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Search results 1 to 100 out of 103 for Ang2

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0.044s
Type Details Score
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Ju R
Year: 2014
Journal: J Biol Chem
Title: Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.
Volume: 289
Issue: 1
Pages: 510-9
Publication
First Author: Mazzieri R
Year: 2011
Journal: Cancer Cell
Title: Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.
Volume: 19
Issue: 4
Pages: 512-26
Publication
First Author: Harada K
Year: 2009
Journal: J Cell Sci
Title: Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis.
Volume: 122
Issue: Pt 21
Pages: 3923-30
Publication
First Author: Fuxe J
Year: 2010
Journal: Am J Pathol
Title: Angiopoietin/Tie2 signaling transforms capillaries into venules primed for leukocyte trafficking in airway inflammation.
Volume: 176
Issue: 4
Pages: 2009-18
Publication
First Author: Tabruyn SP
Year: 2010
Journal: Am J Pathol
Title: Angiopoietin-2-driven vascular remodeling in airway inflammation.
Volume: 177
Issue: 6
Pages: 3233-43
Publication
First Author: Marteau L
Year: 2011
Journal: Cereb Cortex
Title: Angiopoietin-2 regulates cortical neurogenesis in the developing telencephalon.
Volume: 21
Issue: 7
Pages: 1695-702
Publication
First Author: Le CT
Year: 2015
Journal: Am J Pathol
Title: Synergistic actions of blocking angiopoietin-2 and tumor necrosis factor-α in suppressing remodeling of blood vessels and lymphatics in airway inflammation.
Volume: 185
Issue: 11
Pages: 2949-68
Publication
First Author: Li Z
Year: 2020
Journal: J Clin Invest
Title: Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS.
Volume: 130
Issue: 4
Pages: 1977-1990
Publication  
First Author: Chatterjee A
Year: 2020
Journal: Int J Mol Sci
Title: Role of the Ang2-Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency.
Volume: 21
Issue: 10
Publication
First Author: Wang JL
Year: 2011
Journal: PLoS One
Title: Calcium prevents tumorigenesis in a mouse model of colorectal cancer.
Volume: 6
Issue: 8
Pages: e22566
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Cho S
Year: 2005
Journal: Genomics
Title: The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.
Volume: 85
Issue: 2
Pages: 208-20
Publication
First Author: Rampon C
Year: 2008
Journal: Physiol Genomics
Title: Protocadherin 12 deficiency alters morphogenesis and transcriptional profile of the placenta.
Volume: 34
Issue: 2
Pages: 193-204
Publication
First Author: Brown WE
Year: 1995
Journal: Genomics
Title: The mouse angiogenin gene family: structures of an angiogenin-related protein gene and two pseudogenes.
Volume: 29
Issue: 1
Pages: 200-6
Publication
First Author: Nobile V
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Characterization of mouse angiogenin-related protein: implications for functional studies on angiogenin.
Volume: 93
Issue: 9
Pages: 4331-5
Publication
First Author: Iyer S
Year: 2013
Journal: FEBS J
Title: Crystal structures of murine angiogenin-2 and -3-probing 'structure--function' relationships amongst angiogenin homologues.
Volume: 280
Issue: 1
Pages: 302-18
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication
First Author: Hare LM
Year: 2015
Journal: Dev Biol
Title: Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects.
Volume: 404
Issue: 1
Pages: 14-26
Publication
First Author: Qu X
Year: 2015
Journal: Dev Biol
Title: Tie1 is required for lymphatic valve and collecting vessel development.
Volume: 399
Issue: 1
Pages: 117-28
Publication
First Author: Pan L
Year: 2017
Journal: PLoS One
Title: Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis.
Volume: 12
Issue: 10
Pages: e0186635
Publication
First Author: Heber-Katz E
Year: 2004
Journal: Wound Repair Regen
Title: Regeneration in MRL mice: further genetic loci controlling the ear hole closure trait using MRL and M.m. Castaneus mice.
Volume: 12
Issue: 3
Pages: 384-92
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication
First Author: Yao D
Year: 2007
Journal: J Biol Chem
Title: High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.
Volume: 282
Issue: 42
Pages: 31038-45
Publication
First Author: Zhang J
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Enhanced expression and activity of Nox2 and Nox4 in the macula densa in ANG II-induced hypertensive mice.
Volume: 306
Issue: 3
Pages: F344-50
Publication
First Author: Nagami GT
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Effects of acid challenges on type 2 angiotensin II receptor-sensitive ammonia production by the proximal tubule.
Volume: 307
Issue: 1
Pages: F53-7
Publication
First Author: Wang X
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Regulation of autophagy and apoptosis in response to angiotensin II in HL-1 cardiomyocytes.
Volume: 440
Issue: 4
Pages: 696-700
Publication  
First Author: Choi HJ
Year: 2015
Journal: Nat Commun
Title: Yes-associated protein regulates endothelial cell contact-mediated expression of angiopoietin-2.
