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Search results 1 to 100 out of 117 for Ang2

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
497229 | Ang2
Type: gene
Organism: rat
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Gene
783907 | ANG2
Type: gene
Organism: cattle
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Protein Coding Gene
MGI:104984 | Ang2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24235146 | J:207185
First Author: Ju R
Year: 2014
Journal: J Biol Chem
Title: Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.
Volume: 289
Issue: 1
Pages: 510-9
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Publication
21481792 | J:170979
First Author: Mazzieri R
Year: 2011
Journal: Cancer Cell
Title: Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.
Volume: 19
Issue: 4
Pages: 512-26
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Publication
32466219 | J:302415
 
First Author: Chatterjee A
Year: 2020
Journal: Int J Mol Sci
Title: Role of the Ang2-Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency.
Volume: 21
Issue: 10
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Publication
19825936 | J:154608
First Author: Harada K
Year: 2009
Journal: J Cell Sci
Title: Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis.
Volume: 122
Issue: Pt 21
Pages: 3923-30
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Publication
20133818 | J:158640
First Author: Fuxe J
Year: 2010
Journal: Am J Pathol
Title: Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation.
Volume: 176
Issue: 4
Pages: 2009-18
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Publication
20952594 | J:170783
First Author: Tabruyn SP
Year: 2010
Journal: Am J Pathol
Title: Angiopoietin-2-driven vascular remodeling in airway inflammation.
Volume: 177
Issue: 6
Pages: 3233-43
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Publication
21127017 | J:185336
First Author: Marteau L
Year: 2011
Journal: Cereb Cortex
Title: Angiopoietin-2 regulates cortical neurogenesis in the developing telencephalon.
Volume: 21
Issue: 7
Pages: 1695-702
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Publication
26348576 | J:226905
First Author: Le CT
Year: 2015
Journal: Am J Pathol
Title: Synergistic actions of blocking angiopoietin-2 and tumor necrosis factor-α in suppressing remodeling of blood vessels and lymphatics in airway inflammation.
Volume: 185
Issue: 11
Pages: 2949-68
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Publication
32149735 | J:294828
First Author: Li Z
Year: 2020
Journal: J Clin Invest
Title: Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS.
Volume: 130
Issue: 4
Pages: 1977-1990
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Publication
21857934 | J:176505
First Author: Wang JL
Year: 2011
Journal: PLoS One
Title: Calcium prevents tumorigenesis in a mouse model of colorectal cancer.
Volume: 6
Issue: 8
Pages: e22566
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Protein Coding Gene
MGP_129S1SvImJ_G0021277 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_104984 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021671 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020540 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021179 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021700 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020289 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020592 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_SPRETEiJ_G0021593 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
18477666 | J:138143
First Author: Rampon C
Year: 2008
Journal: Physiol Genomics
Title: Protocadherin 12 deficiency alters morphogenesis and transcriptional profile of the placenta.
Volume: 34
Issue: 2
Pages: 193-204
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Publication
8530072 | J:28832
First Author: Brown WE
Year: 1995
Journal: Genomics
Title: The mouse angiogenin gene family: structures of an angiogenin-related protein gene and two pseudogenes.
Volume: 29
Issue: 1
Pages: 200-6
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Publication
8633065 | J:32899
First Author: Nobile V
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Characterization of mouse angiogenin-related protein: implications for functional studies on angiogenin.
Volume: 93
Issue: 9
Pages: 4331-5
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Publication
23170778 | J:208392
First Author: Iyer S
Year: 2013
Journal: FEBS J
Title: Crystal structures of murine angiogenin-2 and -3-probing 'structure--function' relationships amongst angiogenin homologues.
Volume: 280
Issue: 1
Pages: 302-18
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Publication
15676279 | J:95949
First Author: Cho S
Year: 2005
Journal: Genomics
Title: The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.
Volume: 85
Issue: 2
Pages: 208-20
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
25576926 | J:219810
First Author: Qu X
Year: 2015
Journal: Dev Biol
Title: Tie1 is required for lymphatic valve and collecting vessel development.
Volume: 399
Issue: 1
Pages: 117-28
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Publication
25958091 | J:224939
First Author: Hare LM
Year: 2015
Journal: Dev Biol
Title: Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects.
Volume: 404
Issue: 1
Pages: 14-26
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
29065170 | J:251673
First Author: Pan L
Year: 2017
Journal: PLoS One
Title: Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis.
Volume: 12
Issue: 10
Pages: e0186635
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Publication
15225218 | J:91685
First Author: Heber-Katz E
Year: 2004
Journal: Wound Repair Regen
Title: Regeneration in MRL mice: further genetic loci controlling the ear hole closure trait using MRL and M.m. Castaneus mice.
Volume: 12
Issue: 3
Pages: 384-92
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Publication
34890862 | J:318908
 
