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Search results 1 to 85 out of 85 for Arhgef16

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
27237 | ARHGEF16
Type: gene
Organism: human
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Gene
549614 | arhgef16
Type: gene
Organism: frog, western clawed
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Gene
607691 | ARHGEF16
Type: gene
Organism: dog, domestic
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Gene
748158 | ARHGEF16
Type: gene
Organism: chimpanzee
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Gene
687105 | Arhgef16
Type: gene
Organism: rat
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Gene
514453 | ARHGEF16
Type: gene
Organism: cattle
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Gene
419386 | ARHGEF16
Type: gene
Organism: chicken
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Gene
567180 | arhgef16
Type: gene
Organism: zebrafish
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Gene
694808 | ARHGEF16
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2446219 | Arhgef16
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25063526 | J:218482
First Author: Lee J
Year: 2014
Journal: Biochim Biophys Acta
Title: Arhgef16, a novel Elmo1 binding partner, promotes clearance of apoptotic cells via RhoG-dependent Rac1 activation.
Volume: 1843
Issue: 11
Pages: 2438-47
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Protein Coding Gene
MGP_CAROLIEiJ_G0026871 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029195 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029160 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029108 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028897 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2446219 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029625 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028310 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029008 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028972 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029098 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028999 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029657 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028030 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029219 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027864 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611816
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:2683211
Age: embryonic day 9.5
Image: E9.5
Note: Epithelial expression extends from the ventral forebrain to the fourth branchial arch.
Specimen Label: E9.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1606911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:2683211
Age: embryonic day 7.5
Image: E7.5
Note: Expression detected in the headfold pocket.
Specimen Label: E7.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:160599
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:2683211
Age: embryonic day 6.5
Image: E6.5
Note: Strongly expressed in a single domain comprising the most proximal region of the egg cylinder and a proximo-distal stripe within the ectoplacental come.
Specimen Label: E6.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1605911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:2683211
Age: embryonic day 7.5
Image: E7.5
Note: Strongly expressed in a single domain comprising the most proximal region of the egg cylinder and a proximo-distal stripe within the ectoplacental come.
Specimen Label: E7.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1639916
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:2683211
Age: embryonic day 9.5
Image: E9.5
Note: Epithelial expression extends from the ventral forebrain to the fourth branchial arch.
Specimen Label: E9.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1605811
Pattern: Uniform
Stage: TS11
Assay Id: MGI:2683211
Age: embryonic day 7.5
Image: E7.5
Note: Expressed throughout visceral endoderm.
Specimen Label: E7.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:160399
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:2683211
Age: embryonic day 6.5
Image: E6.5
Note: Strongly expressed in a single domain comprising the most proximal region of the egg cylinder and a proximo-distal stripe within the ectoplacental come.
Specimen Label: E6.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Regionally restricted
Stage: TS11
Assay Id: MGI:2683211
Age: embryonic day 7.5
Image: E7.5
Note: Strongly expressed in a single domain comprising the most proximal region of the egg cylinder and a proximo-distal stripe within the ectoplacental come.
Specimen Label: E7.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1614413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:2683211
Age: embryonic day 8.5
Image: E8.5
Note: Strong expression detected in the ventral forebrain.
Specimen Label: E8.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1664016
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:2683211
Age: embryonic day 9.5
Image: E9.5
Note: Epithelial expression extends from the ventral forebrain to the fourth branchial arch.
Specimen Label: E9.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1624813
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:2683211
Age: embryonic day 8.5
Image: E8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1627216
Pattern: Regionally restricted
Stage: TS16
Assay Id: MGI:2683211
Age: embryonic day 9.5
Image: E9.5
Note: Epithelial expression extends from the ventral forebrain to the fourth branchial arch.
Specimen Label: E9.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666916
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:2683211
Age: embryonic day 9.5
Image: E9.5
Specimen Label: E9.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610111
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:2683211
Age: embryonic day 7.5
Image: E7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610211
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:2683211
Age: embryonic day 7.5
Image: E7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2683064
Assay Type: RNA in situ
Annotation Date: 2004-01-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1619113
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:2683211
Age: embryonic day 8.5
Image: E8.5
Specimen Label: E8.5
Detected: true
Specimen Num: 3
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Publication
7671812 | J:28008
First Author: Harrison SM
Year: 1995
Journal: Development
Title: Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.
Volume: 121
Issue: 8
Pages: 2479-89
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Publication
14613977 | J:85124
First Author: Sousa-Nunes R
Year: 2003
Journal: Genome Res
Title: Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.
Volume: 13
Issue: 12
Pages: 2609-20
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Arhgef16<em1Smoc> | MGI:7288335
Name: Rho guanine nucleotide exchange factor 16; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6474797 | C57BL/6JSmoc-Arhgef16<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
20679435 | -
First Author: Hiramoto-Yamaki N
Year: 2010
Journal: J Cell Biol
Title: Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism.
Volume: 190
Issue: 3
Pages: 461-77
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Publication
21621533 | -
First Author: Harada K
Year: 2011
Journal: Exp Cell Res
Title: Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase.
Volume: 317
Issue: 12
Pages: 1701-13
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Publication
15133129 | -
First Author: Ellerbroek SM
Year: 2004
Journal: Mol Biol Cell
Title: SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis.
Volume: 15
Issue: 7
Pages: 3309-19
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Protein Domain
IPR035797 | ARHGEF16/ARHGEF26_SH3
Type: Domain
Description: ARHGEF16, also called ephexin-4, acts as a guanine nucleotide exchange factor (GEF) for RhoG, activating it by exchanging bound GDP for free GTP. RhoG is a small GTPase that is a crucial regulator of Rac in migrating cells. ARHGEF16 interacts directly with the ephrin receptor EphA2 and mediates cell migration and invasion in breast cancer cells by activating RhoG [, ]. ARHGEF26, also called SGEF (SH3 domain-containing GEF), also activates RhoG. It is highly expressed in liver and may play a role in regulating membrane dynamics []. ARHGEF16 and ARHGEF26 contain RhoGEF (also called Dbl-homologous or DH), Pleckstrin Homology(PH), and SH3 domains. The SH3 domains of ARHGEFs play an autoinhibitory role through intramolecular interactions with a proline-rich region N-terminal to the DH domain. The SH3 domain of ARHGEF16 also binds to Elmo, and this interaction may relieve the self-inhibitory state ofARHGEF16 [].This entry represents the SH3 domains of ARHGEF16 and ARHGEF26.
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Protein
Q3U5C8
Organism: Mus musculus/domesticus
Length: 713  
Fragment?: false
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Protein
D3YYY8
Organism: Mus musculus/domesticus
Length: 869  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom