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Search results 1 to 94 out of 94 for Aplf

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Hits by Category

Hits by Strain

Type Details Score
Gene
200558 | APLF
Type: gene
Organism: human
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Gene
100127823 | aplf
Type: gene
Organism: frog, western clawed
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Gene
500247 | Aplf
Type: gene
Organism: rat
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Gene
481405 | APLF
Type: gene
Organism: dog, domestic
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Gene
459293 | APLF
Type: gene
Organism: chimpanzee
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Gene
507989 | APLF
Type: gene
Organism: cattle
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Gene
421264 | APLF
Type: gene
Organism: chicken
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Gene
705875 | APLF
Type: gene
Organism: macaque, rhesus
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Gene
101884102 | aplf
Type: gene
Organism: zebrafish
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Protein Domain
IPR039253 | APLF
Type: Family
Description: The protein APLF (aprataxin and PNK-like factor or Xip1; ) is a nuclease involved in single-strand and double-strand DNA break repair []. It has endo- and exonuclease activities and contains a FHA (forkhead-associated) domain and zinc-finger-like CYR motifs []. APLF interacts with XRCC1 and XRCC4 via its FHA domain [, ].
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Protein Coding Gene
MGI:1919353 | Aplf
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9D842
Organism: Mus musculus/domesticus
Length: 499  
Fragment?: false
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Publication
27875275 | J:247123
First Author: Syed KM
Year: 2016
Journal: J Cell Sci
Title: Histone chaperone APLF regulates induction of pluripotency in murine fibroblasts.
Volume: 129
Issue: 24
Pages: 4576-4591
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Publication
18077224 | -
First Author: Macrae CJ
Year: 2008
Journal: DNA Repair (Amst)
Title: APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation.
Volume: 7
Issue: 2
Pages: 292-302
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Publication
21211721 | J:168260
First Author: Rulten SL
Year: 2011
Journal: Mol Cell
Title: PARP-3 and APLF function together to accelerate nonhomologous end-joining.
Volume: 41
Issue: 1
Pages: 33-45
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Publication
33277378 | J:311886
 
First Author: Varghese PC
Year: 2021
Journal: J Cell Sci
Title: Histone chaperone APLF level dictates the implantation of mouse embryos.
Volume: 134
Issue: 1
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Publication
17353262 | -
First Author: Iles N
Year: 2007
Journal: Mol Cell Biol
Title: APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks.
Volume: 27
Issue: 10
Pages: 3793-803
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Publication
17507382 | -
First Author: Bekker-Jensen S
Year: 2007
Journal: J Biol Chem
Title: Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks.
Volume: 282
Issue: 27
Pages: 19638-43
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Publication
17396150 | -
First Author: Kanno S
Year: 2007
Journal: EMBO J
Title: A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses.
Volume: 26
Issue: 8
Pages: 2094-103
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Protein
Q8BVD9
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: false
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Publication
27711078 | J:339876
First Author: Tong KI
Year: 2016
Journal: Cell Death Dis
Title: Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model.
Volume: 7
Issue: 10
Pages: e2401
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Protein Coding Gene
MGP_CAROLIEiJ_G0028615 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030995 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030892 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030736 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1919353 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031431 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030083 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030658 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030814 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030767 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030891 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030800 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031458 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029798 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022352 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029626 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:6885835
Assay Type: RT-PCR
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:6885859
Age: embryonic day 2.0
Specimen Label: 4-cell
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6885835
Assay Type: RT-PCR
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Stage: TS03
Assay Id: MGI:6885859
Age: embryonic day 2.5
Specimen Label: 8-cell
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6885835
Assay Type: RT-PCR
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Stage: TS04
Assay Id: MGI:6885859
Age: embryonic day 3.0
Specimen Label: morula
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6885835
Assay Type: RT-PCR
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Stage: TS04
Assay Id: MGI:6885859
Age: embryonic day 3.5
Specimen Label: blastocyst
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:6885855
Age: embryonic day 2.0
Note: Expressed within the nucleus, as well as in the cytosol.
Specimen Label: 1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Not Specified
Stage: TS03
Assay Id: MGI:6885855
Age: embryonic day 2.0
Note: Expressed within the nucleus, as well as in the cytosol.
Specimen Label: S1A
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1605911
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6885855
Age: embryonic day 7.5
Specimen Label: 2F/H/I
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187711
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6885855
Age: embryonic day 7.5
Specimen Label: 2F/H/I
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.5
Note: Significantly downregulated expression. A significant level of expression was enhanced within the trophectoderm.
Specimen Label: 1C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.5
Specimen Label: S1C
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.5
Note: Significantly downregulated expression. A significant level of expression was enhanced within the trophectoderm.
Specimen Label: S1D
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.5
Note: Significantly downregulated expression. A significant level of expression was enhanced within the trophectoderm.
Specimen Label: 1E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.0
Note: Enhanced expression.
Specimen Label: 1B upper
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.0
Note: Enhanced expression.
Specimen Label: 1B lower
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160404
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.0
Note: Enhanced expression.
Specimen Label: S1B
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610711
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6885855
Age: embryonic day 7.5
Specimen Label: 2F/H/I
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.5
Specimen Label: 1C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.5
Specimen Label: S1D
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160464
Pattern: Not Specified
Stage: TS04
Assay Id: MGI:6885855
Age: embryonic day 3.5
Specimen Label: 1E
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6885839
Assay Type: Immunohistochemistry
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604611
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:6885855
Age: embryonic day 7.5
Specimen Label: 2F/H/I
Detected: true
Specimen Num: 6
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Publication
17277741 | J:118199
 
First Author: Danciger M
Year: 2007
Journal: Mol Vis
Title: Quantitative genetics of age-related retinal degeneration: a second F1 intercross between the A/J and C57BL/6 strains.
Volume: 13
Pages: 79-85
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q9D842-2
Organism: Mus musculus/domesticus
Length: 391  
Fragment?: false
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Protein
Q9D842-3
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Publication
20098424 | -
First Author: Eustermann S
Year: 2010
Journal: Nat Struct Mol Biol
Title: Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).
Volume: 17
Issue: 2
Pages: 241-3
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Protein Domain
IPR019406 | APLF_PBZ
Type: Domain
Description: The PBZ (PAR-binding zinc-finger) domain is a zinc-finger motif that can be found in humans APLF (aprataxin- and PNK-like forkhead association domain-containing protein) [, ]. The Znf is highly conserved both in primary sequence and in the spacing between the putative zinc coordinating residues and is configured CX5CX6HX5H. Many of the proteins containing the APLF-like Znf are involved in DNA strand break repair and/or contain domains implicated in DNA metabolism [].
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Publication
30104678 | J:266496
First Author: Chen Q
Year: 2018
Journal: Nat Commun
Title: PARP2 mediates branched poly ADP-ribosylation in response to DNA damage.
Volume: 9
Issue: 1
Pages: 3233
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Publication
18172500 | -
First Author: Ahel I
Year: 2008
Journal: Nature
Title: Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins.
Volume: 451
Issue: 7174
Pages: 81-5
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Protein
Q810L3
Organism: Mus musculus/domesticus
Length: 664  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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