled by a gene closely linked to the Akp-2 locus on mouse chromosome 4.
Volume: 20
Issue: 5
Pages: 589-92
Publication
First Author: Terao M
Year: 1988
Journal: Somat Cell Mol Genet
Title: Mapping of gene encoding mouse placental alkaline phosphatase to chromosome 4.
Volume: 14
Issue: 2
Pages: 211-5
Publication
First Author: Terao M
Year: 1990
Journal: Biochem J
Title: Isolation and characterization of the mouse liver/bone/kidney-type alkaline phosphatase gene.
Volume: 268
Issue: 3
Pages: 641-8
Publication
First Author: Studer M
Year: 1991
Journal: Biochem Biophys Res Commun
Title: Characterization of a second promoter for the mouse liver/bone/kidney-type alkaline phosphatase gene: cell and tissue specific expression.
Volume: 179
Issue: 3
Pages: 1352-60
Publication
First Author: Henthorn PS
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia.
Volume: 89
Issue: 20
Pages: 9924-8
Publication  
First Author: Giannì M
Year: 1993
Journal: Biochem J
Title: Retinoic acid and cyclic AMP synergistically induce the expression of liver/bone/kidney-type alkaline phosphatase gene in L929 fibroblastic cells.
Volume: 296 ( Pt 1)
Pages: 67-77
Publication
First Author: Escalante-Alcalde D
Year: 1996
Journal: Mech Dev
Title: Retinoic acid and methylation cis-regulatory elements control the mouse tissue non-specific alkaline phosphatase gene expression.
Volume: 57
Issue: 1
Pages: 21-32
Publication
First Author: Nakano Y
Year: 2004
Journal: Bone
Title: Site-specific localization of two distinct phosphatases along the osteoblast plasma membrane: tissue non-specific alkaline phosphatase and plasma membrane calcium ATPase.
Volume: 35
Issue: 5
Pages: 1077-85
Publication
First Author: Yonezawa T
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Harmine promotes osteoblast differentiation through bone morphogenetic protein signaling.
Volume: 409
Issue: 2
Pages: 260-5
Publication  
First Author: Zhang Z
Year: 2021
Journal: Int J Mol Sci
Title: Tissue Nonspecific Alkaline Phosphatase Function in Bone and Muscle Progenitor Cells: Control of Mitochondrial Respiration and ATP Production.
Volume: 22
Issue: 3
Publication
First Author: Brun LR
Year: 2018
Journal: J Bone Miner Metab
Title: Increased calcium uptake and improved trabecular bone properties in intestinal alkaline phosphatase knockout mice.
Volume: 36
Issue: 6
Pages: 661-667
Publication
First Author: Hanics J
Year: 2012
Journal: Cell Tissue Res
Title: Ablation of TNAP function compromises myelination and synaptogenesis in the mouse brain.
Volume: 349
Issue: 2
Pages: 459-71
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610712
Stage: TS12
Assay Id: MGI:1329165
Age: embryonic day 8.5
Image: 1
Specimen Label: 8.5a
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:1329165
Age: embryonic day 8.5
Image: 1
Specimen Label: 8.5w
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3291017
Stage: TS17
Assay Id: MGI:1329165
Age: embryonic day 10.5
Image: 1
Specimen Label: 10.5d
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:1329165
Age: embryonic day 10.5
Image: 1
Specimen Label: 10.5w
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3669919
Stage: TS19
Assay Id: MGI:1329165
Age: embryonic day 11.5
Image: 1
Specimen Label: 11.5gc
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:1329165
Age: embryonic day 11.5
Image: 1
Specimen Label: 11.5g
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:1329165
Age: embryonic day 11.5
Image: 1
Specimen Label: 11.5g
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:1329165
Age: embryonic day 11.5
Image: 1
Specimen Label: 11.5w
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3669920
Stage: TS20
Assay Id: MGI:1329165
Age: embryonic day 12.5
Image: 1
Specimen Label: 12.5gc
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738320
Stage: TS20
Assay Id: MGI:1329165
Age: embryonic day 12.5
Image: 1
Specimen Label: 12.5g
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1738320
Stage: TS20
Assay Id: MGI:1329165
Age: embryonic day 12.5
Image: 1
Specimen Label: 12.5g
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1328580
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1329165
Age: embryonic day 12.5
Image: 1
Specimen Label: 12.5w
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:1328581
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610712
Stage: TS12
Assay Id: MGI:1329172
Age: embryonic day 8.5
Image: 1
Specimen Label: 8.5a
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:1328581
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603912
Stage: TS12
Assay Id: MGI:1329172
Age: embryonic day 8.5
Image: 1
Specimen Label: 8.5w
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:1328581
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3291017
Stage: TS17
Assay Id: MGI:1329172
Age: embryonic day 10.5
Image: 1
Specimen Label: 10.5d
Detected: false
Specimen Num: 6