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Search results 1 to 100 out of 473 for Apaf1

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
317 | APAF1
Type: gene
Organism: human
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Gene
452153 | APAF1
Type: gene
Organism: chimpanzee
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Gene
482620 | APAF1
Type: gene
Organism: dog, domestic
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Gene
537782 | APAF1
Type: gene
Organism: cattle
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Gene
417926 | APAF1
Type: gene
Organism: chicken
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Gene
58131 | apaf1
Type: gene
Organism: zebrafish
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Gene
694164 | APAF1
Type: gene
Organism: macaque, rhesus
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Gene
100127738 | apaf1
Type: gene
Organism: frog, western clawed
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Gene
78963 | Apaf1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1306796 | Apaf1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:4417773
Assay Type: RNA in situ
Annotation Date: 2022-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7294500
Age: embryonic day 14.5
Image: S2 APAF1
Specimen Label: S2 APAF1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6167530
Assay Type: RNA in situ
Annotation Date: 2022-06-30
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7294510
Age: postnatal day 56
Image: S3 APAF1
Specimen Label: S3 APAF1
Detected: true
Specimen Num: 1
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Gene
51074 | APIP
Type: gene
Organism: human
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Gene
100128086 | LOC100128086
Type: gene
Organism: human
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Publication
9753321 | J:49841
First Author: Yoshida H
Year: 1998
Journal: Cell
Title: Apaf1 is required for mitochondrial pathways of apoptosis and brain development.
Volume: 94
Issue: 6
Pages: 739-50
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Publication
23892366 | J:201947
First Author: Long AB
Year: 2013
Journal: Cell Death Differ
Title: Apaf1 apoptotic function critically limits Sonic hedgehog signaling during craniofacial development.
Volume: 20
Issue: 11
Pages: 1510-20
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Publication
9753320 | J:49840
First Author: Cecconi F
Year: 1998
Journal: Cell
Title: Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
Volume: 94
Issue: 6
Pages: 727-37
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Publication
24412373 | J:207987
 
First Author: Sancho M
Year: 2014
Journal: Neuroscience
Title: Inactivation of Apaf1 reduces the formation of mutant huntingtin-dependent aggregates and cell death.
Volume: 262
Pages: 83-91
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Publication
20966962 | J:186325
First Author: De Zio D
Year: 2011
Journal: Cell Death Differ
Title: The DNA repair complex Ku70/86 modulates Apaf1 expression upon DNA damage.
Volume: 18
Issue: 3
Pages: 516-27
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Publication
29596528 | J:261070
First Author: Tong H
Year: 2018
Journal: PLoS One
Title: Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells.
Volume: 13
Issue: 3
Pages: e0195119
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Publication
16086359 | J:100240
First Author: Müller M
Year: 2005
Journal: Dev Dyn
Title: Localization of Apaf1 gene expression in the early development of the mouse by means of in situ reverse transcriptase-polymerase chain reaction.
Volume: 234
Issue: 1
Pages: 215-21
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Publication
15262985 | J:93353
First Author: Cho DH
Year: 2004
Journal: J Biol Chem
Title: Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting protein.
Volume: 279
Issue: 38
Pages: 39942-50
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Publication
19914347 | J:164823
First Author: Shiraishi H
Year: 2010
Journal: Biochim Biophys Acta
Title: Alternative cell death of Apaf1-deficient neural progenitor cells induced by withdrawal of EGF or insulin.
Volume: 1800
Issue: 3
Pages: 405-15
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Publication
11279485 | J:68434
First Author: Joza N
Year: 2001
Journal: Nature
Title: Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death.
Volume: 410
Issue: 6828
Pages: 549-54
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Publication
10508592 | J:114162
First Author: Chautan M
Year: 1999
Journal: Curr Biol
Title: Interdigital cell death can occur through a necrotic and caspase-independent pathway.
Volume: 9
Issue: 17
Pages: 967-70
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Publication
11859117 | J:74772
First Author: Hara H
Year: 2002
Journal: J Immunol
Title: The apoptotic protease-activating factor 1-mediated pathway of apoptosis is dispensable for negative selection of thymocytes.
Volume: 168
Issue: 5
Pages: 2288-95
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Publication
16294213 | J:121038
First Author: Okamoto H
Year: 2006
Journal: Cell Death Differ
Title: Histological analyses of normally grown, fertile Apaf1-deficient mice.
Volume: 13
Issue: 4
Pages: 668-71
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Publication
12351193 | J:79525
First Author: Lüers GH
Year: 2002
Journal: Mech Dev
Title: Murine calmodulin binding protein 1 (Calmbp1): tissue-specific expression during development and in adult tissues.
Volume: 118
Issue: 1-2
Pages: 229-32
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Publication
9216040 | J:41353
First Author: Harris BS
Year: 1997
Journal: Teratology
Title: Forebrain overgrowth (fog): a new mutation in the mouse affecting neural tube development.
Volume: 55
Issue: 4
Pages: 231-40
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Publication
11504943 | J:71086
First Author: Honarpour N
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Apaf-1 deficiency and neural tube closure defects are found in fog mice.
Volume: 98
Issue: 17
Pages: 9683-7
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Publication
15907471 | J:98949
First Author: Hao Z
Year: 2005
Journal: Cell
Title: Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis.
Volume: 121
Issue: 4
Pages: 579-91
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Publication
10656767 | J:60409
First Author: Honarpour N
Year: 2000
Journal: Dev Biol
Title: Adult Apaf-1-deficient mice exhibit male infertility.
Volume: 218
Issue: 2
Pages: 248-58
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Publication
22162136 | J:178905
First Author: Yamaguchi Y
Year: 2011
Journal: J Cell Biol
Title: Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closure.
Volume: 195
Issue: 6
Pages: 1047-60
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Publication
11067867 | J:115112
First Author: Thompson LF
Year: 2000
Journal: J Clin Invest
Title: Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures.
Volume: 106
Issue: 9
Pages: 1149-57
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Publication
25827332 | J:324540
First Author: Armstrong PA
Year: 2015
Journal: Exp Brain Res
Title: Preserved otolith organ function in caspase-3-deficient mice with impaired horizontal semicircular canal function.
Volume: 233
Issue: 6
Pages: 1825-35
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Publication
23197294 | J:205616
First Author: Imao T
Year: 2013
Journal: Cell Death Differ
Title: Apaf-1- and Caspase-8-independent apoptosis.
Volume: 20
Issue: 2
Pages: 343-52
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Publication
32979334 | J:297668
First Author: Matsumoto Y
Year: 2020
Journal: Dev Biol
Title: Apoptosis is involved in maintaining the character of the midbrain and the diencephalon roof plate after neural tube closure.
Volume: 468
Issue: 1-2
Pages: 101-109
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Publication
17562856 | J:125016
First Author: Ho AT
Year: 2007
Journal: Mol Cell Biol
Title: XIAP activity dictates Apaf-1 dependency for caspase 9 activation.
Volume: 27
Issue: 16
Pages: 5673-85
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Publication
19960021 | J:186378
First Author: Nagasaka A
Year: 2010
Journal: Cell Death Differ
Title: Apaf-1-independent programmed cell death in mouse development.
Volume: 17
Issue: 6
Pages: 931-41
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Publication
16670300 | J:131709
First Author: Van De Wiele CJ
Year: 2006
Journal: J Immunol
Title: Further differentiation of murine double-positive thymocytes is inhibited in adenosine deaminase-deficient murine fetal thymic organ culture.
Volume: 176
Issue: 10
Pages: 5925-33
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Publication
15861188 | J:111864
First Author: Lindenboim L
Year: 2005
Journal: Cell Death Differ
Title: Bak but not Bax is essential for Bcl-xS-induced apoptosis.
Volume: 12
Issue: 7
Pages: 713-23
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Publication
15776018 | J:97306
First Author: Ruiz-Vela A
Year: 2005
Journal: EMBO Rep
Title: Proapoptotic BAX and BAK control multiple initiator caspases.
