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Search results 1 to 100 out of 155 for Appl1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein
Organism: Mus musculus
Length: 236  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Hupalowska A
Year: 2012
Journal: J Cell Sci
Title: APPL1 regulates basal NF-κB activity by stabilizing NIK.
Volume: 125
Issue: Pt 17
Pages: 4090-102
Publication
First Author: Park M
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: APPL1 transgenic mice are protected from high-fat diet-induced cardiac dysfunction.
Volume: 305
Issue: 7
Pages: E795-804
Publication
First Author: Ryu J
Year: 2014
Journal: Cell Rep
Title: APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor.
Volume: 7
Issue: 4
Pages: 1227-38
Publication
First Author: Xin X
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway.
Volume: 300
Issue: 1
Pages: E103-10
Publication
First Author: Mao X
Year: 2006
Journal: Nat Cell Biol
Title: APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function.
Volume: 8
Issue: 5
Pages: 516-23
Publication
First Author: Galan-Davila AK
Year: 2018
Journal: J Biol Chem
Title: Alternative splicing variant of the scaffold protein APPL1 suppresses hepatic adiponectin signaling and function.
Volume: 293
Issue: 16
Pages: 6064-6074
Publication
First Author: Cheng KK
Year: 2009
Journal: Cell Metab
Title: APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice.
Volume: 9
Issue: 5
Pages: 417-27
Publication
First Author: Tan Y
Year: 2010
Journal: Genesis
Title: Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.
Volume: 48
Issue: 9
Pages: 531-9
Publication
First Author: Yeo JC
Year: 2016
Journal: Traffic
Title: Distinct Roles for APPL1 and APPL2 in Regulating Toll-like Receptor 4 Signaling in Macrophages.
Volume: 17
Issue: 9
Pages: 1014-26
Publication
First Author: Cheng KK
Year: 2013
Journal: Biochem J
Title: TRAF6-mediated ubiquitination of APPL1 enhances hepatic actions of insulin by promoting the membrane translocation of Akt.
Volume: 455
Issue: 2
Pages: 207-16
Publication
First Author: Wang YB
Year: 2012
Journal: J Neurosci
Title: Adaptor protein APPL1 couples synaptic NMDA receptor with neuronal prosurvival phosphatidylinositol 3-kinase/Akt pathway.
Volume: 32
Issue: 35
Pages: 11919-29
Publication
First Author: Jiang X
Year: 2017
Journal: Diabetologia
Title: APPL1 prevents pancreatic beta cell death and inflammation by dampening NFκB activation in a mouse model of type 1 diabetes.
Volume: 60
Issue: 3
Pages: 464-474
Publication
First Author: Wang C
Year: 2013
Journal: Diabetologia
Title: Deficiency of APPL1 in mice impairs glucose-stimulated insulin secretion through inhibition of pancreatic beta cell mitochondrial function.
Volume: 56
Issue: 9
Pages: 1999-2009
Publication
First Author: Cheng KK
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: APPL1 potentiates insulin secretion in pancreatic β cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in mice.
Volume: 109
Issue: 23
Pages: 8919-24
Publication
First Author: Tan Y
Year: 2010
Journal: J Biol Chem
Title: Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.
Volume: 285
Issue: 9
Pages: 6377-89
Publication
First Author: Wang Y
Year: 2011
Journal: Diabetes
Title: APPL1 counteracts obesity-induced vascular insulin resistance and endothelial dysfunction by modulating the endothelial production of nitric oxide and endothelin-1 in mice.
Volume: 60
Issue: 11
Pages: 3044-54
Publication
First Author: Tan Y
Year: 2016
Journal: J Cell Physiol
Title: Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts.
Volume: 231
Issue: 5
Pages: 1142-50
Publication
First Author: Wang C
Year: 2009
Journal: J Biol Chem
Title: Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells.
Volume: 284
Issue: 46
Pages: 31608-15
Publication  
First Author: Ding Y
Year: 2016
Journal: Mol Cell Endocrinol
Title: APPL1-mediated activation of STAT3 contributes to inhibitory effect of adiponectin on hepatic gluconeogenesis.
Volume: 433
Pages: 12-9
Publication
First Author: Mao L
Year: 2014
Journal: Cell Biosci
Title: Absence of Appl2 sensitizes endotoxin shock through activation of PI3K/Akt pathway.
Volume: 4
Issue: 1
Pages: 60
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:6369401
Assay Type: RT-PCR
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674828
Stage: TS28
Assay Id: MGI:6369402
Age: postnatal
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6369401
Assay Type: RT-PCR
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674828
Stage: TS28
Assay Id: MGI:6369402
Age: postnatal
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6369401
Assay Type: RT-PCR
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1674828
Stage: TS28
Assay Id: MGI:6369402
Age: postnatal
Image: 1
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6369401
Assay Type: RT-PCR
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1674828
Stage: TS28
Assay Id: MGI:6369402
Age: postnatal
Image: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6369365
Assay Type: RT-PCR
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1674828
Stage: TS28
Assay Id: MGI:6369388
Age: postnatal
Image: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6369365
Assay Type: RT-PCR
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674828
Stage: TS28
Assay Id: MGI:6369388
Age: postnatal
Image: 1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6369365
Assay Type: RT-PCR
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674828
Stage: TS28
Assay Id: MGI:6369388
Age: postnatal
Image: 1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6369365
Assay Type: RT-PCR
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1674828
Stage: TS28
Assay Id: MGI:6369388
Age: postnatal
Image: 1
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 12
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271528
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: false
Specimen Num: 14
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: false
Specimen Num: 12
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 15
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 14
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 18
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6369448
Age: embryonic day 18.5
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 21
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 20
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 24
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 23
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:6369367
Assay Type: Western blot
Annotation Date: 2019-11-04
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6369404
Age: postnatal adult
Image: 2
Detected: true
Specimen Num: 7
Publication
First Author: Tu Q
Year: 2011
Journal: J Biol Chem
Title: Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1.
Volume: 286
Issue: 14
Pages: 12542-53
Publication
First Author: Yeo JC
Year: 2015
Journal: Mol Biol Cell
Title: Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages.
Volume: 26
Issue: 5
Pages: 952-65
Publication
First Author: Fu X
Year: 2011
Journal: Mol Biol Cell
Title: Retrolinkin cooperates with endophilin A1 to mediate BDNF-TrkB early endocytic trafficking and signaling from early endosomes.
Volume: 22
Issue: 19
Pages: 3684-98
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90