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Search results 1 to 100 out of 148 for Arhgef2

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0.065s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Ravindran E
Year: 2017
Journal: PLoS Genet
Title: Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation.
Volume: 13
Issue: 4
Pages: e1006746
Publication
First Author: Zhou P
Year: 2021
Journal: iScience
Title: Arhgef2 regulates neural differentiation in the cerebral cortex through mRNA m6A-methylation of Npdc1 and Cend1.
Volume: 24
Issue: 6
Pages: 102645
Publication
First Author: Chan DCH
Year: 2021
Journal: Blood Adv
Title: Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis.
Volume: 5
Issue: 16
Pages: 3120-3133
Publication
First Author: Gauthier-Fisher A
Year: 2009
Journal: Nat Neurosci
Title: Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells.
Volume: 12
Issue: 6
Pages: 735-44
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Whitehead I
Year: 1995
Journal: J Biol Chem
Title: Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C.
Volume: 270
Issue: 31
Pages: 18388-95
Publication
First Author: Meiri D
Year: 2012
Journal: Mol Cell
Title: Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition.
Volume: 45
Issue: 5
Pages: 642-55
Publication
First Author: Fine N
Year: 2016
Journal: J Cell Biol
Title: GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.
Volume: 215
Issue: 1
Pages: 107-119
Publication
First Author: Fine N
Year: 2020
Journal: J Immunol
Title: GEF-H1 Is Required for Colchicine Inhibition of Neutrophil Rolling and Recruitment in Mouse Models of Gout.
Volume: 205
Issue: 12
Pages: 3300-3310
Publication  
First Author: Kopf A
Year: 2020
Journal: J Cell Biol
Title: Microtubules control cellular shape and coherence in amoeboid migrating cells.
Volume: 219
Issue: 6
Publication
First Author: Heck JN
Year: 2012
Journal: Mol Biol Cell
Title: Microtubules regulate GEF-H1 in response to extracellular matrix stiffness.
Volume: 23
Issue: 13
Pages: 2583-92
GXD Expression    
Probe: MGI:3028567
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3028573
Age: embryonic day 13.0
Image: 2
Specimen Label: E13
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3028567
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:3028573
Age: embryonic day 17.0
Image: 2
Specimen Label: E17
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3028567
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028573
Age: postnatal day 7
Image: 2
Specimen Label: P7
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3028567
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3028573
Age: postnatal adult
Image: 2
Specimen Label: adult
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3028567
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3028573
Age: postnatal adult
Image: 2
Specimen Label: L
Specimen Num: 5
GXD Expression    
Probe: MGI:3028567
Assay Type: Northern blot
Annotation Date: 2004-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3028573
Age: postnatal adult
Image: 2
Specimen Label: T
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:3766131
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3766131
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:3766131
Age: embryonic day 19.0
Specimen Label: E19
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3766131
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3766131
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:3766131
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3766131
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3766131
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3766131
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3766131
Age: postnatal day 30
Specimen Label: P30
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3766065
Assay Type: Western blot
Annotation Date: 2008-01-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:3766131
Age: postnatal day 150
Specimen Label: P150
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:5695275
Assay Type: Western blot
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691018
Stage: TS18
Assay Id: MGI:5695286
Age: embryonic day 11.0
Image: 1
Specimen Label: E11
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5695275
Assay Type: Western blot
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691019
Stage: TS19
Assay Id: MGI:5695286
Age: embryonic day 11.5
Image: 1
Specimen Label: E11.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5695275
Assay Type: Western blot
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Stage: TS20
Assay Id: MGI:5695286
Age: embryonic day 12.0
Image: 1
Specimen Label: E12
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5695275
Assay Type: Western blot
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5695286
Age: embryonic day 15.0
Image: 1
Specimen Label: E15
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5695275
Assay Type: Western blot
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:5695286
Age: embryonic day 18.0
Image: 1
Specimen Label: E18
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5695275
Assay Type: Western blot
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:5695286
Age: postnatal day 2
Image: 1
Specimen Label: P2
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:3028567
Assay Type: RNA in situ
Annotation Date: 2004-02-25
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3028695
Age: embryonic day 14.5
Image: 4A
Specimen Label: 4A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3028567
Assay Type: RNA in situ
Annotation Date: 2004-02-25
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3028695
Age: embryonic day 14.5
Image: 4A
Specimen Label: 4A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3028567
Assay Type: RNA in situ
Annotation Date: 2004-02-25
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1666822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3028695
Age: embryonic day 14.5
Image: 4A
Specimen Label: 4A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3028567
Assay Type: RNA in situ
Annotation Date: 2004-02-25
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1603922
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3028695
Age: embryonic day 14.5
Image: 4A
Note: The authors state there is weak to moderate expression in several non-neural tissues.
Specimen Label: 4A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3028567
Assay Type: RNA in situ
Annotation Date: 2004-02-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Uniform
Stage: TS22
Assay Id: MGI:3028695
Age: embryonic day 14.5
Image: 4E
Specimen Label: 4E
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5695275
Assay Type: Immunohistochemistry
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5695294
Age: embryonic day 15.0
Image: 1b
Specimen Label: 1b
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5695275
Assay Type: Immunohistochemistry
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5695294
Age: embryonic day 15.0
Image: 1b
Specimen Label: 1b
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5695275
Assay Type: Immunohistochemistry
Annotation Date: 2015-11-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5695294
Age: embryonic day 15.0
Image: 1b
Specimen Label: 1b
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5925386
Assay Type: RNA in situ
Annotation Date: 2017-11-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691618
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:5925395
Age: embryonic day 11.0
Image: S5A
Note: Expressed in the neuroepithelium.
Specimen Label: S5A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5925386
Assay Type: RNA in situ
Annotation Date: 2017-11-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691018
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:5925395
Age: embryonic day 11.0
Image: S5A
Note: Expressed in the neuroepithelium.
Specimen Label: S5A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5925386
Assay Type: RNA in situ
Annotation Date: 2017-11-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689618
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:5925395
Age: embryonic day 11.0
Image: S5A
Note: Expressed in the neuroepithelium.
Specimen Label: S5A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5925386
Assay Type: RNA in situ
Annotation Date: 2017-11-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284227
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5925395
Age: postnatal day 0
Image: S5B left
Note: Expressed in the germinal zone.
Specimen Label: S5B left
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5925386
Assay Type: RNA in situ
Annotation Date: 2017-11-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5925395
Age: postnatal day 0
Image: S5B middle
Note: Expressed in the germinal zone.
Specimen Label: S5B middle
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5925386
Assay Type: RNA in situ
Annotation Date: 2017-11-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3569227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5925395
Age: postnatal day 0
Image: S5B right
Specimen Label: S5B right
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5925386
Assay Type: RNA in situ
Annotation Date: 2017-11-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3291718
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:5925398
Age: embryonic day 11.0
Image: S9
Note: Co-expressed largely with Barhl1-positive cells emanating from dA1 progenitors and throughout the anterior and posterior extramural streams precerebellar neurons.
Specimen Label: S9
Detected: true
Specimen Num: 1
Publication
First Author: Snyder JT
Year: 2002
Journal: Nat Struct Biol
Title: Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Volume: 9
Issue: 6
Pages: 468-75
Publication
First Author: Kosoff R
Year: 2013
Journal: J Biol Chem
Title: Pak2 kinase restrains mast cell FcεRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity.
Volume: 288
Issue: 2
Pages: 974-83
Publication
First Author: Guilluy C
Year: 2011
Journal: Nat Cell Biol
Title: The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.
Volume: 13
Issue: 6
Pages: 722-7
Publication
First Author: Sáez JJ
Year: 2019
Journal: J Cell Biol
Title: The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells.
Volume: 218
Issue: 7
Pages: 2247-2264
Publication
First Author: Gao Y
Year: 2012
Journal: Dev Cell
Title: Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes.
Volume: 22
Issue: 3
Pages: 573-84
Publication
First Author: Shiba Y
Year: 2011
Journal: Biochem Biophys Res Commun
Title: GEFH1 binds ASAP1 and regulates podosome formation.
Volume: 406
Issue: 4
Pages: 574-9
Publication
First Author: Tonami K
Year: 2011
Journal: J Cell Sci
Title: Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1.
Volume: 124
Issue: Pt 8
Pages: 1214-23
Publication
First Author: Chiang HS
Year: 2014
Journal: Nat Immunol
Title: GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses.
Volume: 15
Issue: 1
Pages: 63-71
Publication
First Author: Kashyap AS
Year: 2019
Journal: Cell Rep
Title: GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses.
Volume: 28
Issue: 13
Pages: 3367-3380.e8
Publication
First Author: Cullis J
Year: 2014
Journal: Cancer Cell
Title: The RhoGEF GEF-H1 is required for oncogenic RAS signaling via KSR-1.
Volume: 25
Issue: 2
Pages: 181-95
Publication
First Author: Zhao Y
Year: 2019
Journal: Nat Commun
Title: Microbial recognition by GEF-H1 controls IKKε mediated activation of IRF5.
Volume: 10
Issue: 1
Pages: 1349
Publication
First Author: Danilenko DM
Year: 1995
Journal: Am J Pathol
Title: Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia.
Volume: 147
Issue: 1
Pages: 145-54
Publication
First Author: Ryan XP
Year: 2005
Journal: Neuron
Title: The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology.
Volume: 47
Issue: 1
Pages: 85-100
Publication
First Author: Noren Hooten N
Year: 2011
Journal: J Biol Chem
Title: Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1).
Volume: 286
Issue: 52
Pages: 44679-90
Publication
First Author: Tsuji T
Year: 2010
Journal: Mol Biol Cell
Title: Involvement of p114-RhoGEF and Lfc in Wnt-3a- and dishevelled-induced RhoA activation and neurite retraction in N1E-115 mouse neuroblastoma cells.
Volume: 21
Issue: 20
Pages: 3590-600
Publication
First Author: Yoshizawa M
Year: 2003
Journal: Gene Expr Patterns
Title: Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.
Volume: 3
Issue: 3
Pages: 375-81
Publication
First Author: Munton RP
Year: 2007
Journal: Mol Cell Proteomics
Title: Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.
Volume: 6
Issue: 2
Pages: 283-93
Publication
First Author: Okazaki N
Year: 2002
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 9
Issue: 5
Pages: 179-88
Publication      
First Author: Centre for Modeling Human Disease
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50