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Search results 1 to 98 out of 98 for Arv1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
64801 | ARV1
Type: gene
Organism: human
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Gene
488975 | ARV1
Type: gene
Organism: dog, domestic
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Gene
515046 | ARV1
Type: gene
Organism: cattle
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Gene
421546 | ARV1
Type: gene
Organism: chicken
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Gene
568203 | arv1
Type: gene
Organism: zebrafish
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Gene
713975 | ARV1
Type: gene
Organism: macaque, rhesus
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Gene
549206 | arv1
Type: gene
Organism: frog, western clawed
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Gene
292097 | Arv1
Type: gene
Organism: rat
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Gene
457815 | ARV1
Type: gene
Organism: chimpanzee
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Protein Domain
IPR007290 | Arv1
Type: Family
Description: Arv1 is a transmembrane protein, with potential zinc-binding motifs, that mediates sterol homeostasis. Its action is important in lipid homeostasis, which prevents free sterol toxicity []. Arv1 contains a homology domain (AHD), which consists of an N-terminal cysteine-rich subdomain with a putative zinc-binding motif, followed by a C-terminal subdomain of 33 amino acids. The C-terminal subdomain of the AHD is critical for the protein's function []. In yeast, Arv1p is important for the delivery of an early glycosylphosphatidylinositol GPI intermediate, GlcN-acylPI, to the first mannosyltransferase of GPI synthesis in the ER lumen []. It is important for the traffic of sterol in yeast and in humans. In eukaryotic cells, it may fuction in the sphingolipid metabolic pathway as a transporter of ceramides between the ER and Golgi []. Arabidopsis thaliana has been shown to encode 2 ARV proteins (ARV1 and ARV2) both of which contain the AHD domain. This family also includes ARV2 from A. thaliana [].
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Protein Coding Gene
MGI:1916115 | Arv1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27270415 | J:237145
First Author: Palmer EE
Year: 2016
Journal: Hum Mol Genet
Title: Neuronal deficiency of ARV1 causes an autosomal recessive epileptic encephalopathy.
Volume: 25
Issue: 14
Pages: 3042-3054
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Protein
Q9D0U9
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Publication
20663892 | J:166805
First Author: Tong F
Year: 2010
Journal: J Biol Chem
Title: Decreased expression of ARV1 results in cholesterol retention in the endoplasmic reticulum and abnormal bile acid metabolism.
Volume: 285
Issue: 44
Pages: 33632-41
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Publication
11063737 | -
First Author: Tinkelenberg AH
Year: 2000
Journal: J Biol Chem
Title: Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1.
Volume: 275
Issue: 52
Pages: 40667-70
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Publication
12145310 | -
First Author: Swain E
Year: 2002
Journal: J Biol Chem
Title: Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1.
Volume: 277
Issue: 39
Pages: 36152-60
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Publication
18287539 | -
First Author: Kajiwara K
Year: 2008
Journal: Mol Biol Cell
Title: Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.
Volume: 19
Issue: 5
Pages: 2069-82
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Publication
26479315 | J:241193
 
