Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Data Source |
|
•
•
•
•
•
|
Strain |
Attribute String: |
outbred stock, strain family |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The Activity-Regulated Cytoskeleton-associated protein (Arc), also referred to as Arg3.1 (Activity-Regulated Gene), is an immediate-early gene predominantly found in mammals that has been related to synaptic plasticity, learning and memory processes [, , , , ]. It has been shown that Arc/Arg3.1 expression increases with strong synaptic activation []. Its mRNA is transported to activated dendritic regions, conferring on the protein-distribution temporal correlation with the inducing stimulus and spatial specificity [, ].Via interactions with dynamin and endophilin isoforms, the Arc/Arg3.1 protein enhances receptor endocytosis []. Specifically, it modulates trafficking of neuronal AMPA-type glutamate receptors (AMPARs) by accelerating endocytosis and reducing surface expression []. In particular, Arc/Arg3.1 has been shown to reduce the number of GluR2/3 receptors, leading to a decrease in AMPAR-mediated synaptic currents []. These observations are consistent with a role in homeostatic regulation of synaptic strength [, ]. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang W |
Year: |
2019 |
Journal: |
Mol Cell |
Title: |
Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation. |
Volume: |
75 |
Issue: |
1 |
Pages: |
13-25.e5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1380553 |
Assay Type: |
RNA in situ |
Annotation Date: |
2009-01-15 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:2622022 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:3825926 |
Age: |
embryonic day 14.5 |
Image: |
Additional file 4 Arc |
|
Specimen Label: |
Additional file 4 Arc |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Greer PL |
Year: |
2010 |
Journal: |
Cell |
Title: |
The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. |
Volume: |
140 |
Issue: |
5 |
Pages: |
704-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shepherd JD |
Year: |
2006 |
Journal: |
Neuron |
Title: |
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors. |
Volume: |
52 |
Issue: |
3 |
Pages: |
475-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chowdhury S |
Year: |
2006 |
Journal: |
Neuron |
Title: |
Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking. |
Volume: |
52 |
Issue: |
3 |
Pages: |
445-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
de la Peña JB |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Intercellular Arc Signaling Regulates Vasodilation. |
Volume: |
41 |
Issue: |
37 |
Pages: |
7712-7726 |
|
•
•
•
•
•
|
Publication |
First Author: |
Epstein I |
Year: |
2018 |
Journal: |
Semin Cell Dev Biol |
Title: |
The Arc of cognition: Signaling cascades regulating Arc and implications for cognitive function and disease. |
Volume: |
77 |
|
Pages: |
63-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wall MJ |
Year: |
2018 |
Journal: |
Neuron |
Title: |
The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility. |
Volume: |
98 |
Issue: |
6 |
Pages: |
1124-1132.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren M |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Arc regulates experience-dependent persistent firing patterns in frontal cortex. |
Volume: |
34 |
Issue: |
19 |
Pages: |
6583-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peebles CL |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Arc regulates spine morphology and maintains network stability in vivo. |
Volume: |
107 |
Issue: |
42 |
Pages: |
18173-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jenks KR |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Arc restores juvenile plasticity in adult mouse visual cortex. |
Volume: |
114 |
Issue: |
34 |
Pages: |
9182-9187 |
|
•
•
•
•
•
|
Genotype |
|
Background: |
ARC |
Zygosity: |
ot |
Has Mutant Allele: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Chowhury S |
Year: |
1999 |
Journal: |
GenBank Submission |
Title: |
Mus musculus growth factor ARC (Arc) mRNA, complete cds |
|
|
Pages: |
AF162777 |
|
•
•
•
•
•
|
Publication |
First Author: |
Korb E |
Year: |
2013 |
Journal: |
Nat Neurosci |
Title: |
Arc in the nucleus regulates PML-dependent GluA1 transcription and homeostatic plasticity. |
Volume: |
16 |
Issue: |
7 |
Pages: |
874-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lalonde J |
Year: |
2017 |
Journal: |
Nat Commun |
Title: |
Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability. |
Volume: |
8 |
Issue: |
1 |
Pages: |
1659 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
396
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kyrke-Smith M |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
The Immediate Early Gene Arc Is Not Required for Hippocampal Long-Term Potentiation. |
Volume: |
41 |
Issue: |
19 |
Pages: |
4202-4211 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCurry CL |
Year: |
2010 |
Journal: |
Nat Neurosci |
Title: |
Loss of Arc renders the visual cortex impervious to the effects of sensory experience or deprivation. |
Volume: |
13 |
Issue: |
4 |
Pages: |
450-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rudinskiy N |
Year: |
2012 |
Journal: |
Nat Neurosci |
Title: |