First Author: Wilson RL
Year: 2022
Journal: Placenta
Title: Placental and fetal characteristics of the Ohia mouse line recapitulate outcomes in human hypoplastic left heart syndrome.
Volume: 117
Pages: 131-138
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Publication
28096417 | J:240742
First Author: Castañeda-Bueno M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK4.
Volume: 114
Issue: 5
Pages: E879-E886
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
25313067 | J:216684
First Author: Shibata S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation.
Volume: 111
Issue: 43
Pages: 15556-61
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Publication
17670746 | J:126723
First Author: Yao D
Year: 2007
Journal: J Biol Chem
Title: High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.
Volume: 282
Issue: 42
Pages: 31038-45
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
24285500 | J:206146
First Author: Zhang J
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Enhanced expression and activity of Nox2 and Nox4 in the macula densa in ANG II-induced hypertensive mice.
Volume: 306
Issue: 3
Pages: F344-50
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Publication
24829505 | J:211260
First Author: Nagami GT
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Effects of acid challenges on type 2 angiotensin II receptor-sensitive ammonia production by the proximal tubule.
Volume: 307
Issue: 1
Pages: F53-7
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Publication
24099770 | J:211404
First Author: Wang X
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Regulation of autophagy and apoptosis in response to angiotensin II in HL-1 cardiomyocytes.
Volume: 440
Issue: 4
Pages: 696-700
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Publication
25962877 | J:224884
 
First Author: Choi HJ
Year: 2015
Journal: Nat Commun
Title: Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2.
Volume: 6
Pages: 6943
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Publication
24874427 | J:247084
First Author: Dharaneeswaran H
Year: 2014
Journal: Circ Res
Title: FOXO1-mediated activation of Akt plays a critical role in vascular homeostasis.
Volume: 115
Issue: 2
Pages: 238-251
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Publication
31338035 | J:286013
 
First Author: Outhwaite JE
Year: 2019
Journal: Front Physiol
Title: Secondary Placental Defects in Cxadr Mutant Mice.
Volume: 10
Pages: 622
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Publication
37843277 | J:341637
 
First Author: Lee E
Year: 2023
Journal: J Clin Invest
Title: Angiopoietin-2 blockade suppresses growth of liver metastases from pancreatic neuroendocrine tumors by promoting T cell recruitment.
Volume: 133
Issue: 20
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GXD Expression
GXD Expression
   
Probe: MGI:5750565
Assay Type: RNA in situ
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5750569
Age: embryonic day 14.5
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5750565
Assay Type: RNA in situ
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5750569
Age: embryonic day 16.5
Specimen Label: 1E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5750559
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5750582
Age: embryonic day 14.5
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5750559
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5750582
Age: embryonic day 16.5
Specimen Label: 1F
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5750565
Assay Type: RNA in situ
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5750569
Age: embryonic day 14.5
Specimen Label: 1A
Detected: true
Specimen Num: 1
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
27960088 | J:238058
First Author: Park JS
Year: 2016
Journal: Cancer Cell
Title: Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment.
Volume: 30
Issue: 6
Pages: 953-967
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Protein Coding Gene
MGI:1202890 | Angpt2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
F6TKZ2
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein Domain
IPR014812 | Vps51
Type: Family
Description: The VFT tethering complex (also known as GARP complex, Golgi associated retrograde protein complex, Vps53 tethering complex) is a conserved eukaryotic docking complex which is involved in recycling of proteins from endosomes to the late Golgi. Vps51 (also known as Ang2 or Vps67) is a subunit of VFT and interacts with the SNARE Tlg1 []. It is also part of the endosome-associated recycling protein (EARP) complex which is structurally related to GARP complex [].
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HT Experiment
GSE178659 | The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
9204896 | J:46939
First Author: Maisonpierre PC
Year: 1997
Journal: Science
Title: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.
Volume: 277
Issue: 5322
Pages: 55-60
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Publication
34407407 | J:323584
First Author: Luck R
Year: 2021
Journal: Cell Rep
Title: The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner.
Volume: 36
Issue: 7
Pages: 109522
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Publication
28508859 | J:249950
 
First Author: Park DY
Year: 2017
Journal: Nat Commun
Title: Plastic roles of pericytes in the blood-retinal barrier.
Volume: 8
Pages: 15296
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Publication
23954784 | J:202765
First Author: Minami T
Year: 2013
Journal: Cell Rep
Title: The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases.
Volume: 4
Issue: 4
Pages: 709-23
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Publication
18514180 | J:137723
First Author: Dellinger M
Year: 2008
Journal: Dev Biol
Title: Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice.
Volume: 319
Issue: 2
Pages: 309-20
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Publication
24458641 | J:207486
First Author: Hu J
Year: 2014
Journal: Science
Title: Endothelial cell-derived angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat.
Volume: 343
Issue: 6169
Pages: 416-9
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Publication
19217887 | J:147388
First Author: Hato T
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Angiopoietins contribute to lung development by regulating pulmonary vascular network formation.
Volume: 381
Issue: 2
Pages: 218-23
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Publication
25635707 | J:219789
 
First Author: Hakanpaa L
Year: 2015
Journal: Nat Commun
Title: Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
Volume: 6
Pages: 5962
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Publication
25030698 | J:214956
First Author: Zheng W
Year: 2014
Journal: Genes Dev
Title: Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions.
Volume: 28
Issue: 14
Pages: 1592-603
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Publication
25704811 | J:224177
First Author: Keskin D
Year: 2015
Journal: Cell Rep
Title: Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2.
Volume: 10
Issue: 7
Pages: 1066-81
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Publication
11801735 | J:74294
First Author: Mochizuki Y
Year: 2002
Journal: J Cell Sci
Title: Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn.
Volume: 115
Issue: Pt 1
Pages: 175-83
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Publication
11500985 | J:70709
First Author: Pham VN
Year: 2001
Journal: Dev Dyn
Title: Isolation and expression analysis of three zebrafish angiopoietin genes.
Volume: 221
Issue: 4
Pages: 470-4
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Publication
25490450 | J:217745
First Author: Srivastava K
Year: 2014
Journal: Cancer Cell
Title: Postsurgical adjuvant tumor therapy by combining anti-angiopoietin-2 and metronomic chemotherapy limits metastatic growth.
Volume: 26
Issue: 6
Pages: 880-895
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Publication
12377769 | -
First Author: Siniossoglou S
Year: 2002
Journal: J Biol Chem
Title: Vps51p links the VFT complex to the SNARE Tlg1p.
Volume: 277
Issue: 50
Pages: 48318-24
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Protein
Q3UVL4
Organism: Mus musculus/domesticus
Length: 782  
Fragment?: false
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Publication
25799061 | J:225569
First Author: Schindler C
Year: 2015
Journal: Nat Cell Biol
Title: EARP is a multisubunit tethering complex involved in endocytic recycling.
Volume: 17
Issue: 5
Pages: 639-50
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Publication
19557008 | J:169284
First Author: Lee HJ
Year: 2009
Journal: Cell Death Differ
Title: Ninjurin1 mediates macrophage-induced programmed cell death during early ocular development.
Volume: 16
Issue: 10
Pages: 1395-407
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Publication
22922221 | J:197503
First Author: Wang L
Year: 2012
Journal: Neurobiol Dis
Title: Thymosin β4 promotes the recovery of peripheral neuropathy in type II diabetic mice.
Volume: 48
Issue: 3
Pages: 546-55
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Publication
22227562 | J:196034
First Author: Bhandari V
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2.
Volume: 46
Issue: 5
Pages: 668-76
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Publication
35373291 | J:322779
First Author: Jakab M
Year: 2022
Journal: Cancer Res
Title: Tie2 Receptor in Tumor-Infiltrating Macrophages Is Dispensable for Tumor Angiogenesis and Tumor Relapse after Chemotherapy.
Volume: 82
Issue: 7
Pages: 1353-1364
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Publication
35440711 | J:324181
First Author: Yang Y
Year: 2022
Journal: Commun Biol
Title: Med23 supports angiogenesis and maintains vascular integrity through negative regulation of angiopoietin2 expression.
Volume: 5
Issue: 1
Pages: 374
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Publication
27548530 | J:237295
First Author: Korhonen EA
Year: 2016
Journal: J Clin Invest
Title: Tie1 controls angiopoietin function in vascular remodeling and inflammation.
Volume: 126
Issue: 9
Pages: 3495-510
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Publication
24820020 | J:212750
First Author: Burrell K
Year: 2014
Journal: Cancer Res
Title: VEGF regulates region-specific localization of perivascular bone marrow-derived cells in glioblastoma.
Volume: 74
Issue: 14
Pages: 3727-39
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Publication
23863629 | J:201411
     
First Author: Ziegler T
Year: 2013
Journal: J Clin Invest
Title: Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis.
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Publication
22848540 | J:189700
First Author: Mammoto T
Year: 2012
Journal: PLoS One
Title: LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway.
Volume: 7
Issue: 7
Pages: e41596
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