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Search results 1 to 100 out of 103 for Arpc3

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Type Details Score
Gene
10094 | ARPC3
Type: gene
Organism: human
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Gene
737048 | ARPC3
Type: gene
Organism: chimpanzee
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Gene
506596 | ARPC3
Type: gene
Organism: cattle
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Gene
100856747 | ARPC3
Type: gene
Organism: dog, domestic
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Gene
416837 | ARPC3
Type: gene
Organism: chicken
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Gene
415204 | arpc3
Type: gene
Organism: zebrafish
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Gene
709199 | ARPC3
Type: gene
Organism: macaque, rhesus
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Gene
100038232 | arpc3
Type: gene
Organism: frog, western clawed
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Gene
288669 | Arpc3
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1928375 | Arpc3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR007204 | ARPC3
Type: Family
Description: Arp2/3 binds to pre-existing actin filaments and nucleates new daughter filaments, and thus becomes incorporated into the dynamic actin network at the leading edge of motile cells and other actin-based protrusive structures []. In order to nucleate filaments, Arp2/3 must bind to a member of the N-WASp/SCAR family protein []. Arp2 and Arp3 are thought to be brought together after activation, forming an actin-like nucleus for actin monomers to bind and create a new actin filament. In the absence of an activating protein, Arp2/3 shows very little nucleation activity. Recent research has focused on the binding and hydrolysis of ATP by Arp2 and Arp3 [], and crystal structures of the Arp2/3 complex have been solved [].The human complex consists of Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. This family represents the ARPC3/p21-ARC subunit.
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Publication
21930776 | J:177728
First Author: Lippi G
Year: 2011
Journal: J Cell Biol
Title: Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology.
Volume: 194
Issue: 6
Pages: 889-904
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Publication
16880528 | J:111402
First Author: Yae K
Year: 2006
Journal: Mol Cell Biol
Title: Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth.
Volume: 26
Issue: 16
Pages: 6185-96
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Protein
Q9JM76
Organism: Mus musculus/domesticus
Length: 178  
Fragment?: false
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Protein
D3Z2F8
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: false
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Protein
H7BWZ3
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: false
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Protein
A0A0G2JFK7
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
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Protein
D3Z2F7
Organism: Mus musculus/domesticus
Length: 161  
Fragment?: false
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Publication
9889097 | -
First Author: Machesky LM
Year: 1998
Journal: Curr Biol
Title: Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex.
Volume: 8
Issue: 25
Pages: 1347-56
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Publication
15505213 | -
First Author: Nolen BJ
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP.
Volume: 101
Issue: 44
Pages: 15627-32
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Publication
9600938 | -
First Author: Mullins RD
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments.
Volume: 95
Issue: 11
Pages: 6181-6
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Publication
11752435 | -
First Author: Dayel MJ
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Arp2/3 complex requires hydrolyzable ATP for nucleation of new actin filaments.
Volume: 98
Issue: 26
Pages: 14871-6
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Publication
32726629 | J:300862
First Author: Kim IH
Year: 2020
Journal: Cell Rep
Title: Dysregulation of the Synaptic Cytoskeleton in the PFC Drives Neural Circuit Pathology, Leading to Social Dysfunction.
Volume: 32
Issue: 4
Pages: 107965
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Publication
22492726 | J:185040
First Author: Suraneni P
Year: 2012
Journal: J Cell Biol
Title: The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration.
Volume: 197
Issue: 2
Pages: 239-51
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Publication
31843915 | J:285830
     
First Author: Spencer WJ
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Photoreceptor disc membranes are formed through an Arp2/3-dependent lamellipodium-like mechanism.
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Publication
23554489 | J:196577
First Author: Kim IH
Year: 2013
Journal: J Neurosci
Title: Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities.
Volume: 33
Issue: 14
Pages: 6081-92
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Publication
24043783 | J:201137
First Author: Zhou K
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Actin-related protein2/3 complex regulates tight junctions and terminal differentiation to promote epidermal barrier formation.
Volume: 110
Issue: 40
Pages: E3820-9
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Protein Coding Gene
MGP_CAROLIEiJ_G0027706 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029952 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029744 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1928375 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030480 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029153 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029820 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029851 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028867 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024286 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028704 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
25938885 | J:222963
First Author: Kim IH
Year: 2015
Journal: Nat Neurosci
Title: Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine.
Volume: 18
Issue: 6
Pages: 883-91
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GXD Expression
GXD Expression
     
