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Search results 1 to 100 out of 493 for Atf2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: Activating transcription factor or cAMP-dependent transcription factor ATF-2, also known as CRE-BP1, regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. ATF-2 needs to be phosphorylated by Jun N-terminal kinase (JNK), p38 (MAPK14), or extracellular-signal-regulated kinase 1 (ERK1) in order to be transcriptionally active. Activated ATF-2 then form dimers with proteins, such as members of the AP-1 family, and regulates gene transcription []. It has been implicated in several pathological conditions, including neurological diseases and cancer [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
Publication
First Author: Claps G
Year: 2016
Journal: Cell Rep
Title: A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis.
Volume: 15
Issue: 9
Pages: 1884-92
Publication
First Author: Lau E
Year: 2012
Journal: J Cell Sci
Title: ATF2 - at the crossroad of nuclear and cytosolic functions.
Volume: 125
Issue: Pt 12
Pages: 2815-24
Publication
First Author: Meijer BJ
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair.
Volume: 10
Issue: 1
Pages: 23-42
Publication
First Author: Shah M
Year: 2010
Journal: PLoS Genet
Title: A role for ATF2 in regulating MITF and melanoma development.
Volume: 6
Issue: 12
Pages: e1001258
Publication
First Author: Kim S
Year: 2006
Journal: Blood
Title: Arrested natural killer cell development associated with transgene insertion into the Atf2 locus.
Volume: 107
Issue: 3
Pages: 1024-30
Publication
First Author: Kumar V
Year: 2018
Journal: BMC Neurosci
Title: PKCε phosphorylation regulates the mitochondrial translocation of ATF2 in ischemia-induced neurodegeneration.
Volume: 19
Issue: 1
Pages: 76
Publication
First Author: Fischer K
Year: 2020
Journal: Nat Commun
Title: The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Volume: 11
Issue: 1
Pages: 2306
Publication
First Author: Bhoumik A
Year: 2005
Journal: Mol Cell
Title: ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.
Volume: 18
Issue: 5
Pages: 577-87
Publication
First Author: Bruhat A
Year: 2007
Journal: Nucleic Acids Res
Title: ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation.
Volume: 35
Issue: 4
Pages: 1312-21
Publication
First Author: Breitwieser W
Year: 2007
Journal: Genes Dev
Title: Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells.
Volume: 21
Issue: 16
Pages: 2069-82
Publication
First Author: Wang LS
Year: 2013
Journal: Genet Mol Res
Title: Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations.
Volume: 12
Issue: 4
Pages: 5992-6005
Publication
First Author: Ackermann J
Year: 2011
Journal: PLoS One
Title: Loss of ATF2 function leads to cranial motoneuron degeneration during embryonic mouse development.
Volume: 6
Issue: 4
Pages: e19090
GXD Expression    
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189820
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Atf2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189820
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Atf2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189820
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Atf2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189820
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Atf2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189820
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Atf2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189820
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Atf2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189820
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Atf2
Detected: true
Specimen Num: 7
Publication
First Author: Firestein R
Year: 1998
Journal: J Biol Chem
Title: Association of activating transcription factor 2 (ATF2) with the ubiquitin-conjugating enzyme hUBC9. Implication of the ubiquitin/proteasome pathway in regulation of ATF2 in T cells.
Volume: 273
Issue: 10
Pages: 5892-902
Protein
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 240  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
Publication
First Author: Chen SY
Year: 2008
Journal: J Cutan Pathol
Title: Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous angiosarcoma and pyogenic granuloma.
Volume: 35
Issue: 8
Pages: 722-30
Publication
First Author: Pearson AG
Year: 2005
Journal: Neuroscience
Title: Activating transcription factor 2 expression in the adult human brain: association with both neurodegeneration and neurogenesis.
Volume: 133
Issue: 2
Pages: 437-51
Publication
First Author: Bhoumik A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Suppressor role of activating transcription factor 2 (ATF2) in skin cancer.
Volume: 105
Issue: 5
Pages: 1674-9
Publication
First Author: Lee MR
Year: 1992
Journal: J Immunol
Title: Isolation and characterization of nuclear proteins that bind to T cell receptor V beta decamer motif.
