Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Xia Y |
Year: |
2016 |
Journal: |
Matrix Biol |
Title: |
Truncated amelogenin and LRAP transgenes improve Amelx null mouse enamel. |
Volume: |
52-54 |
|
Pages: |
198-206 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coxon TL |
Year: |
2012 |
Journal: |
Cells Tissues Organs |
Title: |
Phenotype-genotype correlations in mouse models of amelogenesis imperfecta caused by Amelx and Enam mutations. |
Volume: |
196 |
Issue: |
5 |
Pages: |
420-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barron MJ |
Year: |
2010 |
Journal: |
Hum Mol Genet |
Title: |
A mutation in the mouse Amelx tri-tyrosyl domain results in impaired secretion of amelogenin and phenocopies human X-linked amelogenesis imperfecta. |
Volume: |
19 |
Issue: |
7 |
Pages: |
1230-47 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
219
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Stifler CA |
Year: |
2022 |
Journal: |
J Struct Biol |
Title: |
Loss of biological control of enamel mineralization in amelogenin-phosphorylation-deficient mice. |
Volume: |
214 |
Issue: |
2 |
Pages: |
107844 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gibson CW |
Year: |
2007 |
Journal: |
J Dent Res |
Title: |
Transgenic mice that express normal and mutated amelogenins. |
Volume: |
86 |
Issue: |
4 |
Pages: |
331-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Partial rescue of the amelogenin null dental enamel phenotype. |
Volume: |
283 |
Issue: |
22 |
Pages: |
15056-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aryal YP |
Year: |
2019 |
Journal: |
J Cell Physiol |
Title: |
An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. |
Volume: |
234 |
Issue: |
11 |
Pages: |
20354-20365 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ota MS |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Amelogenin X impacts age-dependent increase of frequency and number in labial incisor grooves in C57BL/6. |
Volume: |
496 |
Issue: |
2 |
Pages: |
324-327 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen E |
Year: |
2003 |
Journal: |
Calcif Tissue Int |
Title: |
The small bovine amelogenin LRAP fails to rescue the amelogenin null phenotype. |
Volume: |
73 |
Issue: |
5 |
Pages: |
487-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2006 |
Journal: |
Eur J Oral Sci |
Title: |
Comparison of body weight and gene expression in amelogenin null and wild-type mice. |
Volume: |
114 Suppl 1 |
|
Pages: |
190-3; discussion 201-2, 381 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sehic A |
Year: |
2010 |
Journal: |
Eur J Oral Sci |
Title: |
Gene expression and dental enamel structure in developing mouse incisor. |
Volume: |
118 |
Issue: |
2 |
Pages: |
118-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tao J |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Circadian Rhythm Regulates Development of Enamel in Mouse Mandibular First Molar. |
Volume: |
11 |
Issue: |
8 |
Pages: |
e0159946 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shin NY |
Year: |
2020 |
Journal: |
J Biol Chem |
Title: |
Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor. |
Volume: |
295 |
Issue: |
7 |
Pages: |
1943-1959 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng X |
Year: |
2022 |
Journal: |
Bone |
Title: |
Effects of Fam83h truncation mutation on enamel developmental defects in male C57/BL6J mice. |
Volume: |
166 |
|
Pages: |
116595 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bronckers AL |
Year: |
2015 |
Journal: |
J Dent Res |
Title: |
Ameloblast Modulation and Transport of Cl⁻, Na⁺, and K⁺ during Amelogenesis. |
Volume: |
94 |
Issue: |
12 |
Pages: |
1740-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vieira AR |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Weaker dental enamel explains dental decay. |
Volume: |
10 |
Issue: |
4 |
Pages: |
e0124236 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stahl J |
Year: |
2013 |
Journal: |
Matrix Biol |
Title: |
Leucine rich amelogenin peptide alters ameloblast differentiation in vivo. |
Volume: |
32 |
Issue: |
7-8 |
Pages: |
432-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mutant Mouse Regional Resource Centers |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
|
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Buchner G |
Year: |
2000 |
Journal: |
Genomics |
Title: |
Identification of a new EGF-repeat-containing gene from human Xp22: a candidate for developmental disorders. |
Volume: |
65 |
Issue: |
1 |
Pages: |
16-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Manabe R |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Transcriptome-based systematic identification of extracellular matrix proteins. |
Volume: |
105 |
Issue: |
35 |
Pages: |
12849-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lau EC |
Year: |
1992 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Alternative splicing of the mouse amelogenin primary RNA transcript contributes to amelogenin heterogeneity. |
Volume: |
188 |
Issue: |
3 |
Pages: |
1253-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oida S |
Year: |
1996 |
Journal: |
DNA Seq |
Title: |
Molecular structure of the mouse amelogenin genomic DNA. |
Volume: |
6 |
Issue: |
5 |
Pages: |
307-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Snead ML |
Year: |
1985 |
Journal: |
Biochem Biophys Res Commun |
Title: |
DNA sequence for cloned cDNA for murine amelogenin reveal the amino acid sequence for enamel-specific protein. |
Volume: |
129 |
Issue: |
3 |
Pages: |
812-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rugarli EI |
Year: |
1995 |
Journal: |
Nat Genet |
Title: |
Different chromosomal localization of the Clcn4 gene in Mus spretus and C57BL/6J mice. |
Volume: |
10 |
Issue: |
4 |
Pages: |
466-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Vega S |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
TM14 is a new member of the fibulin family (fibulin-7) that interacts with extracellular matrix molecules and is active for cell binding. |
Volume: |
282 |
Issue: |
42 |
Pages: |
30878-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pasteris NG |
Year: |
1995 |
Journal: |
Mamm Genome |
Title: |
Cloning and regional localization of the mouse faciogenital dysplasia (Fgd1) gene. |
Volume: |
6 |
Issue: |
9 |
Pages: |