Volume: 6
Issue: 4
Pages: 379-85
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Publication
18483489 | J:154276
First Author: Ohsawa S
Year: 2008
Journal: Cell Death Differ
Title: Caspase-mediated changes in histone H1 in early apoptosis: prolonged caspase activation in developing olfactory sensory neurons.
Volume: 15
Issue: 9
Pages: 1429-39
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Publication
29068314 | J:258121
   
First Author: Fogel JL
Year: 2017
Journal: Elife
Title: A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations.
Volume: 6
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Publication
24416260 | J:211944
First Author: Sancho M
Year: 2014
Journal: PLoS One
Title: Altered mitochondria morphology and cell metabolism in Apaf1-deficient cells.
Volume: 9
Issue: 1
Pages: e84666
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Publication
20624980 | J:162564
First Author: Ohsawa S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.
Volume: 107
Issue: 30
Pages: 13366-71
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Publication
24369835 | J:206578
First Author: Nonomura K
Year: 2013
Journal: Dev Cell
Title: Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells.
Volume: 27
Issue: 6
Pages: 621-34
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Publication
20720205 | J:163541
First Author: Teague JE
Year: 2010
Journal: J Immunol
Title: Proximal events in 7,12-dimethylbenz[a]anthracene-induced, stromal cell-dependent bone marrow B cell apoptosis: stromal cell-B cell communication and apoptosis signaling.
Volume: 185
Issue: 6
Pages: 3369-78
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Publication
25525875 | J:219206
First Author: Rongvaux A
Year: 2014
Journal: Cell
Title: Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Volume: 159
Issue: 7
Pages: 1563-77
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Publication
25349173 | J:220780
First Author: Lu EP
Year: 2014
Journal: Blood
Title: Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice.
Volume: 124
Issue: 26
Pages: 3887-95
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Publication
19139631 | J:234766
First Author: Herrera VL
Year: 2009
Journal: Autophagy
Title: Autophagy: insights from DEspR-deficiency and haploinsufficiency.
Volume: 5
Issue: 2
Pages: 259-62
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Publication
19420217 | J:148528
First Author: Massa V
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Apoptosis is not required for mammalian neural tube closure.
Volume: 106
Issue: 20
Pages: 8233-8
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Gene
295961 | Apip
Type: gene
Organism: rat
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Gene
475943 | APIP
Type: gene
Organism: dog, domestic
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Gene
451118 | APIP
Type: gene
Organism: chimpanzee
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Gene
508345 | APIP
Type: gene
Organism: cattle
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Gene
428860 | APIP
Type: gene
Organism: chicken
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Gene
447941 | apip
Type: gene
Organism: zebrafish
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Gene
717291 | APIP
Type: gene
Organism: macaque, rhesus
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Gene
548429 | apip
Type: gene
Organism: frog, western clawed
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Publication
18256270 | J:131954
First Author: Oppenheim RW
Year: 2008
Journal: J Neurosci
Title: Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy.
Volume: 28
Issue: 6
Pages: 1490-7
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Publication
18497877 | J:137728
First Author: Hisatomi T
Year: 2008
Journal: J Clin Invest
Title: HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice.
Volume: 118
Issue: 6
Pages: 2025-38
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Publication
11731416 | J:73154
First Author: Guo Z
Year: 2001
Journal: Cancer Res
Title: Inactivation of the retinoblastoma tumor suppressor induces apoptosis protease-activating factor-1 dependent and independent apoptotic pathways during embryogenesis.
Volume: 61
Issue: 23
Pages: 8395-400
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Publication
19913007 | J:157262
First Author: Ioannides AS
Year: 2010
Journal: Dev Biol
Title: Foregut separation and tracheo-oesophageal malformations: the role of tracheal outgrowth, dorso-ventral patterning and programmed cell death.
Volume: 337
Issue: 2
Pages: 351-62
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Publication
15105372 | J:89365
First Author: Cecconi F
Year: 2004
Journal: Development
Title: Apaf1-dependent programmed cell death is required for inner ear morphogenesis and growth.
Volume: 131
Issue: 9
Pages: 2125-35
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Publication
15257302 | J:133362
First Author: Cozzolino M
Year: 2004
Journal: Cell Death Differ
Title: Apoptosome inactivation rescues proneural and neural cells from neurodegeneration.
Volume: 11
Issue: 11
Pages: 1179-91
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Publication
25975226 | J:317793
First Author: De Zio D
Year: 2015
Journal: Cell Mol Life Sci
Title: Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth.
Volume: 72
Issue: 21
Pages: 4173-91
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Publication
24632563 | J:210320
 
First Author: Josefsson EC
Year: 2014
Journal: Nat Commun
Title: Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.
Volume: 5
Pages: 3455
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Publication
27001308 | J:236189
First Author: Chinnam M
Year: 2016
Journal: Mol Cell Biol
Title: Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice.
Volume: 36
Issue: 11
Pages: 1621-7
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Publication
16465443 | J:108542
First Author: Wikenheiser-Brokamp KA
Year: 2006
Journal: Cell Mol Life Sci
Title: Retinoblastoma family proteins: insights gained through genetic manipulation of mice.
Volume: 63
Issue: 7-8
Pages: 767-80
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Publication
15843406 | J:98518
First Author: Mantela J
Year: 2005
Journal: Development
Title: The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.
Volume: 132
Issue: 10
Pages: 2377-88
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Protein Coding Gene
MGP_CAROLIEiJ_G0015723 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017642 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017621 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017584 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017407 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1306796 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018041 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016972 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017376 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017556 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017505 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018078 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016753 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031362 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016541 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
18562310 | J:141771
First Author: Sanchez-Olea R
Year: 2008
Journal: J Biol Chem
Title: Parcs is a dual regulator of cell proliferation and apaf-1 function.
Volume: 283
Issue: 36
Pages: 24400-5
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Publication
- | J:179045
     
First Author: He Z
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2012/01/09
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Publication
12121437 | J:133855
First Author: Matsuki Y
Year: 2002
Journal: Scand J Immunol
Title: Different role of Apaf-1 in positive selection, negative selection and death by neglect in foetal thymic organ culture.
Volume: 56
Issue: 2
Pages: 174-84
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Publication
18272486 | J:132183
First Author: Lin ML
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Selective suicide of cross-presenting CD8+ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset.
Volume: 105
Issue: 8
Pages: 3029-34
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Publication
16317003 | J:107485
First Author: Di Sano F
Year: 2006
Journal: J Biol Chem
Title: Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism.
Volume: 281
Issue: 5
Pages: 2693-700
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Publication
10342853 | J:55144
First Author: Robles R
Year: 1999
Journal: Endocrinology
Title: Localization, regulation and possible consequences of apoptotic protease-activating factor-1 (Apaf-1) expression in granulosa cells of the mouse ovary.
Volume: 140
Issue: 6
Pages: 2641-4
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Publication
12147675 | J:78264
First Author: Cregan SP
Year: 2002
Journal: J Cell Biol
Title: Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death.
Volume: 158
Issue: 3
Pages: 507-17
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Publication
18093951 | J:129271
First Author: Johnson CE
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
Volume: 104
Issue: 52
Pages: 20820-5
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Publication
22226830 | J:312806
First Author: Feng R
Year: 2012
Journal: Free Radic Biol Med
Title: Apaf-1 deficiency confers resistance to ultraviolet-induced apoptosis in mouse embryonic fibroblasts by disrupting reactive oxygen species amplification production and mitochondrial pathway.
Volume: 52
Issue: 5
Pages: 889-97
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GXD Expression
GXD Expression
     
Probe: MGI:3771192
Assay Type: Western blot
Annotation Date: 2008-02-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610526
Stage: TS26
Assay Id: MGI:3771199
Age: embryonic day 19.0
Specimen Label: E wt
Detected: true
Specimen Num: 1
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom