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Search results 1 to 86 out of 86 for Apba3

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
9546 | APBA3
Type: gene
Organism: human
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Gene
100495034 | apba3
Type: gene
Organism: frog, western clawed
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Gene
83611 | Apba3
Type: gene
Organism: rat
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Gene
485053 | APBA3
Type: gene
Organism: dog, domestic
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Gene
736073 | APBA3
Type: gene
Organism: chimpanzee
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Gene
511925 | APBA3
Type: gene
Organism: cattle
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Gene
420069 | APBA3
Type: gene
Organism: chicken
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Gene
713752 | APBA3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1888527 | Apba3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030531 | Apba3
Type: Family
Description: Amyloid beta A4 precursor protein-binding family A member 3, also known as Mint3, X11gamma, or X11L2, is a adaptor protein that enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of FIH-1 (factor inhibiting HIF-1). It may be a potential therapeutic target to regulate macrophage-mediated inflammation []. X11gamma regulates the traffic of the Alzheimer's precursor protein (APP) from the trans-Golgi network [].The X11/Mint family members are multidomain proteins typically composed of a conserved PTB domain and two C-terminal PDZ domains. They are adaptor proteins that possess several functions, such as trafficking and transport, synaptic function and regulation of ion channel []. Two of the family members, X11alpha and X11beta, are expressed primarily in neurones [].
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Protein
O88888
Organism: Mus musculus/domesticus
Length: 571  
Fragment?: false
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Protein
A0A1W2P6Z9
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: true
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Protein
A0A1W2P7G9
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
Q3TER1
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
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Protein
A0A1W2P837
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
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Protein
Q8BNM8
Organism: Mus musculus/domesticus
Length: 562  
Fragment?: false
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Protein
A0A1W2P6S0
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Publication
16764936 | -
First Author: Rogelj B
Year: 2006
Journal: Brain Res Rev
Title: The X11/Mint family of adaptor proteins.
Volume: 52
Issue: 2
Pages: 305-15
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Publication
19726677 | -
First Author: Sakamoto T
Year: 2009
Journal: J Biol Chem
Title: Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1.
Volume: 284
Issue: 44
Pages: 30350-9
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Publication
17959829 | -
First Author: Shrivastava-Ranjan P
Year: 2008
Journal: Mol Biol Cell
Title: Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.
Volume: 19
Issue: 1
Pages: 51-64
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Publication
21778228 | J:176742
First Author: Hara T
Year: 2011
Journal: J Biol Chem
Title: Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock.
Volume: 286
Issue: 37
Pages: 32542-51
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Publication
21893028 | J:177526
First Author: Hara T
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Genetic dissection of proteolytic and non-proteolytic contributions of MT1-MMP to macrophage invasion.
Volume: 413
Issue: 2
Pages: 277-81
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Publication
28507122 | J:242286
First Author: Hara T
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.
Volume: 114
Issue: 22
Pages: E4416-E4424
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Protein Coding Gene
MGP_CAROLIEiJ_G0015630 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017487 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1888527 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017941 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016877 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017388 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017459 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017982 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016658 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031043 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016448 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
28634075 | J:250868
First Author: Hara T
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Mint3 in bone marrow-derived cells promotes lung metastasis in breast cancer model mice.
Volume: 490
Issue: 3
Pages: 688-692
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Publication
27698125 | J:238492
First Author: Huai W
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Mint3 potentiates TLR3/4- and RIG-I-induced IFN-β expression and antiviral immune responses.
Volume: 113
Issue: 42
Pages: 11925-11930
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Publication
14990567 | J:212810
First Author: Wang P
Year: 2004
Journal: J Biol Chem
Title: Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV.
Volume: 279
Issue: 19
Pages: 20461-70
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Publication
19118172 | J:142874
First Author: Ho A
Year: 2008
Journal: J Neurosci
Title: Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease.
Volume: 28
Issue: 53
Pages: 14392-400
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Publication
9822620 | J:62652
First Author: Borg JP
Year: 1998
Journal: J Biol Chem
Title: Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting.
Volume: 273
Issue: 48
Pages: 31633-6
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Publication
17167098 | J:115573
First Author: Ho A
Year: 2006
Journal: J Neurosci
Title: Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family.
Volume: 26
Issue: 50
Pages: 13089-101
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Publication
30988517 | J:278658
First Author: Lin AY
Year: 2019
Journal: Sci Rep
Title: A rare autism-associated MINT2/APBA2 mutation disrupts neurexin trafficking and synaptic function.
Volume: 9
Issue: 1
Pages: 6024
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Publication
24742670 | J:215945
First Author: Sullivan SE
Year: 2014
Journal: J Biol Chem
Title: Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation.
Volume: 289
Issue: 22
Pages: 15374-83
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Apba3<em1Smoc> | MGI:7288282
Name: amyloid beta precursor protein binding family A member 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428171 | C57BL/6JSmoc-Apba3<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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