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Search results 1 to 88 out of 88 for Angptl8

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
55908 | ANGPTL8
Type: gene
Organism: human
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Gene
106994638 | ANGPTL8
Type: gene
Organism: macaque, rhesus
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Gene
107990273 | angptl8
Type: gene
Organism: zebrafish
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Gene
100361444 | Angptl8
Type: gene
Organism: rat
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Gene
100613809 | ANGPTL8
Type: gene
Organism: chimpanzee
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Gene
101902412 | ANGPTL8
Type: gene
Organism: cattle
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Gene
102155149 | ANGPTL8
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:3643534 | Angptl8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR026614 | ANGPTL8
Type: Family
Description: Angiopoietin-like protein 8 (ANGPTL8), also known as betatrophin or lipasin, is a regulator of lipid metabolism [, , ].
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Publication
22569073 | J:187261
First Author: Ren G
Year: 2012
Journal: Am J Physiol Endocrinol Metab
Title: Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism.
Volume: 303
Issue: 3
Pages: E334-51
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Publication
22809513 | J:188548
First Author: Zhang R
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels.
Volume: 424
Issue: 4
Pages: 786-92
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Publication
31388006 | J:281162
First Author: Chen S
Year: 2019
Journal: Nat Commun
Title: Angptl8 mediates food-driven resetting of hepatic circadian clock in mice.
Volume: 10
Issue: 1
Pages: 3518
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Publication
35851270 | J:326803
First Author: Hu L
Year: 2022
Journal: Cell Death Dis
Title: ANGPTL8 is a negative regulator in pathological cardiac hypertrophy.
Volume: 13
Issue: 7
Pages: 621
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Publication
32730227 | J:301815
 
First Author: Oldoni F
Year: 2020
Journal: JCI Insight
Title: ANGPTL8 has both endocrine and autocrine effects on substrate utilization.
Volume: 5
Issue: 17
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Publication
28204173 | J:247999
First Author: Gusarova V
Year: 2017
Journal: Endocrinology
Title: ANGPTL8 Blockade With a Monoclonal Antibody Promotes Triglyceride Clearance, Energy Expenditure, and Weight Loss in Mice.
Volume: 158
Issue: 5
Pages: 1252-1259
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Publication
24043787 | J:217262
First Author: Wang Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis.
Volume: 110
Issue: 40
Pages: 16109-14
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Publication
28413163 | J:242697
First Author: Haller JF
Year: 2017
Journal: J Lipid Res
Title: ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance.
Volume: 58
Issue: 6
Pages: 1166-1173
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Publication
29031715 | J:264985
First Author: Chi X
Year: 2017
Journal: Mol Metab
Title: ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase.
Volume: 6
Issue: 10
Pages: 1137-1149
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Publication
36034432 | J:327919
 
First Author: Tang J
Year: 2022
Journal: Front Endocrinol (Lausanne)
Title: ANGPTL8 promotes adipogenic differentiation of mesenchymal stem cells: potential role in ectopic lipid deposition.
Volume: 13
Pages: 927763
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Publication
38211696 | J:346397
 
First Author: Meng M
Year: 2024
Journal: Metabolism
Title: Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner.
Volume: 152
Pages: 155784
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Publication
32154742 | J:294323
First Author: Zhang L
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Regulation of ANGPTL8 in liver and adipose tissue by nutritional and hormonal signals and its effect on glucose homeostasis in mice.
Volume: 318
Issue: 5
Pages: E613-E624
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Publication
23261442 | -
First Author: Fu Z
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family.
Volume: 430
Issue: 3
Pages: 1126-31
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Protein
Q8R1L8
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Protein
A0A0A0R784
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: false
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Protein
Q80WX2
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Protein
A0A1P9FG12
Organism: Mus musculus/domesticus
Length: 183  
Fragment?: true
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Publication
25417115 | J:217383
First Author: Gusarova V
Year: 2014
Journal: Cell
Title: ANGPTL8/betatrophin does not control pancreatic beta cell expansion.
Volume: 159
Issue: 3
Pages: 691-6
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Publication
36494038 | J:351114
First Author: Yang YY
Year: 2023
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice.
Volume: 1869
Issue: 2
Pages: 166619
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Publication
33684391 | J:351115
 
First Author: Yang YY
Year: 2021
Journal: Biochem Pharmacol
Title: Angiopoietin-like proteins 8 knockout reduces intermittent hypoxia-induced vascular remodeling in a murine model of obstructive sleep apnea.
Volume: 186
Pages: 114502
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Publication
26569053 | J:250638
First Author: Zhang Y
Year: 2016
Journal: Biochim Biophys Acta
Title: Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase.
Volume: 1861
Issue: 2
Pages: 130-137
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Publication
23150577 | J:192349
First Author: Quagliarini F
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Atypical angiopoietin-like protein that regulates ANGPTL3.
Volume: 109
Issue: 48
Pages: 19751-6
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Publication
31470507 | J:292693
 
First Author: Huang JW
Year: 2019
Journal: Int J Mol Sci
Title: Loss of Glycine N-Methyltransferase Associates with Angiopoietin-Like Protein 8 Expression in High Fat-Diet-Fed Mice.
Volume: 20
Issue: 17
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Protein Coding Gene
MGP_CAROLIEiJ_G0031884 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034464 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034433 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034145 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3643534 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034954 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034118 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034277 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034220 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034362 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034263 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033173 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033583 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014750 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033008 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
24353178 | J:217254
First Author: Jiao Y
Year: 2014
Journal: Diabetes
Title: Elevated mouse hepatic betatrophin expression does not increase human β-cell replication in the transplant setting.
Volume: 63
Issue: 4
Pages: 1283-8
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Publication
23623304 | J:197679
First Author: Yi P
Year: 2013
Journal: Cell
Title: Betatrophin: a hormone that controls pancreatic β cell proliferation.
Volume: 153
Issue: 4
Pages: 747-58
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Publication
26687026 | J:349632
 
First Author: Fu Z
Year: 2015
Journal: Sci Rep
Title: A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase.
Volume: 5
Pages: 18502
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Publication
25954050 | J:224940
First Author: Wang Y
Year: 2015
Journal: J Lipid Res
Title: Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion.
Volume: 56
Issue: 7
Pages: 1296-307
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Publication
29768498 | J:267654
First Author: Saul MC
Year: 2018
Journal: PLoS One
Title: Genomic variants in an inbred mouse model predict mania-like behaviors.
Volume: 13
Issue: 5
Pages: e0197624
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Publication
20562862 | J:161922
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
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Publication
- | J:171883
     
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
32561878 | J:294081
First Author: Watanabe T
Year: 2020
Journal: Sci Rep
Title: Transcriptional Regulation of the Angptl8 Gene by Hepatocyte Nuclear Factor-1 in the Murine Liver.
Volume: 10
Issue: 1
Pages: 9999
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Interaction Experiment
Zhang Y (2017)
Description: ANGPTL8 negatively regulates NF-B activation by facilitating selective autophagic degradation of IKK.
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Allele
Angptl8<em2Smoc> | MGI:7288264
Name: angiopoietin-like 8; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
29255244 | -
First Author: Zhang Y
Year: 2017
Journal: Nat Commun
Title: ANGPTL8 negatively regulates NF-κB activation by facilitating selective autophagic degradation of IKKγ.
Volume: 8
Issue: 1
Pages: 2164
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Allele
Angptl8<em1Smoc> | MGI:7288263
Name: angiopoietin-like 8; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6354538 | C57BL/6JSmoc-Angptl8<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6770557 | C57BL/6JSmoc-Angptl8<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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