Volume: 6
Pages: 6943
Publication
First Author: Dharaneeswaran H
Year: 2014
Journal: Circ Res
Title: FOXO1-mediated activation of Akt plays a critical role in vascular homeostasis.
Volume: 115
Issue: 2
Pages: 238-251
Publication  
First Author: Outhwaite JE
Year: 2019
Journal: Front Physiol
Title: Secondary Placental Defects in Cxadr Mutant Mice.
Volume: 10
Pages: 622
GXD Expression    
Probe: MGI:5750565
Assay Type: RNA in situ
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5750569
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5750565
Assay Type: RNA in situ
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5750569
Age: embryonic day 16.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5750559
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5750582
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5750559
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5750582
Age: embryonic day 16.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5750565
Assay Type: RNA in situ
Annotation Date: 2016-02-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5750569
Age: embryonic day 14.5
Detected: true
Specimen Num: 1
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Park JS
Year: 2016
Journal: Cancer Cell
Title: Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment.
Volume: 30
Issue: 6
Pages: 953-967
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 120  
Fragment?: true
Protein Domain
Type: Family
Description: The VFT tethering complex (also known as GARP complex, Golgi associated retrograde protein complex, Vps53 tethering complex) is a conserved eukaryotic docking complex which is involved in recycling of proteins from endosomes to the late Golgi. Vps51 (also known as Ang2 or Vps67) is a subunit of VFT and interacts with the SNARE Tlg1 []. It is also part of the endosome-associated recycling protein (EARP) complex which is structurally related to GARP complex [].
Publication
First Author: Siniossoglou S
Year: 2002
Journal: J Biol Chem
Title: Vps51p links the VFT complex to the SNARE Tlg1p.
Volume: 277
Issue: 50
Pages: 48318-24
Publication
First Author: Maisonpierre PC
Year: 1997
Journal: Science
Title: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.
Volume: 277
Issue: 5322
Pages: 55-60
Publication  
First Author: Park DY
Year: 2017
Journal: Nat Commun
Title: Plastic roles of pericytes in the blood-retinal barrier.
Volume: 8
Pages: 15296
Publication
First Author: Zheng W
Year: 2014
Journal: Genes Dev
Title: Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions.
Volume: 28
Issue: 14
Pages: 1592-603
Publication
First Author: Dellinger M
Year: 2008
Journal: Dev Biol
Title: Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice.
Volume: 319
Issue: 2
Pages: 309-20
Publication
First Author: Hu J
Year: 2014
Journal: Science
Title: Endothelial cell-derived angiopoietin-2 controls liver regeneration as a spatiotemporal rheostat.
Volume: 343
Issue: 6169
Pages: 416-9
Publication
First Author: Hato T
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Angiopoietins contribute to lung development by regulating pulmonary vascular network formation.
Volume: 381
Issue: 2
Pages: 218-23
Publication
First Author: Keskin D
Year: 2015
Journal: Cell Rep
Title: Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2.
Volume: 10
Issue: 7
Pages: 1066-81
Publication  
First Author: Hakanpaa L
Year: 2015
Journal: Nat Commun
Title: Endothelial destabilization by angiopoietin-2 via integrin β1 activation.
Volume: 6
Pages: 5962
Publication
First Author: Minami T
Year: 2013
Journal: Cell Rep
Title: The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases.
Volume: 4
Issue: 4
Pages: 709-23
Publication
First Author: Mochizuki Y
Year: 2002
Journal: J Cell Sci
Title: Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn.
Volume: 115
Issue: Pt 1
Pages: 175-83
Publication
First Author: Pham VN
Year: 2001
Journal: Dev Dyn
Title: Isolation and expression analysis of three zebrafish angiopoietin genes.
Volume: 221
Issue: 4
Pages: 470-4
Publication
First Author: Srivastava K
Year: 2014
Journal: Cancer Cell
Title: Postsurgical adjuvant tumor therapy by combining anti-angiopoietin-2 and metronomic chemotherapy limits metastatic growth.
Volume: 26
Issue: 6
Pages: 880-895
Protein
Organism: Mus musculus
Length: 782  
Fragment?: false
Publication
First Author: Schindler C
Year: 2015
Journal: Nat Cell Biol
Title: EARP is a multisubunit tethering complex involved in endocytic recycling.
Volume: 17
Issue: 5
Pages: 639-50
Publication
First Author: Korhonen EA
Year: 2016
Journal: J Clin Invest
Title: Tie1 controls angiopoietin function in vascular remodeling and inflammation.
Volume: 126
Issue: 9
Pages: 3495-510
Publication
First Author: Rajput C
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: MicroRNA-150 Suppression of Angiopoetin-2 Generation and Signaling Is Crucial for Resolving Vascular Injury.
Volume: 36
Issue: 2
Pages: 380-8
Publication
First Author: Wang L
Year: 2012
Journal: Neurobiol Dis
Title: Thymosin β4 promotes the recovery of peripheral neuropathy in type II diabetic mice.
Volume: 48
Issue: 3
Pages: 546-55
Publication
First Author: Bhandari V
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2.
Volume: 46
Issue: 5
Pages: 668-76
Publication
First Author: Kim M
Year: 2016
Journal: J Clin Invest
Title: Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation.
Volume: 126
Issue: 9
Pages: 3511-25
Publication
First Author: Burrell K
Year: 2014
Journal: Cancer Res
Title: VEGF regulates region-specific localization of perivascular bone marrow-derived cells in glioblastoma.
Volume: 74
Issue: 14
Pages: 3727-39
Publication
First Author: Qiu Y
Year: 2016
Journal: Acta Diabetol
Title: Nucleoside diphosphate kinase B deficiency causes a diabetes-like vascular pathology via up-regulation of endothelial angiopoietin-2 in the retina.
Volume: 53
Issue: 1
Pages: 81-9
Publication
First Author: Daly C
Year: 2018
Journal: Sci Rep
Title: Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.
Volume: 8
Issue: 1
Pages: 505
Publication
First Author: Kobayashi S
Year: 2015
Journal: Genes Cells
Title: Hypoxia-inducible factor-3α promotes angiogenic activity of pulmonary endothelial cells by repressing the expression of the VE-cadherin gene.
Volume: 20
Issue: 3
Pages: 224-41
Publication      
First Author: Ziegler T
Year: 2013
Journal: J Clin Invest
Title: Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis.
Publication
First Author: Mammoto T
Year: 2012
Journal: PLoS One
Title: LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathway.
Volume: 7
Issue: 7
Pages: e41596
Publication
First Author: Lee HJ
Year: 2009
Journal: Cell Death Differ
Title: Ninjurin1 mediates macrophage-induced programmed cell death during early ocular development.
Volume: 16
Issue: 10
Pages: 1395-407
Publication
First Author: Colen KL
Year: 1999
Journal: J Pediatr Surg
Title: Vascular development in the mouse embryonic pancreas and lung.
Volume: 34
Issue: 5
Pages: 781-5
Publication
First Author: Nambu H
Year: 2005
Journal: J Cell Physiol
Title: Angiopoietin 1 prevents retinal detachment in an aggressive model of proliferative retinopathy, but has no effect on established neovascularization.
Volume: 204
Issue: 1
Pages: 227-35
Publication
First Author: Shimoda H
Year: 2009
Journal: Histochem Cell Biol
Title: Immunohistochemical demonstration of Angiopoietin-2 in lymphatic vascular development.
Volume: 131
Issue: 2
Pages: 231-8
Publication
First Author: Falcón BL
Year: 2009
Journal: Am J Pathol
Title: Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels.
Volume: 175
Issue: 5
Pages: 2159-70
Publication
First Author: Pietilä R
Year: 2012
Journal: J Cell Sci
Title: Ligand oligomerization state controls Tie2 receptor trafficking and angiopoietin-2-specific responses.
Volume: 125
Issue: Pt 9
Pages: 2212-23
Publication
First Author: He T
Year: 2014
Journal: J Pathol
Title: MicroRNA-542-3p inhibits tumour angiogenesis by targeting angiopoietin-2.
Volume: 232
Issue: 5
Pages: 499-508
Publication
First Author: Shen J
Year: 2014
Journal: J Clin Invest
Title: Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature.
Volume: 124
Issue: 10
Pages: 4564-76
Publication
First Author: Pedrosa AR
Year: 2019
Journal: Cancer Res
Title: Tumor Angiogenesis Is Differentially Regulated by Phosphorylation of Endothelial Cell Focal Adhesion Kinase Tyrosines-397 and -861.
Volume: 79
Issue: 17
Pages: 4371-4386
Publication
First Author: Gengenbacher N
Year: 2021
Journal: Cancer Discov
Title: Timed Ang2-Targeted Therapy Identifies the Angiopoietin-Tie Pathway as Key Regulator of Fatal Lymphogenous Metastasis.
Volume: 11
Issue: 2
Pages: 424-445
Publication
First Author: Cai Q
Year: 2012
Journal: Dev Biol
Title: Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation.
Volume: 367
Issue: 1
Pages: 40-54
Publication
First Author: van Tuyl M
Year: 2007
Journal: Dev Biol
Title: Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs.
Volume: 303
Issue: 2
Pages: 514-26
Publication
First Author: Holopainen T
Year: 2012
Journal: J Natl Cancer Inst
Title: Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis.
Volume: 104
Issue: 6
Pages: 461-75
Publication
First Author: Daley SK
Year: 2019
Journal: Inflamm Bowel Dis
Title: Role of Lymphatic Deficiency in the Pathogenesis and Progression of Inflammatory Bowel Disease to Colorectal Cancer in an Experimental Mouse Model.
Volume: 25
Issue: 12
Pages: 1919-1926