First Author: Lagor WR
Year: 2015
Journal: Nutr Diabetes
Title: Deletion of murine Arv1 results in a lean phenotype with increased energy expenditure.
Volume: 5
Pages: e181
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Protein
A0A1D5RLE6
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
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Protein
A0A1D5RLR4
Organism: Mus musculus/domesticus
Length: 112  
Fragment?: false
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Protein
Q0VBH5
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Publication
16725371 | -
First Author: Forés O
Year: 2006
Journal: Biochim Biophys Acta
Title: Arabidopsis thaliana expresses two functional isoforms of Arvp, a protein involved in the regulation of cellular lipid homeostasis.
Volume: 1761
Issue: 7
Pages: 725-35
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Publication
29491146 | J:263695
First Author: Gallo-Ebert C
Year: 2018
Journal: J Biol Chem
Title: Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease.
Volume: 293
Issue: 16
Pages: 5956-5974
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Protein Coding Gene
MGP_CAROLIEiJ_G0031710 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_AJ_G0034256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034249 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1916115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033287 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034089 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034178 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033404 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_SPRETEiJ_G0032828 | -
Type: protein_coding_gene
Organism: Mus spretus
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Protein Coding Gene
MGP_129S1SvImJ_G0034276 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034183 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033960 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034769 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033933 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034033 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034080 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032989 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023308 | -
Type: protein_coding_gene
Organism: Mus pahari
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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UniProt Feature
UniProt Feature
Begin: 1
Description: Protein ARV1
Type: chain
End: 266
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Allele
Arv1<tm1.2Geno> | MGI:6356538
Name: ARV1 homolog, fatty acid homeostasis modulator; targeted mutation 1.2, Genoway
Allele Type: Targeted
Attribute String: Null/knockout
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Gene
108716674 | arv1.L
Type: gene
Organism: frog, African clawed
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Gene
108717824 | arv1.S
Type: gene
Organism: frog, African clawed
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Genotype
Genotype
Symbol: Arv1/Arv1
Background: involves: C57BL/6 * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arv1/Arv1<+>
Background: involves: C57BL/6 * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Allele
Arv1<tm1.1Geno> | MGI:6356536
Name: ARV1 homolog, fatty acid homeostasis modulator; targeted mutation 1.1, Genoway
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Arv1<em1(IMPC)J> | MGI:5810348
Name: ARV1 homolog, fatty acid homeostasis modulator; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Arv1<+> | MGI:3505554
   
Name: ARV1 homolog, fatty acid homeostasis modulator; wild type
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Allele
Arv1<tm1.1Radr> | MGI:6149716
Name: ARV1 homolog, fatty acid homeostasis modulator; targeted mutation 1.1, Daniel J Rader
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Arv1<tm1a(EUCOMM)Wtsi> | MGI:5286407
Name: ARV1 homolog, fatty acid homeostasis modulator; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Arv1<Gt(OST91097)Lex> | MGI:4180071
 
Name: ARV1 homolog, fatty acid homeostasis modulator; gene trap OST91097, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Arv1<tm1e(EUCOMM)Wtsi> | MGI:5296216
Name: ARV1 homolog, fatty acid homeostasis modulator; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Arv1<Gt(OST274450)Lex> | MGI:4259468
 
Name: ARV1 homolog, fatty acid homeostasis modulator; gene trap OST274450, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Arv1<Gt(E118B12)Wrst> | MGI:3896080
 
Name: ARV1 homolog, fatty acid homeostasis modulator; gene trap E118B12, German Gene Trap Consortium
Allele Type: Gene trapped
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Strain
MGI:5810639 | C57BL/6NJ-Arv1<em1(IMPC)J>/Mmjax
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Arv1<Gt(OST437687)Lex> | MGI:4317060
 
Name: ARV1 homolog, fatty acid homeostasis modulator; gene trap OST437687, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Arv1<Gt(OST155145)Lex> | MGI:4207934
 
Name: ARV1 homolog, fatty acid homeostasis modulator; gene trap OST155145, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Arv1<Gt(EUCE0045h07)Hmgu> | MGI:4385390
 
Name: ARV1 homolog, fatty acid homeostasis modulator; gene trap EUCE0045h07, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Arv1<tm1.2Radr> | MGI:6149717
Name: ARV1 homolog, fatty acid homeostasis modulator; targeted mutation 1.2, Daniel J Rader
Allele Type: Targeted
Attribute String: Not Specified
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Allele
Arv1<Gt(OST86641)Lex> | MGI:4178681
 
Name: ARV1 homolog, fatty acid homeostasis modulator; gene trap OST86641, Lexicon Genetics
Allele Type: Gene trapped
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Genotype
Genotype
Symbol: Arv1/Arv1
Background: C57BL/6NJ-Arv1/Mmjax
Zygosity: hm
Has Mutant Allele: true
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Allele
Arv1<Gt(IST14455A12)Tigm> | MGI:5234703
 
Name: ARV1 homolog, fatty acid homeostasis modulator; gene trap IST14455A12, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
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Genotype
Genotype
Symbol: Arv1/Arv1
Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0080417 | developmental and epileptic encephalopathy 38
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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