658-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo W |
Year: |
1996 |
Journal: |
Gene |
Title: |
Ahch, the mouse homologue of DAX1: cloning, characterization and synteny with GyK, the glycerol kinase locus. |
Volume: |
178 |
Issue: |
1-2 |
Pages: |
31-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ehrmann IE |
Year: |
1998 |
Journal: |
Hum Mol Genet |
Title: |
Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution. |
Volume: |
7 |
Issue: |
11 |
Pages: |
1725-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paine CT |
Year: |
1998 |
Journal: |
Connect Tissue Res |
Title: |
Identification of tuftelin- and amelogenin-interacting proteins using the yeast two-hybrid system. |
Volume: |
38 |
Issue: |
1-4 |
Pages: |
257-67;discussion 295-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Newton JM |
Year: |
1996 |
Journal: |
Genomics |
Title: |
Isolation and characterization of a mouse homolog of the X-linked ocular albinism (OA1) gene. |
Volume: |
37 |
Issue: |
2 |
Pages: |
219-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huq AH |
Year: |
1996 |
Journal: |
Genomics |
Title: |
Isolation, mapping, and functional expression of the mouse X chromosome glycerol kinase gene. |
Volume: |
36 |
Issue: |
3 |
Pages: |
530-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Montini E |
Year: |
1997 |
Journal: |
Hum Mol Genet |
Title: |
A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. |
Volume: |
6 |
Issue: |
7 |
Pages: |
1137-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Collignon J |
Year: |
1996 |
Journal: |
Development |
Title: |
A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2. |
Volume: |
122 |
Issue: |
2 |
Pages: |
509-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zeichner-David M |
Year: |
1997 |
Journal: |
Int J Dev Biol |
Title: |
Timing of the expression of enamel gene products during mouse tooth development. |
Volume: |
41 |
Issue: |
1 |
Pages: |
27-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu J |
Year: |
1995 |
Journal: |
Biochim Biophys Acta |
Title: |
Cloning and characterization of the mouse PIG-A gene. |
Volume: |
1255 |
Issue: |
3 |
Pages: |
344-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Snead ML |
Year: |
1998 |
Journal: |
Connect Tissue Res |
Title: |
Transgene animal model for protein expression and accumulation into forming enamel. |
Volume: |
38 |
Issue: |
1-4 |
Pages: |
279-86; discussion 295-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lagerström-Fermér M |
Year: |
1995 |
Journal: |
Genomics |
Title: |
Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta. |
Volume: |
26 |
Issue: |
1 |
Pages: |
159-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cantù C |
Year: |
2017 |
Journal: |
Sci Signal |
Title: |
A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation. |
Volume: |
10 |
Issue: |
465 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wang SK |
Year: |
2011 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Potential contribution of neural crest cells to dental enamel formation. |
Volume: |
415 |
Issue: |
1 |
Pages: |
114-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
RIKEN BioResource Center/RIKEN Genomic Sciences Center |
Year: |
2008 |
Journal: |
PhenoSITE, World Wide Web (URL: http://www.brc.riken.jp/lab/gsc/mouse/) |
Title: |
A Large Scale Mutagenesis Program in RIKEN GSC |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Catón J |
Year: |
2009 |
Journal: |
Dev Biol |
Title: |
Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors. |
Volume: |
328 |
Issue: |
2 |
Pages: |
493-505 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao H |
Year: |
2010 |
Journal: |
Dev Biol |
Title: |
Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21. |
Volume: |
347 |
Issue: |
2 |
Pages: |
289-300 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bouwman P |
Year: |
2000 |
Journal: |
EMBO J |
Title: |
Transcription factor Sp3 is essential for post-natal survival and late tooth development. |
Volume: |
19 |
Issue: |
4 |
Pages: |
655-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Connell DJ |
Year: |
2012 |
Journal: |
Sci Signal |
Title: |
A Wnt-bmp feedback circuit controls intertissue signaling dynamics in tooth organogenesis. |
Volume: |
5 |
Issue: |
206 |
Pages: |
ra4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rios H |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. |
Volume: |
25 |
Issue: |
24 |
Pages: |
11131-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eliason S |
Year: |
2022 |
Journal: |
J Biol Chem |
Title: |
HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis. |
Volume: |
298 |
Issue: |
9 |
Pages: |
102295 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie F |
Year: |
2022 |
Journal: |
J Biol Chem |
Title: |
N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis. |
Volume: |
298 |
Issue: |
12 |
Pages: |
102715 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ohazama A |
Year: |
2004 |
Journal: |
Dev Cell |
Title: |
A dual role for Ikk alpha in tooth development. |
Volume: |
6 |
Issue: |
2 |
Pages: |
219-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takahashi M |
Year: |
2020 |
Journal: |
Dev Dyn |
Title: |
Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Xu Y |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
CCAAT/enhancer-binding protein delta (C/EBPdelta) maintains amelogenin expression in the absence of C/EBPalpha in vivo. |
Volume: |
282 |
Issue: |
41 |
Pages: |
29882-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nie X |
Year: |
2020 |
Journal: |
Dev Biol |
Title: |
mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. |
Volume: |
467 |
Issue: |
1-2 |
Pages: |
77-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kyrylkova K |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e37670 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blackburn J |
Year: |
2015 |
Journal: |
J Dent Res |
Title: |
Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium. |
Volume: |
94 |
Issue: |
1 |
Pages: |
121-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Korobova O |
Year: |
1998 |
Journal: |
Genomics |
Title: |
Patchy fur, a mouse coat mutation associated with X-Y nondisjunction, maps to the pseudoautosomal boundary region. |
Volume: |
54 |
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