|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 86 out of 86 for Apba3

0.038s

Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
9546 | APBA3
Type: gene
Organism: human
•
•
•
•
•
Gene
100495034 | apba3
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
83611 | Apba3
Type: gene
Organism: rat
•
•
•
•
•
Gene
485053 | APBA3
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
736073 | APBA3
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
511925 | APBA3
Type: gene
Organism: cattle
•
•
•
•
•
Gene
420069 | APBA3
Type: gene
Organism: chicken
•
•
•
•
•
Gene
713752 | APBA3
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Coding Gene
MGI:1888527 | Apba3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Domain
IPR030531 | Apba3
Type: Family
Description: Amyloid beta A4 precursor protein-binding family A member 3, also known as Mint3, X11gamma, or X11L2, is a adaptor protein that enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of FIH-1 (factor inhibiting HIF-1). It may be a potential therapeutic target to regulate macrophage-mediated inflammation []. X11gamma regulates the traffic of the Alzheimer's precursor protein (APP) from the trans-Golgi network [].The X11/Mint family members are multidomain proteins typically composed of a conserved PTB domain and two C-terminal PDZ domains. They are adaptor proteins that possess several functions, such as trafficking and transport, synaptic function and regulation of ion channel []. Two of the family members, X11alpha and X11beta, are expressed primarily in neurones [].
•
•
•
•
•
Protein
O88888
Organism: Mus musculus/domesticus
Length: 571  
Fragment?: false
•
•
•
•
•
Protein
A0A1W2P6Z9
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: true
•
•
•
•
•
Protein
A0A1W2P7G9
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
•
•
•
•
•
Protein
Q3TER1
Organism: Mus musculus/domesticus
Length: 421  
Fragment?: false
•
•
•
•
•
Protein
A0A1W2P837
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
•
•
•
•
•
Protein
Q8BNM8
Organism: Mus musculus/domesticus
Length: 562  
Fragment?: false
•
•
•
•
•
Protein
A0A1W2P6S0
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
•
•
•
•
•
Publication
16764936 | -
First Author: Rogelj B
Year: 2006
Journal: Brain Res Rev
Title: The X11/Mint family of adaptor proteins.
Volume: 52
Issue: 2
Pages: 305-15
•
•
•
•
•
Publication
19726677 | -
First Author: Sakamoto T
Year: 2009
Journal: J Biol Chem
Title: Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1.
Volume: 284
Issue: 44
Pages: 30350-9
•
•
•
•
•
Publication
17959829 | -
First Author: Shrivastava-Ranjan P
Year: 2008
Journal: Mol Biol Cell
Title: Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.
Volume: 19
Issue: 1
Pages: 51-64
•
•
•
•
•
Publication
21778228 | J:176742
First Author: Hara T
Year: 2011
Journal: J Biol Chem
Title: Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock.
Volume: 286
Issue: 37
Pages: 32542-51
•
•
•
•
•
Publication
21893028 | J:177526
First Author: Hara T
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Genetic dissection of proteolytic and non-proteolytic contributions of MT1-MMP to macrophage invasion.
Volume: 413
Issue: 2
Pages: 277-81
•
•
•
•
•
Publication
28507122 | J:242286
First Author: Hara T
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes.
Volume: 114
Issue: 22
Pages: E4416-E4424
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0015630 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0017547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0017525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0017486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0017487 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0017310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1888527 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0017941 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0016877 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0017282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0017388 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0017382 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0017459 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0017408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0017982 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0016658 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0016937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0031043 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0016448 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
28634075 | J:250868
First Author: Hara T
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Mint3 in bone marrow-derived cells promotes lung metastasis in breast cancer model mice.
Volume: 490
Issue: 3
Pages: 688-692
•
•
•
•
•
Publication
27698125 | J:238492
First Author: Huai W
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Mint3 potentiates TLR3/4- and RIG-I-induced IFN-β expression and antiviral immune responses.
Volume: 113
Issue: 42
Pages: 11925-11930
•
•
•
•
•
Publication
14990567 | J:212810
First Author: Wang P
Year: 2004
Journal: J Biol Chem
Title: Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV.
Volume: 279
Issue: 19
Pages: 20461-70
•
•
•
•
•
Publication
19118172 | J:142874
First Author: Ho A
Year: 2008
Journal: J Neurosci
Title: Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease.
Volume: 28
Issue: 53
Pages: 14392-400
•
•
•
•
•
Publication
9822620 | J:62652
First Author: Borg JP
Year: 1998
Journal: J Biol Chem
Title: Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting.
Volume: 273
Issue: 48
Pages: 31633-6
•
•
•
•
•
Publication
17167098 | J:115573
First Author: Ho A
Year: 2006
Journal: J Neurosci
Title: Genetic analysis of Mint/X11 proteins: essential presynaptic functions of a neuronal adaptor protein family.
Volume: 26
Issue: 50
Pages: 13089-101
•
•
•
•
•
Publication
30988517 | J:278658
First Author: Lin AY
Year: 2019
Journal: Sci Rep
Title: A rare autism-associated MINT2/APBA2 mutation disrupts neurexin trafficking and synaptic function.
Volume: 9
Issue: 1
Pages: 6024
•
•
•
•
•
Publication
24742670 | J:215945
First Author: Sullivan SE
Year: 2014
Journal: J Biol Chem
Title: Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid β generation.
Volume: 289
Issue: 22
Pages: 15374-83
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
•
•
•
•
•
Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Allele
Apba3<em1Smoc> | MGI:7288282
Name: amyloid beta precursor protein binding family A member 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:6428171 | C57BL/6JSmoc-Apba3<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom