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Search results 1 to 100 out of 499 for Atf2

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
1386 | ATF2
Type: gene
Organism: human
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Gene
100485532 | atf2
Type: gene
Organism: frog, western clawed
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Gene
81647 | Atf2
Type: gene
Organism: rat
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Gene
478806 | ATF2
Type: gene
Organism: dog, domestic
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Gene
509827 | ATF2
Type: gene
Organism: cattle
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Gene
101059354 | ATF2
Type: gene
Organism: chimpanzee
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Gene
395727 | ATF2
Type: gene
Organism: chicken
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Gene
100006516 | atf2
Type: gene
Organism: zebrafish
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Gene
699072 | ATF2
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR029836 | ATF2
Type: Family
Description: Activating transcription factor or cAMP-dependent transcription factor ATF-2, also known as CRE-BP1, regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. ATF-2 needs to be phosphorylated by Jun N-terminal kinase (JNK), p38 (MAPK14), or extracellular-signal-regulated kinase 1 (ERK1) in order to be transcriptionally active. Activated ATF-2 then form dimers with proteins, such as members of the AP-1 family, and regulates gene transcription []. It has been implicated in several pathological conditions, including neurological diseases and cancer [, ].
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Protein Coding Gene
MGI:109349 | Atf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q640L6
Organism: Mus musculus/domesticus
Length: 389  
Fragment?: false
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Protein
Q68FE3
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: false
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Protein
Q8CGB4
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
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Publication
27210757 | J:235959
First Author: Claps G
Year: 2016
Journal: Cell Rep
Title: A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis.
Volume: 15
Issue: 9
Pages: 1884-92
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Publication
22685333 | -
First Author: Lau E
Year: 2012
Journal: J Cell Sci
Title: ATF2 - at the crossroad of nuclear and cytosolic functions.
Volume: 125
Issue: Pt 12
Pages: 2815-24
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Publication
31958521 | J:298783
First Author: Meijer BJ
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair.
Volume: 10
Issue: 1
Pages: 23-42
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Publication
21203491 | J:167512
First Author: Shah M
Year: 2010
Journal: PLoS Genet
Title: A role for ATF2 in regulating MITF and melanoma development.
Volume: 6
Issue: 12
Pages: e1001258
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Publication
16223777 | J:127589
First Author: Kim S
Year: 2006
Journal: Blood
Title: Arrested natural killer cell development associated with transgene insertion into the Atf2 locus.
Volume: 107
Issue: 3
Pages: 1024-30
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Publication
30497386 | J:318555
First Author: Kumar V
Year: 2018
Journal: BMC Neurosci
Title: PKCε phosphorylation regulates the mitochondrial translocation of ATF2 in ischemia-induced neurodegeneration.
Volume: 19
Issue: 1
Pages: 76
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Publication
15916964 | J:240286
First Author: Bhoumik A
Year: 2005
Journal: Mol Cell
Title: ATM-dependent phosphorylation of ATF2 is required for the DNA damage response.
Volume: 18
Issue: 5
Pages: 577-87
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Publication
32385399 | J:292035
First Author: Fischer K
Year: 2020
Journal: Nat Commun
Title: The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation.
Volume: 11
Issue: 1
Pages: 2306
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Publication
17267404 | J:121664
First Author: Bruhat A
Year: 2007
Journal: Nucleic Acids Res
Title: ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation.
Volume: 35
Issue: 4
Pages: 1312-21
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Publication
17699753 | J:123909
First Author: Breitwieser W
Year: 2007
Journal: Genes Dev
Title: Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells.
Volume: 21
Issue: 16
Pages: 2069-82
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Publication
24338393 | J:237468
First Author: Wang LS
Year: 2013
Journal: Genet Mol Res
Title: Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations.
Volume: 12
Issue: 4
Pages: 5992-6005
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Publication
21533046 | J:172398
First Author: Ackermann J
Year: 2011
Journal: PLoS One
Title: Loss of ATF2 function leads to cranial motoneuron degeneration during embryonic mouse development.
Volume: 6
Issue: 4
Pages: e19090
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GXD Expression
GXD Expression
   
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189820
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Atf2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189820
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Atf2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189820
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Atf2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189820
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Atf2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189820
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Atf2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189820
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Atf2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6167888
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189820
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Atf2
Detected: true
Specimen Num: 7
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Publication
9488727 | J:46207
First Author: Firestein R
Year: 1998
Journal: J Biol Chem
Title: Association of activating transcription factor 2 (ATF2) with the ubiquitin-conjugating enzyme hUBC9. Implication of the ubiquitin/proteasome pathway in regulation of ATF2 in T cells.
Volume: 273
Issue: 10
Pages: 5892-902
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Protein
P16951
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
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Protein
Q8BN75
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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Protein
G3UXC3
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: false
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Protein
Q8CBR9
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
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Protein
Q8BQY2
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
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Protein
P70299
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: true
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Protein
A2AQF1
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
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Protein
Q3UT24
Organism: Mus musculus/domesticus
Length: 240  
Fragment?: false
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Protein
A2AQE9
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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Protein
Q3UKS5
Organism: Mus musculus/domesticus
Length: 378  
Fragment?: false
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Protein
A2AQF0
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: true
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Protein
F6Z2B2
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: true
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Protein
Q3US39
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
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Protein
Q543G2
Organism: Mus musculus/domesticus
Length: 447  
Fragment?: false
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Publication
18700251 | -
First Author: Chen SY
Year: 2008
Journal: J Cutan Pathol
Title: Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous angiosarcoma and pyogenic granuloma.
Volume: 35
Issue: 8
Pages: 722-30
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Publication
15878807 | -
First Author: Pearson AG
Year: 2005
Journal: Neuroscience
Title: Activating transcription factor 2 expression in the adult human brain: association with both neurodegeneration and neurogenesis.
Volume: 133
Issue: 2
Pages: 437-51
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Publication
18227516 | J:131564
First Author: Bhoumik A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Suppressor role of activating transcription factor 2 (ATF2) in skin cancer.
Volume: 105
Issue: 5
Pages: 1674-9
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Publication
1531847 | J:49483
First Author: Lee MR
Year: 1992
Journal: J Immunol
Title: Isolation and characterization of nuclear proteins that bind to T cell receptor V beta decamer motif.
Volume: 148
Issue: 6
Pages: 1906-12
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Publication
25456131 | J:315953
First Author: Gozdecka M
Year: 2014
Journal: Cell Rep
Title: JNK suppresses tumor formation via a gene-expression program mediated by ATF2.
Volume: 9
Issue: 4
Pages: 1361-74
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Publication
19584270 | J:150642
First Author: Liu Y
Year: 2009
Journal: Cancer Res
Title: Activating transcription factor 2 and c-Jun-mediated induction of FoxP3 for experimental therapy of mammary tumor in the mouse.
Volume: 69
Issue: 14
Pages: 5954-60
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Publication
22542937 | J:184435
First Author: Kawai S
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Negative regulation of Odd-skipped related 2 by TGF-beta achieves the induction of cellular migration and the arrest of cell cycle.
Volume: 421
Issue: 4
Pages: 696-700
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Publication
22439931 | J:189346
First Author: Su L
Year: 2012
Journal: Cancer Cell
Title: Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics.
Volume: 21
Issue: 3
Pages: 333-47
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Publication
12215258 | J:78567
First Author: Lin WC
Year: 2002
Journal: DNA Cell Biol
Title: Transcriptional activation of C/EBPbeta gene by c-Jun and ATF2.
Volume: 21
Issue: 8
Pages: 551-60
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Publication
19712269 | J:153077
First Author: Satake H
Year: 2009
Journal: Dev Growth Differ
Title: Spatio-temporal expression of activating transcription factor 5 in the skeletal development of mouse limb.
Volume: 51
Issue: 7
Pages: 669-76
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Publication
19793891 | J:153960
First Author: Blank U
Year: 2009
Journal: Development
Title: BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanism.
Volume: 136
Issue: 21
Pages: 3557-66
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Protein Coding Gene
MGP_CAROLIEiJ_G0023663 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025841 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025819 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025787 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025813 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025573 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_109349 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025037 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025554 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025685 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025647 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025773 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025678 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026317 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024778 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025115 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024586 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1531087 | J:49688
First Author: Georgopoulos K
Year: 1992
Journal: Mol Cell Biol
Title: Functionally distinct isoforms of the CRE-BP DNA-binding protein mediate activity of a T-cell-specific enhancer.
Volume: 12
Issue: 2
Pages: 747-57
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Publication
8538792 | J:30611
First Author: Reimold AM
Year: 1996
Journal: Nature
Title: Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice.
Volume: 379
Issue: 6562
Pages: 262-5
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Publication
11157857 | J:67176
First Author: Reimold AM
Year: 2001
Journal: Int Immunol
Title: Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice.
Volume: 13
Issue: 2
Pages: 241-8
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Publication
17189429 | J:118986
First Author: Maekawa T
Year: 2007
Journal: Mol Cell Biol
Title: Reduced levels of ATF-2 predispose mice to mammary tumors.
Volume: 27
Issue: 5
Pages: 1730-44
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Publication
24013026 | J:224964
 
First Author: de Vries MR
Year: 2013
Journal: J Mol Cell Cardiol
Title: C57BL/6 NK cell gene complex is crucially involved in vascular remodeling.
Volume: 64
Pages: 51-8
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Publication
10694580 | J:61178
First Author: Kim S
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: In vivo natural killer cell activities revealed by natural killer cell-deficient mice.
Volume: 97
Issue: 6
Pages: 2731-6
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Publication
17604094 | J:137640
First Author: French AR
Year: 2007
Journal: J Allergy Clin Immunol
Title: Chronic lymphocytosis of functionally immature natural killer cells.
Volume: 120
Issue: 4
Pages: 924-31
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GXD Expression
GXD Expression
     
Probe: MGI:1303109
Assay Type: Northern blot
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1329106
Age: embryonic day 12.5
Specimen Label: 12
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:1303109
Assay Type: Northern blot
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:1329106
Age: embryonic day 14.5
Specimen Label: 13
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
   
Probe: MGI:3784249
Assay Type: RT-PCR
Annotation Date: 2008-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654814
Stage: TS14
Assay Id: MGI:3784412
Age: embryonic day 9.0
Image: 4
Specimen Label: 16-20s
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3784249
Assay Type: RT-PCR
Annotation Date: 2008-05-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654815
Stage: TS15
Assay Id: MGI:3784412
Age: embryonic day 9.5
Image: 4
Specimen Label: 26-30s
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816421
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816421
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816421
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816421
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816421
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816421
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816421
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3815617
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816421
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:4458357
Assay Type: RT-PCR
Annotation Date: 2010-07-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:4458364
Age: postnatal
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4458357
Assay Type: RT-PCR
Annotation Date: 2010-07-09
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2576528
Stage: TS28
Assay Id: MGI:4458364
Age: postnatal
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4458367
Assay Type: Northern blot
Annotation Date: 2010-07-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4458368
Age: postnatal
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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