Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
rabbit, European |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
pig, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:980046 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-01-15 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1750322 |
|
Stage: |
TS22 |
Assay Id: |
MGI:3826009 |
Age: |
embryonic day 14.5 |
Image: |
Additional file 4 Apoa1 |
|
Specimen Label: |
Additional file 4 Apoa1 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Berisha SZ |
Year: |
2015 |
Journal: |
J Lipid Res |
Title: |
HDL from apoA1 transgenic mice expressing the 4WF isoform is resistant to oxidative loss of function. |
Volume: |
56 |
Issue: |
3 |
Pages: |
653-664 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boisvert WA |
Year: |
1999 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
ApoA1 reduces free cholesterol accumulation in atherosclerotic lesions of ApoE-deficient mice transplanted with ApoE-expressing macrophages. |
Volume: |
19 |
Issue: |
3 |
Pages: |
525-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stoye NM |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Alzheimer's disease in the gut-Major changes in the gut of 5xFAD model mice with ApoA1 as potential key player. |
Volume: |
34 |
Issue: |
9 |
Pages: |
11883-11899 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miller RD |
Year: |
1989 |
Journal: |
Immunogenetics |
Title: |
Genetic mapping of mouse T3d and T3e between Apoa1 and Ncam. |
Volume: |
30 |
Issue: |
6 |
Pages: |
511-4 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
198
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wiltshire SA |
Year: |
2012 |
Journal: |
Physiol Genomics |
Title: |
Genetic control of high density lipoprotein-cholesterol in AcB/BcA recombinant congenic strains of mice. |
Volume: |
44 |
Issue: |
17 |
Pages: |
843-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chiesa G |
Year: |
1992 |
Journal: |
J Biol Chem |
Title: |
Reconstitution of lipoprotein(a) by infusion of human low density lipoprotein into transgenic mice expressing human apolipoprotein(a). |
Volume: |
267 |
Issue: |
34 |
Pages: |
24369-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lawn RM |
Year: |
1996 |
Journal: |
J Biol Chem |
Title: |
Feedback mechanism of focal vascular lesion formation in transgenic apolipoprotein(a) mice. |
Volume: |
271 |
Issue: |
49 |
Pages: |
31367-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Parolini C |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Targeted replacement of mouse apolipoprotein A-I with human ApoA-I or the mutant ApoA-IMilano. Evidence of APOA-IM impaired hepatic secretion. |
Volume: |
278 |
Issue: |
7 |
Pages: |
4740-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ariel M |
Year: |
1994 |
Journal: |
Nat Genet |
Title: |
Developmental changes in methylation of spermatogenesis-specific genes include reprogramming in the epididymis. |
Volume: |
7 |
Issue: |
1 |
Pages: |
59-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
She M |
Year: |
1999 |
Journal: |
Clin Exp Pharmacol Physiol |
Title: |
Inhibition of intimal lipid deposition in human apolipoprotein A1 transgenic mice. |
Volume: |
26 |
Issue: |
10 |
Pages: |
833-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li H |
Year: |
1993 |
Journal: |
Arterioscler Thromb |
Title: |
Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice. |
Volume: |
13 |
Issue: |
12 |
Pages: |
1814-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zamanian-Daryoush M |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects. |
Volume: |
288 |
Issue: |
29 |
Pages: |
21237-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dadabayev AR |
Year: |
2014 |
Journal: |
J Nutr |
Title: |
Apolipoprotein A1 regulates coenzyme Q10 absorption, mitochondrial function, and infarct size in a mouse model of myocardial infarction. |
Volume: |
144 |
Issue: |
7 |
Pages: |
1030-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hajri T |
Year: |
1998 |
Journal: |
Biochim Biophys Acta |
Title: |
The acute phase response in apolipoprotein A-1 knockout mice: apolipoprotein serum amyloid A and lipid distribution in plasma high density lipoproteins. |
Volume: |
1394 |
Issue: |
2-3 |
Pages: |
209-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsujita M |
Year: |
2021 |
Journal: |
FEBS Lett |
Title: |
Apolipoprotein A-I in mouse cerebrospinal fluid derives from the liver and intestine via plasma high-density lipoproteins assembled by ABCA1 and LCAT. |
Volume: |
595 |
Issue: |
6 |
Pages: |
773-788 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kluck GEG |
Year: |
2023 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Apolipoprotein A1 Protects Against Necrotic Core Development in Atherosclerotic Plaques: PDZK1-Dependent High-Density Lipoprotein Suppression of Necroptosis in Macrophages. |