Volume: 148
Issue: 6
Pages: 1906-12
Publication
First Author: Gozdecka M
Year: 2014
Journal: Cell Rep
Title: JNK suppresses tumor formation via a gene-expression program mediated by ATF2.
Volume: 9
Issue: 4
Pages: 1361-74
Publication
First Author: Liu Y
Year: 2009
Journal: Cancer Res
Title: Activating transcription factor 2 and c-Jun-mediated induction of FoxP3 for experimental therapy of mammary tumor in the mouse.
Volume: 69
Issue: 14
Pages: 5954-60
Publication
First Author: Su L
Year: 2012
Journal: Cancer Cell
Title: Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics.
Volume: 21
Issue: 3
Pages: 333-47
Publication
First Author: Kawai S
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Negative regulation of Odd-skipped related 2 by TGF-beta achieves the induction of cellular migration and the arrest of cell cycle.
Volume: 421
Issue: 4
Pages: 696-700
Publication
First Author: Lin WC
Year: 2002
Journal: DNA Cell Biol
Title: Transcriptional activation of C/EBPbeta gene by c-Jun and ATF2.
Volume: 21
Issue: 8
Pages: 551-60
Publication
First Author: Satake H
Year: 2009
Journal: Dev Growth Differ
Title: Spatio-temporal expression of activating transcription factor 5 in the skeletal development of mouse limb.
Volume: 51
Issue: 7
Pages: 669-76
Publication
First Author: Blank U
Year: 2009
Journal: Development
Title: BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanism.
Volume: 136
Issue: 21
Pages: 3557-66
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Georgopoulos K
Year: 1992
Journal: Mol Cell Biol
Title: Functionally distinct isoforms of the CRE-BP DNA-binding protein mediate activity of a T-cell-specific enhancer.
Volume: 12
Issue: 2
Pages: 747-57
Publication
First Author: Reimold AM
Year: 1996
Journal: Nature
Title: Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice.
Volume: 379
Issue: 6562
Pages: 262-5
Publication
First Author: Kim S
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: In vivo natural killer cell activities revealed by natural killer cell-deficient mice.
Volume: 97
Issue: 6
Pages: 2731-6
Publication  
First Author: de Vries MR
Year: 2013
Journal: J Mol Cell Cardiol
Title: C57BL/6 NK cell gene complex is crucially involved in vascular remodeling.
Volume: 64
Pages: 51-8
Publication
First Author: French AR
Year: 2007
Journal: J Allergy Clin Immunol
Title: Chronic lymphocytosis of functionally immature natural killer cells.
Volume: 120
Issue: 4
Pages: 924-31
Publication
First Author: Maekawa T
Year: 2007
Journal: Mol Cell Biol
Title: Reduced levels of ATF-2 predispose mice to mammary tumors.
Volume: 27
Issue: 5
Pages: 1730-44
Publication
First Author: Reimold AM
Year: 2001
Journal: Int Immunol
Title: Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice.
Volume: 13
Issue: 2
Pages: 241-8
GXD Expression      
Probe: MGI:1303109
Assay Type: Northern blot
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1329106
Age: embryonic day 12.5
Specimen Label: 12
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:1303109
Assay Type: Northern blot
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:1329106
Age: embryonic day 14.5
Specimen Label: 13
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:3784249
Assay Type: RT-PCR
Annotation Date: 2008-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654814
Stage: TS14
Assay Id: MGI:3784412
Age: embryonic day 9.0
Image: 4
Specimen Label: 16-20s
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3784249
Assay Type: RT-PCR
Annotation Date: 2008-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654815
Stage: TS15
Assay Id: MGI:3784412
Age: embryonic day 9.5
Image: 4
Specimen Label: 26-30s
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816421
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816421
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816421
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816421
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816421
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816421
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816421
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816421
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:4458357
Assay Type: RT-PCR
Annotation Date: 2010-07-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:4458364
Age: postnatal
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4458357
Assay Type: RT-PCR
Annotation Date: 2010-07-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:4458364
Age: postnatal
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4458367
Assay Type: Northern blot
Annotation Date: 2010-07-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4458368
Age: postnatal
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1