Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
AT-rich interactive domain-containing protein 4B (ARID4B) acts as a transcriptional repressor. It may function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes []. It may play an integral part in the AR (androgen receptor) and RB (retinoblastoma) regulatory pathways involved in the regulation of Sertoli cell function and male fertility []. It is linked to tumor growth and metastasis []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu RC |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways. |
Volume: |
110 |
Issue: |
12 |
Pages: |
4616-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu RC |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Identification of the PTEN-ARID4B-PI3K pathway reveals the dependency on ARID4B by PTEN-deficient prostate cancer. |
Volume: |
10 |
Issue: |
1 |
Pages: |
4332 |
|
•
•
•
•
•
|
Publication |
First Author: |
Young IC |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling. |
Volume: |
37 |
Issue: |
8 |
Pages: |
110036 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu MY |
Year: |
2008 |
Journal: |
J Natl Cancer Inst |
Title: |
Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes. |
Volume: |
100 |
Issue: |
17 |
Pages: |
1247-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu RC |
Year: |
2015 |
Journal: |
Mol Endocrinol |
Title: |
Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis. |
Volume: |
29 |
Issue: |
9 |
Pages: |
1334-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu RC |
Year: |
2017 |
Journal: |
Stem Cells |
Title: |
Temporal-Spatial Establishment of Initial Niche for the Primary Spermatogonial Stem Cell Formation Is Determined by an ARID4B Regulatory Network. |
Volume: |
35 |
Issue: |
6 |
Pages: |
1554-1565 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winter SF |
Year: |
2012 |
Journal: |
PLoS Genet |
Title: |
Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis. |
Volume: |
8 |
Issue: |
5 |
Pages: |
e1002735 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6890490 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-03-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6890495 |
Age: |
embryonic day 13.5 |
Image: |
3D Arid4b HC+/+ |
|
Specimen Label: |
3D Arid4b HC+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6890490 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2022-03-17 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684622 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:6890495 |
Age: |
embryonic day 13.5 |
Image: |
3D Arid4b HC-/- |
Note: |
Abundant expression in fetal livers. |
Specimen Label: |
3D Arid4b HC-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1314
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
238
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
538
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
398
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
128
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
540
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
473
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
270
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Fleischer TC |
Year: |
2003 |
Journal: |
Mol Cell Biol |
Title: |
Identification and characterization of three new components of the mSin3A corepressor complex. |
Volume: |
23 |
Issue: |
10 |
Pages: |
3456-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goldberger N |
Year: |
2013 |
Journal: |
Cancer Res |
Title: |
Inherited variation in miR-290 expression suppresses breast cancer progression by targeting the metastasis susceptibility gene Arid4b. |
Volume: |
73 |
Issue: |
8 |
Pages: |
2671-81 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6369701 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797227 |
|
Stage: |
TS27 |
Assay Id: |
MGI:6369809 |
Age: |
postnatal day 0.5 |
|
|
Specimen Label: |
1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6369701 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6369809 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6369701 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6369809 |
Age: |
postnatal day 42 |
|
|
Specimen Label: |
3 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6369701 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-11-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6369809 |
Age: |
postnatal day 42 |
|
|
Specimen Label: |
4 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1868128 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6692363 |
Age: |
postnatal adult |
Image: |
BCM_2399351 |
Note: |
vas deferens |
Specimen Label: |
BCM_2399351 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6369703 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2019-11-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2910623 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:6369807 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
1D Control E15.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6369703 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2019-11-06 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2910623 |
|
Stage: |
TS23 |
Assay Id: |
MGI:6369807 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
1D Arid4bSCKO E15.5 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6369703 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2019-11-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2910628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6369807 |
Age: |
postnatal day 42 |
|
|
Specimen Label: |
1D Control P42 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6369703 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2019-11-06 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2910628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6369807 |
Age: |
postnatal day 42 |
|
|
Specimen Label: |
1D Arid4bSCKO P42 |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692363 |
Age: |
postnatal adult |
Image: |
BCM_2399351 |
|
Specimen Label: |
BCM_2399351 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng Y |
Year: |
2013 |
Journal: |
Mol Biotechnol |
Title: |
Generation and characterization of yeast two-hybrid cDNA libraries derived from two distinct mouse pluripotent cell types. |
Volume: |
54 |
Issue: |
2 |
Pages: |
228-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu MY |
Year: |
2006 |
Journal: |
Genes Dev |
Title: |
Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain. |
Volume: |
20 |
Issue: |
20 |
Pages: |
2859-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilsker D |
Year: |
2005 |
Journal: |
Genomics |
Title: |
Nomenclature of the ARID family of DNA-binding proteins. |
Volume: |
86 |
Issue: |
2 |
Pages: |
242-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Williams K |
Year: |
2011 |
Journal: |
Nature |
Title: |
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. |
Volume: |
473 |
Issue: |
7347 |
Pages: |
343-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mann KM |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. |
Volume: |
109 |
Issue: |
16 |
Pages: |
5934-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
1998 |
Journal: |
Mol Cell |
Title: |
SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. |
Volume: |
1 |
Issue: |
7 |
Pages: |
1021-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martin N |
Year: |
2001 |
Journal: |
Genomics |
Title: |
Genetic and physical delineation of the region overlapping the progressive motor neuropathy (pmn) locus on mouse chromosome 13. |
Volume: |
75 |
Issue: |
1-3 |
Pages: |
9-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Streubel G |
Year: |
2017 |
Journal: |
EMBO J |
Title: |
Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal. |
Volume: |
36 |
Issue: |
15 |
Pages: |
2216-2232 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muñoz IM |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex. |
Volume: |
287 |
Issue: |
39 |
Pages: |
32346-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith KT |
Year: |
2012 |
Journal: |
Mol Cell Proteomics |
Title: |
Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex. |
Volume: |
11 |
Issue: |
12 |
Pages: |
1815-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bulfone A |
Year: |
2005 |
Journal: |
J Neurosci |
Title: |
Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. |
Volume: |
25 |
Issue: |
33 |
Pages: |
7586-600 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
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