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Search results 1 to 88 out of 88 for Arpc4

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Hits by Category

Type Details Score
Gene
10093 | ARPC4
Type: gene
Organism: human
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Gene
539459 | ARPC4
Type: gene
Organism: cattle
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Gene
100614809 | ARPC4
Type: gene
Organism: chimpanzee
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Gene
416051 | ARPC4
Type: gene
Organism: chicken
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Gene
114456 | arpc4
Type: gene
Organism: zebrafish
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Gene
448127 | arpc4
Type: gene
Organism: frog, western clawed
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Gene
106560075 | ARPC4
Type: gene
Organism: dog, domestic
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Gene
106996837 | ARPC4
Type: gene
Organism: macaque, rhesus
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Gene
297518 | Arpc4
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1915339 | Arpc4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR008384 | ARPC4
Type: Family
Description: Arp2/3 binds to pre-existing actin filaments and nucleates new daughter filaments, and thus becomes incorporated into the dynamic actin network at the leading edge of motile cells and other actin-based protrusive structures []. In order to nucleate filaments, Arp2/3 must bind to a member of the N-WASp/SCAR family protein []. Arp2 and Arp3 are thought to be brought together after activation, forming an actin-like nucleus for actin monomers to bind and create a new actin filament. In the absence of an activating protein, Arp2/3 shows very little nucleation activity. Recent research has focused on the binding and hydrolysis of ATP by Arp2 and Arp3 [], and crystal structures of the Arp2/3 complex have been solved [].The human complex consists of Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. This family represents the ARPC4/p20-ARC subunit.
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Protein
P59999
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
Q3TX55
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: false
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Protein
Q8BVW6
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
E9PWA7
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: false
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Protein
Q7TPD9
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
Q9D3C4
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Publication
9889097 | -
First Author: Machesky LM
Year: 1998
Journal: Curr Biol
Title: Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex.
Volume: 8
Issue: 25
Pages: 1347-56
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Publication
15505213 | -
First Author: Nolen BJ
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP.
Volume: 101
Issue: 44
Pages: 15627-32
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Publication
9600938 | -
First Author: Mullins RD
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments.
Volume: 95
Issue: 11
Pages: 6181-6
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Publication
11752435 | -
First Author: Dayel MJ
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Arp2/3 complex requires hydrolyzable ATP for nucleation of new actin filaments.
Volume: 98
Issue: 26
Pages: 14871-6
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Publication
29113991 | J:253986
First Author: van der Kammen R
Year: 2017
Journal: Development
Title: Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2.
Volume: 144
Issue: 24
Pages: 4588-4603
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Publication
33388318 | J:314686
First Author: Zhao Y
Year: 2021
Journal: Gastroenterology
Title: mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote KrasG12D-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Volume: 160
Issue: 5
Pages: 1755-1770.e17
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Protein Coding Gene
MGP_CAROLIEiJ_G0028723 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0031120 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0031089 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0031020 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0031100 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030608 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1915339 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031559 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030786 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030893 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0031019 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031586 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030291 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022474 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029751 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
31416964 | J:278083
First Author: Krndija D
Year: 2019
Journal: Science
Title: Active cell migration is critical for steady-state epithelial turnover in the gut.
Volume: 365
Issue: 6454
Pages: 705-710
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GXD Expression
GXD Expression
 
Probe: MGI:1036648
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823253
Age: embryonic day 14.5
Image: euxassay_002361_09
Specimen Label: euxassay_002361_09
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1036648
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823253
Age: embryonic day 14.5
Image: euxassay_002361_10
Specimen Label: euxassay_002361_10
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1036648
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823253
Age: embryonic day 14.5
Image: euxassay_002361_16
Specimen Label: euxassay_002361_16
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1036648
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823253
Age: embryonic day 14.5
Image: euxassay_002361_17
Specimen Label: euxassay_002361_17
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1036648
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1666823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823253
Age: embryonic day 14.5
Image: euxassay_002361_18
Specimen Label: euxassay_002361_18
Detected: true
Specimen Num: 5
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Publication
- | J:72495
   
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, actin related protein 2/3 complex, subunit 4 (20 kD), clone MGC: 18865 IMAGE: 4223594, mRNA, complete cds
Pages: BC015280
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Publication
34910930 | J:320370
First Author: Rivera CA
Year: 2022
Journal: Immunity
Title: Epithelial colonization by gut dendritic cells promotes their functional diversification.
Volume: 55
Issue: 1
Pages: 129-144.e8
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Publication
33903241 | J:309471
 
First Author: Figueiredo AM
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Endothelial cell invasion is controlled by dactylopodia.
Volume: 118
Issue: 18
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Publication
12473693 | J:80756
First Author: DeMali KA
Year: 2002
Journal: J Cell Biol
Title: Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion.
Volume: 159
Issue: 5
Pages: 881-91
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Publication
- | J:165965
     
First Author: Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource
Year: 2010
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from Europhenome
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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