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Search results 1 to 100 out of 108 for Aopep

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0.14s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Aminopeptidase O (MEROPS identifier M01.028) is an intracellular aminopeptidase with a preference for arginyl bonds. It converts angiotensin III to angiotensin IV. In common with aminopeptidase B and leukotriene A4 hydrolase, aminopeptidase O has a C-terminal extension containing ARM-repeats (named after the Drosophila protein armadillo) [[cite:PUB00079145]]. There is a also a nucleolar location signal located between the peptidase and ARM-repeat domains. Aminopeptidase O has been localized to the nucleolus, and in the mouse a shorter isoform, generated by alternative initiation, is found in adult and embryonic blood vessels, mainly in the endothial and smooth muscle cells [[cite:PUB00079146]]. The AOPEP gene also includes a cluster of microRNAs, one of which modulates expression of the Mef2c gene which encodes myocyte-specific enhancer factor 2C [[cite:PUB00079147]]. It is possible that aminopeptidase O is involved in development of vasculature in the embryo and control of blood pressure.
Publication
First Author: Díaz-Perales A
Year: 2005
Journal: J Biol Chem
Title: Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase.
Volume: 280
Issue: 14
Pages: 14310-7
Publication
First Author: Axton R
Year: 2008
Journal: J Cell Biochem
Title: Aminopeptidase O contains a functional nucleolar localization signal and is implicated in vascular biology.
Volume: 103
Issue: 4
Pages: 1171-82
Protein
Organism: Mus musculus
Length: 45  
Fragment?: false
Publication
First Author: Chinchilla A
Year: 2011
Journal: Cardiovasc Res
Title: MicroRNA profiling during mouse ventricular maturation: a role for miR-27 modulating Mef2c expression.
Volume: 89
Issue: 1
Pages: 98-108
Protein
Organism: Mus musculus
Length: 177  
Fragment?: true
Protein
Organism: Mus musculus
Length: 159  
Fragment?: true
Protein
Organism: Mus musculus
Length: 155  
Fragment?: true
Protein
Organism: Mus musculus
Length: 69  
Fragment?: true
Protein
Organism: Mus musculus
Length: 182  
Fragment?: true
Protein
Organism: Mus musculus
Length: 167  
Fragment?: true
Protein
Organism: Mus musculus
Length: 110  
Fragment?: true
Protein
Organism: Mus musculus
Length: 170  
Fragment?: true
Protein
Organism: Mus musculus
Length: 817  
Fragment?: false
Protein
Organism: Mus musculus
Length: 823  
Fragment?: false
Protein
Organism: Mus musculus
Length: 822  
Fragment?: false
Protein
Organism: Mus musculus
Length: 715  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Kong X
Year: 2015
Journal: Diabetes
Title: Glucocorticoids transcriptionally regulate miR-27b expression promoting body fat accumulation via suppressing the browning of white adipose tissue.
Volume: 64
Issue: 2
Pages: 393-404
Publication
First Author: Shen L
Year: 2016
Journal: PLoS One
Title: MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes.
Volume: 11
Issue: 2
Pages: e0148532
GXD Expression      
Probe: MGI:4361152
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4361154
Age: postnatal month 1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:4361153
Age: postnatal month 1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4361152
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4361154
Age: postnatal month 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4361153
Age: postnatal month 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:4361138
Age: embryonic day 11.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:4361138
Age: embryonic day 11.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:4361138
Age: embryonic day 11.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4361152
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4361154
Age: postnatal month 1
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4361153
Age: postnatal month 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4361152
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4361154
Age: postnatal month 1
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4361153
Age: postnatal month 1
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4361152
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:4361154
Age: postnatal month 1
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:4361153
Age: postnatal month 1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4361152
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4361154
Age: postnatal month 1
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4361153
Age: postnatal month 1
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4361152
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4361154
Age: postnatal month 1
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:4361122
Assay Type: Northern blot
Annotation Date: 2009-10-12
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:4361153
Age: postnatal month 1
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the vasculature of the heart.
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the vasculature of the heart.
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the vasculature of the kidney.
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the vasculature of the spleen.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4361122
Assay Type: RNA in situ
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274315
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:4361144
Age: embryonic day 9.5
Note: Expression is in intersomitic vessels.
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274315
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4361145
Age: embryonic day 9.5
Note: Expression is throughout the vasculature and in the capillary plexus of the head. Expression is strong in intersomitic vessels.
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3268828
Pattern: Diffuse
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the intercalated discs of cardiomyocytes.
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the vasculature of the liver and skeletal muscle.
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the vasculature of the liver and skeletal muscle.
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3517728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the endothelial and smooth muscle layer of the aorta.
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1860128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the endothelial and smooth muscle layer of the aorta.
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the vasculature of the spleen.
Detected: true
Specimen Num: 3
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1620413
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:4361145
Age: embryonic day 8.5
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the vasculature of the kidney.
Detected: true
Specimen Num: 4
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3518228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2009-10-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3517628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4361145
Age: postnatal adult
Note: Expression is in the endothelial and smooth muscle layer of the aorta.
Detected: true
Specimen Num: 7
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics, the Protein Information Resource and the Protein Ontology Consortium
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations