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Search results 1 to 100 out of 104 for Arhgap6

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
395 | ARHGAP6
Type: gene
Organism: human
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Gene
100127692 | arhgap6
Type: gene
Organism: frog, western clawed
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Gene
491738 | ARHGAP6
Type: gene
Organism: dog, domestic
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Gene
473518 | ARHGAP6
Type: gene
Organism: chimpanzee
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Gene
100140016 | ARHGAP6
Type: gene
Organism: cattle
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Gene
100363276 | Arhgap6
Type: gene
Organism: rat
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Gene
418642 | ARHGAP6
Type: gene
Organism: chicken
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Gene
709978 | ARHGAP6
Type: gene
Organism: macaque, rhesus
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Gene
101882360 | arhgap6
Type: gene
Organism: zebrafish
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Protein
A0A2X0U4H9
Organism: Mus musculus/domesticus
Length: 976  
Fragment?: true
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Protein Coding Gene
MGI:1196332 | Arhgap6
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10699171 | J:80946
First Author: Prakash SK
Year: 2000
Journal: Hum Mol Genet
Title: Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA.
Volume: 9
Issue: 4
Pages: 477-88
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Publication
9417914 | J:44720
First Author: Schaefer L
Year: 1997
Journal: Genomics
Title: Cloning and characterization of a novel rho-type GTPase-activating protein gene (ARHGAP6) from the critical region for microphthalmia with linear skin defects.
Volume: 46
Issue: 2
Pages: 268-77
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Publication
12444108 | J:80528
First Author: Prakash SK
Year: 2002
Journal: Hum Mol Genet
Title: Loss of holocytochrome c-type synthetase causes the male lethality of X-linked dominant microphthalmia with linear skin defects (MLS) syndrome.
Volume: 11
Issue: 25
Pages: 3237-48
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Protein Coding Gene
MGP_CAROLIEiJ_G0033582 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0036275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0036245 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0036174 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0036239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035946 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1196332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036762 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0035233 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0036086 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0036018 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0036171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0036050 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034932 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035369 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0032121 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034751 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7624400
Assay Type: RT-PCR
Annotation Date: 2024-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3551927
Stage: TS27
Assay Id: MGI:7624429
Age: postnatal newborn
Image: 6
Specimen Label: wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7624400
Assay Type: RT-PCR
Annotation Date: 2024-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3551927
Stage: TS27
Assay Id: MGI:7624429
Age: postnatal newborn
Image: 6
Specimen Label: Arhgap28 del
Detected: true
Specimen Num: 2
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Publication
25211221 | J:222518
First Author: Yeung CY
Year: 2014
Journal: PLoS One
Title: Arhgap28 is a RhoGAP that inactivates RhoA and downregulates stress fibers.
Volume: 9
Issue: 9
Pages: e107036
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Publication
9722948 | J:49564
First Author: Van den Veyver IB
Year: 1998
Journal: Genomics
Title: Characterization and physical mapping in human and mouse of a novel RING finger gene in Xp22.
Volume: 51
Issue: 2
Pages: 251-61
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Publication
11668396 | J:85267
First Author: Cormier TA
Year: 2001
Journal: Mamm Genome
Title: Analysis of Mid1, Hccs, Arhgap6, and Msl3l1 in X-linked polydactyly (Xpl) and Patchy-fur (Paf) mutant mice.
Volume: 12
Issue: 10
Pages: 796-8
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR041852 | ARHGAP6_RhoGAP
Type: Domain
Description: This entry represent the RhoGAP domain found in ARHGAP6 and ARHGAP36.Rho GTPase activating protein 6 (ARHGAP6/RHOGAP6) shows GAP activity towards RhoA, but not towards Cdc42 and Rac1 []. ARHGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS); MLS is a severe X-linked developmental disorder []. ARHGAP36 is a potent antagonist of PKAsignalling [].
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Publication
12900578 | -
First Author: Kutsche K
Year: 2002
Journal: Cytogenet Genome Res
Title: Microphthalmia with linear skin defects syndrome (MLS): a male with a mosaic paracentric inversion of Xp.
Volume: 99
Issue: 1-4
Pages: 297-302
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Publication
27713425 | -
 
First Author: Eccles RL
Year: 2016
Journal: Nat Commun
Title: Bimodal antagonism of PKA signalling by ARHGAP36.
Volume: 7
Pages: 12963
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Protein
Q3TPC4
Organism: Mus musculus/domesticus
Length: 321  
Fragment?: true
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Protein
Q3TGN4
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
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Protein
Q3TAR2
Organism: Mus musculus/domesticus
Length: 321  
Fragment?: true
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Publication
18434237 | -
First Author: Ochocka AM
Year: 2008
Journal: Int J Biochem Cell Biol
Title: Regulation of phospholipase C-delta1 by ARGHAP6, a GTPase-activating protein for RhoA: possible role for enhanced activity of phospholipase C in hypertension.
Volume: 40
Issue: 10
Pages: 2264-73
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Protein Domain
IPR030772 | RhoGAP6
Type: Family
Description: Rho GTPase-activating protein 6 (RhoGAP6, also known as ARHGAP6) is both a GTPase-activating protein (GAP) with specificity for RhoA and a cytoskeletal protein that promotes actinremodelling []. It binds to and upregulates phospholipase C-delta, indicating a role for ARHGAP6 in enhanced activity of phospholipase C in hypertension [].
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Protein Domain
IPR037863 | RHOGAP6/36
Type: Family
Description: Rho GTPase activating protein 6 (ArhGAP6/RHOGAP6) shows GAP activity towards RhoA, but not towards Cdc42 and Rac1 []. ArhGAP6 is often deleted in microphthalmia with linear skin defects syndrome (MLS); MLS is a severe X-linked developmental disorder [].This family also includes ARHGAP36, which is a potent antagonist of PKA signalling [].
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Allele
Arhgap6/Hccs/Mid1<tm1Hzo> | MGI:2447298
Name: midline 1; targeted mutation 1, Huda Y Zoghbi
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Arhgap6/Hccs/Mid1<tm1Hzo> | MGI:3580071
Name: Rho GTPase activating protein 6; targeted mutation 1, Huda Y Zoghbi
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Arhgap6/Hccs/Mid1<tm1Hzo> | MGI:3580072
Name: holocytochrome c synthetase; targeted mutation 1, Huda Y Zoghbi
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Arhgap6<tm1Hzo> | MGI:2447302
Name: Rho GTPase activating protein 6; targeted mutation 1, Huda Y Zoghbi
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Arhgap6/Hccs/Mid1
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/?
Background: involves: 129S7/SvEvBrd
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/?
Background: involves: 129S7/SvEvBrd
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/?
Background: involves: 129S7/SvEvBrd
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Arhgap6/Hccs/Mid1
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Arhgap6/Hccs/Mid1
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Protein
O54834
Organism: Mus musculus/domesticus
Length: 987  
Fragment?: false
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Protein
G3UZI7
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Genotype
Genotype
Symbol: Arhgap6/Arhgap6
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/? Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/? Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/? Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Arhgap6/Hccs/Mid1 Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Arhgap6/Hccs/Mid1 Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Arhgap6/Hccs/Mid1 Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Arhgap6<+> Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Hccs<+> Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arhgap6/Hccs/Mid1/Mid1<+> Tg(EIIa-cre)C5379Lmgd/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Protein
B1AUC7
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: false
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Protein
Z4YJK0
Organism: Mus musculus/domesticus
Length: 533  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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Cambridge CB2 3EH, United Kingdom