Volume: |
43 |
Issue: |
1 |
Pages: |
45-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xepapadaki E |
Year: |
2019 |
Journal: |
Biochim Biophys Acta Mol Basis Dis |
Title: |
Impact of apolipoprotein A1- or lecithin:cholesterol acyltransferase-deficiency on white adipose tissue metabolic activity and glucose homeostasis in mice. |
Volume: |
1865 |
Issue: |
6 |
Pages: |
1351-1360 |
|
•
•
•
•
•
|
Publication |
First Author: |
Button EB |
Year: |
2019 |
Journal: |
Alzheimers Res Ther |
Title: |
ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice. |
Volume: |
11 |
Issue: |
1 |
Pages: |
44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang Y |
Year: |
2014 |
Journal: |
Nat Med |
Title: |
An abundant dysfunctional apolipoprotein A1 in human atheroma. |
Volume: |
20 |
Issue: |
2 |
Pages: |
193-203 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gulshan K |
Year: |
2016 |
Journal: |
Circ Res |
Title: |
PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly. |
Volume: |
119 |
Issue: |
7 |
Pages: |
827-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xepapadaki E |
Year: |
2021 |
Journal: |
Biochim Biophys Acta Mol Cell Biol Lipids |
Title: |
Tissue-specific functional interaction between apolipoproteins A1 and E in cold-induced adipose organ mitochondrial energy metabolism. |
Volume: |
1866 |
Issue: |
3 |
Pages: |
158859 |
|
•
•
•
•
•
|
Publication |
First Author: |
Durham KK |
Year: |
2018 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner. |
Volume: |
314 |
Issue: |
1 |
Pages: |
H31-H44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nargis T |
Year: |
2023 |
Journal: |
Biochim Biophys Acta Mol Cell Biol Lipids |
Title: |
Characterization of lipoproteins in human placenta and fetal circulation as well as gestational changes in lipoprotein assembly and secretion in human and mouse placentas. |
Volume: |
1868 |
Issue: |
9 |
Pages: |
159357 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fitz NF |
Year: |
2015 |
Journal: |
Brain |
Title: |
Opposing effects of Apoe/Apoa1 double deletion on amyloid-β pathology and cognitive performance in APP mice. |
Volume: |
138 |
Issue: |
Pt 12 |
Pages: |
3699-715 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kassa FA |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Absence of apolipoprotein E protects mice from cerebral malaria. |
Volume: |
6 |
|
Pages: |
33615 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Stoffel W |
Year: |
1992 |
Journal: |
Biol Chem Hoppe Seyler |
Title: |
Mouse apolipoprotein AI. cDNA-derived primary structure, gene organisation and complete nucleotide sequence. |
Volume: |
373 |
Issue: |
4 |
Pages: |
187-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Williamson R |
Year: |
1992 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I. |
Volume: |
89 |
Issue: |
15 |
Pages: |
7134-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hughes SD |
Year: |
1997 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
HDL deficiency in genetically engineered mice requires elevated LDL to accelerate atherogenesis. |
Volume: |
17 |
Issue: |
9 |
Pages: |
1725-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang ZY |
Year: |
2024 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Apolipoprotein A-1 Accelerated Liver Regeneration Through Regulating Autophagy Via AMPK-ULK1 Pathway. |
Volume: |
17 |
Issue: |
4 |
Pages: |
539-551 |
|
•
•
•
•
•
|
Publication |
First Author: |
Spady DK |
Year: |
1998 |
Journal: |
J Lipid Res |
Title: |
Kinetic characteristics and regulation of HDL cholesteryl ester and apolipoprotein transport in the apoA-I-/- mouse. |
Volume: |
39 |
Issue: |
7 |
Pages: |
1483-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Button EB |
Year: |
2021 |
Journal: |
Alzheimers Res Ther |
Title: |
Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury. |
Volume: |
13 |
Issue: |
1 |
Pages: |
58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jolley CD |
Year: |
2000 |
Journal: |
Hepatology |
Title: |
Induction of bile acid synthesis by cholesterol and cholestyramine feeding is unimpaired in mice deficient in apolipoprotein AI. |
Volume: |
32 |
Issue: |
6 |
Pages: |
1309-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zamanian-Daryoush M |
Year: |
2020 |
Journal: |
Oncotarget |
Title: |
Apolipoprotein A-I anti-tumor activity targets cancer cell metabolism. |
Volume: |
11 |
Issue: |
19 |
Pages: |
1777-1796 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iqbal J |
Year: |
2005 |
Journal: |
J Lipid Res |
Title: |
Evidence for multiple complementary pathways for efficient cholesterol absorption in mice. |
Volume: |
46 |
Issue: |
7 |
Pages: |
1491-501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sorci-Thomas MG |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Single repeat deletion in ApoA-I blocks cholesterol esterification and results in rapid catabolism of delta6 and wild-type ApoA-I in transgenic mice. |
Volume: |
275 |
Issue: |
16 |
Pages: |
12156-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dai C |
Year: |
2012 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Apolipoprotein A-I attenuates ovalbumin-induced neutrophilic airway inflammation via a granulocyte colony-stimulating factor-dependent mechanism. |
Volume: |
47 |
Issue: |
2 |
Pages: |
186-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2010 |
Journal: |
J Lipid Res |
Title: |
Genetic deletion of apolipoprotein A-I increases airway hyperresponsiveness, inflammation, and collagen deposition in the lung. |
Volume: |
51 |
Issue: |
9 |
Pages: |
2560-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chiesa G |
Year: |
1998 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Human apolipoproteins A-I and A-II in cell cholesterol efflux: studies with transgenic mice. |
Volume: |
18 |
Issue: |
9 |
Pages: |
1417-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fagan AM |
Year: |
2004 |
Journal: |
Am J Pathol |
Title: |
ApoAI deficiency results in marked reductions in plasma cholesterol but no alterations in amyloid-beta pathology in a mouse model of Alzheimer's disease-like cerebral amyloidosis. |
Volume: |
165 |
Issue: |
4 |
Pages: |
1413-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cabana VG |
Year: |
1999 |
Journal: |
J Lipid Res |
Title: |
SAA-only HDL formed during the acute phase response in apoA-I+/+ and apoA-I-/- mice. |
Volume: |
40 |
Issue: |
6 |
Pages: |
1090-103 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rebholz SL |
Year: |
2018 |
Journal: |
FASEB J |
Title: |
Studies in genetically modified mice implicate maternal HDL as a mediator of fetal growth. |
Volume: |
32 |
Issue: |
2 |
Pages: |
717-727 |
|
•
•
•
•
•
|
Publication |
First Author: |
Götz A |
Year: |
2018 |
Journal: |
J Lipid Res |
Title: |
Circulating HDL levels control hypothalamic astrogliosis via apoA-I. |
Volume: |
59 |
Issue: |
9 |
Pages: |
1649-1659 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki M |
Year: |
2010 |
Journal: |
Circulation |
Title: |
High-density lipoprotein suppresses the type I interferon response, a family of potent antiviral immunoregulators, in macrophages challenged with lipopolysaccharide. |
Volume: |
122 |
Issue: |
19 |
Pages: |
1919-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zamanian-Daryoush M |
Year: |
2020 |
Journal: |
J Biol Chem |
Title: |
Site-specific 5-hydroxytryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high-density lipoprotein biogenesis. |
Volume: |
295 |
Issue: |
15 |
Pages: |
4836-4848 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo L |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
High density lipoprotein protects against polymicrobe-induced sepsis in mice. |
Volume: |
288 |
Issue: |
25 |
Pages: |
17947-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dalakoura-Karagkouni K |
Year: |
2022 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Using adenovirus-mediated gene transfer to study the effect of myeloperoxidase on plasma lipid levels, HDL structure and functionality in mice expressing human apoA-I forms. |
Volume: |
622 |
|
Pages: |
108-114 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao X |
Year: |
2024 |
Journal: |
J Immunol |
Title: |
Neutrophil Heterogeneity Is Modified during Acute Lung Inflammation in Apoa1-/- Mice. |
Volume: |
213 |
Issue: |
4 |
Pages: |
456-468 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stein O |
Year: |
1997 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Delayed loss of cholesterol from a localized lipoprotein depot in apolipoprotein A-I-deficient mice. |
Volume: |
94 |
Issue: |
18 |
Pages: |
9820-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rubin EM |
Year: |
1991 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses. |
Volume: |
88 |
Issue: |
2 |
Pages: |
434-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tietge UJ |
Year: |
2002 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Human secretory phospholipase A2 mediates decreased plasma levels of HDL cholesterol and apoA-I in response to inflammation in human apoA-I transgenic mice. |
Volume: |
22 |
Issue: |
7 |
Pages: |
1213-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ossoli A |
Year: |
2016 |
Journal: |
Biochem J |
Title: |
Plasma-derived and synthetic high-density lipoprotein inhibit tissue factor in endothelial cells and monocytes. |
Volume: |
473 |
Issue: |
2 |
Pages: |
211-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chennamsetty I |
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