Orchestrated experience-driven Arc responses are disrupted in a mouse model of Alzheimer's disease. |
Volume: |
15 |
Issue: |
10 |
Pages: |
1422-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang KH |
Year: |
2006 |
Journal: |
Cell |
Title: |
In vivo two-photon imaging reveals a role of arc in enhancing orientation specificity in visual cortex. |
Volume: |
126 |
Issue: |
2 |
Pages: |
389-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pastuzyn ED |
Year: |
2018 |
Journal: |
Cell |
Title: |
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. |
Volume: |
172 |
Issue: |
1-2 |
Pages: |
275-288.e18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ravens A |
Year: |
2023 |
Journal: |
iScience |
Title: |
Arc regulates a second-guessing cognitive bias during naturalistic foraging through effects on discrete behavior modules. |
Volume: |
26 |
Issue: |
5 |
Pages: |
106761 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fernández E |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence. |
Volume: |
21 |
Issue: |
3 |
Pages: |
679-691 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li L |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors. |
Volume: |
25 |
Issue: |
23 |
Pages: |
10286-300 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rial Verde EM |
Year: |
2006 |
Journal: |
Neuron |
Title: |
Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission. |
Volume: |
52 |
Issue: |
3 |
Pages: |
461-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bock J |
Year: |
2005 |
Journal: |
Neuroscience |
Title: |
Early socio-emotional experience induces expression of the immediate-early gene Arc/arg3.1 (activity-regulated cytoskeleton-associated protein/activity-regulated gene) in learning-relevant brain regions of the newborn chick. |
Volume: |
133 |
Issue: |
3 |
Pages: |
625-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKimpson WM |
Year: |
2021 |
Journal: |
Dev Cell |
Title: |
Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes. |
Volume: |
56 |
Issue: |
6 |
Pages: |
747-760.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mandel-Brehm C |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Seizure-like activity in a juvenile Angelman syndrome mouse model is attenuated by reducing Arc expression. |
Volume: |
112 |
Issue: |
16 |
Pages: |
5129-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pyo JO |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice. |
Volume: |
283 |
Issue: |
45 |
Pages: |
30707-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
McKimpson WM |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes. |
Volume: |
7 |
Issue: |
1 |
Pages: |
7019 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith-Hicks C |
Year: |
2010 |
Journal: |
Nat Neurosci |
Title: |
SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells. |
Volume: |
13 |
Issue: |
9 |
Pages: |
1082-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maier B |
Year: |
2003 |
Journal: |
Biol Reprod |
Title: |
Developmental association of the synaptic activity-regulated protein arc with the mouse acrosomal organelle and the sperm tail. |
Volume: |
68 |
Issue: |
1 |
Pages: |
67-76 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6189801 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Arc |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6189801 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Arc |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6189801 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Arc |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6189801 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Arc |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189801 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Arc |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189801 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Arc |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6167624 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6189801 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Arc |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Niere F |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression. |
Volume: |
32 |
Issue: |
17 |
Pages: |
5924-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Itoh M |
Year: |
2019 |
Journal: |
Neuropsychopharmacol Rep |
Title: |
Perturbed expression pattern of the immediate early gene Arc in the dentate gyrus of GluA1 C-terminal palmitoylation-deficient mice. |
Volume: |
39 |
Issue: |
1 |
Pages: |
61-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie L |
Year: |
2013 |
Journal: |
J Neurochem |
Title: |
Early life stress-induced histone acetylations correlate with activation of the synaptic plasticity genes Arc and Egr1 in the mouse hippocampus. |
Volume: |
125 |
Issue: |
3 |
Pages: |
457-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qiu J |
Year: |
2016 |
Journal: |
J Neuroendocrinol |
Title: |
Decreased Npas4 and Arc mRNA Levels in the Hippocampus of Aged Memory-Impaired Wild-Type But Not Memory Preserved 11β-HSD1 Deficient Mice. |
Volume: |
28 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pastuzyn ED |
Year: |
2017 |
Journal: |
Front Mol Neurosci |
Title: |
Activity-Dependent Arc Expression and Homeostatic Synaptic Plasticity Are Altered in Neurons from a Mouse Model of Angelman Syndrome. |
Volume: |
10 |
|
Pages: |
234 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang H |
Year: |
2016 |
Journal: |
J Neurosci |
Title: |
Metabotropic Glutamate Receptors Induce a Form of LTP Controlled by Translation and Arc Signaling in the Hippocampus. |
Volume: |
36 |
Issue: |
5 |
Pages: |
1723-9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6766425 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-10-12 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3514228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6766558 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
ARC |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki A |
Year: |
2020 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Loss of Arc attenuates the behavioral and molecular responses for sleep homeostasis in mice. |
Volume: |
117 |
Issue: |
19 |
Pages: |
10547-10553 |
|
•
•
•
•
•
|
Allele |
Name: |
arco piccolo |
Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okuno H |
Year: |
2012 |
Journal: |
Cell |
Title: |
Inverse synaptic tagging of inactive synapses via dynamic interaction of Arc/Arg3.1 with CaMKIIβ. |
Volume: |
149 |
Issue: |
4 |
Pages: |
886-98 |
|
•
•
•
•
•
|
Allele |
Name: |
vacuolar protein sorting 33B; targeted mutation 1.1, TaconicArtemis |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog; targeted mutation 1c, Mouse Biology Program, UC Davis |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Guenthner CJ |
Year: |
2013 |
Journal: |
Neuron |
Title: |
Permanent genetic access to transiently active neurons via TRAP: targeted recombination in active populations. |
Volume: |
78 |
Issue: |
5 |
Pages: |
773-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castello-Waldow TP |
Year: |
2020 |
Journal: |
PLoS Biol |
Title: |
Hippocampal neurons with stable excitatory connectivity become part of neuronal representations. |
Volume: |
18 |
Issue: |
11 |
Pages: |
e3000928 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zuk KE |
Year: |
2023 |
Journal: |
J Neurosci |
Title: |
Arc-Expressing Accessory Olfactory Bulb Interneurons Support Chemosensory Social Behavioral Plasticity. |
Volume: |
43 |
Issue: |
7 |
Pages: |
1178-1190 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cho HY |
Year: |
2021 |
Journal: |
Curr Biol |
Title: |
Turnover of fear engram cells by repeated experience. |
Volume: |
31 |
Issue: |
24 |
Pages: |
5450-5461.e4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka DH |
Year: |
2019 |
Journal: |
Neuroscience |
Title: |
Genetic Access to Gustatory Disgust-Associated Neurons in the Interstitial Nucleus of the Posterior Limb of the Anterior Commissure in Male Mice. |
Volume: |
413 |
|
Pages: |
45-63 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Mikuni T |
Year: |
2013 |
Journal: |
Neuron |
Title: |
Arc/Arg3.1 is a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum. |
Volume: |
78 |
Issue: |
6 |
Pages: |
1024-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Managò F |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia. |
Volume: |
16 |
Issue: |
8 |
Pages: |
2116-2128 |
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Publication |
First Author: |
Cao VY |
Year: |
2015 |
Journal: |
Neuron |
Title: |
Motor Learning Consolidates Arc-Expressing Neuronal Ensembles in Secondary Motor Cortex. |
Volume: |
86 |
Issue: |
6 |
Pages: |
1385-92 |
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Publication |
First Author: |
Jenks KR |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Experience-Dependent Development and Maintenance of Binocular Neurons in the Mouse Visual Cortex. |
Volume: |
30 |
Issue: |
6 |
Pages: |
1982-1994.e4 |
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Publication |
First Author: |
Nakayama D |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
Long-delayed expression of the immediate early gene Arc/Arg3.1 refines neuronal circuits to perpetuate fear memory. |
Volume: |
35 |
Issue: |
2 |
Pages: |
819-30 |
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Publication |
First Author: |
Dirven BCJ |
Year: |
2024 |
Journal: |
Neuroscience |
Title: |
Hippocampal Trauma Memory Processing Conveying Susceptibility to Traumatic Stress. |
Volume: |
540 |
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Pages: |
87-102 |
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Publication |
First Author: |
Epp JR |
Year: |
2015 |
Journal: |
eNeuro |
Title: |
Optimization of CLARITY for Clearing Whole-Brain and Other Intact Organs(1,2,3). |
Volume: |
2 |
Issue: |
3 |
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Publication |
First Author: |
Guskjolen A |
Year: |
2018 |
Journal: |
Curr Biol |
Title: |
Recovery of "Lost" Infant Memories in Mice. |
Volume: |
28 |
Issue: |
14 |
Pages: |
2283-2290.e3 |
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Publication |
First Author: |
Xie X |
Year: |
2023 |
Journal: |
STAR Protoc |
Title: |
Activity-dependent labeling and manipulation of fentanyl-recruited striatal ensembles using ArcTRAP approach. |
Volume: |
4 |
Issue: |
3 |
Pages: |
102369 |
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Publication |
First Author: |
Wegenast-Braun BM |
Year: |
2009 |
Journal: |
Am J Pathol |
Title: |
Independent effects of intra- and extracellular Abeta on learning-related gene expression. |
Volume: |
175 |
Issue: |
1 |
Pages: |
271-82 |
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Publication |
First Author: |
Penrod RD |
Year: |
2019 |
Journal: |
Genes Brain Behav |
Title: |
Activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) regulates anxiety- and novelty-related behaviors. |
Volume: |
18 |
Issue: |
7 |
Pages: |
e12561 |
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Publication |
First Author: |
Barylko B |
Year: |
2018 |
Journal: |
Biochemistry |
Title: |
Palmitoylation and Membrane Binding of Arc/Arg3.1: A Potential Role in Synaptic Depression. |
Volume: |
57 |
Issue: |
5 |
Pages: |
520-524 |
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Publication |
First Author: |
Gao M |
Year: |
2010 |
Journal: |
J Neurosci |
Title: |
A specific requirement of Arc/Arg3.1 for visual experience-induced homeostatic synaptic plasticity in mouse primary visual cortex. |
Volume: |
30 |
Issue: |
21 |
Pages: |
7168-78 |
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Publication |
First Author: |
Templin AT |
Year: |
2017 |
Journal: |
Diabetes |
Title: |
Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation. |
Volume: |
66 |
Issue: |
10 |
Pages: |
2636-2645 |
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Publication |
First Author: |
Byers CE |
Year: |
2015 |
Journal: |
Biochim Biophys Acta |
Title: |
Enhancement of dynamin polymerization and GTPase activity by Arc/Arg3.1. |
Volume: |
1850 |
Issue: |
6 |
Pages: |
1310-8 |
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Publication |
First Author: |
Zhang MD |
Year: |
2018 |
Journal: |
J Clin Invest |
Title: |
Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity. |
Volume: |
128 |
Issue: |
9 |
Pages: |
3757-3768 |
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Publication |
First Author: |
Perusini JN |
Year: |
2017 |
Journal: |
Hippocampus |
Title: |
Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer's disease mice. |
Volume: |
27 |
Issue: |
10 |
Pages: |
1110-1122 |
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Publication |
First Author: |
Hunsberger HC |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Divergence in the metabolome between natural aging and Alzheimer's disease. |
Volume: |
10 |
Issue: |
1 |
Pages: |
12171 |
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Publication |
First Author: |
Liu D |
Year: |
2000 |
Journal: |
Mech Dev |
Title: |
Activity-regulated, cytoskeleton-associated protein (Arc) is essential for visceral endoderm organization during early embryogenesis. |
Volume: |
92 |
Issue: |
2 |
Pages: |
207-15 |
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Publication |
First Author: |
Mabb AM |
Year: |
2014 |
Journal: |
Neuron |
Title: |
Triad3A regulates synaptic strength by ubiquitination of Arc. |
Volume: |
82 |
Issue: |
6 |
Pages: |
1299-316 |
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Publication |
First Author: |
Chen JY |
Year: |
2018 |
Journal: |
Neuron |
Title: |
Parabrachial CGRP Neurons Establish and Sustain Aversive Taste Memories. |
Volume: |
100 |
Issue: |
4 |
Pages: |
891-899.e5 |
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Publication |
First Author: |
Chang CW |
Year: |
2017 |
Journal: |
Elife |
Title: |
Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D. |
Volume: |
6 |
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Publication |
First Author: |
Ishii KK |
Year: |
2017 |
Journal: |
Neuron |
Title: |
A Labeled-Line Neural Circuit for Pheromone-Mediated Sexual Behaviors in Mice. |
Volume: |
95 |
Issue: |
1 |
Pages: |
123-137.e8 |
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Publication |
First Author: |
Hagihara KM |
Year: |
2021 |
Journal: |
Nature |
Title: |
Intercalated amygdala clusters orchestrate a switch in fear state. |
Volume: |
594 |
Issue: |
7863 |
Pages: |
403-407 |
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Publication |
First Author: |
Wu J |
Year: |
2011 |
Journal: |
Cell |
Title: |
Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation. |
Volume: |
147 |
Issue: |
3 |
Pages: |
615-28 |
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Publication |
First Author: |
Sams DS |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Neuronal CTCF Is Necessary for Basal and Experience-Dependent Gene Regulation, Memory Formation, and Genomic Structure of BDNF and Arc. |
Volume: |
17 |
Issue: |
9 |
Pages: |
2418-2430 |
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Publication |
First Author: |
Mastwal S |
Year: |
2023 |
Journal: |
Elife |
Title: |
Adolescent neurostimulation of dopamine circuit reverses genetic deficits in frontal cortex function. |
Volume: |
12 |
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Publication |
First Author: |
Cansler HL |
Year: |
2017 |
Journal: |
J Neurosci |
Title: |
Experience-Dependent Plasticity in Accessory Olfactory Bulb Interneurons following Male-Male Social Interaction. |
Volume: |
37 |
Issue: |
30 |
Pages: |
7240-7252 |
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Genotype |
Symbol: |
Vps33b/Vps33b Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> |
Background: |
involves: C57BL/6 * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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