Probe: MGI:3758755
Assay Type: RT-PCR
Annotation Date: 2007-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1791723
Stage: TS23
Assay Id: MGI:3758773
Age: embryonic day 15.5
Specimen Label: E15.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3758755
Assay Type: RT-PCR
Annotation Date: 2007-10-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3290627
Stage: TS27
Assay Id: MGI:3758773
Age: postnatal day 2
Specimen Label: 2DPN
Detected: true
Specimen Num: 2
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Publication
- | J:66350
   
First Author: Sugiura S
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mRNA for Arp2/3 complex subunit p21-Arc, complete cds
Pages: AB038243
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Publication
23727094 | J:199839
First Author: Ydenberg CA
Year: 2013
Journal: Curr Biol
Title: GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism.
Volume: 23
Issue: 12
Pages: 1037-45
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Publication
34269176 | J:317350
   
First Author: O'Neil SD
Year: 2021
Journal: Elife
Title: Action potential-coupled Rho GTPase signaling drives presynaptic plasticity.
Volume: 10
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Publication
27629719 | J:235496
First Author: Spence EF
Year: 2016
Journal: J Neurosci
Title: The Arp2/3 Complex Is Essential for Distinct Stages of Spine Synapse Maturation, Including Synapse Unsilencing.
Volume: 36
Issue: 37
Pages: 9696-709
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Publication
22689987 | J:185589
First Author: Maritzen T
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Gadkin negatively regulates cell spreading and motility via sequestration of the actin-nucleating ARP2/3 complex.
Volume: 109
Issue: 26
Pages: 10382-7
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Publication
26997484 | J:234410
First Author: Zhang Y
Year: 2016
Journal: Cell
Title: Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating.
Volume: 165
Issue: 2
Pages: 434-448
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Publication
18289379 | J:164711
 
First Author: Ma T
Year: 2008
Journal: J Mol Signal
Title: Dramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acid.
Volume: 3
Pages: 4
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Publication
14645530 | J:104039
First Author: Horie K
Year: 2003
Journal: Mol Cell Biol
Title: Characterization of Sleeping Beauty transposition and its application to genetic screening in mice.
Volume: 23
Issue: 24
Pages: 9189-207
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Publication
26166300 | J:239800
First Author: Zuchero JB
Year: 2015
Journal: Dev Cell
Title: CNS myelin wrapping is driven by actin disassembly.
Volume: 34
Issue: 2
Pages: 152-67
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Publication
25926623 | J:223805
First Author: Moehle MS
Year: 2015
Journal: Hum Mol Genet
Title: The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.
Volume: 24
Issue: 15
Pages: 4250-67
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Publication
12473693 | J:80756
First Author: DeMali KA
Year: 2002
Journal: J Cell Biol
Title: Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion.
Volume: 159
Issue: 5
Pages: 881-91
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Publication
15294161 | J:91946
First Author: Mejillano MR
Year: 2004
Journal: Cell
Title: Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end.
Volume: 118
Issue: 3
Pages: 363-73
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Publication
35296311 | J:327181
First Author: Lewis MA
Year: 2022
Journal: BMC Biol
Title: Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme.
Volume: 20
Issue: 1
Pages: 67
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Publication
31146259 | J:285722
First Author: Liu Y
Year: 2019
Journal: Reproduction
Title: The sperm-associated antigen 6 interactome and its role in spermatogenesis.
Volume: 158
Issue: 2
Pages: 181-197
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Publication
17374359 | J:123755
First Author: Osmundsen H
Year: 2007
Journal: Arch Oral Biol
Title: Changes in gene-expression during development of the murine molar tooth germ.
Volume: 52
Issue: 9
Pages: 803-13
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
33353942 | J:302833
First Author: Fäßler F
Year: 2020
Journal: Nat Commun
Title: Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction.
Volume: 11
Issue: 1
Pages: 6437
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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